Maurits Allessie

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi Electrical, contractile and structural remodeling during atrial fibrillation
    Maurits Allessie
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, P O Box 616, 6200 MD Maastricht, The Netherlands
    Cardiovasc Res 54:230-46. 2002
  2. ncbi Blockade of atrial-specific K+-currents increases atrial but not ventricular contractility by enhancing reverse mode Na+/Ca2+-exchange
    Ulrich Schotten
    Department of Physiology, University Maastricht, The Netherlands
    Cardiovasc Res 73:37-47. 2007
  3. ncbi AVE0118, blocker of the transient outward current (I(to)) and ultrarapid delayed rectifier current (I(Kur)), fully restores atrial contractility after cardioversion of atrial fibrillation in the goat
    Sunniva de Haan
    Department of Physiology, University of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Circulation 114:1234-42. 2006
  4. ncbi Chronic atrial dilation, electrical remodeling, and atrial fibrillation in the goat
    Hans-Ruprecht Neuberger
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    J Am Coll Cardiol 47:644-53. 2006
  5. ncbi Loss of atrial contractility is primary cause of atrial dilatation during first days of atrial fibrillation
    Ulrich Schotten
    Dept of Physiology, Univ of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 287:H2324-31. 2004
  6. ncbi Electrical and contractile remodeling during the first days of atrial fibrillation go hand in hand
    Ulrich Schotten
    Department of Physiology, University of Maastricht, The Netherlands
    Circulation 107:1433-9. 2003
  7. ncbi Mechanisms of perpetuation of atrial fibrillation in chronically dilated atria
    Jens Eckstein
    Department of Physiology, Cardiovascular Research Institute, University Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Prog Biophys Mol Biol 97:435-51. 2008
  8. ncbi Development of a substrate of atrial fibrillation during chronic atrioventricular block in the goat
    Hans-Ruprecht Neuberger
    Department of Physiology, University of Maastricht, The Netherlands
    Circulation 111:30-7. 2005
  9. ncbi Long-term changes in sequence of atrial activation and refractory periods: no evidence for "atrial memory"
    Dirk Vollmann
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, The Netherlands
    Heart Rhythm 2:155-61. 2005
  10. ncbi Is there an optimal pacing site to prevent atrial fibrillation?: an experimental study in the chronically instrumented goat
    Mattias Duytschaever
    Department of Physiology, Maastricht University, Maastricht, The Netherlands
    J Cardiovasc Electrophysiol 13:1264-71. 2002

Collaborators

Detail Information

Publications19

  1. ncbi Electrical, contractile and structural remodeling during atrial fibrillation
    Maurits Allessie
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, P O Box 616, 6200 MD Maastricht, The Netherlands
    Cardiovasc Res 54:230-46. 2002
    ..New strategies for prevention and termination of AF should be build on our knowledge of the mechanisms and time course of AF-induced atrial remodeling...
  2. ncbi Blockade of atrial-specific K+-currents increases atrial but not ventricular contractility by enhancing reverse mode Na+/Ca2+-exchange
    Ulrich Schotten
    Department of Physiology, University Maastricht, The Netherlands
    Cardiovasc Res 73:37-47. 2007
    ..This study was designed to evaluate the inotropic mechanisms of AVE0118...
  3. ncbi AVE0118, blocker of the transient outward current (I(to)) and ultrarapid delayed rectifier current (I(Kur)), fully restores atrial contractility after cardioversion of atrial fibrillation in the goat
    Sunniva de Haan
    Department of Physiology, University of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Circulation 114:1234-42. 2006
    ..In contrast, the I(to)/I(Kur) blocker AVE0118 fully restored atrial contraction without proarrhythmic effects on the ventricle...
  4. ncbi Chronic atrial dilation, electrical remodeling, and atrial fibrillation in the goat
    Hans-Ruprecht Neuberger
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    J Am Coll Cardiol 47:644-53. 2006
    ..Thus, in dilated atria a wider excitable gap exists during AF, probably caused by intra-atrial conduction defects and a higher contribution of anatomically defined re-entrant circuits...
  5. ncbi Loss of atrial contractility is primary cause of atrial dilatation during first days of atrial fibrillation
    Ulrich Schotten
    Dept of Physiology, Univ of Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 287:H2324-31. 2004
    ..Atrial compliance and size are restored when atrial contractility recovers after cardioversion of AF...
  6. ncbi Electrical and contractile remodeling during the first days of atrial fibrillation go hand in hand
    Ulrich Schotten
    Department of Physiology, University of Maastricht, The Netherlands
    Circulation 107:1433-9. 2003
    ..The mechanisms of the atrial contractile dysfunction induced by atrial fibrillation (AF) are not completely understood. In particular, the relation between the atrial dysfunction and electrical remodeling has not yet been studied...
  7. ncbi Mechanisms of perpetuation of atrial fibrillation in chronically dilated atria
    Jens Eckstein
    Department of Physiology, Cardiovascular Research Institute, University Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands
    Prog Biophys Mol Biol 97:435-51. 2008
    ..This article reviews data suggesting a role of endo-epicardial dissociation in dilated and fibrillating atria, for the self-perpetuating nature of AF as well as its possible implications for therapeutic interventions...
  8. ncbi Development of a substrate of atrial fibrillation during chronic atrioventricular block in the goat
    Hans-Ruprecht Neuberger
    Department of Physiology, University of Maastricht, The Netherlands
    Circulation 111:30-7. 2005
    ..The increase in AF stability was not a result of a shortening of atrial refractoriness or atrial fibrosis...
  9. ncbi Long-term changes in sequence of atrial activation and refractory periods: no evidence for "atrial memory"
    Dirk Vollmann
    Department of Physiology, Cardiovascular Research Institute Maastricht, University of Maastricht, The Netherlands
    Heart Rhythm 2:155-61. 2005
    ..The purpose of this study was to test whether the spatial distribution of the atrial refractory period (AERP) and the vulnerability to atrial fibrillation (AF) are altered by long-term changes in the sequence of atrial activation...
  10. ncbi Is there an optimal pacing site to prevent atrial fibrillation?: an experimental study in the chronically instrumented goat
    Mattias Duytschaever
    Department of Physiology, Maastricht University, Maastricht, The Netherlands
    J Cardiovasc Electrophysiol 13:1264-71. 2002
    ..Atrial pacing can reduce the number of recurrences of atrial fibrillation (AF). It is unclear the extent to which this effect is determined by the site(s) of pacing...
  11. ncbi Fibrillatory conduction in the atrial free walls of goats in persistent and permanent atrial fibrillation
    Sander Verheule
    Department of Physiology, Faculty of Medicine, Maastricht University, Maastrict, The Netherlands
    Circ Arrhythm Electrophysiol 3:590-9. 2010
    ..Changes in fibrillatory conduction over this period largely are unexplored...
  12. ncbi Time course and mechanisms of endo-epicardial electrical dissociation during atrial fibrillation in the goat
    Jens Eckstein
    Department of Physiology, Maastricht University, Maastricht, The Netherlands
    Cardiovasc Res 89:816-24. 2011
    ....
  13. ncbi Supervulnerable phase immediately after termination of atrial fibrillation
    Mattias Duytschaever
    Department of Physiology, Maastricht University, The Netherlands
    J Cardiovasc Electrophysiol 13:267-75. 2002
    ..1 cm). These observations imply a highly vulnerable substrate for reentry immediately after termination of AF. During this supervulnerable phase, both early and later premature beats reinitiated immediate recurrences of AF...
  14. ncbi Atrial fibrillation-induced atrial contractile dysfunction: a tachycardiomyopathy of a different sort
    Ulrich Schotten
    Department of Physiology, University Maastricht, P O Box 616, 6200 MD Maastricht, The Netherlands
    Cardiovasc Res 53:192-201. 2002
    ..Although AF-induced atrial contractile dysfunction has significant clinical implications the underlying intracellular mechanisms are poorly understood...
  15. ncbi Limited benefit of septal pre-excitation in pace prevention of atrial fibrillation
    Mattias Duytschaever
    Department of Cardiology, University Hospital Ghent, Ghent, Belgium
    J Cardiovasc Electrophysiol 16:269-77. 2005
    ..AF vulnerability was compared to pacing at the right atrium (RA) and sinus rhythm (SR)...
  16. ncbi Polymorphic reentrant ventricular tachycardia in the isolated rabbit heart studied by high-density mapping
    Lucas Boersma
    Physiology Department, Maastricht University, Maastricht, The Netherlands
    Circulation 105:3053-61. 2002
    ..CONCLUSIONS: A shifting functional reentrant circuit was the underlying mechanism of polymorphic VT in a substrate of enhanced spatial heterogeneity of refractoriness...
  17. ncbi Gene therapy for repair of cardiac fibrosis: a long way to Tipperary
    Maurits Allessie
    Circulation 111:391-3. 2005
  18. ncbi Paroxysmal atrial fibrillation: just a matter of nerves?
    Maurits Allessie
    Heart Rhythm 3:209-11. 2006
  19. ncbi Spotlight on atrial fibrillation-the 'complete arrhythmia'
    Stanley Nattel
    Cardiovasc Res 54:197-203. 2002