Marlies E J Reinders

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. doi request reprint Renal ischemia-reperfusion induces a dysbalance of angiopoietins, accompanied by proliferation of pericytes and fibrosis
    Meriem Khairoun
    Dept of Nephrology, Leiden Univ Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Am J Physiol Renal Physiol 305:F901-10. 2013
  2. doi request reprint Bone marrow-derived mesenchymal stromal cells from patients with end-stage renal disease are suitable for autologous therapy
    Marlies E J Reinders
    Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands Electronic address
    Cytotherapy 15:663-72. 2013
  3. pmc Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: results of a phase I study
    Marlies E J Reinders
    Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands
    Stem Cells Transl Med 2:107-11. 2013
  4. doi request reprint The role of mesenchymal stromal cells in chronic transplant rejection after solid organ transplantation
    Marlies E J Reinders
    Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands
    Curr Opin Organ Transplant 18:44-50. 2013
  5. ncbi request reprint Multipotent mesenchymal stromal cell therapy in renal disease and kidney transplantation
    Marlies E J Reinders
    Correspondence and offprint requests to Dr Marlies E J Reinders E mail
    Nephrol Dial Transplant 25:17-24. 2010
  6. doi request reprint Acute but transient release of terminal complement complex after reperfusion in clinical kidney transplantation
    Dorottya K de Vries
    Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands
    Transplantation 95:816-20. 2013
  7. doi request reprint Interleukin-9 release from human kidney grafts and its potential protective role in renal ischemia/reperfusion injury
    Kirsten A Kortekaas
    Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, The Netherlands
    Inflamm Res 62:53-9. 2013
  8. pmc Pre-existing endothelial cell activation predicts vasoplegia after mitral valve surgery
    Kirsten A Kortekaas
    Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, Netherlands
    Interact Cardiovasc Thorac Surg 17:523-30. 2013
  9. pmc Mesenchymal stromal cells in renal ischemia/reperfusion injury
    Dorottya K de Vries
    Department of Surgery, Leiden University Medical Center, Leiden, Netherlands
    Front Immunol 3:162. 2012
  10. doi request reprint Mesenchymal stromal cell function is not affected by drugs used in the treatment of inflammatory bowel disease
    Marjolijn Duijvestein
    Department of Gastroenterology and Hepatology, Leiden University, Medical Center, Leiden, The Netherlands
    Cytotherapy 13:1066-73. 2011

Collaborators

  • Kirsten A Kortekaas
  • Martin J Hoogduijn
  • Jeffrey Damman
  • Marjolijn Duijvestein
  • Anne Christine W Vos
  • Dorottya K de Vries
  • Pieter van der Pol
  • Meriem Khairoun
  • Ton J Rabelink
  • Cees van Kooten
  • Marina D Kraaij
  • Alexander F Schaapherder
  • Gerritje E van Anken
  • Ellen Lievers
  • Ingeborg M Bajema
  • Joris I Rotmans
  • Cees Van Kooten
  • Nicole Schlagwein
  • Hetty C de Boer
  • DaniĆ«lle J van Gijlswijk
  • Jan H Lindeman
  • Anton Jan van Zonneveld
  • Alexander F M Schaapherder
  • Sandra W van der Kooij
  • Kyra A Gelderman
  • Karin Koekkoek

Detail Information

Publications11

  1. doi request reprint Renal ischemia-reperfusion induces a dysbalance of angiopoietins, accompanied by proliferation of pericytes and fibrosis
    Meriem Khairoun
    Dept of Nephrology, Leiden Univ Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Am J Physiol Renal Physiol 305:F901-10. 2013
    ..Our findings suggest that angiopoietins and pericytes play an important role in renal microvascular remodeling and development of fibrosis. ..
  2. doi request reprint Bone marrow-derived mesenchymal stromal cells from patients with end-stage renal disease are suitable for autologous therapy
    Marlies E J Reinders
    Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands Electronic address
    Cytotherapy 15:663-72. 2013
    ..We assessed whether renal failure affected the function and therapeutic potential of BM-MSCs...
  3. pmc Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: results of a phase I study
    Marlies E J Reinders
    Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands
    Stem Cells Transl Med 2:107-11. 2013
    ..Autologous BM MSC treatment in transplant recipients with subclinical rejection and IF/TA is clinically feasible and safe, and the findings are suggestive of systemic immunosuppression...
  4. doi request reprint The role of mesenchymal stromal cells in chronic transplant rejection after solid organ transplantation
    Marlies E J Reinders
    Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands
    Curr Opin Organ Transplant 18:44-50. 2013
    ....
  5. ncbi request reprint Multipotent mesenchymal stromal cell therapy in renal disease and kidney transplantation
    Marlies E J Reinders
    Correspondence and offprint requests to Dr Marlies E J Reinders E mail
    Nephrol Dial Transplant 25:17-24. 2010
    ..In this review, evidence for the renoprotective mechanisms of MSCs as well as their therapeutic possibilities and potential hazards in acute and chronic renal disease and allograft rejection is summarized...
  6. doi request reprint Acute but transient release of terminal complement complex after reperfusion in clinical kidney transplantation
    Dorottya K de Vries
    Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands
    Transplantation 95:816-20. 2013
    ..Animal studies have suggested a role for complement activation in mediating I/R injury; however, results are not unambiguous. Whether complement activation is involved in clinical I/R injury in humans is still unclear...
  7. doi request reprint Interleukin-9 release from human kidney grafts and its potential protective role in renal ischemia/reperfusion injury
    Kirsten A Kortekaas
    Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, The Netherlands
    Inflamm Res 62:53-9. 2013
    ..Interleukin (IL)-9 is a pleiotropic cytokine recently identified to be involved in various immune responses. In this study, the role of IL-9 in renal I/R injury was assessed...
  8. pmc Pre-existing endothelial cell activation predicts vasoplegia after mitral valve surgery
    Kirsten A Kortekaas
    Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, Netherlands
    Interact Cardiovasc Thorac Surg 17:523-30. 2013
    ..The pathophysiological mechanisms underlying this syndrome remain unknown. We hypothesized that this vasoplegia reflects endothelial dysfunction, either as pre-existing condition or as a consequence of the surgical procedure...
  9. pmc Mesenchymal stromal cells in renal ischemia/reperfusion injury
    Dorottya K de Vries
    Department of Surgery, Leiden University Medical Center, Leiden, Netherlands
    Front Immunol 3:162. 2012
    ..In this review, preliminary results and opportunities of MSCs in human renal I/R injury are summarized. We might be heading towards a cell-based paradigm shift in the treatment of renal I/R injury...
  10. doi request reprint Mesenchymal stromal cell function is not affected by drugs used in the treatment of inflammatory bowel disease
    Marjolijn Duijvestein
    Department of Gastroenterology and Hepatology, Leiden University, Medical Center, Leiden, The Netherlands
    Cytotherapy 13:1066-73. 2011
    ..However, little is known about MSC interactions with these immunosuppressive drugs. To address this issue we studied the combined effect of MSC and IBD drugs in in vitro functionality assays...
  11. doi request reprint Dexamethasone increases ROS production and T cell suppressive capacity by anti-inflammatory macrophages
    Marina D Kraaij
    Leiden University Medical Center, Department of Nephrology, 2300 RC Leiden, The Netherlands
    Mol Immunol 49:549-57. 2011
    ..In conclusion, we show that the anti-inflammatory drug dexamethasone increases the ROS producing capacity of macrophages...