S L M Coort

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi request reprint Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese zucker rats
    Susan L M Coort
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, P O Box 616, NL 6200 Maastricht, Netherlands
    Diabetes 53:1655-63. 2004
  2. ncbi request reprint Divergent effects of rosiglitazone on protein-mediated fatty acid uptake in adipose and in muscle tissues of Zucker rats
    S L M Coort
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    J Lipid Res 46:1295-302. 2005
  3. ncbi request reprint Increased FAT (fatty acid translocase)/CD36-mediated long-chain fatty acid uptake in cardiac myocytes from obese Zucker rats
    S L M Coort
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, P O Box 616, NL 6200 MD Maastricht, The Netherlands
    Biochem Soc Trans 32:83-5. 2004
  4. pmc Effects of cAMP modulators on long-chain fatty-acid uptake and utilization by electrically stimulated rat cardiac myocytes
    J J F P Luiken
    Department of Physiology, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, NL 6200 MD Maastricht, The Netherlands
    Biochem J 367:881-7. 2002
  5. ncbi request reprint Uncoupling protein 3 as a mitochondrial fatty acid anion exporter
    Patrick Schrauwen
    Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, The Netherlands
    FASEB J 17:2272-4. 2003
  6. pmc Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: role of sarcolemmal substrate transporters
    Susan L M Coort
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands
    Mol Cell Biochem 299:5-18. 2007
  7. ncbi request reprint Prolonged AMPK activation increases the expression of fatty acid transporters in cardiac myocytes and perfused hearts
    Adrian Chabowski
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    Mol Cell Biochem 288:201-12. 2006
  8. ncbi request reprint The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR
    Adrian Chabowski
    Department of Human Biology and Nutritional Sciences, University of Guelph, Ont, Canada
    FEBS Lett 579:2428-32. 2005
  9. ncbi request reprint Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake
    Susan L M Coort
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Mol Cell Biochem 239:213-9. 2002
  10. ncbi request reprint Signalling components involved in contraction-inducible substrate uptake into cardiac myocytes
    Joost J F P Luiken
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, NL 6200 MD Maastricht, The Netherlands
    Proc Nutr Soc 63:251-8. 2004

Detail Information

Publications16

  1. ncbi request reprint Enhanced sarcolemmal FAT/CD36 content and triacylglycerol storage in cardiac myocytes from obese zucker rats
    Susan L M Coort
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, P O Box 616, NL 6200 Maastricht, Netherlands
    Diabetes 53:1655-63. 2004
    ....
  2. ncbi request reprint Divergent effects of rosiglitazone on protein-mediated fatty acid uptake in adipose and in muscle tissues of Zucker rats
    S L M Coort
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    J Lipid Res 46:1295-302. 2005
    ..In conclusion, our study implicates FAT/CD36 in the mechanism by which Rgz increases tissue insulin sensitivity...
  3. ncbi request reprint Increased FAT (fatty acid translocase)/CD36-mediated long-chain fatty acid uptake in cardiac myocytes from obese Zucker rats
    S L M Coort
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, P O Box 616, NL 6200 MD Maastricht, The Netherlands
    Biochem Soc Trans 32:83-5. 2004
    ....
  4. pmc Effects of cAMP modulators on long-chain fatty-acid uptake and utilization by electrically stimulated rat cardiac myocytes
    J J F P Luiken
    Department of Physiology, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, NL 6200 MD Maastricht, The Netherlands
    Biochem J 367:881-7. 2002
    ..The stimulatory effects of PDE inhibitors on cardiac FA uptake should be considered when applying these agents in clinical medicine...
  5. ncbi request reprint Uncoupling protein 3 as a mitochondrial fatty acid anion exporter
    Patrick Schrauwen
    Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, The Netherlands
    FASEB J 17:2272-4. 2003
    ..These data are compatible with a physiological function of UCP3 in facilitating outward transport of long-chain fatty acid anions, which cannot be oxidized, from the mitochondrial matrix...
  6. pmc Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: role of sarcolemmal substrate transporters
    Susan L M Coort
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands
    Mol Cell Biochem 299:5-18. 2007
    ..These novel insights may result in new strategies for the prevention of development of cardiac dysfunction and insulin resistance in obesity and T2DM...
  7. ncbi request reprint Prolonged AMPK activation increases the expression of fatty acid transporters in cardiac myocytes and perfused hearts
    Adrian Chabowski
    Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    Mol Cell Biochem 288:201-12. 2006
    ..Thus, activation of AMPK is a key mechanism regulating the expression as well as the plasmalemmal localization of fatty acid transporters...
  8. ncbi request reprint The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR
    Adrian Chabowski
    Department of Human Biology and Nutritional Sciences, University of Guelph, Ont, Canada
    FEBS Lett 579:2428-32. 2005
    ....
  9. ncbi request reprint Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake
    Susan L M Coort
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Mol Cell Biochem 239:213-9. 2002
    ....
  10. ncbi request reprint Signalling components involved in contraction-inducible substrate uptake into cardiac myocytes
    Joost J F P Luiken
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, NL 6200 MD Maastricht, The Netherlands
    Proc Nutr Soc 63:251-8. 2004
    ..The unravelling of further components along this contraction pathway can provide valuable information on the coordinated regulation of the uptake of glucose and of LCFA by an increase in mechanical activity of heart and skeletal muscle...
  11. ncbi request reprint Regulation of fatty acid transport by fatty acid translocase/CD36
    Arend Bonen
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Proc Nutr Soc 63:245-9. 2004
    ..Clearly, FAT/CD36 has an important role in FA homeostasis in skeletal muscle and the heart...
  12. ncbi request reprint Contraction-induced fatty acid translocase/CD36 translocation in rat cardiac myocytes is mediated through AMP-activated protein kinase signaling
    Joost J F P Luiken
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Diabetes 52:1627-34. 2003
    ..We conclude that AMP kinase regulates cardiac FA use through mobilization of FAT/CD36 from a contraction-inducible intracellular storage compartment...
  13. ncbi request reprint Insulin stimulates fatty acid transport by regulating expression of FAT/CD36 but not FABPpm
    Adrian Chabowski
    Department of Human Biology and Nutritional Sciences, University of Guelph, ON N1G 2W1, Canada
    Am J Physiol Endocrinol Metab 287:E781-9. 2004
    ..The present studies have shown that insulin regulates protein expression of FAT/CD36, but not FABPpm, via the PI 3-kinase/Akt insulin-signaling pathway...
  14. ncbi request reprint Dipyridamole alters cardiac substrate preference by inducing translocation of FAT/CD36, but not that of GLUT4
    Joost J F P Luiken
    Department of Molecular Genetics, CARIM, Maastricht University, Maastricht, The Netherlands
    Mol Pharmacol 65:639-45. 2004
    ....
  15. ncbi request reprint Regulation of cardiac long-chain fatty acid and glucose uptake by translocation of substrate transporters
    Joost J F P Luiken
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Pflugers Arch 448:1-15. 2004
    ..In the latter case, a unique set of proteins would be dedicated to FAT/CD36 recycling, which would then provide an attractive target for manipulating cardiac substrate preference...
  16. doi request reprint Identification of protein kinase D as a novel contraction-activated kinase linked to GLUT4-mediated glucose uptake, independent of AMPK
    Joost J F P Luiken
    Department of Molecular Genetics, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands
    Cell Signal 20:543-56. 2008
    ....