R M Moison

Summary

Affiliation: Leiden University
Country: The Netherlands

Publications

  1. ncbi request reprint Topically applied eicosapentaenoic acid protects against local immunosuppression induced by UVB irradiation, cis-urocanic acid and thymidine dinucleotides
    R M Moison
    Leiden Amsterdam Center for Drug Research, Department of Medicinal Photochemistry, Leiden University, P O Box 9502, 2300 RA Leiden, The Netherlands
    Photochem Photobiol 73:64-70. 2001
  2. ncbi request reprint Dietary eicosapentaenoic acid prevents systemic immunosuppression in mice induced by UVB radiation
    R M Moison
    Department of Medicinal Photochemistry, Leiden Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
    Radiat Res 156:36-44. 2001
  3. ncbi request reprint Topical antioxidant vitamins C and E prevent UVB-radiation-induced peroxidation of eicosapentaenoic acid in pig skin
    Ralf M W Moison
    Department of Medicinal Photochemistry, Leiden Amsterdam Center for Drug Research, University of Leiden, P O Box 9502, 2300 RA Leiden, The Netherlands
    Radiat Res 157:402-9. 2002
  4. ncbi request reprint Photoprotection by antioxidants against UVB-radiation-induced damage in pig skin organ culture
    Jolanda M Rijnkels
    Department of Medicinal Photochemistry, Leiden Amsterdam Center for Drug Research, University of Leiden, P O Box 9502, 2300 RA Leiden, The Netherlands
    Radiat Res 159:210-7. 2003
  5. ncbi request reprint Topically applied vitamin C and cysteine derivatives protect against UVA-induced photodegradation of suprofen in ex vivo pigskin
    Ralf M W Moison
    Department of Medicinal Photochemistry, Leiden Amsterdam Center for Drug Research, University of Leiden, Leiden, The Netherlands
    Photochem Photobiol 77:343-8. 2003
  6. ncbi request reprint Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers
    Lesley E Rhodes
    Photobiology Unit, Dermatology Centre, University of Manchester, UK
    Carcinogenesis 24:919-25. 2003

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Topically applied eicosapentaenoic acid protects against local immunosuppression induced by UVB irradiation, cis-urocanic acid and thymidine dinucleotides
    R M Moison
    Leiden Amsterdam Center for Drug Research, Department of Medicinal Photochemistry, Leiden University, P O Box 9502, 2300 RA Leiden, The Netherlands
    Photochem Photobiol 73:64-70. 2001
    ..In conclusion, topically applied EPA protects against UVB-, cis-UCA- and pTpT-induced immunosuppression and maintenance of an adequate antioxidant defense seems to be an important prerequisite for the protective action by EPA...
  2. ncbi request reprint Dietary eicosapentaenoic acid prevents systemic immunosuppression in mice induced by UVB radiation
    R M Moison
    Department of Medicinal Photochemistry, Leiden Amsterdam Center for Drug Research, Leiden University, Leiden, The Netherlands
    Radiat Res 156:36-44. 2001
    ..The degree of protection appears to be related to the amount of EPA incorporated and the ability of the epidermis to maintain an adequate antioxidant level after irradiation...
  3. ncbi request reprint Topical antioxidant vitamins C and E prevent UVB-radiation-induced peroxidation of eicosapentaenoic acid in pig skin
    Ralf M W Moison
    Department of Medicinal Photochemistry, Leiden Amsterdam Center for Drug Research, University of Leiden, P O Box 9502, 2300 RA Leiden, The Netherlands
    Radiat Res 157:402-9. 2002
    ..The ex vivo pig skin model provides a useful tool for assessing short-term biochemical effects related to UVB radiation, without the use of living experimental animals...
  4. ncbi request reprint Photoprotection by antioxidants against UVB-radiation-induced damage in pig skin organ culture
    Jolanda M Rijnkels
    Department of Medicinal Photochemistry, Leiden Amsterdam Center for Drug Research, University of Leiden, P O Box 9502, 2300 RA Leiden, The Netherlands
    Radiat Res 159:210-7. 2003
    ..Furthermore, the ex vivo pig skin model was a useful tool for testing compounds for their antioxidant activity...
  5. ncbi request reprint Topically applied vitamin C and cysteine derivatives protect against UVA-induced photodegradation of suprofen in ex vivo pigskin
    Ralf M W Moison
    Department of Medicinal Photochemistry, Leiden Amsterdam Center for Drug Research, University of Leiden, Leiden, The Netherlands
    Photochem Photobiol 77:343-8. 2003
    ..Coapplication of these antioxidants may therefore be an effective way to reduce or prevent the phototoxic effects of SUP in vivo...
  6. ncbi request reprint Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers
    Lesley E Rhodes
    Photobiology Unit, Dermatology Centre, University of Manchester, UK
    Carcinogenesis 24:919-25. 2003
    ..e. sunburn, UVR-induced p53 in skin and strand breaks in PBL, indicate protection by dietary EPA against acute UVR-induced genotoxicity; longer-term supplementation might reduce skin cancer in humans...