G R M M Haenen

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi request reprint The use of vitamin supplements in self-medication
    G R M M Haenen
    Department of Pharmacology and Toxicology, Faculty of Medicine, Maastricht University, POB 616, 6200 MD Maastricht, The Netherlands
    Therapie 57:119-22. 2002
  2. ncbi request reprint Analysis of oxidative DNA damage after human dietary supplementation with linoleic acid
    T M C M de Kok
    Department of Health Risk Analysis and Toxicology, University Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Food Chem Toxicol 41:351-8. 2003
  3. ncbi request reprint Lack of inhibition of endothelial nitric oxide synthase in the isolated rat aorta by doxorubicin
    G J M den Hartog
    Department of Pharmacology and Toxicology, University Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Toxicol In Vitro 17:165-7. 2003
  4. ncbi request reprint Oxidant metabolism in chronic obstructive pulmonary disease
    A W Boots
    Dept of Pharmacology and Toxicology, Faculty of Medicine, University of Maastricht, Maastricht, The Netherlands
    Eur Respir J Suppl 46:14s-27s. 2003
  5. ncbi request reprint Protectors against doxorubicin-induced cardiotoxicity: flavonoids
    A Bast
    Department of Pharmacology and Toxicology, Faculty of Medicine, Maastricht University, Maastricht, The Netherlands
    Cell Biol Toxicol 23:39-47. 2007
  6. ncbi request reprint The olive oil antioxidant hydroxytyrosol efficiently protects against the oxidative stress-induced impairment of the NObullet response of isolated rat aorta
    S J Rietjens
    Departments of 1Pharmacology and Toxicology, Faculty of Medicine, Maastricht University, Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 292:H1931-6. 2007
  7. ncbi request reprint The thiol reactivity of the oxidation product of 3,5,7-trihydroxy-4H-chromen-4-one containing flavonoids
    G Michels
    Institute of Toxicology, University of Dusseldorf, P O Box 101007, 4001 Duesseldorf, Germany
    Toxicol Lett 151:105-11. 2004

Collaborators

  • A Bast
  • H Kaiserova
  • Saskia J Rietjens
  • A W Boots
  • G Michels
  • G J M den Hartog
  • T M C M de Kok
  • W Watjen
  • J C S Kleinjans
  • E J Moonen
  • P A E L Schilderman
  • W J F van der Vijgh
  • E Rhijnsburger
  • I Zwingman

Detail Information

Publications7

  1. ncbi request reprint The use of vitamin supplements in self-medication
    G R M M Haenen
    Department of Pharmacology and Toxicology, Faculty of Medicine, Maastricht University, POB 616, 6200 MD Maastricht, The Netherlands
    Therapie 57:119-22. 2002
    ..Via diverse sources there is an uncontrolled supply of vitamins. Educating the consumer on vitamins is therefore the only way to come to a rational use of vitamin supplements in self medication...
  2. ncbi request reprint Analysis of oxidative DNA damage after human dietary supplementation with linoleic acid
    T M C M de Kok
    Department of Health Risk Analysis and Toxicology, University Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Food Chem Toxicol 41:351-8. 2003
    ..Therefore, we see no scientific basis to reconsider the public health policy to stimulate the intake of polyunsaturated fatty acids aimed at the reduction of coronary heart diseases...
  3. ncbi request reprint Lack of inhibition of endothelial nitric oxide synthase in the isolated rat aorta by doxorubicin
    G J M den Hartog
    Department of Pharmacology and Toxicology, University Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Toxicol In Vitro 17:165-7. 2003
    ..Direct measurement of nitrite, the metabolite of NO*, by the Griess assay confirmed our observation that NO*)production is not inhibited by doxorubicin...
  4. ncbi request reprint Oxidant metabolism in chronic obstructive pulmonary disease
    A W Boots
    Dept of Pharmacology and Toxicology, Faculty of Medicine, University of Maastricht, Maastricht, The Netherlands
    Eur Respir J Suppl 46:14s-27s. 2003
    ..A diet designed to reduce chronic metabolic stress might form an effective therapeutic strategy in chronic obstructive pulmonary disease...
  5. ncbi request reprint Protectors against doxorubicin-induced cardiotoxicity: flavonoids
    A Bast
    Department of Pharmacology and Toxicology, Faculty of Medicine, Maastricht University, Maastricht, The Netherlands
    Cell Biol Toxicol 23:39-47. 2007
    ..From a study in human volunteers, we conclude that an intravenous dose of 1500 mg/m(2) of 7-monohydroxyethylrutoside is feasible and is safe to be investigated as protection against doxorubicin-induced cardiotoxicity...
  6. ncbi request reprint The olive oil antioxidant hydroxytyrosol efficiently protects against the oxidative stress-induced impairment of the NObullet response of isolated rat aorta
    S J Rietjens
    Departments of 1Pharmacology and Toxicology, Faculty of Medicine, Maastricht University, Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 292:H1931-6. 2007
    ..The present study provides a molecular basis for the contribution of hydroxytyrosol to the benefits of the Mediterranean diet...
  7. ncbi request reprint The thiol reactivity of the oxidation product of 3,5,7-trihydroxy-4H-chromen-4-one containing flavonoids
    G Michels
    Institute of Toxicology, University of Dusseldorf, P O Box 101007, 4001 Duesseldorf, Germany
    Toxicol Lett 151:105-11. 2004
    ..This should be considered in application of these types of antioxidants...