Research Topics
Genomes and GenesSpecies | Hans G LemijSummaryCountry: The Netherlands Publications
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Detail Information
Publications
Retinal nerve fiber layer measurement repeatability in scanning laser polarimetry with enhanced corneal compensationThê Anh Mai
The Rotterdam Eye Hospital, Rotterdam, The Netherlands
J Glaucoma 17:269-74. 2008....
The value of polarimetry in the evaluation of the optic nerve in glaucomaH G Lemij
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Curr Opin Ophthalmol 12:138-42. 2001..If well compensated in all, SLP may better separate diseased from normal eyes. Its promising role in the follow-up of glaucoma is still under investigation...- New developments in scanning laser polarimetry for glaucomaHans G Lemij
Glaucoma Service, Rotterdam Eye Hospital, Rotterdam, The Netherlands
Curr Opin Ophthalmol 19:136-40. 2008..This review summarizes recent advances made to reduce the frequency and severity of these patterns. In addition, recent progress in the development of algorithms for detecting progression is discussed... - Clinical implications of old and new genes for open-angle glaucomaWishal D Ramdas
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
Ophthalmology 118:2389-97. 2011..This study was performed to determine to what extent variants within established genes (MYOC, OPTN, and WDR36) and newly identified common genetic variants (ATOH7, CDKN2B, and SIX1) contribute to the risk of OAG... - Enhanced imaging algorithm for scanning laser polarimetry with variable corneal compensationNicolaas J Reus
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Invest Ophthalmol Vis Sci 47:3870-7. 2006..To describe and investigate a method of improving assessment of retinal nerve fiber layer (RNFL) morphology with scanning laser polarimetry (SLP) with variable corneal compensation (VCC)... - The ability of short-wavelength automated perimetry to predict conversion to glaucomaJosine van der Schoot
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Ophthalmology 117:30-4. 2010..This study compared the moment of glaucomatous conversion between SWAP and SAP... - Structure-function relationship is stronger with enhanced corneal compensation than with variable corneal compensation in scanning laser polarimetryThê Anh Mai
The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Invest Ophthalmol Vis Sci 48:1651-8. 2007..Dublin, CA), and visual field (VF) sensitivity, measured with standard automated perimetry (SAP) in normal and glaucomatous eyes and the effect of marked atypical birefringence patterns (ABPs) on this relationship... - Relationships between standard automated perimetry, HRT confocal scanning laser ophthalmoscopy, and GDx VCC scanning laser polarimetryNicolaas J Reus
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Invest Ophthalmol Vis Sci 46:4182-8. 2005.... - Scanning laser polarimetry of the retinal nerve fiber layer in perimetrically unaffected eyes of glaucoma patientsNicolaas J Reus
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Ophthalmology 111:2199-203. 2004..To compare scanning laser polarimetry (SLP) measurements of retinal nerve fiber layer (RNFL) thickness in perimetrically unaffected eyes of glaucoma patients with those in their fellow eyes with field loss and eyes of healthy subjects... - A genetic epidemiologic study of candidate genes involved in the optic nerve head morphologyAndrea C Gasten
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
Invest Ophthalmol Vis Sci 53:1485-91. 2012..The purpose of the present study was to investigate whether genes encoding protein known to interact with protein encoded by SALL1 and SIX1 are also associated with either DA or VCDR... - Diagnostic accuracy of the GDx VCC for glaucomaNicolaas J Reus
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Ophthalmology 111:1860-5. 2004..To determine the diagnostic accuracy of the GDx VCC in the diagnosis of glaucoma... - Visualization of localized retinal nerve fiber layer defects with the GDx with individualized and with fixed compensation of anterior segment birefringenceNicolaas J Reus
The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Ophthalmology 110:1512-6. 2003..With FC, however, the GDx retardation images did not correlate well with red-free fundus photography. CONCLUSIONS: An individualized anterior segment compensation in the GDx improves the visualization of localized glaucomatous loss... - Clinical assessment of stereoscopic optic disc photographs for glaucoma: the European Optic Disc Assessment TrialNicolaas J Reus
Glaucoma Service, Rotterdam Eye Hospital, Rotterdam, The Netherlands
Ophthalmology 117:717-23. 2010..To determine the diagnostic accuracy of judging optic disc photographs for glaucoma by ophthalmologists... - Sensitivity and specificity of the GDx: clinical judgment of standard printouts versus the numberThomas P Colen
Glaucoma Service, The Rotterdam Eye Hospital, The Netherlands
J Glaucoma 12:129-33. 2003..The authors evaluated the sensitivity and specificity of the Number and examined whether expert clinical judgment of GDx printouts leads to a better separation... - Common genetic variants associated with open-angle glaucomaWishal D Ramdas
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
Hum Mol Genet 20:2464-71. 2011..These findings may shed new light on the pathophysiological protein pathways leading to glaucoma, and point to pathways involved in the growth and development of the optic nerve... 
Common genetic determinants of intraocular pressure and primary open-angle glaucomaLeonieke M E van Koolwijk
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
PLoS Genet 8:e1002611. 2012..Both genes functionally interact with known glaucoma disease genes. These data suggest that we have identified two clinically relevant genes involved in IOP regulation...- Cost-effectiveness of monitoring glaucoma patients in shared care: an economic evaluation alongside a randomized controlled trialKim M Holtzer-Goor
Institute for Medical Technology Assessment Erasmus University Rotterdam, Rotterdam, The Netherlands
BMC Health Serv Res 10:312. 2010..Because quality of care turned out to be similar, we focus here on the costs... - The relationship between standard automated perimetry and GDx VCC measurementsNicolaas J Reus
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Invest Ophthalmol Vis Sci 45:840-5. 2004..San Diego, CA)... - Genetic architecture of open angle glaucoma and related determinantsWishal D Ramdas
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
J Med Genet 48:190-6. 2011..We evaluated whether the same genes that determine VCDR and IOP also predict OAG... - Motion artifacts in scanning laser polarimetryThomas P Colen
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Ophthalmology 109:1568-72. 2002..The aims of this study were to investigate the effect of motion artifacts on the retardation values and to illustrate how motion artifacts can be identified... - Association of cognitive functioning with retinal nerve fiber layer thicknessLeonieke M E van Koolwijk
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Invest Ophthalmol Vis Sci 50:4576-80. 2009..The association between cognitive functioning and retinal nerve fiber layer (RNFL) thickness was assessed in a large, population-based sample... - Effects of inadequate anterior segment compensation on measurements with scanning laser polarimetryNicolaas J Reus
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Ophthalmic Surg Lasers Imaging 37:54-7. 2006..Knowledge of this effect is important for clinicians when using scanning laser polarimetry in clinical practice... - The prevalence of glaucomatous defects with short-wavelength automated perimetry in patients with elevated intraocular pressuresNicolaas J Reus
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
J Glaucoma 14:26-9. 2005.... - Accuracy of GDx VCC, HRT I, and clinical assessment of stereoscopic optic nerve head photographs for diagnosing glaucomaNicolaas J Reus
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Br J Ophthalmol 91:313-8. 2007.... - Sensitivity and specificity of new GDx parametersThomas P Colen
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
J Glaucoma 13:28-33. 2004..The aim of this study was to investigate the sensitivity and specificity of these four new parameters... - Why a successful task substitution in glaucoma care could not be transferred from a hospital setting to a primary care setting: a qualitative studyKim M Holtzer-Goor
Institute for Health Policy and Management, Erasmus University Rotterdam, Rotterdam, The Netherlands
Implement Sci 8:14. 2013..Our study aimed to explore stakeholders' perceived feasibility of transferring hospital-based monitoring of stable glaucoma patients to primary care optometrists... - RPE-normalized RNFL attenuation coefficient maps derived from volumetric OCT imaging for glaucoma assessmentKoenraad A Vermeer
Rotterdam Ophthalmic Institute, Rotterdam Eye Hospital, Rotterdam, The Netherlands
Invest Ophthalmol Vis Sci 53:6102-8. 2012..Quantitative analyses of differences between healthy and glaucomatous eyes were performed... - Genetic contributions to glaucoma: heritability of intraocular pressure, retinal nerve fiber layer thickness, and optic disc morphologyLeonieke M E van Koolwijk
Glaucoma Service, The Rotterdam Eye Hospital, Rotterdam, The Netherlands
Invest Ophthalmol Vis Sci 48:3669-76. 2007.... - Improving the quality of eye care with tele-ophthalmology: shared-care glaucoma screeningMarleen de Mul
Department of Health Policy and Management, Erasmus Medical Centre, Rotterdam, The Netherlands
J Telemed Telecare 10:331-6. 2004..Task redesign was needed to transfer screening from the hospital to primary care in a safe and responsible way. Telemedicine was crucial for assuring quality, facilitating information exchange and for coordination... - Modeling of scanning laser polarimetry images of the human retina for progression detection of glaucomaKoen A Vermeer
Glaucoma Service, Rotterdam Eye Hospital, Schiedamsevest 180, NL 3011 BH Rotterdam, The Netherlands
IEEE Trans Med Imaging 25:517-28. 2006..The results show that detecting progression based on two follow-up visits greatly improves the sensitivity without adversely affecting the specificity... - Creating patient value in glaucoma care: applying quality costing and care delivery value chain approaches--a five-year case study in the Rotterdam Eye HospitalDirk F de Korne
Institute of Health Policy and Management, Erasmus University, Rotterdam, The Netherlands
Int J Health Care Qual Assur 22:232-51. 2009..The purpose of this paper is to explore in a specific hospital care process the applicability in practice of the theories of quality costing and value chains... - A genome-wide association study of optic disc parametersWishal D Ramdas
Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
PLoS Genet 6:e1000978. 2010..Three of the loci were marginally associated with open-angle glaucoma. The protein pathways in which the loci of optic disc area are involved overlap with those identified for VCDR, suggesting a common genetic origin... - Variable corneal compensation improves discrimination between normal and glaucomatous eyes with the scanning laser polarimeterDana P Tannenbaum
Jules Stein Eye Institute, UCLA School of Medicine, Los Angeles, California 90095, USA
Ophthalmology 111:259-64. 2004..The aim of this study was to evaluate the relative ability of the SLP with the FCC and with the VCC to discriminate between normal and glaucomatous eyes... - Clinician change detection viewing longitudinal stereophotographs compared to confocal scanning laser tomography in the LSU Experimental Glaucoma (LEG) StudyJohn C Ervin
LSU Eye Center, Louisiana State University Health Sciences Center, 2020 Gravier Street, Suite B, New Orleans, LA 70112, USA
Ophthalmology 109:467-81. 2002.... - Longitudinal measurement variability of corneal birefringence and retinal nerve fiber layer thickness in scanning laser polarimetry with variable corneal compensationThê Anh Mai
Department of Ophthalmology, University Medical Center Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands
Arch Ophthalmol 126:1359-64. 2008..We also calculated the percentage of these values within the range of +/-5 degrees or +/-5 nm, respectively. Any effect of corneal birefringence variability on the retinal nerve fiber layer measurements was also evaluated...