Research Topics
| J A KnottnerusSummaryAffiliation: Maastricht University Country: The Netherlands Publications
| Collaborators
|
Detail Information
Publications
Comparative effectiveness research: challenges for medical journalsHarold C Sox
Dartmouth Institute, Dartmouth Medical School, Hanover, New Hampshire, USA
Trials 11:45. 2010....- Does a competitive voucher program for adolescents improve the quality of reproductive health care? A simulated patient study in NicaraguaLiesbeth E Meuwissen
Instituto CentroAmericano de Salud, Postal 2234, Managua, Nicaragua
BMC Public Health 6:204. 2006..This study evaluates the impact and sustainability of a competitive voucher program on the quality of SRH care for poor and underserved female adolescents and the usefulness of the simulated patient (SP) method for such evaluation... - Active rehabilitation for chronic low back pain: cognitive-behavioral, physical, or both? First direct post-treatment results from a randomized controlled trial [ISRCTN22714229]Rob J E M Smeets
Rehabilitation Centre Blixembosch, Eindhoven, The Netherlands
BMC Musculoskelet Disord 7:5. 2006..A direct comparison of a physical, a cognitive-behavioral treatment and a combination of both has never been carried out so far... - Pragmatic trials in primary care. Methodological challenges and solutions demonstrated by the DIAMOND-studyGerdine A J Fransen
Research Institute Caphri, Department of General Practice, Maastricht University, MD Maastricht, The Netherlands
BMC Med Res Methodol 7:16. 2007..From the successes as well as the problems we experienced the quality of future pragmatic trials may benefit... - Serotonin receptor 3A polymorphism c.-42C > T is associated with severe dyspepsiaSuhreta Mujakovic
University Medical Centre Utrecht, Department of Gastroenterology and Hepatology, The Netherlands
BMC Med Genet 12:140. 2011..We investigated the association between these functional polymorphisms and dyspeptic symptom severity... - Chronic non-specific abdominal complaints in general practice: a prospective study on management, patient health status and course of complaintsHenriëtte A M van den Heuvel-Janssen
Department of General Practice, Research Institute Caphri, Maastricht University, Maastricht, The Netherlands
BMC Fam Pract 7:12. 2006..Aim of this study was to present a primary care based profile of these chronic complaints including health care involvement, health status and clinical course... - Challenges in dia-prognostic researchJ A Knottnerus
Netherlands School of Primary Care Research, University of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
J Epidemiol Community Health 56:340-1. 2002 
Assessment of the accuracy of diagnostic tests: the cross-sectional studyJ A Knottnerus
University of Maastricht, Netherlands School of Primary Care Research, Post Office Box 616, 6200 MD Maastricht, The Netherlands
J Clin Epidemiol 56:1118-28. 2003..Also, systematic reviews and meta-analysis have a role. To enable readers of diagnostic research reports to evaluate whether methodological key issues were addressed, authors are advised to follow the STARD guidelines...- Between iatrotropic stimulus and interiatric referral: the domain of primary care researchJ Andre Knottnerus
Netherlands School of Primary Care, Research University of Maastricht, P O Box 616 6200, MD Maastricht 31 43 3882319, The Netherlands
J Clin Epidemiol 55:1201-6. 2002..Although Feinstein was a clinical specialist and has always lived in a country without a very strong primary care tradition, he not only recognized the value of primary care research but also substantially contributed to its development... - Evaluation of diagnostic proceduresJ Andre Knottnerus
Netherlands School of Primary Care Research, PO Box 616, 6200 MD Maastricht, The Netherlands
BMJ 324:477-80. 2002 - Clinical items not helpful in differentiating viral from bacterial lower respiratory tract infections in general practiceR M Hopstaken
Department of General Practice, Maastricht University, Care and Public Health Research Institute, PO Box 616, Maastricht 6200 MD, The Netherlands
J Clin Epidemiol 58:175-83. 2005..Whether this is possible is often doubted but has rarely been studied in general practice... - Psychological characteristics of patients with newly developed psychogenic seizuresT van Merode
Department of General Practice, Maastricht University, The Netherlands
J Neurol Neurosurg Psychiatry 75:1175-7. 2004..To assess psychopathological symptoms and history of childhood trauma in patients with newly developed psychogenic seizures... - Compliance of asthmatic families with a primary prevention programme of asthma and effectiveness of measures to reduce inhalant allergens--a randomized trialH J A M Schönberger
Department of General Practice, Research Institute Caphri, University Maastricht, Maastricht, The Netherlands
Clin Exp Allergy 34:1024-31. 2004..Compliance to and the effect of pre- and post-natal exposure reduction measures to prevent asthma in high-risk children from asthmatic families were studied... - The PREVASC study: the clinical effect of a multifaceted educational intervention to prevent childhood asthmaH J A M Schönberger
Dept of General Practice, Research Institute Caphri, University Maastricht, Maastricht, The Netherlands
Eur Respir J 25:660-70. 2005..Follow-up is necessary to confirm whether the intervention can actually prevent the development of asthma... - The validity and ethics of giving placebo in a randomized nonpharmacologic trial was evaluatedM G Spigt
Department of General Practice, University of Maastricht, Research Institute Caphri, P O Box 616, 6200 MD Maastricht, The Netherlands
J Clin Epidemiol 58:350-6. 2005..In a study on the effectiveness of increased water intake on voiding dysfunction in elderly men we used an unusual design. This article addresses the internal validty and ethics of this design... - Increasing the daily water intake for the prophylactic treatment of headache: a pilot trialM G Spigt
Department of General Practice, Research Institute Caphri, University of Maastricht, Maastricht, The Netherlands
Eur J Neurol 12:715-8. 2005..Our results seem to justify larger scaled research on the effectiveness of increased water intake in headache patients... - Lower prevalence of heart disease but higher mortality risk during follow-up was found among nonrespondents to a cohort studyM Y Veenstra
Addiction Research Institute, Erasmus University Rotterdam, Rotterdam, The Netherlands
J Clin Epidemiol 59:412-20. 2006..A secondary aim was to assess whether reasons for nonresponse were associated with health status at baseline... - The effects of 6 months of increased water intake on blood sodium, glomerular filtration rate, blood pressure, and quality of life in elderly (aged 55-75) menMark G Spigt
Department of General Practice, Research Institute Caphri, Maastricht University, Maastricht, The Netherlands
J Am Geriatr Soc 54:438-43. 2006..To study whether there are any negative or positive effects of 6 months of increased fluid intake in reasonably healthy elderly men... - Chronic fatigue syndrome-like caseness as a predictor of work status in fatigued employees on sick leave: four year follow up studyM J H Huibers
Department of Medical, Clinical and Experimental Psychology, Maastricht University, Maastricht, Netherlands
Occup Environ Med 63:570-2. 2006..To assess whether CFS-like caseness (meeting the criteria for chronic fatigue syndrome (CFS)) predicts work status in the long term... - Role of the electronic patient record in the development of general practice in The NetherlandsJ A Knottnerus
Dept of Primary Care, University of Maastricht, The Netherlands
Methods Inf Med 38:350-4. 1999..While the EPR is a useful tool to facilitate a better performance, it may enable the doctor to focus more on the health care essentials... - Similarities, overlap and differences between burnout and prolonged fatigue in the working populationS S Leone
Department of Epidemiology, Research Institute Caphri, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
QJM 100:617-27. 2007..Burnout and prolonged fatigue are related but distinct concepts that have seldom been empirically compared... - Can the 'hygiene hypothesis' be explained by confounding by behavior?C P van Schayck
Care and Public Health Research Institute, University of Maastricht, P O Box 616 6200, MD Maastricht, The Netherlands
J Clin Epidemiol 57:435-7. 2004 - Measurement of lifetime alcohol intake: utility of a self-administered questionnaireI H M Friesema
Department of Health Care Studies, Section of Medical Sociology, University of Maastricht, Maastricht, The Netherlands
Am J Epidemiol 159:809-17. 2004..Indices of validity were similar for men (0.75) and women (0.70). Results show that the LDH-q can be a useful instrument in large-scale cohort studies... - Pathophysiological aspects of bladder dysfunction: a new hypothesis for the prevention of 'prostatic' symptomsM G Spigt
Department of General Practice, Research Institute Caphri, University of Maastricht, P O Box 616, Maastricht MD 6200, The Netherlands
Med Hypotheses 62:448-52. 2004..Future symptoms may thus be prevented. In humans an increased urine output can be achieved by drinking additional water, which could be an adequate preventive intervention... - Somatisation in primary care: clinical judgement and standardised measurement comparedA F Schilte
Department of General Practice, University of Maastricht, The Netherlands
Soc Psychiatry Psychiatr Epidemiol 35:276-82. 2000..We investigated the relation between GPs' clinical judgement of somatisation and a somatisation research instrument (DSM-III-R), and examined how both operationalisations of somatisation related to other important variables... - Primary prevention of arterial thromboembolism in non-rheumatic atrial fibrillation in primary care: randomised controlled trial comparing two intensities of coumarin with aspirinB S Hellemons
Department of General Practice, University of Maastricht, 6200 MD Maastricht, Netherlands
BMJ 319:958-64. 1999..To investigate the effectiveness of aspirin and coumarin in preventing thromboembolism in patients with non-rheumatic atrial fibrillation in general practice... - Feasibility of a national cholesterol guideline in daily practice. A randomized controlled trial in 20 general practicesT van der Weijden
Centre for Quality of Care Research, University of Maastricht, The Netherlands
Int J Qual Health Care 11:131-7. 1999.... - Psychosocial patient characteristics and GP-registered chronic morbidity: a prospective studyM van den Akker
Department of General Practice, Maastricht University, P O Box 616, 6200 MD, Maastricht, The Netherlands
J Psychosom Res 50:95-102. 2001..We studied the incidence rates of morbidity and multimorbidity, and the influence of psychosocial characteristics on their occurrences... - Problems in determining occurrence rates of multimorbidityM van den Akker
Department of General Practice, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
J Clin Epidemiol 54:675-9. 2001..As some analyses are addressing multicomparisons, external validity testing is recommended... - Randomised controlled trial of disclosure of emotionally important events in somatisation in primary careA F Schilte
Department of General Practice, University of Maastricht, PO Box 616, 6200 MD Maastricht, Netherlands
BMJ 323:86. 2001..To test whether a disclosure intervention improves subjective health and reduces medical consumption and sick leave in somatising patients in general practice... - Indicators of childhood adversity in somatisation in general practiceA F Schilte
Department of General Practice, University of Maastricht, The Netherlands
Scand J Prim Health Care 19:232-6. 2001..To identify medical and psychosocial indicators of childhood adversity in somatising patients in primary care... - Fatigue, burnout, and chronic fatigue syndrome among employees on sick leave: do attributions make the difference?M J H Huibers
Department of Epidemiology, Maastricht University, Netherlands
Occup Environ Med 60:i26-31. 2003..However, these conditions have not been compared in empirical research, despite conceptual similarities... - Contributions of symptoms, signs, erythrocyte sedimentation rate, and C-reactive protein to a diagnosis of pneumonia in acute lower respiratory tract infectionR M Hopstaken
Department of General Practice, Maastricht University, Care and Public Health Research Institute, Maastricht, The Netherlands
Br J Gen Pract 53:358-64. 2003.... - Diagnostic value of signs and symptoms associated with peripheral arterial occlusive disease seen in general practice: a multivariable approachH E Stoffers
Department of General Practice, University of Limburg, Maastricht, The Netherlands
Med Decis Making 17:61-70. 1997.... - A risk model for the prediction of recurrent falls in community-dwelling elderly: a prospective cohort studyP A Stalenhoef
Department of General Practice, Maastricht University, Postbox 616, The Netherlands
J Clin Epidemiol 55:1088-94. 2002.... - Marginal impact of psychosocial factors on multimorbidity: results of an explorative nested case-control studyM van den Akker
Maastricht University, Department of General Practice, The Netherlands
Soc Sci Med 50:1679-93. 2000..Profiles for subjects at risk for morbidity and multimorbidity seem to differ... - Barriers in the care of patients who have experienced a traumatic event: the perspective of general practiceM van den Akker
Department of General Practice, ExTra, Research Institute for Extramural and Transmural Care, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
Fam Pract 18:214-6. 2001.... - Climacteric complaints in the communityL W Maartens
Diagnostic Centre Eindhoven, PO Box 6247, 5600 HG Eindhoven, Department of Family Medicine, University of Maastricht, The Netherlands
Fam Pract 18:189-94. 2001.... - Can a comprehensive voucher programme prompt changes in doctors' knowledge, attitudes and practices related to sexual and reproductive health care for adolescents? A case study from Latin AmericaLiesbeth E Meuwissen
Department of General Practice, University of Maastricht, The Netherlands
Trop Med Int Health 11:889-98. 2006..To evaluate whether participation in a competitive voucher programme designed to improve access to and quality of sexual and reproductive health care (SRH-care), prompted changes in doctors' knowledge, attitudes and practices... - Gender-related differences in non-epileptic attacks: a study of patients' cases in the literatureT van Merode
Department of General Practice, University of Maastricht, The Netherlands
Seizure 6:311-6. 1997..A prospective study on the incidence and phenomenology of pseudo-epileptic seizures in the general population is suggested to answer the new questions raised in this survey... - Community genetics and community medicineJ A Knottnerus
University of Maastricht, The Netherlands
Fam Pract 20:601-6. 2003....