Theo van Laar
Affiliation: Leiden University Medical Center
Country: The Netherlands
- A role for Rad23 proteins in 26S proteasome-dependent protein degradation?Theo van Laar
MGC Department of Radiation Genetics and Chemical Mutagenesis, Leiden University Medical Centre, P O Box 9503, 2300 RA Leiden, The Netherlands
Mutat Res 499:53-61. 2002..On the basis of its localization in the ER-membrane, it is hypothesized that Mif1 could play a role in the translocation of the 26S proteasome towards the ER-membrane, thereby enhancing ER-associated protein degradation...
- Mif1: a missing link between the unfolded protein response pathway and ER-associated protein degradation?T van Laar
MGC Department of Radiation Genetics and Chemical Mutagenesis, P O Box 9503, 2300 RA Leiden, The Netherlands
Curr Protein Pept Sci 2:169-90. 2001..It is anticipated that Mif1 may associate through its ubiquitin-like domain with the 26S proteasome, in this way connecting the protein degradation machinery to the ER membrane and resulting in an efficient ERAD...
- Expression of BNIP3 in invasive breast cancer: correlations with the hypoxic response and clinicopathological featuresEsther A Koop
Department of Pathology, University Medical Center, Utrecht, The Netherlands
BMC Cancer 9:175. 2009..The aim of the present study was to investigate the expression of BNIP3 in invasive breast cancer at the mRNA and protein level in correlation with the hypoxic response and clinicopathological features...