Research Topics
| Anna H RoukensSummaryAffiliation: Leiden University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Elderly subjects have a delayed antibody response and prolonged viraemia following yellow fever vaccination: a prospective controlled cohort studyAnna H Roukens
Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands
PLoS ONE 6:e27753. 2011..The mechanism of these SAEs is poorly understood. Older age has been identified as a risk factor. We tested the hypothesis that the humoral immune response to yellow fever vaccine develops more slowly in elderly than in younger subjects...
Performance of self-diagnosis and standby treatment of malaria in international oilfield service employees in the fieldAnna H Roukens
Infectious Diseases, Leiden University Medical Center LUMC, 2300 RC, Leiden, The Netherlands
Malar J 7:128. 2008..Compliance to preventive strategies is poor in travellers, especially business travellers, expatriates and long-term travellers...
Reduced intradermal test dose of yellow fever vaccine induces protective immunity in individuals with egg allergyAnna H Roukens
Dept of Infectious Diseases, Leiden University Medical Center, The Netherlands
Vaccine 27:2408-9. 2009..Intradermal injection of 1/5th dose of the yellow fever vaccine appears to be sufficient, in non-allergic as well as allergic persons, and non-inferior to the subcutaneous full dose...
Intradermal hepatitis B vaccination in non-responders after topical application of imiquimod (Aldara)Anna H Roukens
Department of Infectious Diseases, Leiden University Medical Center, The Netherlands
Vaccine 28:4288-93. 2010..We investigated the immune response to intradermal hepatitis B vaccination after pre-treatment of the skin with the TLR7 agonist imiquimod...
Hepatitis B vaccination strategy in vaccine low and non-responders: a matter of quantity of quality?Anna H Roukens
Department of Infectious Diseases, Leiden University Medical Centre, Leiden, The Netherlands
Hum Vaccin 7:654-7. 2011..In this commentary we focus on the possible biological mechanisms of hepatitis B vaccine unresponsiveness, and give practical advice to overcome this unresponsiveness...
Intradermally administered yellow fever vaccine at reduced dose induces a protective immune response: a randomized controlled non-inferiority trialAnna H Roukens
Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands
PLoS ONE 3:e1993. 2008..Implementation of yellow fever vaccination is currently hampered by limited supply of vaccine. An alternative route of administration with reduced amounts of vaccine but without loss of vaccine efficacy would boost vaccination programmes...
Yellow fever vaccine: past, present and futureAnna H Roukens
Leiden University Medical Center, Department of Infectious Diseases, Leiden, Netherlands
Expert Opin Biol Ther 8:1787-95. 2008....
Symptoms of infectious diseases in travelers with diabetes mellitus: a prospective study with matched controlsGijs G Baaten
Department of Infectious Diseases, Public Health Service GGD Amsterdam, Amsterdam, The Netherlands
J Travel Med 17:256-63. 2010..Evidence for this is needed. This study evaluates whether travelers with diabetes are at increased risk of symptomatic infectious diseases...
