Research Topics
| Desiree van der HeijdeSummaryAffiliation: Leiden University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Radiographic findings following two years of infliximab therapy in patients with ankylosing spondylitisDesiree van der Heijde
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Arthritis Rheum 58:3063-70. 2008..To evaluate the effect of infliximab on progression of structural damage over 2 years in patients with ankylosing spondylitis (AS)...
Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 yearsDesiree van der Heijde
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Arthritis Res Ther 11:R127. 2009..Our objective was to compare the progression of structural damage in the spine in patients with AS treated with adalimumab for up to 2 years versus patients who had not received TNF antagonist therapy...- Impact of ankylosing spondylitis on sick leave, presenteeism and unpaid productivity, and estimation of the societal costAnnelies Boonen
Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, P Debyelaan 25, Maastricht 6229HX, The Netherlands
Ann Rheum Dis 69:1123-8. 2010..To describe the influence of ankylosing apondylitis (AS) on sick leave, presenteeism and unpaid work restrictions and to estimate related productivity costs... - Justification for including MRI as a tool in the diagnosis of axial SpADesiree van der Heijde
Department of Rheumatology C1 R46, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Nat Rev Rheumatol 6:670-2. 2010..Even longer-term follow-up (>10 years) is necessary to provide reliable data; however, the validity of MRI in the diagnostic process can only be approximated, as it will never cover the entire gestalt of SpA... - 2010 Update of the international ASAS recommendations for the use of anti-TNF agents in patients with axial spondyloarthritisDesiree van der Heijde
Department of Rheumatology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Ann Rheum Dis 70:905-8. 2011..Sulfasalazine is no longer mandatory in this group of patients. Finally, efficacy should be evaluated after at least 12 weeks. The remaining recommendations stayed largely unchanged... - Comparison of three enthesitis indices in a multicentre, randomized, placebo-controlled trial of golimumab in ankylosing spondylitis (GO-RAISE)Desiree van der Heijde
Rheumatology, Leiden University Medical Center, Leiden, PO Box 9600, 2300 RC Leiden, The Netherlands
Rheumatology (Oxford) 52:321-5. 2013..To compare the abilities of three enthesitis indices to detect improvement in entheseal tenderness with the TNF antagonist golimumab in AS... - Timing and magnitude of initial change in disease activity score 28 predicts the likelihood of achieving low disease activity at 1 year in rheumatoid arthritis patients treated with certolizumab pegol: a post-hoc analysis of the RAPID 1 trialDesiree van der Heijde
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
J Rheumatol 39:1326-33. 2012.... - Remission by imaging in rheumatoid arthritis: should this be the ultimate goal?Desiree van der Heijde
Department of Rheumatology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Ann Rheum Dis 71:i89-92. 2012..This proof is not yet available, and too many unanswered questions remain to recommend including imaging remission of inflammation in a definition of remission... - MRI inflammation at the vertebral unit only marginally predicts new syndesmophyte formation: a multilevel analysis in patients with ankylosing spondylitisDesiree van der Heijde
Rheumatology Department, Leiden University Medical Center, Leiden, The Netherlands
Ann Rheum Dis 71:369-73. 2012..To investigate the relationship between MRI inflammation at the vertebral unit and the formation and growth of syndesmophytes at the same vertebral unit... - The impact of infliximab treatment on quality of life in patients with inflammatory rheumatic diseasesChenglong Han
Centocor Research and Development, Inc, 200 Great Valley Parkway, Malvern, Pennsylvania 19355, USA
Arthritis Res Ther 9:R103. 2007..Patients in large randomized controlled studies of infliximab in RA, PsA, and AS had similar impairment in physical aspects of HRQoL at baseline and showed significantly greater improvement in HRQoL after treatment with infliximab... - The prognostic value of baseline erosions in undifferentiated arthritisMohamed M Thabet
Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, Leiden, PO Box 9600, 2300RC, The Netherlands
Arthritis Res Ther 11:R155. 2009..This study evaluates the predictive value of erosive joints for the disease outcome in UA as measured by RA development and disease persistency... - The likelihood of persistent arthritis increases with the level of anti-citrullinated peptide antibody and immunoglobulin M rheumatoid factor: a longitudinal study of 376 patients with very early undifferentiated arthritisMaria D Mjaavatten
Department of Rheumatology, Diakonhjemmet Hospital, P, O, Box 23 Vinderen, 0319 Oslo, Norway
Arthritis Res Ther 12:R76. 2010.... 
Disease remission and sustained halting of radiographic progression with combination etanercept and methotrexate in patients with rheumatoid arthritisD van der Heijde
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Arthritis Rheum 56:3928-39. 2007..The results after 1 and 2 years of the study have been previously reported. Here we provide the 3-year clinical and radiographic outcomes and safety of etanercept, methotrexate, and the combination in patients with RA...- Repair in rheumatoid arthritis, current status. Report of a workshop at OMERACT 8Desiree van der Heijde
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, and CAPHRI Research Institute, University Maastricht, The Netherlands
J Rheumatol 34:884-8. 2007..e., not limited to sum scores of all joints together. The conclusions of the workshop mean a big step forward in the acceptance and assessment of repair... - Spondyloarthritis: state of the art and future perspectivesDesiree van der Heijde
Department of Rheumatology, C1R, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Ann Rheum Dis 69:949-54. 2010.... - ASDAS, a highly discriminatory ASAS-endorsed disease activity score in patients with ankylosing spondylitisD van der Heijde
Department of Rheumatology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
Ann Rheum Dis 68:1811-8. 2009.... - Proposal of a linear definition of the Bath Ankylosing Spondylitis Metrology Index (BASMI) and comparison with the 2-step and 10-step definitionsD van der Heijde
Department of Rheumatology, Leiden University Medical Center, Leiden, PO Box 9600, 2300 RC Leiden, The Netherlands
Ann Rheum Dis 67:489-93. 2008..For metric purposes, we recently defined a BASMI version with linear score definitions. Aim: to evaluate agreement between three BASMI definitions and to test sensitivity to change... - The safety and efficacy of adding etanercept to methotrexate or methotrexate to etanercept in moderately active rheumatoid arthritis patients previously treated with monotherapyD van der Heijde
Leiden University Medical Center, PO Box 9600, 2300RC Leiden, The Netherlands
Ann Rheum Dis 67:182-8. 2008..To determine if adding etanercept (ETN) to methotrexate (MTX) or MTX to ETN for 52 weeks in rheumatoid arthritis (RA) patients with moderate disease activity provides higher efficacy... - Physical function, disease activity, and health-related quality-of-life outcomes after 3 years of adalimumab treatment in patients with ankylosing spondylitisDésirée M van der Heijde
Department of Rheumatology, Leiden University Medical Center, Leiden, Leiden, The Netherlands
Arthritis Res Ther 11:R124. 2009..We evaluated the three-year impact of adalimumab on patient-reported physical function and health-related quality-of-life (HRQOL) outcomes in patients with active ankylosing spondylitis (AS)... - Infliximab inhibits progression of radiographic damage in patients with active psoriatic arthritis through one year of treatment: Results from the induction and maintenance psoriatic arthritis clinical trial 2D van der Heijde
Leiden University Medical Center, Leiden, The Netherlands
Arthritis Rheum 56:2698-707. 2007..To evaluate the effect of infliximab on progression of structural damage over 1 year in patients with active psoriatic arthritis (PsA) enrolled in the Induction and Maintenance Psoriatic Arthritis Clinical Trial 2... - Expert agreement confirms that negative changes in hand and foot radiographs are a surrogate for repair in patients with rheumatoid arthritisDesiree van der Heijde
Department of Rheumatology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands
Arthritis Res Ther 9:R62. 2007..The change in size of erosion was also picked up by independent readers applying the van der Heijde-modified Sharp scoring method and was reflected in their scores... - Adalimumab effectively reduces the signs and symptoms of active ankylosing spondylitis in patients with total spinal ankylosisD van der Heijde
Leiden University Medical Center, Leiden, The Netherlands
Ann Rheum Dis 67:1218-21. 2008..To evaluate the long-term safety and efficacy of adalimumab in patients with ankylosing spondylitis (AS) and total spinal ankylosis (TSA)... - Adalimumab effectiveness for the treatment of ankylosing spondylitis is maintained for up to 2 years: long-term results from the ATLAS trialD van der Heijde
Department of Rheumatology, Leiden University Medical Center, The Netherlands
Ann Rheum Dis 68:922-9. 2009.... - Inhibition of radiographic progression with combination etanercept and methotrexate in patients with moderately active rheumatoid arthritis previously treated with monotherapyD van der Heijde
Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Ann Rheum Dis 68:1113-8. 2009..To determine the effect of changing from etanercept or methotrexate monotherapy to etanercept plus methotrexate combination therapy on radiographic progression in rheumatoid arthritis (RA) patients... - Comparison of recommendations for the use of anti-tumour necrosis factor therapy in ankylosing spondylitis in 23 countries worldwideRosaline van den Berg
Department of Rheumatology, Leiden University Medical Centre, RC Leiden, The Netherlands
Rheumatology (Oxford) 50:2270-7. 2011..To give an overview of the recommendations for the use of anti-TNF-α therapy in AS in 23 countries worldwide... - Radiographic progression of ankylosing spondylitis after up to two years of treatment with etanerceptD van der Heijde
Leiden University Medical Center, Leiden, The Netherlands
Arthritis Rheum 58:1324-31. 2008..To investigate the effect of etanercept therapy on radiographic progression in patients with ankylosing spondylitis (AS)... - Erosions versus joint space narrowing in rheumatoid arthritis: what do we know?Desiree van der Heijde
Department of Rheumatology, C1 43, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Ann Rheum Dis 70:i116-8. 2011..Repair is possible for erosions as well as JSN and this is related to the absence of inflammation and effective treatment (especially methotrexate in combination with a tumour necrosis factor blocker)... - Level of radiographic damage and radiographic progression are determinants of physical function: a longitudinal analysis of the TEMPO trialD van der Heijde
Department of Rheumatology, Leiden University Medical Centre, PO Box 9600, 2300 CC Leiden, The Netherlands
Ann Rheum Dis 67:1267-70. 2008..Aim: To investigate the longitudinal relationship between physical function and both the level of radiographic damage and the radiographic progression rate in patients with early or advanced active rheumatoid arthritis... - Disconnect between inflammation and joint destruction after treatment with etanercept plus methotrexate: results from the trial of etanercept and methotrexate with radiographic and patient outcomesRobert Landewe
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 54:3119-25. 2006.... - MRI inflammation and its relation with measures of clinical disease activity and different treatment responses in patients with ankylosing spondylitis treated with a tumour necrosis factor inhibitorPedro Machado
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Ann Rheum Dis 71:2002-5. 2012..To investigate the relationship between MRI inflammation and measures of clinical disease activity as well as treatment responses in patients with ankylosing spondylitis (AS) treated with a tumour necrosis factor inhibitor... - Smokers in early axial spondyloarthritis have earlier disease onset, more disease activity, inflammation and damage, and poorer function and health-related quality of life: results from the DESIR cohortHo Yin Chung
Department of Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands
Ann Rheum Dis 71:809-16. 2012..To investigate the association of smoking with various clinical, functional and imaging outcomes in patients with early axial spondyloarthritis (SpA)... - Is there a preferred method for scoring activity of the spine by magnetic resonance imaging in ankylosing spondylitis?Desiree van der Heijde
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht and CAPHRI Research Institute, University Maastricht, The Netherlands d vanderheijde kpnplanet nl
J Rheumatol 34:871-3. 2007..The Berlin and SPARCC methods were preferred most frequently. The development of a new method combining the best elements of all methods is an additional possibility... - Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis: two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trialDesiree van der Heijde
Department of Rheumatology, University Hospital, Maastricht, The Netherlands
Arthritis Rheum 54:1063-74. 2006.... - How do the EQ-5D, SF-6D and the well-being rating scale compare in patients with ankylosing spondylitis?Annelies Boonen
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Ann Rheum Dis 66:771-7. 2007..Purpose: To compare aspects of validity of EuroQol-5 Dimensions (EQ-5D) and Short-Form-6 Dimensions (SF-6D), two indirect utility instruments, and the well-being rating scale (RS) in ankylosing spondylitis (AS)... - Efficacy and safety of adalimumab in patients with ankylosing spondylitis: results of a multicenter, randomized, double-blind, placebo-controlled trialDesiree van der Heijde
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 54:2136-46. 2006..To evaluate the safety and efficacy of adalimumab, a fully human recombinant IgG1 monoclonal antibody that specifically targets human tumor necrosis factor, in patients with active ankylosing spondylitis (AS)... - Presentation and analysis of data on radiographic outcome in clinical trials: experience from the TEMPO studyDesiree van der Heijde
Rheumatology Department, University Hospital, Maastricht, The Netherlands
Arthritis Rheum 52:49-60. 2005..To evaluate different methods of presentation and analysis of radiographic data in a rheumatoid arthritis (RA) randomized controlled trial... - Scoring inflammatory activity of the spine by magnetic resonance imaging in ankylosing spondylitis: a multireader experimentCédric Lukas
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, The Netherlands
J Rheumatol 34:862-70. 2007..We investigated feasibility, inter-reader reliability, sensitivity to change, and discriminatory ability of 3 different scoring methods for MRI activity and change in activity of the spine in patients with AS... - Comparison of three methods for calculating the Bath Ankylosing Spondylitis Metrology Index in a randomized placebo-controlled studyDesiree van der Heijde
Leiden University Medical Center, Leiden, The Netherlands
Arthritis Care Res (Hoboken) 64:1919-22. 2012..To compare 3 methods for calculating the Bath Ankylosing Spondylitis Metrology Index (BASMI) score using patients who participated in the GO-RAISE study... - Sensitivity and discriminatory ability of the Ankylosing Spondylitis Disease Activity Score in patients treated with etanercept or sulphasalazine in the ASCEND trialDesiree van der Heijde
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Rheumatology (Oxford) 51:1894-905. 2012.... - Are syndesmophytes most prevalent in the lumbar or in the cervical spine in patients with ankylosing spondylitis and do they develop in a specific direction?Astrid van Tubergen
Department of Medicine, Division of Rheumatology, Maastricht University Medical Center, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Rheumatology (Oxford) 51:1432-9. 2012..To describe the distribution of prevalent syndesmophytes and bridges, and the occurrence of new ones in a prevalence cohort of patients with AS... - HLA-B27 positive patients differ from HLA-B27 negative patients in clinical presentation and imaging: results from the DESIR cohort of patients with recent onset axial spondyloarthritisHo Yin Chung
Rheumatology, Leiden University Medical Centre, Leiden, The Netherlands
Ann Rheum Dis 70:1930-6. 2011..To clarify the influence of human leucocyte antigen B27 (HLA-B27) status on the phenotype of early axial spondyloarthritis (SpA)... - Assessment of fatigue in patients with ankylosing spondylitis: a psychometric analysisAstrid van Tubergen
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 47:8-16. 2002.... - Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: results from two large early arthritis cohortsDiane Van der Woude
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Arthritis Rheum 60:2262-71. 2009.... - The influence of peripheral arthritis on disease activity in ankylosing spondylitis patients as measured with the Bath Ankylosing Spondylitis Disease Activity IndexLiesbeth Heuft-Dorenbosch
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 51:154-9. 2004..To investigate whether scores on the BASDAI change by omitting the 2 questions on peripheral disease... - Markers for type II collagen breakdown predict the effect of disease-modifying treatment on long-term radiographic progression in patients with rheumatoid arthritisRobert Landewe
Department of Internal Medicine Rheumatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Arthritis Rheum 50:1390-9. 2004.... - Development of new syndesmophytes and bridges in ankylosing spondylitis and their predictors: a longitudinal studyAstrid van Tubergen
Department of Medicine, Division of Rheumatology, Maastricht University Medical Center, The Netherlands
Ann Rheum Dis 71:518-23. 2012..Structural damage of the spine in ankylosing spondylitis (AS) is associated with worse physical function and impaired spinal mobility. Knowledge about predictors of new syndesmophyte formation is limited... - Measurement of spinal mobility in ankylosing spondylitis: comparison of occiput-to-wall and tragus-to-wall distanceLiesbeth Heuft-Dorenbosch
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, Maastricht, The Netherlands
J Rheumatol 31:1779-84. 2004..To investigate if the tragus-to-wall distance (TWD) is more reliable compared to the occiput-to-wall distance (OWD) as a measurement for thoracic spine extension in patients with ankylosing spondylitis (AS)... - Which aspects of functioning are relevant for patients with ankylosing spondylitis: results of focus group interviewsAnnelies Boonen
Department of Internal Medicine, Division of Rheumatology and Caphri Research Institute, Maastricht University Medical Center, Maastricht, The Netherlands
J Rheumatol 36:2501-11. 2009..To investigate whether concepts important to patients with ankylosing spondylitis (AS) are covered by disease-specific self-report health status instruments... - Efficacy and safety of infliximab in patients with ankylosing spondylitis: results of a randomized, placebo-controlled trial (ASSERT)Desiree van der Heijde
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 52:582-91. 2005..The objective of this multicenter, randomized, placebo-controlled study was to evaluate the efficacy and safety of infliximab in patients with AS... - How to avoid phenotypic misclassification in using joint destruction as an outcome measure for rheumatoid arthritis?Annette H M van der Helm-van Mil
Department of Rheumatology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Rheumatology (Oxford) 49:1429-35. 2010.... - Disease activity, physical function, and radiographic progression after longterm therapy with adalimumab plus methotrexate: 5-year results of PREMIERDesiree van der Heijde
Leiden University Medical Center, Leiden, The Netherlands
J Rheumatol 37:2237-46. 2010..To evaluate the efficacy and safety of initial combination treatment with adalimumab (ADA) and methotrexate (MTX) versus monotherapy with ADA or MTX during an open-label extension of PREMIER... - Infliximab improves productivity and reduces workday loss in patients with ankylosing spondylitis: results from a randomized, placebo-controlled trialDesiree van der Heijde
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 55:569-74. 2006.... - Cost effectiveness of combined spa-exercise therapy in ankylosing spondylitis: a randomized controlled trialAstrid van Tubergen
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 47:459-67. 2002.... - Radiographic progression in rheumatoid arthritisRobert Landewe
University Hospital Maastricht, Department Internal Medicine Rheumatology, P O Box 5800, 6202AZ Maastricht, The Netherlands
Clin Exp Rheumatol 23:S63-8. 2005.... - Quantification of radiological damage in inflammatory arthritis: rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitisDesiree van der Heijde
Division of Rheumatology, Department of Internal Medicine, University Hospital Maastricht, P Debyelaan 25, PO Box 5800, Maastricht 6202 AZ, The Netherlands
Best Pract Res Clin Rheumatol 18:847-60. 2004..The various methods for the three diseases are detailed in this chapter. Most information is available for rheumatoid and for this disease the relationship between radiological damage and long-term outcome is summarised... - ASsessment in Ankylosing Spondylitis International Working Group/Spondylitis Association of America recommendations for conducting clinical trials in ankylosing spondylitisDesiree van der Heijde
University Hospital Maastricht, and the Care and Public Health Research Institute of the University Maastricht, Maastricht, The Netherlands
Arthritis Rheum 52:386-94. 2005 - First update of the current evidence for the management of ankylosing spondylitis with non-pharmacological treatment and non-biologic drugs: a systematic literature review for the ASAS/EULAR management recommendations in ankylosing spondylitisRosaline van den Berg
Department of Rheumatology, Leiden University Medical Centre, PO Box 9600, 2300 RC Leiden, The Netherlands
Rheumatology (Oxford) 51:1388-96. 2012.... - Selection of a method for scoring radiographs for ankylosing spondylitis clinical trials, by the Assessment in Ankylosing Spondylitis Working Group and OMERACTDesiree van der Heijde
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, University Maastricht, 6202 AZ Maastricht, The Netherlands
J Rheumatol 32:2048-9. 2005..Finally, both the ASAS Working Group and OMERACT participants voted for the modified Stoke AS Spinal Score (mSASSS) as the preferred scoring method for use in clinical trials in AS... - Detecting radiological changes in rheumatoid arthritis that are considered important by clinical experts: influence of reading with or without known sequenceKarin Bruynesteyn
Division of Rheumatology, Maastricht University, Maastricht, The Netherlands
J Rheumatol 29:2306-12. 2002.... - Magnetic resonance imaging changes of sacroiliac joints in patients with recent-onset inflammatory back pain: inter-reader reliability and prevalence of abnormalitiesLiesbeth Heuft-Dorenbosch
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, The Netherlands
Arthritis Res Ther 8:R11. 2006..About one-third of patients with recent-onset inflammatory back pain show inflammation, and about one-sixth show structural changes in at least one SI joint... - Multiple computer-based methods of measuring joint space width can discriminate between treatment arms in the COBRA trial -- Update of an ongoing OMERACT projectJohn T Sharp
Maastricht University Medical Center, Department of Internal Medicine, Subdivision of Rheumatology, Maastricht, The Netherlands
J Rheumatol 36:1825-8. 2009..98 or 0.99 for 4 programs. The smallest detectable change was < 0.2 mm for 4 of the 5 programs, representing 29%-36% of the change within the 99th percentile of measurements... - OMERACT workshop: repair of structural damage in rheumatoid arthritisDesiree van der Heijde
University Hospital Maastricht, Maastricht, The Netherlands
J Rheumatol 30:1108-9. 2003.... - Use of a numerical rating scale as an answer modality in ankylosing spondylitis-specific questionnairesAstrid van Tubergen
Department of Internal Medicine, University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 47:242-8. 2002..To assess the reproducibility and responsiveness of the instruments with the original scale and NRS... - Aspects relevant for functioning in patients with ankylosing spondylitis according to the health professionals: a Delphi study with the ICF as referenceAnnelies Boonen
Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands
Rheumatology (Oxford) 48:997-1002. 2009..This study aimed to achieve consensus among health professionals on which aspects of functioning are typical and relevant for AS patients using the International Classification of Functioning, Disability and Health (ICF) as reference... - A stratified model for health outcomes in ankylosing spondylitisPedro Machado
Department of Rheumatology, Coimbra University Hospital, Coimbra, Portugal
Ann Rheum Dis 70:1758-64. 2011..To investigate the relationships between several health outcomes in ankylosing spondylitis (AS)... - Continuous NSAID use reverts the effects of inflammation on radiographic progression in patients with ankylosing spondylitisFéline Kroon
Leiden University Medical Center, Rheumatology, PO Box 9600, 2300 RC Leiden, The Netherlands
Ann Rheum Dis 71:1623-9. 2012.... - How to report radiographic data in randomized clinical trials in rheumatoid arthritis: guidelines from a roundtable discussionDesiree van der Heijde
Department of Internal Medicine, University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Rheum 47:215-8. 2002 - The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28Robert Landewe
University Hospital Maastricht, Department of Internal Medicine Rheumatology, Maastricht, The Netherlands
Arthritis Res Ther 8:107. 2006..This commentary elaborates on how such a measure of severity should be validated to determine whether it is appropriate for practical use... - Evaluation of the efficacy of etoricoxib in ankylosing spondylitis: results of a fifty-two-week, randomized, controlled studyDesiree van der Heijde
Department of Internal Medicine, Division of Rheumatology, University Hospital, Maastricht, The Netherlands
Arthritis Rheum 52:1205-15. 2005..To assess the efficacy, safety, and tolerability of etoricoxib, a cyclooxygenase 2 (COX-2) selective inhibitor, administered continuously over 52 weeks for the treatment of ankylosing spondylitis (AS)... - Performance of classification criteria for peripheral spondyloarthritis and psoriatic arthritis in the Leiden Early Arthritis cohortRosaline van den Berg
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Ann Rheum Dis 71:1366-9. 2012..Therefore, the authors tested their performance in the Leiden Early Arthritis Clinic (EAC) cohort and assessed whether these criteria can assist rheumatologists in diagnosing patients... - Structural damage in rheumatoid arthritis as visualized through radiographsDesiree van der Heijde
University Hospital Maastricht, Maastricht, The Netherlands
Arthritis Res 4:S29-33. 2002..A guide in the interpretation and clinical relevance of radiographic results is presented, with the Anti-TNF Trial in Rheumatoid Arthritis with Concomitant Therapy used as an example... - The compliance-questionnaire-rheumatology compared with electronic medication event monitoring: a validation studyErik de Klerk
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, 6202 AZ Maastricht, The Netherlands
J Rheumatol 30:2469-75. 2003..35). CONCLUSION: These results support the validity of the Compliance Questionnaire Rheumatology... - Radiological scoring methods in ankylosing spondylitis. Reliability and change over 1 and 2 yearsAnneke Spoorenberg
University Hospital Maastricht, Maastricht, The Netherlands
J Rheumatol 31:125-32. 2004..Under the selected scoring conditions (concealed time order, average of 2 observers, SDD based on interobserver data, unselected patient population) there was too little change over 2 years to be detected reliably by the scoring methods... - The Sharp/van der Heijde method out-performed the Larsen/Scott method on the individual patient level in assessing radiographs in early rheumatoid arthritisKarin Bruynesteyn
Department of Internal Medicine, Division of Rheumatology, University of Maastricht, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands
J Clin Epidemiol 57:502-12. 2004..2%). The SvH also assessed changes in scores in individuals with less measurement error (SDCs 1.3-2.2%) than the LS (SDCs 2.3-3.9%). CONCLUSION: For early RA patients, the SvH seems preferable if analyses on individual level are included... - How to measure disease activity in axial spondyloarthritis?Pedro Machado
Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
Curr Opin Rheumatol 23:339-45. 2011..Recent efforts have been made to improve disease activity measurement in axial SpA... - Primer: challenges in randomized and observational studiesRobert Landewe
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Nat Clin Pract Rheumatol 3:661-6. 2007..This Review compares RCTs and observational studies with regard to particular limitations, and explains how the credibility of results from observational studies can be improved by making use of advanced analytical techniques... - Conventional x-ray in early arthritisAnnelies Boonen
Division of Rheumatology, Department of Internal Medicine, University Hospital Maastricht Care and Public Health Research Institute, University Maastricht, P Debyelaan 25, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Rheum Dis Clin North Am 31:681-98. 2005..The large number of patients with zero values for erosions and lower progression rates will influence sample sizes in clinical trials in early inflammatory arthritis when including radiographic change as an outcome... - A randomized clinical trial comparing fitness and biofeedback training versus basic treatment in patients with fibromyalgiaMarijke van Santen
Department of Internal Medicine, University Hospital Maastricht, The Netherlands
J Rheumatol 29:575-81. 2002..To compare the therapeutic effects of physical fitness training or biofeedback training with the results of usual care in patients with fibromyalgia (FM)... - Patient compliance in rheumatoid arthritis, polymyalgia rheumatica, and goutErik de Klerk
Division of Rheumatology, University Hospital Maastricht, The Netherlands
J Rheumatol 30:44-54. 2003..Compliance declines over time. A regression model shows that it is possible to relate differences in patient compliance to a number of medication and patient related factors... - Progression of rheumatoid arthritis on plain radiographs judged differently by expert radiologists and rheumatologistsKarin Bruynesteyn
Department of Internal Medicine, Division of Rheumatology and the Department of Radiology, University Hospital Maastricht, Maastricht, The Netherlands
J Rheumatol 31:1088-94. 2004..Thus, the radiologists appeared to be reserved in judging changes as important... - New directions in classification and outcome assessment in ankylosing spondylitisDesiree van der Heijde
Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, Caphri Research Institute, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Curr Rheumatol Rep 6:98-101. 2004..Responders as defined by the Assessment in Ankylosing Spondylitis response criteria also are considered by the experts as responders... - Impact of imaging in established rheumatoid arthritisDesiree van der Heijde
University Hospital Maastricht, P O Box 5800, 6202 AZ, Maastricht, The Netherlands
Best Pract Res Clin Rheumatol 17:783-90. 2003..The significance and clinical implication of a certain magnitude of change in the modified Sharp score is discussed... - Endorsement of definitions of disease activity states and improvement scores for the Ankylosing Spondylitis Disease Activity Score: results from OMERACT 10Pedro M M C Machado
Department of Rheumatology, Coimbra University Hospital, Coimbra, Portugal
J Rheumatol 38:1502-6. 2011..OMERACT participants agreed with the selection of cutoff values, which now have the combined endorsement of ASAS and OMERACT and are ready to be used in clinical practice and in research settings... - Doctor-patient interaction: standardized patients' reflections from inside the rheumatological officeSimone Gorter
Department of Internal Medicine, University Hospital Maastricht, The Netherlands
J Rheumatol 29:1496-500. 2002..Most critical comments from patients regarding communication and behavior were on small things, which should not be too difficult to change in daily practice... - Reproducibility of clinical performance assessment in practice using incognito standardized patientsSimone Gorter
Division of Rheumatology, Department of Internal Medicine, University Hospital Maastricht, 6200 MD Maastricht, The Netherlands
Med Educ 36:827-32. 2002..CONCLUSION: The reproducibility of performance assessment in clinical practice by incognito standardized patients is similar to that of other authentic measurements for the assessment of clinical competence and performance...