Jacobus J Van Hilten

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi Muscle weakness and lack of reflex gain adaptation predominate during post-stroke posture control of the wrist
    Carel G M Meskers
    Department of Rehabilitation Medicine, Leiden University Medical Center, Leiden, The Netherlands
    J Neuroeng Rehabil 6:29. 2009
  2. ncbi Movement disorders in complex regional pain syndrome
    Jacobus J Van Hilten
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Pain Med 11:1274-7. 2010
  3. ncbi Peripheral trauma and movement disorders
    Jacobus J Van Hilten
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Parkinsonism Relat Disord 13:S395-9. 2007
  4. ncbi Peripheral trauma and movement disorders: a systematic review of reported cases
    Diana E van Rooijen
    Department of Neurology, Leiden University Medical Centre, P O Box 9600, 2300 RC Leiden, The Netherlands
    J Neurol Neurosurg Psychiatry 82:892-8. 2011
  5. ncbi Genetic HLA associations in complex regional pain syndrome with and without dystonia
    Diana E van Rooijen
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    J Pain 13:784-9. 2012
  6. ncbi Efficacy of intrathecal baclofen on different pain qualities in complex regional pain syndrome
    Anton A van der Plas
    Department of Neurology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Anesth Analg 116:211-5. 2013
  7. ncbi Clinical subtypes of Parkinson's disease
    Stephanie M van Rooden
    Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands
    Mov Disord 26:51-8. 2011
  8. ncbi Efficacy and safety of a single intrathecal methylprednisolone bolus in chronic complex regional pain syndrome
    Alexander G Munts
    Department of Neurology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Eur J Pain 14:523-8. 2010
  9. ncbi Spontaneous onset of complex regional pain syndrome
    Annetje M de Rooij
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Eur J Pain 14:510-3. 2010
  10. ncbi Spreading of complex regional pain syndrome: not a random process
    Monique A van Rijn
    Department of Neurology K5Q, Leiden University Medical Center, P O Box 9600, 2300 RC, Leiden, The Netherlands
    J Neural Transm 118:1301-9. 2011

Detail Information

Publications48

  1. ncbi Muscle weakness and lack of reflex gain adaptation predominate during post-stroke posture control of the wrist
    Carel G M Meskers
    Department of Rehabilitation Medicine, Leiden University Medical Center, Leiden, The Netherlands
    J Neuroeng Rehabil 6:29. 2009
    ..We used a closed loop system identification technique to quantify individual contributors to wrist joint stiffness during an active posture task...
  2. ncbi Movement disorders in complex regional pain syndrome
    Jacobus J Van Hilten
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Pain Med 11:1274-7. 2010
    ..There are no randomized control studies on the treatment of movement disorders in CRPS but findings from fundamental and clinical research suggest that strategies that enhance the central inhibitory state may benefit these patients...
  3. ncbi Peripheral trauma and movement disorders
    Jacobus J Van Hilten
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Parkinsonism Relat Disord 13:S395-9. 2007
    ..Additionally, recent developments on the potential mechanisms that underlie dystonia in complex regional pain syndrome are used to illustrate how the relation between peripheral trauma and movement disorders may evolve...
  4. ncbi Peripheral trauma and movement disorders: a systematic review of reported cases
    Diana E van Rooijen
    Department of Neurology, Leiden University Medical Centre, P O Box 9600, 2300 RC Leiden, The Netherlands
    J Neurol Neurosurg Psychiatry 82:892-8. 2011
    ..To perform a systematic review of cases reported in the literature in which a peripheral trauma preceded the onset of a movement disorder (MD)...
  5. ncbi Genetic HLA associations in complex regional pain syndrome with and without dystonia
    Diana E van Rooijen
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    J Pain 13:784-9. 2012
    ..Moreover, associations of HLA-DQ8 with both CRPS with and CRPS without dystonia, and HLA-B62 only with CRPS with dystonia, suggest that these disease entities may be genetically different, but overlapping...
  6. ncbi Efficacy of intrathecal baclofen on different pain qualities in complex regional pain syndrome
    Anton A van der Plas
    Department of Neurology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Anesth Analg 116:211-5. 2013
    ..In this study, we evaluated the differential effects of central γ-aminobutyric acid (B) receptor stimulation on the different pain qualities in CRPS patients with dystonia...
  7. ncbi Clinical subtypes of Parkinson's disease
    Stephanie M van Rooden
    Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands
    Mov Disord 26:51-8. 2011
    ..In prevalent disease, PD subtypes are largely characterized by the severity of nondopaminergic features and motor complications and likely reflect complex interactions between disease mechanisms, treatment, aging, and gender...
  8. ncbi Efficacy and safety of a single intrathecal methylprednisolone bolus in chronic complex regional pain syndrome
    Alexander G Munts
    Department of Neurology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Eur J Pain 14:523-8. 2010
    ..We conclude that a single bolus administration of ITM is not efficacious in chronic CRPS patients, which may indicate that spinal immune activation does not play an important role in this phase of the syndrome...
  9. ncbi Spontaneous onset of complex regional pain syndrome
    Annetje M de Rooij
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Eur J Pain 14:510-3. 2010
    ....
  10. ncbi Spreading of complex regional pain syndrome: not a random process
    Monique A van Rijn
    Department of Neurology K5Q, Leiden University Medical Center, P O Box 9600, 2300 RC, Leiden, The Netherlands
    J Neural Transm 118:1301-9. 2011
    ..Spread is associated with a younger age at onset and a more severely affected phenotype. We argue that processes in the spinal cord as well as supraspinal changes are responsible for spontaneous spread in CRPS...
  11. ncbi Phenotypes and genetic architecture of focal primary torsion dystonia
    Justus L Groen
    Department of Neurology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 83:1006-11. 2012
    ..Thorough clinical description of FPTDs cohorts is sparse but essential for further progress in genetic research...
  12. ncbi Catechol-O-methyltransferase Val158Met and the risk of dyskinesias in Parkinson's disease
    Lonneke M L de Lau
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 27:132-5. 2012
    ..The A-allele of the catechol-O-methyltransferase (COMT) Val158Met polymorphism is associated with decreased enzymatic activity and higher dopamine availability...
  13. ncbi Intrathecal glycine for pain and dystonia in complex regional pain syndrome
    Alexander G Munts
    Department of Neurology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Pain 146:199-204. 2009
    ..ITG given over 4 weeks was ineffective for pain or dystonia in CRPS. Although no serious adverse events occurred, further studies are required to rule out potential neurotoxicity of ITG...
  14. ncbi Psychotic and compulsive symptoms in Parkinson's disease
    Dagmar Verbaan
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 24:738-44. 2009
    ..Our results confirm previous reports on the profile of patients developing CS, and mechanisms underlying motor fluctuations may also play a role in the development of CS in PD...
  15. ncbi Motor patterns in Parkinson's disease: a data-driven approach
    Stephanie M van Rooden
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 24:1042-7. 2009
    ..The identification of motor factors and their relation with other domains of the disease may help to elucidate the mechanisms responsible for these associations and provide an objective base for further research on subtypes in PD...
  16. ncbi Thermal hypesthesia in patients with complex regional pain syndrome related dystonia
    Alexander G Munts
    Department of Neurology, Leiden University Medical Center, P O Box 9600, 2300 RC, Leiden, The Netherlands
    J Neural Transm 118:599-603. 2011
    ..The degrees of cold and warmth hypesthesia were strongly correlated. We conclude that dysfunction in small nerve fiber (i.e., C and Aδ) processing is present in patients with CRPS-related dystonia...
  17. ncbi Systematic mutation analysis of seven dystonia genes in complex regional pain syndrome with fixed dystonia
    M Florencia Gosso
    Department of Human Genetics, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    J Neurol 257:820-4. 2010
    ..No such mutations were identified, indicating that these genes do not seem to play a major role in CRPS...
  18. ncbi Fixed dystonia in complex regional pain syndrome: a descriptive and computational modeling approach
    Alexander G Munts
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    BMC Neurol 11:53. 2011
    ..We hypothesized that dystonia could be the result of aberrant proprioceptive reflex strengths of position, velocity or force feedback...
  19. ncbi Psychological features of patients with complex regional pain syndrome type I related dystonia
    Wouter B Reedijk
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 23:1551-9. 2008
    ..Although the psychological profile of the patients with CRPS-I-related dystonia shows some elevations, there does not seem to be a unique disturbed psychological profile on a group level...
  20. ncbi Prevalence and clinical profile of restless legs syndrome in Parkinson's disease
    Dagmar Verbaan
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 25:2142-7. 2010
    ..It is hypothesized that, nondopaminergic systems, such as the noradrenergic system may play a role in the possible link between PD and RLS...
  21. ncbi Postdural puncture headache in complex regional pain syndrome: a retrospective observational study
    Alexander G Munts
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Pain Med 10:1469-75. 2009
    ..To describe the unusual course of postdural puncture headache (PDPH) after pump implantation for intrathecal baclofen (ITB) administration in patients with complex regional pain syndrome (CRPS)-related dystonia...
  22. ncbi Increased risk of complex regional pain syndrome in siblings of patients?
    Annetje M de Rooij
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    J Pain 10:1250-5. 2009
    ..To enhance chances of success, future genetic studies may consider restricting inclusion to younger-onset cases...
  23. ncbi SCOPA-cognition cutoff value for detection of Parkinson's disease dementia
    Dagmar Verbaan
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 26:1881-6. 2011
    ..The availability of SCOPA-Cognition cutoffs for Parkinson's disease dementia may contribute to the scale's usefulness and promote its further use in both clinical and research settings...
  24. ncbi DYT6 dystonia: mutation screening, phenotype, and response to deep brain stimulation
    Justus L Groen
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Mov Disord 25:2420-7. 2010
    ..Four DYT6 dystonia patients were treated with GPi DBS with moderate to good response on motor function but marginal benefit on speech...
  25. ncbi A comparative study of odor identification and odor discrimination deficits in Parkinson's disease
    Sanne Boesveldt
    Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
    Mov Disord 23:1984-90. 2008
    ..Although an odor identification deficit is generally believed to be independent of disease progression, the impairment in odor discrimination appears to increase with disease duration...
  26. ncbi Nighttime sleep problems and daytime sleepiness in Parkinson's disease
    Dagmar Verbaan
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 23:35-41. 2008
    ..No strong relations were found between DS and demographic or clinical variables. The strong relation between NSP and depressive symptoms in PD calls for future studies to explore the nature of this relation...
  27. ncbi Familial occurrence of complex regional pain syndrome
    Annetje M de Rooij
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Eur J Pain 13:171-7. 2009
    ..Patients with fCRPS develop the disease at a younger age and have a more severe phenotype than sporadic cases, suggesting a genetic predisposition to develop CRPS...
  28. ncbi Evaluation of the hospital anxiety and depression scale in patients with Parkinson's disease
    Johan Marinus
    Department of Neurology, Leiden University Medical Center, The Netherlands
    Clin Neuropharmacol 25:318-24. 2002
    ..5 and 16.9. The psychometric performance of the HADS in patients with PD is satisfactory. In addition, almost 50% of the patients displayed symptoms of anxiety, whereas nearly 40% showed signs of depression...
  29. ncbi Spatiotemporal integration of sensory stimuli in complex regional pain syndrome and dystonia
    Monique A van Rijn
    Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, The Netherlands
    J Neural Transm 116:559-65. 2009
    ..Central sensory integration of proprioceptive afferent input is normal in patients with CPRS-related dystonia. Other mechanisms may underlie the development of dystonia in this disorder...
  30. ncbi The identification of Parkinson's disease subtypes using cluster analysis: a systematic review
    Stephanie M van Rooden
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 25:969-78. 2010
    ..Future studies with a rigorous study design that is standardized with respect to the included variables, data processing, and CA technique may advance the knowledge on subtypes in PD...
  31. ncbi Analysis of cerebrospinal fluid inflammatory mediators in chronic complex regional pain syndrome related dystonia
    Alexander G Munts
    Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands
    Clin J Pain 24:30-4. 2008
    ..The aim of the present study was to replicate these findings and to search for additional CSF biomarkers in chronic CRPS patients with dystonia...
  32. ncbi Ketamine produces effective and long-term pain relief in patients with Complex Regional Pain Syndrome Type 1
    Marnix J Sigtermans
    Department of Anesthesiology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Pain 145:304-11. 2009
    ..Treatment with ketamine was safe with psychomimetic side effects that were acceptable to most patients...
  33. ncbi Reliability and validity of the Beck depression inventory in patients with Parkinson's disease
    Martine Visser
    Department of Neurology, Leiden University Medical Center, Leiden, and Deparment of Psychiatry, Maastricht University Hospital, The Netherlands
    Mov Disord 21:668-72. 2006
    ..The smallest real difference was 3.3 for the total BDI. The BDI is a valid, reliable, and potential responsive instrument to assess the severity of depression in PD. However, an adjusted cutoff is recommended...
  34. ncbi Clinical tests for the evaluation of postural instability in patients with parkinson's disease
    Martine Visser
    Departmentof Neurology, Leiden University Medical Center, The Netherlands
    Arch Phys Med Rehabil 84:1669-74. 2003
    ..To determine which test for postural instability in Parkinson's disease (PD) is reliable, valid, and easy to perform in a clinical setting...
  35. ncbi Assessment of autonomic dysfunction in Parkinson's disease: the SCOPA-AUT
    Martine Visser
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 19:1306-12. 2004
    ..We conclude that SCOPA-AUT is a reliable and valid questionnaire that evaluates autonomic dysfunction in PD...
  36. ncbi A short psychosocial questionnaire for patients with Parkinson's disease: the SCOPA-PS
    Johan Marinus
    Department of Neurology, Leiden University Medical Center K5 Q 92, P O Box 9600, NL 2300 RC Leiden, The Netherlands
    J Clin Epidemiol 56:61-7. 2003
    ..The summary index revealed a significant increase with increasing disease severity. The SCOPA-PS is a new, short psychosocial questionnaire for patients with PD with good clinimetric properties...
  37. ncbi Assessing comorbidity in patients with Parkinson's disease
    Martine Visser
    Department of Neurology of the Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 19:824-8. 2004
    ..40 (moderate agreement). The comorbidity summary scores had a moderate correlation with age and disability. The interview-based assessment of the CIRS-G is easy to apply and is an accurate method to assess comorbidity in patients with PD...
  38. ncbi Mutational analysis of TARDBP in Parkinson's disease
    Marka van Blitterswijk
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Neurobiol Aging 34:1517.e1-3. 2013
    ..S332S, no missense mutations were present in our cohort. Our findings, therefore, demonstrate that TARDBP mutations do not appear to contribute to the pathogenesis of Parkinson's disease in The Netherlands...
  39. ncbi Onset and progression of dystonia in complex regional pain syndrome
    Monique A van Rijn
    Department of Neurology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Pain 130:287-93. 2007
    ..The delayed onset and progression of dystonia in CRPS may indicate the involvement of a different underlying mechanism, possibly associated with maladaptive neuroplasticity...
  40. ncbi HLA-B62 and HLA-DQ8 are associated with Complex Regional Pain Syndrome with fixed dystonia
    Annetje M de Rooij
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Pain 145:82-5. 2009
    ..02 and HLA-DQ8 P(c)=0.04). The involvement of HLA-B62 and HLA-DQ8 in CRPS with dystonia may indicate that these HLA loci are implicated in the susceptibility or expression of the disease...
  41. ncbi Clinical features and pathophysiology of complex regional pain syndrome
    Johan Marinus
    Department of Neurology, Leiden University Medical Center, Leiden, Netherlands, TREND Knowledge Consortium, Leiden, Netherlands
    Lancet Neurol 10:637-48. 2011
    ..Variation in susceptibility to perturbed regulation of any of the underlying biological pathways probably accounts for the clinical heterogeneity of CRPS...
  42. ncbi Inflammation in complex regional pain syndrome: a systematic review and meta-analysis
    Luke Parkitny
    Neuroscience Research Australia, University of New South Wales, Sydney, Australia
    Neurology 80:106-17. 2013
    ....
  43. ncbi Clinical and neurophysiological characterization of myoclonus in complex regional pain syndrome
    Alexander G Munts
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 23:581-7. 2008
    ..Significant coherence entrainment was detected in 5 patients. We conclude that the characteristics of myoclonus in CRPS are different from other forms of myoclonus...
  44. ncbi Cerebral activation during motor imagery in complex regional pain syndrome type 1 with dystonia
    Esther W Gieteling
    Department of Neurology, University Medical Center Groningen, University of Groningen, P O Box 30 001, 9700 RB Groningen, The Netherlands
    Pain 134:302-9. 2008
    ....
  45. ncbi Explorative analysis of urine by capillary electrophoresis-mass spectrometry in chronic patients with complex regional pain syndrome
    Rawi Ramautar
    Biomolecular Mass Spectrometry Unit, Department of Parasitology, LUMC, Leiden, The Netherlands
    J Proteome Res 8:5559-67. 2009
    ....
  46. ncbi Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis
    Michael A van Es
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Ann Neurol 70:964-73. 2011
    ..We therefore investigated whether ANG variants could predispose to both ALS and PD...
  47. ncbi Clinical expression profiles of complex regional pain syndrome, fibromyalgia and a-specific repetitive strain injury: more common denominators than pain?
    Johan Marinus
    Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands
    Disabil Rehabil 28:351-62. 2006
    ....
  48. ncbi Assessment of psychiatric complications in Parkinson's disease: The SCOPA-PC
    Martine Visser
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 22:2221-8. 2007
    ..49. In conclusion, the SCOPA-PC is a reliable, valid, and easily-administered semistructured questionnaire for both psychotic and compulsive complications in PD...