Research Topics
Species | J PendersSummaryAffiliation: Maastricht University Country: The Netherlands Publications
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Detail Information
Publications
Quantification of Bifidobacterium spp., Escherichia coli and Clostridium difficile in faecal samples of breast-fed and formula-fed infants by real-time PCRJohn Penders
Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM, Maastricht University, 6200 MD Maastricht, The Netherlands
FEMS Microbiol Lett 243:141-7. 2005..difficile as well as E. coli are significantly lower in the gut microbiota of breast-fed infants than in that of formula-fed infants, whereas the prevalence and counts of Bifidobacterium spp. is similar among both groups...
Host-microbial interactions in childhood atopy: toll-like receptor 4 (TLR4), CD14, and fecal Escherichia coliJohn Penders
Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht and Care and Public Health Research Institute, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
J Allergy Clin Immunol 125:231-6.e1-5. 2010..It is likely that particularly gene-environmental interactions in early life determine the development of atopy...
Factors influencing the composition of the intestinal microbiota in early infancyJohn Penders
Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, Netherlands
Pediatrics 118:511-21. 2006..The aim of this study was to examine the contribution of a broad range of external influences to the gut microbiotic composition in early infancy...
Gut microbiota composition and development of atopic manifestations in infancy: the KOALA Birth Cohort StudyJohn Penders
Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
Gut 56:661-7. 2007..We examined gut microbiota composition in early infancy and the subsequent development of atopic manifestations and sensitisation...
Molecular fingerprinting of the intestinal microbiota of infants in whom atopic eczema was or was not developingJ Penders
Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, Maastricht, The Netherlands
Clin Exp Allergy 36:1602-8. 2006..The rise in atopic diseases has been linked to disturbances in the intestinal microbiota composition...
Antibiotic resistance of motile aeromonads in indoor catfish and eel farms in the southern part of The NetherlandsJ Penders
Nutrition and Toxicology Research Institute Maastricht, Department of Epidemiology, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
Int J Antimicrob Agents 31:261-5. 2008..This reservoir might form a risk for human health and has major consequences for the effectiveness of this antibiotic in the treatment of infectious diseases in fish...
The role of the intestinal microbiota in the development of atopic disordersJ Penders
Department of Epidemiology, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, Maastricht, The Netherlands
Allergy 62:1223-36. 2007..To gain more insight into the role of the gut microbiota in the etiology of atopy, large-scale prospective birth cohort studies using molecular methods to study the gut microbiota are needed...
Cytokines and soluble CD14 in breast milk in relation with atopic manifestations in mother and infant (KOALA Study)B E P Snijders
Care and Public Health Research Institute Caphri, Department of Epidemiology, Maastricht University, Maastricht, The Netherlands
Clin Exp Allergy 36:1609-15. 2006..Conflicting evidence exists concerning the protective role of breastfeeding in allergy and atopic disease aetiology. Breast milk contains biologically active molecules influencing the innate immune system of newborns...
Consumption of organic foods and risk of atopic disease during the first 2 years of life in the NetherlandsIscha Kummeling
Department of Epidemiology, Care and Public Health Research Institute Caphri, Maastricht University, Maastricht, The Netherlands
Br J Nutr 99:598-605. 2008..Further studies to substantiate these results are warranted...
Inhibition of human glutathione S-transferase P1-1 by tocopherols and alpha-tocopherol derivativesR I van Haaften
Department of Pharmacology and Toxicology, Faculty of Medicine, Universiteit Maastricht, P O Box 616, 6200 MD Maastricht, Netherlands
Biochim Biophys Acta 1548:23-8. 2001..This indicates that the GST P1-1 enzyme is non-competitively inhibited by RRR-alpha-tocopherol acetate. The potential implications of GST P1-1 inhibition by tocopherol and alpha-tocopherol derivatives are discussed...
Early life exposure to antibiotics and the subsequent development of eczema, wheeze, and allergic sensitization in the first 2 years of life: the KOALA Birth Cohort StudyIscha Kummeling
Department of Epidemiology, Maastricht University, PO Box 616, 6200 Maastricht, The Netherlands
Pediatrics 119:e225-31. 2007..We evaluated early life exposure to antibiotics and the subsequent development of eczema, wheeze, and allergic sensitization in infancy...
Breast-feeding duration and infant atopic manifestations, by maternal allergic status, in the first 2 years of life (KOALA study)Bianca E P Snijders
Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands
J Pediatr 151:347-51, 351.e1-2. 2007..To investigate the potential effect of modification by maternal allergic status on the relationship between breast-feeding duration and infant atopic manifestations in the first 2 years of life...
Breastfeeding and infant eczema in the first year of life in the KOALA birth cohort study: a risk period-specific analysisBianca E P Snijders
Care and Public Health Research Institute, Maastricht University, PO Box 616, 6200 Maastricht, The Netherlands
Pediatrics 119:e137-41. 2007..We studied the association between breastfeeding and eczema, taking into account the possible influence of reverse causation, with risk period-specific analyses...
Etiology of atopy in infancy: the KOALA Birth Cohort StudyIscha Kummeling
Department of Epidemiology, Care and Public Health Research Institute Caphri, Maastricht University, Maastricht, The Netherlands
Pediatr Allergy Immunol 16:679-84. 2005..Mid 2006 we expect to report our first results on the relationship between the various exposures in early life and childhood atopy. An outline of the focus and design of the KOALA Birth Cohort Study is presented...
Timing of infection and development of wheeze, eczema, and atopic sensitization during the first 2 yr of life: the KOALA Birth Cohort StudyMonique Mommers
Department of Epidemiology, School for Public Health and Primary Care CAPHRI, Maastricht University, Maastricht, The Netherlands
Pediatr Allergy Immunol 21:983-9. 2010..94 (95% CI 1.36-11.40) compared to children without diarrhea. Infections becoming clinically manifest during the first 3 months of life may be a general marker for a wheezy phenotype...
Infant antibiotic use and wheeze and asthma risk: a systematic review and meta-analysisJ Penders
Department of Medical Microbiology, Maastricht University Medical Centre, P O Box 5800, NL 6202 AZ, Maastricht, The Netherlands
Eur Respir J 38:295-302. 2011..Association was weak when fully adjusted for these types of bias. Heterogeneity of disease definition between studies could affect the results...
Maternal fatty acid status in pregnancy and childhood atopic manifestations: KOALA Birth Cohort StudyM L Notenboom
Department of Epidemiology, CAPHRI School of Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands
Clin Exp Allergy 41:407-16. 2011..Prenatal exposure to a pro-inflammatory fatty acid status is hypothesized although little research has been carried out...
Predictive value of Escherichia coli susceptibility in strains causing asymptomatic bacteriuria for women with recurrent symptomatic urinary tract infections receiving prophylaxisM A J Beerepoot
Division of Infectious Diseases, Tropical Medicine and AIDS, Department of Internal Medicine, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre, Amsterdam, The Netherlands
Clin Microbiol Infect 18:E84-90. 2012..However, the susceptibility pattern of E. coli strains isolated in the month before a symptomatic E. coli UTI can be used to make informed choices for empirical antibiotic treatment in this patient population...
