Yanina Revsin

Summary

Affiliation: Leiden University
Country: The Netherlands

Publications

  1. doi request reprint Adrenal hypersensitivity precedes chronic hypercorticism in streptozotocin-induced diabetes mice
    Yanina Revsin
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Einsteinweg 55, Leiden, The Netherlands
    Endocrinology 149:3531-9. 2008
  2. doi request reprint Glucocorticoid receptor blockade normalizes hippocampal alterations and cognitive impairment in streptozotocin-induced type 1 diabetes mice
    Yanina Revsin
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden University Medical Center, Leiden, The Netherlands
    Neuropsychopharmacology 34:747-58. 2009
  3. ncbi request reprint When glucocorticoids change from protective to harmful. Lessons from a type 1 diabetes animal model
    Yanina Revsin
    Department of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden University, The Netherlands
    Medicina (B Aires) 69:353-8. 2009
  4. ncbi request reprint Increased astrocyte reactivity in the hippocampus of murine models of type 1 diabetes: the nonobese diabetic (NOD) and streptozotocin-treated mice
    Flavia E Saravia
    Laboratory of Neuroendocrine Biochemistry, Instituto de Biologa y Medicina Experimental, Buenos Aires, Argentina
    Brain Res 957:345-53. 2002
  5. ncbi request reprint Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes
    Yanina Revsin
    Laboratory of Neuroendocrine Biochemistry, Institute of Biology and Experimental Medicine, Obligado 2490 1428 Buenos Aires, Argentina
    Brain Res 1038:22-31. 2005
  6. ncbi request reprint Hippocampal neuropathology of diabetes mellitus is relieved by estrogen treatment
    Flavia E Saravia
    Laboratory of Neuroendocrine Biochemistry, Instituto de Biología y Medicina Experimental and Department of Biochemistry, Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina
    Cell Mol Neurobiol 26:943-57. 2006

Collaborators

  • E Ronald de Kloet
  • Melly S Oitzl
  • Flavia E Saravia
  • Alejandro F De Nicola
  • Francoise Homo-Delarche
  • Juan Beauquis
  • Analia Lima
  • Paulina Roig
  • Susana L Gonzalez
  • Maria Claudia Gonzalez Deniselle

Detail Information

Publications6

  1. doi request reprint Adrenal hypersensitivity precedes chronic hypercorticism in streptozotocin-induced diabetes mice
    Yanina Revsin
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Einsteinweg 55, Leiden, The Netherlands
    Endocrinology 149:3531-9. 2008
    ..These results suggest that sensitization of the adrenal glands to ACTH rather than an increase in circulating ACTH level is the primary event leading to hypercorticism in the STZ-induced diabetes mouse model...
  2. doi request reprint Glucocorticoid receptor blockade normalizes hippocampal alterations and cognitive impairment in streptozotocin-induced type 1 diabetes mice
    Yanina Revsin
    Division of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden University Medical Center, Leiden, The Netherlands
    Neuropsychopharmacology 34:747-58. 2009
    ..These signs of neurodegeneration can be prevented and/or reversed by GR blockade with mifepristone...
  3. ncbi request reprint When glucocorticoids change from protective to harmful. Lessons from a type 1 diabetes animal model
    Yanina Revsin
    Department of Medical Pharmacology, Leiden Amsterdam Center for Drug Research, Leiden University, The Netherlands
    Medicina (B Aires) 69:353-8. 2009
    ..As an example, we discuss in this article, how the impact of excessive levels of corticosterone in a pharmacological model of type 1 diabetes can be ameliorated after a brief treatment with a GR antagonist...
  4. ncbi request reprint Increased astrocyte reactivity in the hippocampus of murine models of type 1 diabetes: the nonobese diabetic (NOD) and streptozotocin-treated mice
    Flavia E Saravia
    Laboratory of Neuroendocrine Biochemistry, Instituto de Biologa y Medicina Experimental, Buenos Aires, Argentina
    Brain Res 957:345-53. 2002
    ..In conclusion, astrocyte changes present in genetic and pharmacological models of T1D appear to reflect an adaptive process to alterations of glucose homeostasis...
  5. ncbi request reprint Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes
    Yanina Revsin
    Laboratory of Neuroendocrine Biochemistry, Institute of Biology and Experimental Medicine, Obligado 2490 1428 Buenos Aires, Argentina
    Brain Res 1038:22-31. 2005
    ..These data support the concept that uncontrolled diabetes leads to hippocampal pathology, which adjoin to changes in other brain structures such as hypothalamus and cerebral cortex...
  6. ncbi request reprint Hippocampal neuropathology of diabetes mellitus is relieved by estrogen treatment
    Flavia E Saravia
    Laboratory of Neuroendocrine Biochemistry, Instituto de Biología y Medicina Experimental and Department of Biochemistry, Faculty of Medicine, University of Buenos Aires, Buenos Aires, Argentina
    Cell Mol Neurobiol 26:943-57. 2006
    ..Studies in animal models may open up new venues for understanding the beneficial role of steroid hormones in diabetic encephalopathy...