Arn Mjm van den Maagdenberg

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. pmc Functional crosstalk in culture between macrophages and trigeminal sensory neurons of a mouse genetic model of migraine
    Alessia Franceschini
    Department of Neuroscience and Italian Institute of Technology Unit, International School for Advanced Studies SISSA, via Bonomea 265, Trieste, 34136, Italy
    BMC Neurosci 13:143. 2012
  2. pmc Epigenetic mechanisms in migraine: a promising avenue?
    Else Eising
    Department of Human Genetics, Leiden University Medical Centre, Einthovenweg 20, Leiden 2333 ZC, The Netherlands
    BMC Med 11:26. 2013
  3. pmc Purkinje cell-specific ablation of Cav2.1 channels is sufficient to cause cerebellar ataxia in mice
    Boyan Todorov
    Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands
    Cerebellum 11:246-58. 2012
  4. doi request reprint High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice
    Arn M J M van den Maagdenberg
    Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands
    Ann Neurol 67:85-98. 2010
  5. pmc Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model
    Aswini Gnanasekaran
    Neurobiology Sector and Italian Institute of Technology Unit, International School for Advanced Studies, Trieste, Italy
    Mol Pain 7:77. 2011

Collaborators

Detail Information

Publications5

  1. pmc Functional crosstalk in culture between macrophages and trigeminal sensory neurons of a mouse genetic model of migraine
    Alessia Franceschini
    Department of Neuroscience and Italian Institute of Technology Unit, International School for Advanced Studies SISSA, via Bonomea 265, Trieste, 34136, Italy
    BMC Neurosci 13:143. 2012
    ....
  2. pmc Epigenetic mechanisms in migraine: a promising avenue?
    Else Eising
    Department of Human Genetics, Leiden University Medical Centre, Einthovenweg 20, Leiden 2333 ZC, The Netherlands
    BMC Med 11:26. 2013
    ..Developing drugs that specifically target epigenetic mechanisms may open up exciting new avenues for the prophylactic treatment of migraine...
  3. pmc Purkinje cell-specific ablation of Cav2.1 channels is sufficient to cause cerebellar ataxia in mice
    Boyan Todorov
    Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands
    Cerebellum 11:246-58. 2012
    ..1 channels, we show that ablation of Ca(V)2.1 channels restricted to Purkinje cells is sufficient to cause cerebellar ataxia. We demonstrate that spatial ablation of Ca(V)2.1 channels may help in unraveling mechanisms of human disease...
  4. doi request reprint High cortical spreading depression susceptibility and migraine-associated symptoms in Ca(v)2.1 S218L mice
    Arn M J M van den Maagdenberg
    Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands
    Ann Neurol 67:85-98. 2010
    ..1 Ca2+ channels. In patients, the S218L CACNA1A mutation causes a dramatic hemiplegic migraine syndrome that is associated with ataxia, seizures, and severe, sometimes fatal, brain edema often triggered by only a mild head trauma...
  5. pmc Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model
    Aswini Gnanasekaran
    Neurobiology Sector and Italian Institute of Technology Unit, International School for Advanced Studies, Trieste, Italy
    Mol Pain 7:77. 2011
    ..In an attempt to understand the basic mechanisms linked to the upregulation of P2X3 receptor activity, we investigated the influence of the lipid domain of these trigeminal sensory neurons on receptor compartmentalization and function...