Research Topics
Genomes and GenesSpecies | Reinout P HesselinkSummaryAffiliation: Maastricht University Country: The Netherlands Publications
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Detail Information
Publications
Lysosomal dysfunction in muscle with special reference to glycogen storage disease type IIReinout P Hesselink
Department of Movement Sciences, Cardiovascular Research Institute Maastricht, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
Biochim Biophys Acta 1637:164-70. 2003....
Age-related morphological changes in skeletal muscle cells of acid alpha-glucosidase knockout miceReinout P Hesselink
Department of Movement Sciences, Cardiovascular Research Institute Maastricht, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands
Muscle Nerve 33:505-13. 2006..These collective findings, on the one hand, may explain the decrease in tissue quality and, on the other, may represent markers for efficacy of therapeutic interventions to restore muscle function in patients suffering from GSDII...
Effects of non-contractile inclusions on mechanical performance of skeletal muscleMaarten R Drost
Department of Movement Sciences, Nutrition and Toxicology Research Institute Maastricht NUTRIM, Maastricht University, P O Box 616 NL 6200, MD Maastricht, The Netherlands
J Biomech 38:1035-43. 2005..As glycogen accumulation reaches higher levels in humans, it is highly probable that the impact of this mechanical interaction is even more severe in human skeletal muscle...
Age-related decline in muscle strength and power output in acid 1-4 alpha-glucosidase knockout miceReinout P Hesselink
Department of Movement Sciences, Nutrition and Toxicology Research Institute, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
Muscle Nerve 31:374-81. 2005..Mechanical effects of glycogen inclusions could not fully explain this decrease. Additional factors must therefore play a role...
Impaired performance of skeletal muscle in alpha-glucosidase knockout miceReinout P Hesselink
Department of Movement Sciences, Cardiovascular Research Institute, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
Muscle Nerve 25:873-83. 2002..The increase in muscular desmin content is most likely reflecting adaptations to altered intracellular force transmission...
A modified PAS stain combined with immunofluorescence for quantitative analyses of glycogen in muscle sectionsGert Schaart
Department of Movement Sciences, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands
Histochem Cell Biol 122:161-9. 2004..In conclusion, the novel protocol permits the combined use of PAS with immunofluorescence and shows valid conversion of data obtained by microdensitometry to genuine glycogen data...
