E F Schippers

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint A case of simultaneous primary HIV-1 and CMV infections
    Emile F Schippers
    Department of Infectious Diseases, Leiden University Medical Center, C5 P42, P O Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Virol 29:134-6. 2004
  2. pmc Preoperative apolipoprotein CI levels correlate positively with the proinflammatory response in patients experiencing endotoxemia following elective cardiac surgery
    Emile F Schippers
    Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands
    Intensive Care Med 34:1492-7. 2008
  3. ncbi request reprint TNF-alpha promoter, Nod2 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin
    Emile F Schippers
    Department of Infectious Diseases, C5 P42, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Cytokine 26:16-24. 2004
  4. ncbi request reprint [Sharp increase in the number of syphilis cases in The Netherlands: early recognition and treatment is of great importance]
    E F Schippers
    afd Infectieziekten, Leids Universitair Medisch Centrum, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 148:1221-6. 2004
  5. ncbi request reprint IL-10 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin
    Emile F Schippers
    Department of Infectious Diseases, C5 P42, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Cytokine 29:215-28. 2005
  6. ncbi request reprint Oral valganciclovir as pre-emptive therapy has similar efficacy on cytomegalovirus DNA load reduction as intravenous ganciclovir in allogeneic stem cell transplantation recipients
    P L J van der Heiden
    Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands
    Bone Marrow Transplant 37:693-8. 2006
  7. ncbi request reprint Contrast echocardiography as a useful additional diagnostic tool in evaluating a primary cardiac tumor
    M C P Haverkamp
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, P O Box 9600, 2300 RC, Leiden, The Netherlands
    Eur J Echocardiogr 6:388-91. 2005
  8. ncbi request reprint [A case of diphtheria in the Netherlands due to an infection with Corynebacterium ulcerans]
    A P van Dam
    Klinisch Microbiologisch Laboratorium, Leids Universitair Medisch Centrum, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 147:403-6. 2003
  9. ncbi request reprint [How to treat a patient with indications for an infectious viral hemorrhagic fever]
    L G Visser
    Leids Universitair Medisch Centrum, afd Infectieziekten, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 146:2183-8. 2002
  10. ncbi request reprint [Linezolid, an agent from a new class of antibiotics]
    E J Kuijper
    Afd Medische Microbiologie, Leids Universitair Medisch Centrum, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 148:1577-81. 2004

Collaborators

Detail Information

Publications16

  1. ncbi request reprint A case of simultaneous primary HIV-1 and CMV infections
    Emile F Schippers
    Department of Infectious Diseases, Leiden University Medical Center, C5 P42, P O Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Virol 29:134-6. 2004
  2. pmc Preoperative apolipoprotein CI levels correlate positively with the proinflammatory response in patients experiencing endotoxemia following elective cardiac surgery
    Emile F Schippers
    Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands
    Intensive Care Med 34:1492-7. 2008
    ..We studied in patients undergoing cardiopulmonary bypass surgery (CPB) and experiencing endotoxemia during reperfusion whether plasma apoCI levels correlate with the inflammatory response and perioperative cytokine release...
  3. ncbi request reprint TNF-alpha promoter, Nod2 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin
    Emile F Schippers
    Department of Infectious Diseases, C5 P42, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Cytokine 26:16-24. 2004
    ..This suggests that in this model of natural LPS release, the variation between individuals in TNF-alpha release can only modestly be determined by genetic background (TNF-alpha promoter, Nod2 and TLR4) of the individual...
  4. ncbi request reprint [Sharp increase in the number of syphilis cases in The Netherlands: early recognition and treatment is of great importance]
    E F Schippers
    afd Infectieziekten, Leids Universitair Medisch Centrum, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 148:1221-6. 2004
    ....
  5. ncbi request reprint IL-10 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin
    Emile F Schippers
    Department of Infectious Diseases, C5 P42, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Cytokine 29:215-28. 2005
    ..The contribution to the inter-individual variation, however, is limited since the variation between individuals in LPS sensitivity and IL-10 production capacity can only partly be attributed to these IL-10 promoter polymorphisms...
  6. ncbi request reprint Oral valganciclovir as pre-emptive therapy has similar efficacy on cytomegalovirus DNA load reduction as intravenous ganciclovir in allogeneic stem cell transplantation recipients
    P L J van der Heiden
    Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands
    Bone Marrow Transplant 37:693-8. 2006
    ..Oral valganciclovir is an attractive and safe alternative for pre-emptive CMV treatment in T-cell-depleted allo-SCT recipients...
  7. ncbi request reprint Contrast echocardiography as a useful additional diagnostic tool in evaluating a primary cardiac tumor
    M C P Haverkamp
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, P O Box 9600, 2300 RC, Leiden, The Netherlands
    Eur J Echocardiogr 6:388-91. 2005
    ....
  8. ncbi request reprint [A case of diphtheria in the Netherlands due to an infection with Corynebacterium ulcerans]
    A P van Dam
    Klinisch Microbiologisch Laboratorium, Leids Universitair Medisch Centrum, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 147:403-6. 2003
    ..Either Corynebacterium diphtheriae or C. ulcerans could be the pathogen responsible...
  9. ncbi request reprint [How to treat a patient with indications for an infectious viral hemorrhagic fever]
    L G Visser
    Leids Universitair Medisch Centrum, afd Infectieziekten, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 146:2183-8. 2002
    ..Using this approach it is possible to diagnose high-risk patients in good time and to take appropriate measures...
  10. ncbi request reprint [Linezolid, an agent from a new class of antibiotics]
    E J Kuijper
    Afd Medische Microbiologie, Leids Universitair Medisch Centrum, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 148:1577-81. 2004
    ..Resistance to the new agent was reported rather quickly after the introduction of linezolid...
  11. ncbi request reprint [A man with fatal Lassa fever following a stay in Sierra Leone]
    P J Veldkamp
    Leids Universitair Medisch Centrum, afd Infectieziekten, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 146:2201-4. 2002
    ..Recently, a reverse transcriptase polymerase chain reaction (RT-PCR) has become available for the rapid diagnosis of acute Lassa fever, which was implemented to diagnose this patient...
  12. ncbi request reprint Similar reduction of cytomegalovirus DNA load by oral valganciclovir and intravenous ganciclovir on pre-emptive therapy after renal and renal-pancreas transplantation
    Joyant S Kalpoe
    Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands
    Antivir Ther 10:119-23. 2005
    ..In this observational study, the efficacy of the new oral prodrug valganciclovir was compared with iv ganciclovir...
  13. ncbi request reprint Cytokine response to endotoxin in individuals heterozygous for the Delta32 mutation of chemokine receptor CCR5
    Michael Heesen
    Department of Anesthesia, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1100 DD Amsterdam, The Netherlands
    Cytokine 21:195-9. 2003
    ..Our results indicate that heterozygosity for the 32bp deletion of CCR5 is not associated with an altered cytokine response to endotoxin or to a major surgical trauma when compared with individuals homozygous for the wild-type allele...
  14. ncbi request reprint No effect of preoperative selective gut decontamination on endotoxemia and cytokine activation during cardiopulmonary bypass: a randomized, placebo-controlled study
    Hens Bouter
    Department of Infectious Diseases, Leiden University Medical Center, The Netherlands
    Crit Care Med 30:38-43. 2002
    ..To a large extent, free endotoxin in the gut is a product of the proliferation of aerobic gram-negative bacteria and may be reduced by nonabsorbable antibiotics...
  15. ncbi request reprint Pharmacokinetics of once-daily lopinavir/ritonavir and the influence of dose modifications
    Charles J L la Porte
    Department of Clinical Pharmacy, Radboud University Medical Centre, Nijmegen, The Netherlands
    AIDS 19:1105-7. 2005
    ..Dose modifications in four patients with Ctrough levels less than 1.0 mg/l succeeded in only one patient. Therapeutic drug monitoring can identify patients with lower-than-expected lopinavir exposure in a larger study...
  16. ncbi request reprint Apolipoprotein CI stimulates the response to lipopolysaccharide and reduces mortality in gram-negative sepsis
    Jimmy F P Berbee
    Department of Biomedical Research, TNO Quality of Life, Leiden, The Netherlands
    FASEB J 20:2162-4. 2006
    ....