- Antisense-mediated isoform switching of steroid receptor coactivator-1 in the central nucleus of the amygdala of the mouse brainIoannis Zalachoras
Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden University Leiden University Medical Center, Leiden, The Netherlands
BMC Neurosci 14:5. 2013..This nuclear receptor coregulator exists in two splice variants (SRC-1a and SRC-1e) which display differential distribution and opposing activities in the brain, and whose mRNAs differ in a single SRC-1e specific exon...
- Understanding stress-effects in the brain via transcriptional signal transduction pathwaysI Zalachoras
Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands
Neuroscience 242:97-109. 2013..Finally, we discuss the potential of selective receptor modulators that may only allow a subset of all interactions, thus allowing more selective targeting of glucocorticoid-dependent processes in the brain...