Pieter J Emans

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi request reprint In vivo generation of cartilage from periosteum
    Pieter J Emans
    Department of Orthopedic Surgery, University Hospital Maastricht, The Netherlands
    Tissue Eng 11:369-77. 2005
  2. ncbi request reprint Differential cell viability of chondrocytes and progenitor cells in tissue-engineered constructs following implantation into osteochondral defects
    Pieter J Emans
    Department of Orthopedic Surgery, University Hospital Maastricht, The Netherlands
    Tissue Eng 12:1699-709. 2006
  3. ncbi request reprint The Currarino triad: neurosurgical considerations
    Pieter J Emans
    Department of Pediatric Surgery, University Hospital Maastricht, Maastricht, The Netherlands
    Neurosurgery 58:924-9; discussion 924-9. 2006
  4. doi request reprint Tissue-engineered constructs: the effect of scaffold architecture in osteochondral repair
    P J Emans
    Department of Orthopaedic Surgery, Maastricht University Medical Centre, The Netherlands
    J Tissue Eng Regen Med 7:751-6. 2013
  5. ncbi request reprint Results of total hip arthroplasties in the young patient; further evidence for a barrier against articular wear debris by hydroxyapatite coatings
    Pieter J Emans
    Department of Orthopaedic Surgery, Maastricht University Medical Centre, Maastricht The Netherlands
    Hip Int 19:343-51. 2009
  6. pmc Autologous engineering of cartilage
    Pieter J Emans
    Department of Orthopedic Surgery, Maastricht University Medical Centre, Maastricht, 6200 MD, Netherlands
    Proc Natl Acad Sci U S A 107:3418-23. 2010
  7. ncbi request reprint A novel in vivo model to study endochondral bone formation; HIF-1alpha activation and BMP expression
    Pieter J Emans
    Department of Orthopedic Surgery, University Hospital Maastricht, Maastricht, The Netherlands
    Bone 40:409-18. 2007
  8. doi request reprint Polypropylene meshes to prevent abdominal herniation. Can stable coatings prevent adhesions in the long term?
    Pieter J Emans
    Department of General Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands
    Ann Biomed Eng 37:410-8. 2009
  9. doi request reprint Human periosteum-derived cells from elderly patients as a source for cartilage tissue engineering?
    Edwin J P Jansen
    Department of Orthopaedic Surgery, University Hospital Maastricht, Maastricht, The Netherlands
    J Tissue Eng Regen Med 2:331-9. 2008
  10. doi request reprint Osmolarity determines the in vitro chondrogenic differentiation capacity of progenitor cells via nuclear factor of activated T-cells 5
    Marjolein M J Caron
    Department of Orthopaedic Surgery, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Center, P O Box 5800, 6202 AZ, Maastricht, The Netherlands
    Bone 53:94-102. 2013

Collaborators

Detail Information

Publications18

  1. ncbi request reprint In vivo generation of cartilage from periosteum
    Pieter J Emans
    Department of Orthopedic Surgery, University Hospital Maastricht, The Netherlands
    Tissue Eng 11:369-77. 2005
    ..Also, periosteal callus formation, providing possible useful information for tissue engineering techniques, can be studied with this model...
  2. ncbi request reprint Differential cell viability of chondrocytes and progenitor cells in tissue-engineered constructs following implantation into osteochondral defects
    Pieter J Emans
    Department of Orthopedic Surgery, University Hospital Maastricht, The Netherlands
    Tissue Eng 12:1699-709. 2006
    ..Although we did not test progenitor cells other the periosteum cells, tissue-engineering approaches using such cell types should take cell viability aspects into consideration...
  3. ncbi request reprint The Currarino triad: neurosurgical considerations
    Pieter J Emans
    Department of Pediatric Surgery, University Hospital Maastricht, Maastricht, The Netherlands
    Neurosurgery 58:924-9; discussion 924-9. 2006
    ..The objective of this study is to identify the spinal cord and meningeal malformations associated with the Currarino triad and to discuss the risks and benefits of surgical intervention...
  4. doi request reprint Tissue-engineered constructs: the effect of scaffold architecture in osteochondral repair
    P J Emans
    Department of Orthopaedic Surgery, Maastricht University Medical Centre, The Netherlands
    J Tissue Eng Regen Med 7:751-6. 2013
    ..It is concluded that scaffold pore size and pore interconnectivity influences osteochondral repair and a decreased pore interconnectivity seems to impair osteochondral repair...
  5. ncbi request reprint Results of total hip arthroplasties in the young patient; further evidence for a barrier against articular wear debris by hydroxyapatite coatings
    Pieter J Emans
    Department of Orthopaedic Surgery, Maastricht University Medical Centre, Maastricht The Netherlands
    Hip Int 19:343-51. 2009
    ..The use of cups with a backside gap resulted in PE-wear associated osteolysis in cup zone II and may be considered to be best avoided...
  6. pmc Autologous engineering of cartilage
    Pieter J Emans
    Department of Orthopedic Surgery, Maastricht University Medical Centre, Maastricht, 6200 MD, Netherlands
    Proc Natl Acad Sci U S A 107:3418-23. 2010
    ..An "on demand" autologous source of autologous cartilage with remodeling capacity is expected to significantly impact the clinical options in repair of trauma to articular cartilage...
  7. ncbi request reprint A novel in vivo model to study endochondral bone formation; HIF-1alpha activation and BMP expression
    Pieter J Emans
    Department of Orthopedic Surgery, University Hospital Maastricht, Maastricht, The Netherlands
    Bone 40:409-18. 2007
    ..Our model recapitulates essential steps in osteochondrogenesis and provides a new experimental system to study and ultimately control tissue regeneration in the adult organism...
  8. doi request reprint Polypropylene meshes to prevent abdominal herniation. Can stable coatings prevent adhesions in the long term?
    Pieter J Emans
    Department of General Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands
    Ann Biomed Eng 37:410-8. 2009
    ..The data indicate that long-term protection of implanted meshes against excessive adhesions may be achieved through stable biocompatible hydrogel surface coatings...
  9. doi request reprint Human periosteum-derived cells from elderly patients as a source for cartilage tissue engineering?
    Edwin J P Jansen
    Department of Orthopaedic Surgery, University Hospital Maastricht, Maastricht, The Netherlands
    J Tissue Eng Regen Med 2:331-9. 2008
    ..By expanding cells in MEM-DV, the selection of progenitor cells might be favoured, which would result in a higher cartilage yield for tissue engineering applications...
  10. doi request reprint Osmolarity determines the in vitro chondrogenic differentiation capacity of progenitor cells via nuclear factor of activated T-cells 5
    Marjolein M J Caron
    Department of Orthopaedic Surgery, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Center, P O Box 5800, 6202 AZ, Maastricht, The Netherlands
    Bone 53:94-102. 2013
    ..The effects of increased osmolarity on chondrogenesis of progenitor cells in vitro are largely unknown. We therefore aimed to elucidate whether hyperosmolarity facilitates their chondrogenic differentiation and whether Nfat5 is involved...
  11. pmc Activation of NF-κB/p65 facilitates early chondrogenic differentiation during endochondral ossification
    Marjolein M J Caron
    Department of Orthopaedic Surgery, CAPHRI School for Public Health and Primary Care, Maastricht University Medical Center, Maastricht, The Netherlands
    PLoS ONE 7:e33467. 2012
    ..We hypothesized that the early onset of chondrogenic differentiation is initiated by transient NF-κB/p65 signaling...
  12. ncbi request reprint Repair of osteochondral defects in rabbits with ectopically produced cartilage
    Pieter J Emans
    Department of Orthopedic Surgery, University Hospital Maastricht, Maastricht, The Netherlands
    Tissue Eng 11:1789-96. 2005
    ..3 +/- 3.2; for treated defects scores were better (15.4 +/- 3.9 and 18.2 +/- 2.9). In this conceptual study the use of ectopic cartilage derived from periosteum appears to be a promising novel method for joint surface repair in rabbits...
  13. pmc Development of partial-thickness articular cartilage injury in a rabbit model
    Edwin J Jansen
    Department of Orthopedic Surgery, University Hospital of Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Clin Orthop Relat Res 466:487-94. 2008
    ..Disturbances in proteoglycan metabolism were less evident. In this rabbit model, a partial-thickness cartilage lesion resulted in early markers of degenerative changes resembling the human situation...
  14. doi request reprint One intra-articular injection of hyaluronan prevents cell death and improves cell metabolism in a model of injured articular cartilage in the rabbit
    Edwin J P Jansen
    Department of Orthopaedic Surgery, University Hospital of Maastricht, Maastricht, The Netherlands
    J Orthop Res 26:624-30. 2008
    ..9% NaCl. These results suggest a potential role for hyaluronan in preventing cell death following articular cartilage injury. One injection of hyaluronan improved cartilage metabolism in knees with 6-month-old cartilage defects...
  15. ncbi request reprint The Currarino triad: the variable expression
    Pieter J Emans
    Department of Pediatric Surgery, University Hospital, 6202 AZ Maastricht, The Netherlands
    J Pediatr Surg 40:1238-42. 2005
    ..The Currarino triad is a relatively unknown hereditary disorder linked to the 7q36 region and characterized by an anorectal malformation, sacrococcygeal defect, and a presacral mass...
  16. ncbi request reprint Comparison of two hydroxyapatite-coated femoral stems: clinical, functional, and bone densitometry evaluation of patients randomized to a regular or modified hydroxyapatite-coated stem aimed at proximal fixation
    Judith C Sluimer
    Orthopaedics Department, University Hospital Maastricht, Maastricht, The Netherlands
    J Arthroplasty 21:344-52. 2006
    ..No strong correlations between clinical function and radiographic evaluation of remodeling were found with BMD, suggesting that dual-energy x-ray absorptiometry has no predictive value for short-term clinical outcome...
  17. doi request reprint Randomized comparison between the cemented scientific hip prosthesis and Omnifit: 2-year DEXA and minimum 10-year clinical follow-up
    Rene H M Ten Broeke
    Department of Orthopaedic Surgery, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands
    J Arthroplasty 28:1354-61. 2013
    ..However our clinical and remodelling results could not confirm these expectations, suggesting that the link of early migration and mid-term clinical results is not sufficiently clear for the SHP...
  18. ncbi request reprint Assessing infection risk in implanted tissue-engineered devices
    Roel Kuijer
    Department of Biomedical Engineering, University Medical Center Groningen, University of Groningen, P O Box 196, 9700 AD Groningen, The Netherlands
    Biomaterials 28:5148-54. 2007
    ..Infection control measures should be developed in tissue engineering to avoid further complications when TE devices emerge clinically...