Research Topics
| G R M M HaenenSummaryAffiliation: Maastricht University Country: The Netherlands Publications
| Collaborators
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Detail Information
Publications
The use of vitamin supplements in self-medicationG R M M Haenen
Department of Pharmacology and Toxicology, Faculty of Medicine, Maastricht University, POB 616, 6200 MD Maastricht, The Netherlands
Therapie 57:119-22. 2002..Via diverse sources there is an uncontrolled supply of vitamins. Educating the consumer on vitamins is therefore the only way to come to a rational use of vitamin supplements in self medication...
Analysis of oxidative DNA damage after human dietary supplementation with linoleic acidT M C M de Kok
Department of Health Risk Analysis and Toxicology, University Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
Food Chem Toxicol 41:351-8. 2003..Therefore, we see no scientific basis to reconsider the public health policy to stimulate the intake of polyunsaturated fatty acids aimed at the reduction of coronary heart diseases...
Lack of inhibition of endothelial nitric oxide synthase in the isolated rat aorta by doxorubicinG J M den Hartog
Department of Pharmacology and Toxicology, University Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
Toxicol In Vitro 17:165-7. 2003..Direct measurement of nitrite, the metabolite of NO*, by the Griess assay confirmed our observation that NO*)production is not inhibited by doxorubicin...
Oxidant metabolism in chronic obstructive pulmonary diseaseA W Boots
Dept of Pharmacology and Toxicology, Faculty of Medicine, University of Maastricht, Maastricht, The Netherlands
Eur Respir J Suppl 46:14s-27s. 2003..A diet designed to reduce chronic metabolic stress might form an effective therapeutic strategy in chronic obstructive pulmonary disease...
Protectors against doxorubicin-induced cardiotoxicity: flavonoidsA Bast
Department of Pharmacology and Toxicology, Faculty of Medicine, Maastricht University, Maastricht, The Netherlands
Cell Biol Toxicol 23:39-47. 2007..From a study in human volunteers, we conclude that an intravenous dose of 1500 mg/m(2) of 7-monohydroxyethylrutoside is feasible and is safe to be investigated as protection against doxorubicin-induced cardiotoxicity...
The olive oil antioxidant hydroxytyrosol efficiently protects against the oxidative stress-induced impairment of the NObullet response of isolated rat aortaS J Rietjens
Departments of 1Pharmacology and Toxicology, Faculty of Medicine, Maastricht University, Maastricht, The Netherlands
Am J Physiol Heart Circ Physiol 292:H1931-6. 2007..The present study provides a molecular basis for the contribution of hydroxytyrosol to the benefits of the Mediterranean diet...
The thiol reactivity of the oxidation product of 3,5,7-trihydroxy-4H-chromen-4-one containing flavonoidsG Michels
Institute of Toxicology, , P.O. Box 101007, 4001 Duesseldorf, Germany
Toxicol Lett 151:105-11. 2004..This should be considered in application of these types of antioxidants...
