Mary E Morgan

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis
    Mary E Morgan
    Leiden University Medical Center, Leiden, The Netherlands
    Arthritis Rheum 48:1452-60. 2003
  2. ncbi request reprint CD25+ regulatory cells from HLA-DQ8 transgenic mice are capable of modulating collagen-induced arthritis
    Mary E Morgan
    Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
    Hum Immunol 65:1319-27. 2004
  3. ncbi request reprint Effective treatment of collagen-induced arthritis by adoptive transfer of CD25+ regulatory T cells
    Mary E Morgan
    Leiden University Medical Center, Leiden, The Netherlands
    Arthritis Rheum 52:2212-21. 2005
  4. ncbi request reprint Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans
    Mary E Morgan
    Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
    Hum Immunol 66:13-20. 2005
  5. ncbi request reprint Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators
    Geertje J D van Mierlo
    Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
    J Immunol 180:2747-51. 2008
  6. ncbi request reprint Toll-like receptors on regulatory T cells: expanding immune regulation
    Roger P M Sutmuller
    Tumor Immunology Laboratory, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Trends Immunol 27:387-93. 2006

Collaborators

Detail Information

Publications6

  1. ncbi request reprint CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis
    Mary E Morgan
    Leiden University Medical Center, Leiden, The Netherlands
    Arthritis Rheum 48:1452-60. 2003
    ..We wished to evaluate their potential for influencing systemic and chronic joint inflammation by investigating their involvement in collagen-induced arthritis (CIA)...
  2. ncbi request reprint CD25+ regulatory cells from HLA-DQ8 transgenic mice are capable of modulating collagen-induced arthritis
    Mary E Morgan
    Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
    Hum Immunol 65:1319-27. 2004
    ..These results indicate that HLA-DQ8 mice contain naturally occurring CD25+ regulatory cells that modulate collagen-induced arthritis and imply that DQ8 expression does not hinder the development of CD25+ T regulatory cells...
  3. ncbi request reprint Effective treatment of collagen-induced arthritis by adoptive transfer of CD25+ regulatory T cells
    Mary E Morgan
    Leiden University Medical Center, Leiden, The Netherlands
    Arthritis Rheum 52:2212-21. 2005
    ..We undertook this study to determine whether regulatory T cells have the potential to be used therapeutically in arthritis...
  4. ncbi request reprint Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans
    Mary E Morgan
    Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
    Hum Immunol 66:13-20. 2005
    ..These results indicate that FOXP3 expression in humans, unlike mice, may not be specific for cells with a regulatory phenotype and may be only a consequence of activation status...
  5. ncbi request reprint Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators
    Geertje J D van Mierlo
    Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
    J Immunol 180:2747-51. 2008
    ..Thus, shedding of TNFRII represents a novel mechanism by which Treg cells can inhibit the action of TNF, a pivotal cytokine driving inflammation...
  6. ncbi request reprint Toll-like receptors on regulatory T cells: expanding immune regulation
    Roger P M Sutmuller
    Tumor Immunology Laboratory, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Trends Immunol 27:387-93. 2006
    ..This review examines the ramifications of TLR engagement on Treg cells and conventional T cells, and discusses the potential role of TLRs on Treg cells and the consequences for disease therapy...