C R Markus

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi request reprint Review: Serotonin by stress interaction: a susceptibility factor for the development of depression?
    Christine Firk
    Department of Experimental Psychology, Maastricht University, Maastricht, The Netherlands
    J Psychopharmacol 21:538-44. 2007
  2. ncbi request reprint Effects of carbohydrates on brain tryptophan availability and stress performance
    C R Markus
    Department of Biological Psycholoy and Psychopharmacology, University Maastricht, P O Box 6200, MD Maastricht, The Netherlands
    Biol Psychol 76:83-90. 2007
  3. doi request reprint Contribution of the 5-HTTLPR gene by neuroticism on weight gain in male and female participants
    C Rob Markus
    Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Psychiatr Genet 22:279-85. 2012
  4. doi request reprint Differential effect of the 5-HTT gene-linked polymorphic region on emotional eating during stress exposure following tryptophan challenge
    C Rob Markus
    Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    J Nutr Biochem 23:410-6. 2012
  5. pmc Differential effects of 5-HTTLPR genotypes on inhibition of negative emotional information following acute stress exposure and tryptophan challenge
    C Rob Markus
    Faculty of Psychology and Neuroscience, Department of Neuropsychology and Psychopharmacology, Universiteitssingel, Maastricht, The Netherlands
    Neuropsychopharmacology 36:819-26. 2011
  6. doi request reprint Effect of tryptophan-rich egg protein hydrolysate on brain tryptophan availability, stress and performance
    C Rob Markus
    Department of Neuropsychology and Psychopharmacology, Maastricht University, The Netherlands
    Clin Nutr 29:610-6. 2010
  7. doi request reprint Differential effects of tri-allelic 5-HTTLPR polymorphisms in healthy subjects on mood and stress performance after tryptophan challenge
    C Rob Markus
    Faculty of Psychology and Neuroscience, Department of Neuropsychology and Psychopharmacology, University Maastricht, Maastricht, Netherlands
    Neuropsychopharmacology 34:2667-74. 2009
  8. doi request reprint Effect of different tryptophan sources on amino acids availability to the brain and mood in healthy volunteers
    C Rob Markus
    Department of Neuropsychology and Psychopharmacology, Faculty of Psychology, Maastricht University, Maastricht, The Netherlands
    Psychopharmacology (Berl) 201:107-14. 2008
  9. doi request reprint Dietary amino acids and brain serotonin function; implications for stress-related affective changes
    C Rob Markus
    Department of Neuropsychology and Psychopharmacology, University of Maastricht, P O Box 6200, Maastricht, MD, The Netherlands
    Neuromolecular Med 10:247-58. 2008
  10. ncbi request reprint Attention switching after dietary brain 5-HT challenge in high impulsive subjects
    C Rob Markus
    Department of Experimental Psychology, University of Maastricht, The Netherlands
    J Psychopharmacol 21:700-8. 2007

Detail Information

Publications22

  1. ncbi request reprint Review: Serotonin by stress interaction: a susceptibility factor for the development of depression?
    Christine Firk
    Department of Experimental Psychology, Maastricht University, Maastricht, The Netherlands
    J Psychopharmacol 21:538-44. 2007
    ....
  2. ncbi request reprint Effects of carbohydrates on brain tryptophan availability and stress performance
    C R Markus
    Department of Biological Psycholoy and Psychopharmacology, University Maastricht, P O Box 6200, MD Maastricht, The Netherlands
    Biol Psychol 76:83-90. 2007
    ..Cold pressor stress significantly increased cortisol and reduced mood and cognitive performance, whereas carbohydrates significantly increased plasma Trp/LNAA and positively influenced performance and mood under stress...
  3. doi request reprint Contribution of the 5-HTTLPR gene by neuroticism on weight gain in male and female participants
    C Rob Markus
    Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Psychiatr Genet 22:279-85. 2012
    ..However, considerable variability has been apparent to replicate these findings...
  4. doi request reprint Differential effect of the 5-HTT gene-linked polymorphic region on emotional eating during stress exposure following tryptophan challenge
    C Rob Markus
    Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    J Nutr Biochem 23:410-6. 2012
    ..Conclusions: Since TPH caused a greater increase in the plasma TRP/large neutral amino acid ratio in the L'/L' group compared to S'/S' group, the exclusive beneficial effects of L'/L' genotype may be due to enhanced brain 5-HT function...
  5. pmc Differential effects of 5-HTTLPR genotypes on inhibition of negative emotional information following acute stress exposure and tryptophan challenge
    C Rob Markus
    Faculty of Psychology and Neuroscience, Department of Neuropsychology and Psychopharmacology, Universiteitssingel, Maastricht, The Netherlands
    Neuropsychopharmacology 36:819-26. 2011
    ..Moreover, current data suggest that L'/L'-allele genotypes are more resilient, even increasing cognitive emotional (inhibitory) control after stress...
  6. doi request reprint Effect of tryptophan-rich egg protein hydrolysate on brain tryptophan availability, stress and performance
    C Rob Markus
    Department of Neuropsychology and Psychopharmacology, Maastricht University, The Netherlands
    Clin Nutr 29:610-6. 2010
    ..The aim of the present study was to investigate the effects of EPH compared to placebo protein on plasma amino acids, stress coping and performance in subjects with high and low chronic stress vulnerabilities...
  7. doi request reprint Differential effects of tri-allelic 5-HTTLPR polymorphisms in healthy subjects on mood and stress performance after tryptophan challenge
    C Rob Markus
    Faculty of Psychology and Neuroscience, Department of Neuropsychology and Psychopharmacology, University Maastricht, Maastricht, Netherlands
    Neuropsychopharmacology 34:2667-74. 2009
    ..This apparent genetic 5-HT vulnerability may become a meaningful risk factor for depression when brain 5-HT falls below functional need in the face of real severe stressful life events...
  8. doi request reprint Effect of different tryptophan sources on amino acids availability to the brain and mood in healthy volunteers
    C Rob Markus
    Department of Neuropsychology and Psychopharmacology, Faculty of Psychology, Maastricht University, Maastricht, The Netherlands
    Psychopharmacology (Berl) 201:107-14. 2008
    ..The effects of ALAC remain rather modest, and alternative protein sources of tryptophan may be more effective...
  9. doi request reprint Dietary amino acids and brain serotonin function; implications for stress-related affective changes
    C Rob Markus
    Department of Neuropsychology and Psychopharmacology, University of Maastricht, P O Box 6200, Maastricht, MD, The Netherlands
    Neuromolecular Med 10:247-58. 2008
    ....
  10. ncbi request reprint Attention switching after dietary brain 5-HT challenge in high impulsive subjects
    C Rob Markus
    Department of Experimental Psychology, University of Maastricht, The Netherlands
    J Psychopharmacol 21:700-8. 2007
    ....
  11. ncbi request reprint Whey protein rich in alpha-lactalbumin increases the ratio of plasma tryptophan to the sum of the other large neutral amino acids and improves cognitive performance in stress-vulnerable subjects
    C Rob Markus
    Department of Experimental Psychology, University of Maastricht, Maastricht, The Netherlands
    Am J Clin Nutr 75:1051-6. 2002
    ..In addition, a diet-induced increase in tryptophan may increase brain serotonergic activity levels and improve cognitive performance, particularly in high stress-vulnerable subjects...
  12. ncbi request reprint Effects of Ginkgo biloba on corticosterone stress responses after inescapable shock exposure in the rat
    C Rob Markus
    Department of Experimental Psychology, University of Maastricht, PO Box 6200 MD Maastricht, The Netherlands
    Pharmacol Biochem Behav 76:487-92. 2003
    ..biloba on improving behavioral stress adaptation and acquisition of active avoidance and on reducing behavioral deficits indicative of "learned helplessness."..
  13. ncbi request reprint Moderate whisky consumption in combination with an evening meal reduces tryptophan availability to the brain but does not influence performance in healthy volunteers
    C Rob Markus
    University of Maastricht, Department of Experimental Psychology, Maastricht, The Netherlands
    Br J Nutr 92:995-1000. 2004
    ..The present findings reveal that whisky consumption alters available plasma Trp for uptake into the brain, whereas there were no effects on mood and performance...
  14. ncbi request reprint Evening intake of alpha-lactalbumin increases plasma tryptophan availability and improves morning alertness and brain measures of attention
    C Rob Markus
    Department of Experimental Psychology and the Biomedical Center, University of Maastricht, Maastricht, Netherlands
    Am J Clin Nutr 81:1026-33. 2005
    ..Brain uptake of the serotonin precursor tryptophan is dependent on nutrients that influence the availability of tryptophan via a change in the ratio of plasma tryptophan to the sum of the other large neutral amino acids (Trp:LNAA)...
  15. ncbi request reprint Memory function in women with premenstrual complaints and the effect of serotonergic stimulation by acute administration of an alpha-lactalbumin protein
    Jeroen A J Schmitt
    Experimental Psychopharmacology Unit, Brain and Behaviour Institute, Universiteit Maastricht, Maastricht, The Netherlands, Nestle Research Center, Lausanne, Switzerland
    J Psychopharmacol 19:375-84. 2005
    ..The data suggest that serotonergic hypofunction may play a role in premenstrual memory decline, but serotonergic mechanisms cannot fully account for observed cognitive changes in the premenstrual phase...
  16. doi request reprint Effects of an acute alpha-lactalbumin manipulation on mood and food hedonics in high- and low-trait anxiety individuals
    Ellen Verschoor
    Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
    Br J Nutr 104:595-602. 2010
    ..These individuals expressed a lower liking (P = 0.012) and SW food preference (P = 0.014) after the stressful task when supplemented with LAC...
  17. doi request reprint Mood and cortisol responses following tryptophan-rich hydrolyzed protein and acute stress in healthy subjects with high and low cognitive reactivity to depression
    Christine Firk
    Department of Clinical Psychological Science, Maastricht University, Maastricht, The Netherlands
    Clin Nutr 28:266-71. 2009
    ..We hypothesized that subjects with high CR are more responsive to the beneficial effects of HP than subjects with low CR particularly after acute stress exposure...
  18. doi request reprint Differential effects of 5-HTTLPR genotypes on mood, memory, and attention bias following acute tryptophan depletion and stress exposure
    Christine Firk
    Department of Clinical Psychological Science, Faculty of Psychology and Neuroscience, Maastricht University, P O Box 616, 6200, MD, Maastricht, The Netherlands
    Psychopharmacology (Berl) 203:805-18. 2009
    ..Polymorphisms of the serotonin transporter gene (5-HTTLPR) may be associated with increased vulnerability to acute tryptophan depletion (ATD) and depression vulnerability especially following stressful life events...
  19. pmc Effects of acute tryptophan depletion on affective processing in first-degree relatives of depressive patients and controls after exposure to uncontrollable stress
    Christine Firk
    Department of Clinical Psychological Science, Faculty of Psychology, Maastricht University, Maastricht, The Netherlands
    Psychopharmacology (Berl) 199:151-60. 2008
    ..Based on previous data, it is suggested that stress may be a mediating factor...
  20. ncbi request reprint Methylphenidate improves deficient error evaluation in children with ADHD: an event-related brain potential study
    Lisa M Jonkman
    Faculty of Psychology, Department of Cognitive Neuroscience, Maastricht University, Maastricht, The Netherlands
    Biol Psychol 76:217-29. 2007
    ..Methylphenidate's ameliorating effects might be established through its influence on brain networks including posterior (parietal) cortex, enabling children with ADHD to allocate more attention to significant events...
  21. ncbi request reprint Serotonergic vulnerability and depression: assumptions, experimental evidence and implications
    L A W Jans
    Faculty of Psychology, Department of Neurocognition, Maastricht University, Maastricht, The Netherlands
    Mol Psychiatry 12:522-43. 2007
    ....
  22. ncbi request reprint Diet rich in alpha-lactalbumin improves memory in unmedicated recovered depressed patients and matched controls
    Linda Booij
    Department of Psychology, Leiden University, Leiden, The Netherlands
    J Psychopharmacol 20:526-35. 2006
    ..The present findings should be further examined in different (e.g. medicated) samples. The long-term effects of alpha-lactalbumin should also be investigated...