R Natte

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. pmc MLPAinter for MLPA interpretation: an integrated approach for the analysis, visualisation and data management of Multiplex Ligation-dependent Probe Amplification
    Ronald van Eijk
    Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
    BMC Bioinformatics 11:67. 2010
  2. ncbi request reprint Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles
    R Natte
    Department of Neurology, Leiden University Medical Center, The Netherlands
    Ann Neurol 50:765-72. 2001
  3. ncbi request reprint Multiplex ligation-dependent probe amplification for the detection of 1p and 19q chromosomal loss in oligodendroglial tumors
    Remco Natté
    Department of Pathology, Leiden University Medical Center, P O Box 9600, 2300RC, Leiden, The Netherlands
    Brain Pathol 15:192-7. 2005
  4. ncbi request reprint Secondary microvascular degeneration in amyloid angiopathy of patients with hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D)
    H V Vinters
    Department of Neurology, Leiden University Medical Center, The Netherlands
    Acta Neuropathol 95:235-44. 1998
  5. ncbi request reprint Ultrastructural evidence of early non-fibrillar Abeta42 in the capillary basement membrane of patients with hereditary cerebral hemorrhage with amyloidosis, Dutch type
    R Natte
    Department of Neurology, K5Q, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Acta Neuropathol 98:577-82. 1999
  6. ncbi request reprint Amyloid beta precursor protein-mRNA is expressed throughout cerebral vessel walls
    R Natte
    Department of Neurology K5Q, Leiden University Medical Center, P O Box 9600, 2300 RC, Leiden, Netherlands
    Brain Res 828:179-83. 1999
  7. ncbi request reprint Age-related plaque morphology and C-terminal heterogeneity of amyloid beta in Dutch-type hereditary cerebral hemorrhage with amyloidosis
    M L Maat-Schieman
    Department of Neurology, Leiden University Medical Center, The Netherlands
    Acta Neuropathol 99:409-19. 2000

Collaborators

Detail Information

Publications7

  1. pmc MLPAinter for MLPA interpretation: an integrated approach for the analysis, visualisation and data management of Multiplex Ligation-dependent Probe Amplification
    Ronald van Eijk
    Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
    BMC Bioinformatics 11:67. 2010
    ..In one reaction, up to 50 different genomic sequences can be analysed. For a reliable work-flow, tools are needed for administrative support, data management, normalisation, visualisation, reporting and interpretation...
  2. ncbi request reprint Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles
    R Natte
    Department of Neurology, Leiden University Medical Center, The Netherlands
    Ann Neurol 50:765-72. 2001
    ..This may have implications for clinicopathological correlations in Alzheimer's disease and other dementias with cerebral amyloid angiopathy...
  3. ncbi request reprint Multiplex ligation-dependent probe amplification for the detection of 1p and 19q chromosomal loss in oligodendroglial tumors
    Remco Natté
    Department of Pathology, Leiden University Medical Center, P O Box 9600, 2300RC, Leiden, The Netherlands
    Brain Pathol 15:192-7. 2005
    ..We conclude that MLPA is a valid and reproducible method for the detection of 1p/19q chromosomal deletions in OGs stored on formalin fixed, paraffin embedded tissue...
  4. ncbi request reprint Secondary microvascular degeneration in amyloid angiopathy of patients with hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D)
    H V Vinters
    Department of Neurology, Leiden University Medical Center, The Netherlands
    Acta Neuropathol 95:235-44. 1998
    ..However, macrophages were prominent in the walls of such vessels and may play a role in the pathogenesis and progression of CAA-related microvasculopathy...
  5. ncbi request reprint Ultrastructural evidence of early non-fibrillar Abeta42 in the capillary basement membrane of patients with hereditary cerebral hemorrhage with amyloidosis, Dutch type
    R Natte
    Department of Neurology, K5Q, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Acta Neuropathol 98:577-82. 1999
    ..The present findings suggest that in capillaries the accumulation and subsequent polymerization of Abeta42, possibly in conjunction with basement membrane changes, precedes the definite fibril formation with Abeta40...
  6. ncbi request reprint Amyloid beta precursor protein-mRNA is expressed throughout cerebral vessel walls
    R Natte
    Department of Neurology K5Q, Leiden University Medical Center, P O Box 9600, 2300 RC, Leiden, Netherlands
    Brain Res 828:179-83. 1999
    ..The demonstration of AbetaPP-mRNA at all vascular sites where amyloid formation can occur supports an important contribution of locally derived Abeta to cerebrovascular amyloidosis...
  7. ncbi request reprint Age-related plaque morphology and C-terminal heterogeneity of amyloid beta in Dutch-type hereditary cerebral hemorrhage with amyloidosis
    M L Maat-Schieman
    Department of Neurology, Leiden University Medical Center, The Netherlands
    Acta Neuropathol 99:409-19. 2000
    ..This study suggests that HCHWA-D is a model of plaque evolution in which clouds leave fine diffuse plaques, which may become dense diffuse and ultimately coarse or homogeneous plaques...