Machteld Marcelis

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi request reprint Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia
    Machteld Marcelis
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Schizophr Res 86:45-53. 2006
  2. ncbi request reprint FKBP5 as a possible moderator of the psychosis-inducing effects of childhood trauma
    Dina Collip
    Department of Psychiatry and Psychology, School of Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands
    Br J Psychiatry 202:261-8. 2013
  3. ncbi request reprint Searching for a structural endophenotype in psychosis using computational morphometry
    Machteld Marcelis
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Psychiatry Res 122:153-67. 2003
  4. pmc Brain-derived neurotrophic factor/FK506-binding protein 5 genotype by childhood trauma interactions do not impact on hippocampal volume and cognitive performance
    Dennis Hernaus
    Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, School for Mental Health and NeuroScience MHeNS Maastricht University, Maastricht, The Netherlands
    PLoS ONE 9:e92722. 2014
  5. doi request reprint Childhood trauma and psychosis: a case-control and case-sibling comparison across different levels of genetic liability, psychopathology, and type of trauma
    Manuela Heins
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, South Limburg Mental Health Research and Teaching Network, Maastricht, The Netherlands
    Am J Psychiatry 168:1286-94. 2011
  6. pmc Delta-9-tetrahydrocannabinol-induced dopamine release as a function of psychosis risk: 18F-fallypride positron emission tomography study
    Rebecca Kuepper
    Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 8:e70378. 2013
  7. doi request reprint Microstructural white matter alterations in psychotic disorder: a family-based diffusion tensor imaging study
    Patrick A E Domen
    Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, The Netherlands
    Schizophr Res 146:291-300. 2013
  8. ncbi request reprint Subtle fluctuations in psychotic phenomena as functional states of abnormal dopamine reactivity in individuals at risk
    Inez Myin-Germeys
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Biol Psychiatry 58:105-10. 2005
  9. ncbi request reprint Brainstem response to hypercapnia: A symptom provocation study into the pathophysiology of panic disorder
    Liesbet Goossens
    1Department of Psychiatry and Psychology, European Graduate School of Neuroscience EURON, Maastricht University, Maastricht, The Netherlands
    J Psychopharmacol 28:449-56. 2014
  10. pmc Replicated evidence of absence of association between serum S100B and (risk of) psychotic disorder
    Christine van der Leeuw
    Department of Psychiatry and Psychology, School for Mental Health and Neuroscience, European Graduate School of Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands
    PLoS ONE 8:e82535. 2013

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia
    Machteld Marcelis
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Schizophr Res 86:45-53. 2006
    ..Relationship to prefrontal cortex volume. Arch. Gen. Psychiatry 50(7), 541-550] reported that lower prefrontal cortex volume was associated with altered metabolic stress response, but this finding has never been replicated...
  2. ncbi request reprint FKBP5 as a possible moderator of the psychosis-inducing effects of childhood trauma
    Dina Collip
    Department of Psychiatry and Psychology, School of Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands
    Br J Psychiatry 202:261-8. 2013
    ..FK506 binding protein 5 (FKBP5) has repeatedly been shown to be a critical determinant of post-traumatic stress disorder (PTSD) and depression following childhood trauma...
  3. ncbi request reprint Searching for a structural endophenotype in psychosis using computational morphometry
    Machteld Marcelis
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Psychiatry Res 122:153-67. 2003
    ..Patients with psychosis and first-degree healthy relatives of patients with psychosis show cerebellar abnormalities, which may constitute a marker of genetic transmission...
  4. pmc Brain-derived neurotrophic factor/FK506-binding protein 5 genotype by childhood trauma interactions do not impact on hippocampal volume and cognitive performance
    Dennis Hernaus
    Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, School for Mental Health and NeuroScience MHeNS Maastricht University, Maastricht, The Netherlands
    PLoS ONE 9:e92722. 2014
    ..The importance of appropriate statistical designs and inclusion of relevant covariates should be carefully considered. ..
  5. doi request reprint Childhood trauma and psychosis: a case-control and case-sibling comparison across different levels of genetic liability, psychopathology, and type of trauma
    Manuela Heins
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, South Limburg Mental Health Research and Teaching Network, Maastricht, The Netherlands
    Am J Psychiatry 168:1286-94. 2011
    ..The associations of two types of childhood trauma (abuse and neglect) with psychosis symptom domains were investigated in subjects with psychotic illness, high psychosis vulnerability, and average psychosis vulnerability...
  6. pmc Delta-9-tetrahydrocannabinol-induced dopamine release as a function of psychosis risk: 18F-fallypride positron emission tomography study
    Rebecca Kuepper
    Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 8:e70378. 2013
    ..This was most pronounced in caudate nucleus. This is the first study to demonstrate differential sensitivity to Δ(9)-THC in terms of increased endogenous dopamine release in individuals at risk for psychosis. ..
  7. doi request reprint Microstructural white matter alterations in psychotic disorder: a family-based diffusion tensor imaging study
    Patrick A E Domen
    Department of Psychiatry and Psychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University Medical Centre, The Netherlands
    Schizophr Res 146:291-300. 2013
    ..Less is known about the presence and role of white matter alterations in well individuals at higher than average genetic risk for psychotic disorder...
  8. ncbi request reprint Subtle fluctuations in psychotic phenomena as functional states of abnormal dopamine reactivity in individuals at risk
    Inez Myin-Germeys
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Biol Psychiatry 58:105-10. 2005
    ..It was investigated whether this psychotic reactivity in individuals at risk for psychosis is the exophenotypic expression of an underlying endophenotype characterized by a hyperreactive dopamine (DA) system...
  9. ncbi request reprint Brainstem response to hypercapnia: A symptom provocation study into the pathophysiology of panic disorder
    Liesbet Goossens
    1Department of Psychiatry and Psychology, European Graduate School of Neuroscience EURON, Maastricht University, Maastricht, The Netherlands
    J Psychopharmacol 28:449-56. 2014
    ..Conclusion: This is the first study showing that the behavioural response to CO2 that characterises panic disorder patients is likely due to increased neural sensitivity to CO2 at brainstem level. ..
  10. pmc Replicated evidence of absence of association between serum S100B and (risk of) psychotic disorder
    Christine van der Leeuw
    Department of Psychiatry and Psychology, School for Mental Health and Neuroscience, European Graduate School of Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands
    PLoS ONE 8:e82535. 2013
    ..It remains unclear whether S100B elevation, which possibly reflects glial dysfunction, is the consequence of disease or compensatory processes, or whether it is an indicator of familial risk...
  11. pmc The effects of FreeSurfer version, workstation type, and Macintosh operating system version on anatomical volume and cortical thickness measurements
    Ed H B M Gronenschild
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, Alzheimer Center Limburg, The Netherlands
    PLoS ONE 7:e38234. 2012
    ..Moreover, in view of the large and significant cross-version differences, it is concluded that formal assessment of the accuracy of FreeSurfer is desirable...
  12. ncbi request reprint Does normal developmental expression of psychosis combine with environmental risk to cause persistence of psychosis? A psychosis proneness-persistence model
    Audrey Cougnard
    INSERM U 657, University Victor Segalen Bordeaux 2, IFR99 of Public Health, Bordeaux, France
    Psychol Med 37:513-27. 2007
    ....
  13. ncbi request reprint Nonreplication of the association between ab-ridge count and cerebral structural measures in schizophrenia
    Araceli Rosa
    Unitat d Antropologia, Facultat de Biologia, Universitat de Barcelona, Spain
    Compr Psychiatry 44:459-61. 2003
    ..The present findings do not support the hypothesis that the changes in brain volume seen in patients with schizophrenia are of prenatal origin...