Research Topics
| Cornelis Jh van de VeldeSummaryAffiliation: Leiden University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Local and distant recurrences in rectal cancer patients are predicted by the nonspecific immune response; specific immune response has only a systemic effect--a histopathological and immunohistochemical studyI D Nagtegaal
Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
BMC Cancer 1:7. 2001..Data concerning involvement of individual cell types are readily available but little is known about the coordinate interactions between both forms of immune response...
Preoperative chemotherapy in primary operable breast cancer: results from the European Organization for Research and Treatment of Cancer trial 10902J A van der Hage
European Organization for Research and Treatment of Cancer Data Center, Brussels, Belgium
J Clin Oncol 19:4224-37. 2001....
Improved survival after one course of perioperative chemotherapy in early breast cancer patients. long-term results from the European Organization for Research and Treatment of Cancer (EORTC) Trial 10854J A van der Hage
European Organization for Research and Treatment of Cancer Data Center, Brussels, Belgium
Eur J Cancer 37:2184-93. 2001..65). One course of perioperative polychemotherapy does improve PFS and locoregional control in early stage breast cancers. This effect is still present after 11 years of follow-up...
Estimating number of events from the Kaplan-Meier curve for incorporation in a literature-based meta-analysis: what you don't see you can't get!L Duchateau
EORTC, Brussels, Belgium
Biometrics 56:886-92. 2000....
The role of meta-analyses in assessing cancer treatmentsR Sylvester
European Organization for Research and Treatment of Cancer EORTC Data Center, Avenue E Mounier 83, Bte 11, 1200, Brussels, Belgium
Eur J Cancer 36:1351-8. 2000....
Doxorubicin and paclitaxel versus doxorubicin and cyclophosphamide as first-line chemotherapy in metastatic breast cancer: The European Organization for Research and Treatment of Cancer 10961 Multicenter Phase III TrialL Biganzoli
Investigational Drug Branch for Breast Cancer, European Organization for the Research and Treatment of Cancer Data Center, and Jules Bordet Institute, Brussels, Belgium
J Clin Oncol 20:3114-21. 2002..CONCLUSION: No differences in the efficacy study end points were observed between the two treatment arms. Treatment-related toxicity compromised doxorubicin-delivered dose-intensity in the paclitaxel-based regimen..
Validation of prognostic indices using the frailty modelC Legrand
European Organisation for Research and Treatment of Cancer, 1200, Brussels, Belgium
Lifetime Data Anal 15:59-78. 2009..Our approach is applied to a real bladder cancer database for which we demonstrate how to investigate and interpret heterogeneity in prognostic index effect over centers...
Individual patient-versus literature-based meta-analysis of survival data: time to event and event rate at a particular time can make a difference, an example based on head and neck cancerL Duchateau
European Organization for Research and Treatment of Cancer EORTC, Brussels, Belgium
Control Clin Trials 22:538-47. 2001..Mortality can change substantially with follow-up time. The absolute survival differences in the case study, for instance, increase from 2.6% at 2 years to 5.6% at 5 years...
Continuing chemotherapy or not after the induction treatment in advanced breast cancer patients. clinical outcomes and oncologists' preferencesM A Nooij
Department of Clinical Oncology, Leiden University Medical Centre, Albinusdreef 2, The Netherlands
Eur J Cancer 39:614-21. 2003..Based on these data, an interruption of chemotherapy (CMF), if this is the wish of the patient, is justified...
Risk factors for recurrence and metastasis after breast-conserving therapy for ductal carcinoma-in-situ: analysis of European Organization for Research and Treatment of Cancer Trial 10853N Bijker
Departments of Radiation Oncology and Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
J Clin Oncol 19:2263-71. 2001..Margin status is the most important factor in the success of BCT for DCIS; additionally, young age and symptomatic detection of DCIS have negative prognostic value...
Variations in diagnostic and therapeutic procedures in a multicentre, randomized clinical trial (EORTC 10853) investigating breast-conserving treatment for DCISN Bijker
Department of Pathology, The Netherlands Cancer Institute Antoni van Leeuwenhoek ziekenhuis, Amsterdam, The Netherlands
Eur J Surg Oncol 27:135-40. 2001..The risk of local recurrence in itself, and hence the success of BCT for DCIS, may however be influenced by the quality of the initial procedures that were conducted...
Combined tamoxifen and luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist alone in premenopausal advanced breast cancer: a meta-analysis of four randomized trialsJ G Klijn
Dr Daniel den Hoed Kliniek and University Hospital, Rotterdam, The Netherlands
J Clin Oncol 19:343-53. 2001..Therefore, if a premenopausal woman with advanced breast cancer is thought to be suitable for endocrine treatment, it is proposed that the combination of a LHRH agonist plus tamoxifen be considered as the new standard treatment...
Treatment outcome studies. pitfalls in current methods and practiceC Legrand
European Organization for Research and Treatment of Cancer, Av E Mounier 83, Box 11, B 1200 Brussels, Belgium
Eur J Cancer 38:1173-80. 2002..Most of the studies use registry data, while only a few use discharge data or data available from clinical trials...
Histological type and marker expression of the primary tumour compared with its local recurrence after breast-conserving therapy for ductal carcinoma in situN Bijker
Department of Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, CX, 1066, The Netherlands
Br J Cancer 84:539-44. 2001....
Mature results of a randomized phase II multicenter study of exemestane versus tamoxifen as first-line hormone therapy for postmenopausal women with metastatic breast cancerR Paridaens
Universitair Ziekenhuis, Gasthuisberg, Leuven, Belgium
Ann Oncol 14:1391-8. 2003..We explored the efficacy and safety of the steroidal aromatase inactivator exemestane as first-line hormonal therapy in MBC in postmenopausal women...
