E Sarton

Summary

Affiliation: Leiden University
Country: The Netherlands

Publications

  1. ncbi Sex differences in morphine-induced ventilatory depression reside within the peripheral chemoreflex loop
    E Sarton
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 90:1329-38. 1999
  2. ncbi Response surface modeling of alfentanil-sevoflurane interaction on cardiorespiratory control and bispectral index
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 94:982-91. 2001
  3. ncbi Opioid effect on breathing frequency and thermogenesis in mice lacking exon 2 of the mu-opioid receptor gene
    E Sarton
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Adv Exp Med Biol 499:399-404. 2001
  4. ncbi Buprenorphine induces ceiling in respiratory depression but not in analgesia
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center PO Box 9600, 2300 RC Leiden, The Netherlands
    Br J Anaesth 96:627-32. 2006
  5. ncbi The involvement of the mu-opioid receptor in ketamine-induced respiratory depression and antinociception
    E Sarton
    Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands
    Anesth Analg 93:1495-500, table of contents. 2001
  6. ncbi Comparison of morphine-6-glucuronide and morphine on respiratory depressant and antinociceptive responses in wild type and mu-opioid receptor deficient mice
    R Romberg
    Department of Anesthesiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Br J Anaesth 91:862-70. 2003
  7. ncbi Speed of onset and offset and mechanisms of ventilatory depression from sevoflurane: an experimental study in the cat
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 90:1119-28. 1999
  8. ncbi Sex-related differences in the influence of morphine on ventilatory control in humans
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 88:903-13. 1998
  9. ncbi Ventilatory response to hypoxia in humans. Influences of subanesthetic desflurane
    A Dahan
    Department of Anesthesiology, Leiden University Hospital, The Netherlands
    Anesthesiology 85:60-8. 1996
  10. ncbi Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands
    Br J Anaesth 94:825-34. 2005

Collaborators

Detail Information

Publications13

  1. ncbi Sex differences in morphine-induced ventilatory depression reside within the peripheral chemoreflex loop
    E Sarton
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 90:1329-38. 1999
    ..This study gathers information in humans on the sites of sex-related differences in ventilatory depression caused by the mu-opioid receptor agonist morphine...
  2. ncbi Response surface modeling of alfentanil-sevoflurane interaction on cardiorespiratory control and bispectral index
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 94:982-91. 2001
    ..The authors examined the influence of the combined administration of sevoflurane and alfentanil on ventilatory control, heart rate (HR), and Bispectral Index (BIS) in healthy volunteers...
  3. ncbi Opioid effect on breathing frequency and thermogenesis in mice lacking exon 2 of the mu-opioid receptor gene
    E Sarton
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Adv Exp Med Biol 499:399-404. 2001
  4. ncbi Buprenorphine induces ceiling in respiratory depression but not in analgesia
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center PO Box 9600, 2300 RC Leiden, The Netherlands
    Br J Anaesth 96:627-32. 2006
    ..The aim of the study was to compare buprenorphine's behaviour with respect to the occurrence of ceiling (or apparent maximum) in these typical micro-opioid protein-(MOP) receptor effects...
  5. ncbi The involvement of the mu-opioid receptor in ketamine-induced respiratory depression and antinociception
    E Sarton
    Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands
    Anesth Analg 93:1495-500, table of contents. 2001
    ....
  6. ncbi Comparison of morphine-6-glucuronide and morphine on respiratory depressant and antinociceptive responses in wild type and mu-opioid receptor deficient mice
    R Romberg
    Department of Anesthesiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Br J Anaesth 91:862-70. 2003
    ..The influence of M6G on respiratory and antinociceptive responses was investigated in mice lacking the micro -opioid receptor (MOR) and compared with morphine...
  7. ncbi Speed of onset and offset and mechanisms of ventilatory depression from sevoflurane: an experimental study in the cat
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 90:1119-28. 1999
    ..To learn more about the mechanisms of sevoflurane-induced respiratory depression, the authors also studied its influence on the dynamic ventilatory response to carbon dioxide...
  8. ncbi Sex-related differences in the influence of morphine on ventilatory control in humans
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 88:903-13. 1998
    ..Opiate agonists have different analgesic effects in male and female patients. The authors describe the influence of sex on the respiratory pharmacology of the mu-receptor agonist morphine...
  9. ncbi Ventilatory response to hypoxia in humans. Influences of subanesthetic desflurane
    A Dahan
    Department of Anesthesiology, Leiden University Hospital, The Netherlands
    Anesthesiology 85:60-8. 1996
    ..In the current study, the influence of subanesthetic desflurane (0.1 minimum alveolar concentration [MAC]) on the isocapnic hypoxic ventilatory response was assessed in healthy volunteers during normocapnia and hypercapnia...
  10. ncbi Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands
    Br J Anaesth 94:825-34. 2005
    ..To study whether an apparent ceiling effect exists for respiratory depression induced by buprenorphine, we compared the respiratory effects of buprenorphine and fentanyl in humans and rats...
  11. ncbi Respiratory sites of action of propofol: absence of depression of peripheral chemoreflex loop by low-dose propofol
    D Nieuwenhuijs
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 95:889-95. 2001
    ..In contrast to low-dose inhalational anesthetics, the peripheral chemoreflex loop, when stimulated with carbon dioxide, remains unaffected by propofol...
  12. ncbi Anesthetic potency and influence of morphine and sevoflurane on respiration in mu-opioid receptor knockout mice
    A Dahan
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 94:824-32. 2001
    ..The involvement of the mu-opioid receptor (muOR) system in the control of breathing, anesthetic potency, and morphine- and anesthesia-induced respiratory depression was investigated in mice lacking the muOR...
  13. doi Influence of ketamine and morphine on descending pain modulation in chronic pain patients: a randomized placebo-controlled cross-over proof-of-concept study
    M Niesters
    Department of Anesthesiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Br J Anaesth 110:1010-6. 2013
    ..Dysfunction is associated with various chronic pain states. Here, the effect of ketamine and morphine on descending inhibition is examined using the conditioned pain modulation (CPM) paradigm in chronic neuropathic pain patients...