Karin Roelofs

Summary

Affiliation: Leiden University
Country: The Netherlands

Publications

  1. ncbi Facing freeze: social threat induces bodily freeze in humans
    Karin Roelofs
    Department of Clinical, Health and Neuropsychology, Leiden University Institute for Psychological Research, Leiden, The Netherlands
    Psychol Sci 21:1575-81. 2010
  2. ncbi Trauma and medically unexplained symptoms towards an integration of cognitive and neuro-biological accounts
    Karin Roelofs
    Section of Clinical and Health Psychology, Leiden University, The Netherlands
    Clin Psychol Rev 27:798-820. 2007
  3. ncbi Gaze direction differentially affects avoidance tendencies to happy and angry faces in socially anxious individuals
    Karin Roelofs
    Leiden University Institute for Psychological Research, Clinical Psychology Unit, The Netherlands
    Behav Res Ther 48:290-4. 2010
  4. pmc On the neural control of social emotional behavior
    Karin Roelofs
    Leiden University Institute for Psychological Research, Clinical, Health and Neuropsychology Unit, Leiden University, The Netherlands
    Soc Cogn Affect Neurosci 4:50-8. 2009
  5. ncbi The effects of social stress and cortisol responses on the preconscious selective attention to social threat
    Karin Roelofs
    Section Clinical and Health Psychology, University of Leiden, PO Box 9555, 2300 RB Leiden, The Netherlands
    Biol Psychol 75:1-7. 2007
  6. doi Hypothalamus-pituitary-adrenal axis hyperresponsiveness is associated with increased social avoidance behavior in social phobia
    Karin Roelofs
    Clinical Psychology Unit, Leiden University Institute for Psychological Research, The Netherlands
    Biol Psychiatry 65:336-43. 2009
  7. ncbi Hyperactive action monitoring during motor-initiation in conversion paralysis: an event-related potential study
    Karin Roelofs
    Section Clinical and Health Psychology, University of Leiden, P O Box 9555, 2300 RB Leiden, The Netherlands
    Biol Psychol 71:316-25. 2006
  8. ncbi The effects of stress-induced cortisol responses on approach-avoidance behavior
    Karin Roelofs
    Section of Clinical and Health Psychology, University of Leiden, P O Box 9555, 2300 RB Leiden, The Netherlands
    Psychoneuroendocrinology 30:665-77. 2005
  9. ncbi Hypnotic susceptibility in patients with conversion disorder
    Karin Roelofs
    Department of Clinical Psychology and Personality, University of Nijmegen, The Netherlands
    J Abnorm Psychol 111:390-5. 2002
  10. ncbi Childhood abuse in patients with conversion disorder
    Karin Roelofs
    Department of Clinical and Health Psychology, University of Leiden, Leiden The Netherlands
    Am J Psychiatry 159:1908-13. 2002

Detail Information

Publications37

  1. ncbi Facing freeze: social threat induces bodily freeze in humans
    Karin Roelofs
    Department of Clinical, Health and Neuropsychology, Leiden University Institute for Psychological Research, Leiden, The Netherlands
    Psychol Sci 21:1575-81. 2010
    ..These findings open avenues for studying human freeze responses in relation to various sociobiological markers and social-affective disorders...
  2. ncbi Trauma and medically unexplained symptoms towards an integration of cognitive and neuro-biological accounts
    Karin Roelofs
    Section of Clinical and Health Psychology, Leiden University, The Netherlands
    Clin Psychol Rev 27:798-820. 2007
    ..The final purpose of the present paper was, therefore, to review current neurobiological studies focused on trauma and MUS and to formulate a research agenda to integrate these neurobiological developments with cognitive models for MUS...
  3. ncbi Gaze direction differentially affects avoidance tendencies to happy and angry faces in socially anxious individuals
    Karin Roelofs
    Leiden University Institute for Psychological Research, Clinical Psychology Unit, The Netherlands
    Behav Res Ther 48:290-4. 2010
    ....
  4. pmc On the neural control of social emotional behavior
    Karin Roelofs
    Leiden University Institute for Psychological Research, Clinical, Health and Neuropsychology Unit, Leiden University, The Netherlands
    Soc Cogn Affect Neurosci 4:50-8. 2009
    ....
  5. ncbi The effects of social stress and cortisol responses on the preconscious selective attention to social threat
    Karin Roelofs
    Section Clinical and Health Psychology, University of Leiden, PO Box 9555, 2300 RB Leiden, The Netherlands
    Biol Psychol 75:1-7. 2007
    ..Our findings are in line with previous studies in both animals and humans, that associate high glucocorticoid stress-responsiveness with diminished avoidance and prolonged freezing reactions during stress...
  6. doi Hypothalamus-pituitary-adrenal axis hyperresponsiveness is associated with increased social avoidance behavior in social phobia
    Karin Roelofs
    Clinical Psychology Unit, Leiden University Institute for Psychological Research, The Netherlands
    Biol Psychiatry 65:336-43. 2009
    ..We investigated whether increased cortisol stress-responsiveness is linked to increased social avoidance behavior in patients with social anxiety disorder (SAD)...
  7. ncbi Hyperactive action monitoring during motor-initiation in conversion paralysis: an event-related potential study
    Karin Roelofs
    Section Clinical and Health Psychology, University of Leiden, P O Box 9555, 2300 RB Leiden, The Netherlands
    Biol Psychol 71:316-25. 2006
    ..This study is the first to present electrophysiological correlates of action monitoring in CP and suggests ACC to be hyperactive when movements with affected arms are to be initiated...
  8. ncbi The effects of stress-induced cortisol responses on approach-avoidance behavior
    Karin Roelofs
    Section of Clinical and Health Psychology, University of Leiden, P O Box 9555, 2300 RB Leiden, The Netherlands
    Psychoneuroendocrinology 30:665-77. 2005
    ..These findings may have important implications for the study of freezing and avoidance reactions in patients with anxiety disorders, such as social phobia and post-traumatic stress disorder...
  9. ncbi Hypnotic susceptibility in patients with conversion disorder
    Karin Roelofs
    Department of Clinical Psychology and Personality, University of Nijmegen, The Netherlands
    J Abnorm Psychol 111:390-5. 2002
    ..These results provide the first evidence of a relationship between hypnotic susceptibility and the presence and number of conversion symptoms...
  10. ncbi Childhood abuse in patients with conversion disorder
    Karin Roelofs
    Department of Clinical and Health Psychology, University of Leiden, Leiden The Netherlands
    Am J Psychiatry 159:1908-13. 2002
    ..The present study examined this relation and investigated whether hypnotic susceptibility mediates the relation between trauma and conversion symptoms, as suggested by Janet's autohypnosis theory of conversion disorder...
  11. doi Cortisol-induced enhancement of emotional face processing in social phobia depends on symptom severity and motivational context
    Jacobien M van Peer
    Leiden University Institute for Psychological Research, Department of Clinical, Health and Neuropsychology, Leiden University, PO Box 9555, 2300 RB Leiden, The Netherlands
    Biol Psychol 81:123-30. 2009
    ..Apparently the cortisol-induced increase in processing of angry faces in SAD depends on symptom severity and motivational context...
  12. doi Psychophysiological evidence for cortisol-induced reduction in early bias for implicit social threat in social phobia
    Jacobien M van Peer
    Leiden University Institute for Psychological Research, Department of Clinical, Health and Neuropsychology, Leiden University, PO Box 9555, 2300 RB Leiden, The Netherlands
    Psychoneuroendocrinology 35:21-32. 2010
    ....
  13. ncbi The impact of early trauma and recent life-events on symptom severity in patients with conversion disorder
    Karin Roelofs
    Section of Clinical and Health Psychology, Leiden University, The Netherlands
    J Nerv Ment Dis 193:508-14. 2005
    ..The findings imply that conversion symptoms may be elicited by a complex of early and later negative life events and that traditional unifactorial trauma-theories of conversion disorder should be replaced by multifactorial stress models...
  14. ncbi Diminished cortisol responses to psychosocial stress associated with lifetime adverse events a study among healthy young subjects
    Bernet M Elzinga
    Department of Clinical, Health and Neuropsychology, University of Leiden, Wassenaarseweg 52, 2333 AK Leiden, The Netherlands
    Psychoneuroendocrinology 33:227-37. 2008
    ..The aim of the present study was to investigate the role of adverse events in childhood on cortisol reactivity to psychosocial stress in young healthy subjects (n=80)...
  15. ncbi The effects of cortisol administration on approach-avoidance behavior: an event-related potential study
    Jacobien M van Peer
    Department of Clinical, Health and Neuropsychology, Leiden University, Leiden, The Netherlands
    Biol Psychol 76:135-46. 2007
    ..Together, these results suggest a context-specific effect of cortisol on processing of, and adaptive responses to, motivationally significant threat stimuli, particularly in participants highly sensitive to threat signals...
  16. doi The role of childhood abuse in HPA-axis reactivity in Social Anxiety Disorder: a pilot study
    Bernet M Elzinga
    Leiden University Institute for Psychological Research, Clinical Psychology Unit, Leiden, The Netherlands
    Biol Psychol 83:1-6. 2010
    ..The aim of this study was to investigate whether CA is associated with enhanced cortisol reactivity to psychosocial stress in Social Anxiety Disorder (SAD)...
  17. doi Salivary testosterone: associations with depression, anxiety disorders, and antidepressant use in a large cohort study
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Psychosom Res 72:205-13. 2012
    ..The use of selective serotonin reuptake inhibitors (SSRIs) and other antidepressants is associated with sexual side effects, warranting testing for interactions with testosterone...
  18. doi Neuroticism modulates amygdala-prefrontal connectivity in response to negative emotional facial expressions
    Henk R Cremers
    Institute for Psychological Research, Clinical, Health and Neuropsychology Unit, Leiden University, Wassenaarseweg 52, Leiden, The Netherlands
    Neuroimage 49:963-70. 2010
    ..These connectivity patterns might be associated with vulnerability to developing affective disorders such as depression and anxiety...
  19. ncbi Trauma and dissociation in conversion disorder and chronic pelvic pain
    Philip Spinhoven
    Faculty of Social and Behavioral Sciences, Section of Clinical and Health Psychology, Leiden University, The Netherlands
    Int J Psychiatry Med 34:305-18. 2004
    ....
  20. doi The effects of neuroticism, extraversion, and positive and negative life events on a one-year course of depressive symptoms in euthymic previously depressed patients versus healthy controls
    Philip Spinhoven
    Institute of Psychology, Leiden University, Wassenaarseweg 52, Leiden, The Netherlands
    J Nerv Ment Dis 199:684-9. 2011
    ..The impact of life events on symptom course was not moderated by history of depression or personality traits. The effect of extraversion on symptom course was partly caused by differential engagement in positive life events...
  21. doi The specificity of childhood adversities and negative life events across the life span to anxiety and depressive disorders
    Philip Spinhoven
    Institute of Psychology, Leiden University, Leiden, The Netherlands
    J Affect Disord 126:103-12. 2010
    ..Few studies have investigated whether clustering of life adversities or comorbidity of psychiatric disorders critically influence these relationships...
  22. doi Basal cortisol is positively correlated to threat vigilance in patients with psychogenic nonepileptic seizures
    Patricia Bakvis
    Unit of Clinical Health and Neuropsychology, Institute of Psychology Research, Leiden University, Leiden, The Netherlands
    Epilepsy Behav 16:558-60. 2009
    ..These findings provide the first evidence linking an endocrine stress marker to increased threat sensitivity in PNES and support new integrated psychoneurobiological models of PNES...
  23. ncbi Aversive life events enhance human freezing responses
    Muriel A Hagenaars
    Department of Clinical Health and Neuropsychology, Leiden University, P O Box 9555, Leiden 2300 RB, The Netherlands
    J Exp Psychol Gen 141:98-105. 2012
    ..The experimental paradigm presented is a promising method to study freezing as a primary defense response in trauma-related disorders...
  24. pmc Extraversion is linked to volume of the orbitofrontal cortex and amygdala
    Henk Cremers
    Institute for Psychological Research, Clinical, Health and Neuropsychology Unit, Leiden University, Leiden, The Netherlands
    PLoS ONE 6:e28421. 2011
    ....
  25. ncbi Motor initiation and execution in patients with conversion paralysis
    Karin Roelofs
    Department of Clinical Psychology and Personality, University of Nijmegen, The Netherlands
    Acta Psychol (Amst) 110:21-34. 2002
    ..It was concluded that conversion paralysis is associated with a specific impairment in the explicit initiation of processes with a spatial and motor component...
  26. ncbi Motor imagery during hypnotic arm paralysis in high and low hypnotizable subjects
    Karin Roelofs
    Department of Clinical Psychology and Personality, University of Nijmegen, The Netherlands
    Int J Clin Exp Hypn 50:51-66. 2002
    ..These preliminary findings suggest that the motor imagery impairment observed in conversion paralysis can be induced in highs using hypnosis...
  27. doi Psychological features of patients with complex regional pain syndrome type I related dystonia
    Wouter B Reedijk
    Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 23:1551-9. 2008
    ..Although the psychological profile of the patients with CRPS-I-related dystonia shows some elevations, there does not seem to be a unique disturbed psychological profile on a group level...
  28. doi Cortisol administration enhances the coupling of midfrontal delta and beta oscillations
    Jacobien M van Peer
    Department of Clinical, Health and Neuropsychology, Leiden University, PO Box 9555, 2300 RB Leiden, The Netherlands
    Int J Psychophysiol 67:144-50. 2008
    ..These results suggest that cortisol can modify brain activity, increasing a pattern associated with anxiety and behavioral inhibition. This is in line with findings associating cortisol with behavioral inhibition and anxiety...
  29. ncbi Cortisol-induced impairments of working memory require acute sympathetic activation
    Bernet M Elzinga
    Section of Clinical and Health Psychology, University of Leiden, Leiden, Netherlands
    Behav Neurosci 119:98-103. 2005
    ..These findings suggest that adrenergic activation is essential for the impairing effects of stress-induced cortisol on working memory...
  30. doi Effects of single cortisol administrations on human affect reviewed: Coping with stress through adaptive regulation of automatic cognitive processing
    Peter Putman
    Department of Psychology, Leiden University, The Netherlands
    Psychoneuroendocrinology 36:439-48. 2011
    ..Limitations in the existing literature and suggestions for future directions are briefly discussed...
  31. doi Social anxiety and cognitive expectancy of aversive outcome in avoidance conditioning
    Verena Ly
    Leiden University Institute for Psychological Research, Clinical Health and Neuropsychology Unit, Leiden, The Netherlands
    Behav Res Ther 47:840-7. 2009
    ..Together, these findings support the role of cognitive processes in avoidance conditioning and underscore the relevance to encounter avoidance learning when studying social anxiety...
  32. ncbi Alleviating social avoidance: effects of single dose testosterone administration on approach-avoidance action
    Dorien Enter
    Leiden University, Institute of Psychology, Leiden, The Netherlands Radboud University Nijmegen, Behavioural Science Institute, Nijmegen, The Netherlands Electronic address
    Horm Behav 65:351-4. 2014
    ..These findings further the understanding of the neuroendocrine regulation of social motivational behavior and may have direct treatment implications for social anxiety, characterized by persistent social avoidance. ..
  33. doi Reduced serotonin transporter availability decreases prefrontal control of the amygdala
    Inge Volman
    Behavioural Science Institute, Radboud University Nijmegen, 6525 HR Nijmegen, The Netherlands
    J Neurosci 33:8974-9. 2013
    ..Increased amygdala activity in s-carriers originates from reduced prefrontal inhibitory regulation when social emotional behavior needs to be controlled, suggesting a mechanism for increased vulnerability to psychopathologies...
  34. ncbi Changes in PTSD patients' narratives during prolonged exposure therapy: a replication and extension
    Agnes van Minnen
    Department of Clinical Psychology and Personality, University of Nijmegen, The Netherlands
    J Trauma Stress 15:255-8. 2002
    ..Although previous results were partly replicated, it is concluded that narrative changes may be due to exposure treatment itself rather than to changes in memory representation...
  35. doi Motor imagery: a window into the mechanisms and alterations of the motor system
    Floris P de Lange
    F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Nijmegen, Netherlands
    Cortex 44:494-506. 2008
    ..The increased self-monitoring evoked by explicit motor imagery can have profound cerebral consequences in a psychopathological condition...
  36. ncbi Increased self-monitoring during imagined movements in conversion paralysis
    Floris P de Lange
    F C Donders Centre for Cognitive Neuroimaging, Radboud University Nijmegen, Kapittelweg 29, 6500 HB Nijmegen, The Netherlands
    Neuropsychologia 45:2051-8. 2007
    ..These findings lend support to the hypothesis that conversion paralysis is associated with heightened self-monitoring during actions with the affected arm...
  37. ncbi Motor and sensory dissociative phenomena associated with induced catalepsy: A brief communication
    Muriel A Hagenaars
    Department of Clinical Psychology, Radboud University Nijmegen, The Netherlands
    Int J Clin Exp Hypn 54:234-44. 2006
    ..In conclusion, catalepsy induction elicits a variety of dissociative symptoms and provides a useful research paradigm for the study of motor-perceptual dissociative phenomena...