J P Vandenbroucke

Summary

Affiliation: Leiden University
Country: The Netherlands

Publications

  1. ncbi Changing images of John Snow in the history of epidemiology
    J P Vandenbroucke
    Leiden University Medical Center
    Soz Praventivmed 46:288-93. 2001
  2. ncbi Alternative medicine: a "mirror image" for scientific reasoning in conventional medicine
    J P Vandenbroucke
    Department of Clinical Epidemiology, Leiden University Medical Center, Building 1, PO Box 9600, 2300 RC Leiden, The Netherlands
    Ann Intern Med 135:507-13. 2001
  3. ncbi In defense of case reports and case series
    J P Vandenbroucke
    Leiden University Hospital Medical Center, Leiden, The Netherlands
    Ann Intern Med 134:330-4. 2001
  4. ncbi Invited commentary: the testimony of Dr. Snow
    J P Vandenbroucke
    Department of Clinical Epidemiology, Leiden University Hospital Medical Centre, The Netherlands
    Am J Epidemiol 152:10-2. 2000
  5. pmc Experience with multiple control groups in a large population-based case-control study on genetic and environmental risk factors
    E R Pomp
    Department of Clinical Epidemiology, C7 P, Leiden University Medical Center, P O Box 9600, 2300 RC, Leiden, The Netherlands
    Eur J Epidemiol 25:459-66. 2010
  6. pmc The venous thrombotic risk of oral contraceptives, effects of oestrogen dose and progestogen type: results of the MEGA case-control study
    A Van Hylckama Vlieg
    Department of Clinical Epidemiology, Leiden University Medical Center, C7 P, PO Box 9600, NL 2300 RC Leiden, Netherlands
    BMJ 339:b2921. 2009
  7. pmc The risk for breast cancer is not evidently increased in women with hyperprolactinemia
    O M Dekkers
    Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, P O Box 9600, 2300 RC, Leiden, The Netherlands
    Pituitary 13:195-8. 2010
  8. ncbi Oral contraceptives and thrombotic disease: risk of venous thromboembolism
    F M Helmerhorst
    Department of Obstetrics, Gynecology and Reproductive Medicine, Leiden University, The Netherlands
    Thromb Haemost 78:327-33. 1997
  9. ncbi Assessment of a bleeding risk index in two cohorts of patients treated with oral anticoagulants
    F J van der Meer
    Department of Hematology, Academic Hospital Leiden, The Netherlands F J M
    Thromb Haemost 76:12-6. 1996
  10. ncbi Oral contraceptives, hormone replacement therapy and thrombosis
    F R Rosendaal
    Department of Hematology, Leiden University Medical Center, The Netherlands
    Thromb Haemost 86:112-23. 2001

Collaborators

Detail Information

Publications21

  1. ncbi Changing images of John Snow in the history of epidemiology
    J P Vandenbroucke
    Leiden University Medical Center
    Soz Praventivmed 46:288-93. 2001
    ..Several different lessons have been extracted from the interpretation and reinterpretation of Snow's work--according to prevailing insights. The story of John Snow continues to evolve, even into the 21st century...
  2. ncbi Alternative medicine: a "mirror image" for scientific reasoning in conventional medicine
    J P Vandenbroucke
    Department of Clinical Epidemiology, Leiden University Medical Center, Building 1, PO Box 9600, 2300 RC Leiden, The Netherlands
    Ann Intern Med 135:507-13. 2001
    ..It does not lead to complete and uncontrollable subjectivity because discernment between rivaling explanations is still possible through argument and counterargument...
  3. ncbi In defense of case reports and case series
    J P Vandenbroucke
    Leiden University Hospital Medical Center, Leiden, The Netherlands
    Ann Intern Med 134:330-4. 2001
    ..At the same time, good case reporting demands a clear focus to make explicit to the audience why a particular observation is important in the context of existing knowledge...
  4. ncbi Invited commentary: the testimony of Dr. Snow
    J P Vandenbroucke
    Department of Clinical Epidemiology, Leiden University Hospital Medical Centre, The Netherlands
    Am J Epidemiol 152:10-2. 2000
    ....
  5. pmc Experience with multiple control groups in a large population-based case-control study on genetic and environmental risk factors
    E R Pomp
    Department of Clinical Epidemiology, C7 P, Leiden University Medical Center, P O Box 9600, 2300 RC, Leiden, The Netherlands
    Eur J Epidemiol 25:459-66. 2010
    ..Our experience with the intricacies of dealing with two control groups may be useful to others when thinking about an optimal research design or the best statistical approach...
  6. pmc The venous thrombotic risk of oral contraceptives, effects of oestrogen dose and progestogen type: results of the MEGA case-control study
    A Van Hylckama Vlieg
    Department of Clinical Epidemiology, Leiden University Medical Center, C7 P, PO Box 9600, NL 2300 RC Leiden, Netherlands
    BMJ 339:b2921. 2009
    ..To assess the thrombotic risk associated with oral contraceptive use with a focus on dose of oestrogen and type of progestogen of oral contraceptives available in the Netherlands...
  7. pmc The risk for breast cancer is not evidently increased in women with hyperprolactinemia
    O M Dekkers
    Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, P O Box 9600, 2300 RC, Leiden, The Netherlands
    Pituitary 13:195-8. 2010
    ..The uncertainty about the exact risk that is due to the relatively low number of breast cancer cases, should be overcome by pooling results in a future meta-analysis...
  8. ncbi Oral contraceptives and thrombotic disease: risk of venous thromboembolism
    F M Helmerhorst
    Department of Obstetrics, Gynecology and Reproductive Medicine, Leiden University, The Netherlands
    Thromb Haemost 78:327-33. 1997
    ..The clinical consequence is therefore that second-generation OCs are the first choice in prescription to first-time users...
  9. ncbi Assessment of a bleeding risk index in two cohorts of patients treated with oral anticoagulants
    F J van der Meer
    Department of Hematology, Academic Hospital Leiden, The Netherlands F J M
    Thromb Haemost 76:12-6. 1996
    ..64 -0.42 * age +0.36 * achieved INR. These bleeding risk indexes can be used to assess the risk of major bleeding complications of individual patients and allow more individualized care by individual tailoring the desired anticoagulation...
  10. ncbi Oral contraceptives, hormone replacement therapy and thrombosis
    F R Rosendaal
    Department of Hematology, Leiden University Medical Center, The Netherlands
    Thromb Haemost 86:112-23. 2001
    ..First results are emerging that specific subgroups of women, with prothrombotic or other abnormalities, may be at risk, especially during the first years of use of hormone substitution...
  11. ncbi [From pill to pill: oral contraception, venous thrombosis and coagulation disorders]
    J P Vandenbroucke
    Departement Klinische Epidemiologie, Leids Universitair Medisch Centrum, PO Box 9600, 2300 RC Leiden, Nederland
    Verh K Acad Geneeskd Belg 63:243-52; discussion 252-5. 2001
    ..The developments were accelerated by the finding that "third generation oral contraceptives" are associated with a higher risk of venous thrombosis. The lecture describes these new scientific insights...
  12. ncbi Antipsychotic medication and venous thrombosis
    R Thomassen
    Department of Psychiatry, Leiden University Medical Center, The Netherlands
    Br J Psychiatry 179:63-6. 2001
    ..Recent epidemiological studies of good methodological quality have confirmed these findings. CONCLUSIONS: Venous thrombosis appears to be associated with the use of antipsychotic drugs in psychiatric patients...
  13. ncbi An association between cartilaginous tumours and breast cancer in the national pathology registration in The Netherlands points towards a possible genetic trait
    A E Odink
    Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands
    J Pathol 193:190-2. 2001
    ..e. 51 years versus 60.9 years. The association of breast cancer and cartilaginous tumours and the early age of onset of breast cancer in these patients may suggest a genetic trait...
  14. ncbi Increased end-stage diabetic nephropathy in Indo-Asian immigrants living in the Netherlands
    P K Chandie Shaw
    Department of Nephrology, C3 P, Leiden University Medical Center, Leiden, The Netherlands
    Diabetologia 45:337-41. 2002
    ..We aimed to investigate the risk of end-stage diabetic nephropathy due to Type II (non-insulin-dependent) diabetes mellitus in Indo-Asian immigrants from Surinam...
  15. doi How to assess the external validity of therapeutic trials: a conceptual approach
    O M Dekkers
    Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Epidemiol 39:89-94. 2010
    ..External validity of study results is an important issue from a clinical point of view. From a methodological point of view, however, the concept of external validity is more complex than it seems to be at first glance...
  16. pmc The tortuous history of the implementation of early ambulation after delivery
    K J van Stralen
    Department of Clinical Epidemiology, Division of Reproductive Medicine, Leiden University Medical Centre, The Netherlands
    J R Soc Med 100:90-6. 2007
  17. ncbi High factor VIII levels contribute to the thrombotic risk in families with factor V Leiden
    R Lensen
    Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands
    Br J Haematol 114:380-6. 2001
    ..These results and the higher thrombotic risks we found in the thrombophilic families favour the hypothesis that other unknown co-existing genetic defects contribute to thrombophilia...
  18. ncbi A comparative study of atypical and melanocytic naevi on the tropical island Curaçao and in The Netherlands
    M B Crijns
    Department of Dermatology, University Hospital, Leiden, The Netherlands
    Melanoma Res 5:161-7. 1995
    ..We found a generation-dependent difference in the expression of AN among White inhabitants of The Netherlands and on Curaçao, with a higher prevalence of AN in the younger generation...
  19. ncbi Female hormones and thrombosis
    F R Rosendaal
    Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    Arterioscler Thromb Vasc Biol 22:201-10. 2002
    ..The risk becomes very high in women with a previous venous thrombosis. Randomized trials have not confirmed a beneficial effect of postmenopausal hormones on the occurrence of myocardial infarction...
  20. doi Estimated age- and sex-specific incidence and prevalence of dopamine agonist-treated hyperprolactinemia
    M Kars
    Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
    J Clin Endocrinol Metab 94:2729-34. 2009
    ..Few data exist on sex- and age-specific incidence and prevalence of idiopathic hyperprolactinemia and prolactinomas...
  21. ncbi Hereditary antithrombin deficiency: heterogeneity of the molecular basis and mortality in Dutch families
    H H van Boven
    Department of Clinical Epidemiology, University Hospital, Leiden, The Netherlands
    Blood 84:4209-13. 1994
    ..We suggest that the longevity is not affected by molecular defects in the antithrombin gene and hypothesize that differences in mortality or natural history between families most likely result from other (genetic) risk factors...