Detail Information
Publications
Kinome profiling of myxoid liposarcoma reveals NF-kappaB-pathway kinase activity and casein kinase II inhibition as a potential treatment optionStefan M Willems
Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
Mol Cancer 9:257. 2010..Treatment options in patients with inoperable or metastatic myxoid liposarcoma are relatively poor though being developed and new hope is growing...
Local recurrence of myxofibrosarcoma is associated with increase in tumour grade and cytogenetic aberrations, suggesting a multistep tumour progression modelStefan M Willems
Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
Mod Pathol 19:407-16. 2006..Based on these findings, we suggest that tumorigenesis of myxofibrosarcoma is mainly a multistep genetic process, probably ruled by genetic instability caused by targeted checkpoint genes...
Macroscopic hematuria in patient with myelofibrosis caused by extramedullary hematopoiesis of bladderStefan Martin Willems
Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
Urology 72:948.e13-4. 2008..EMH in the bladder is extremely rare but illustrates the importance of an adequate pathologic assessment of transurethral resection chips, especially in patients with underlying disease...
