M J Mertens

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Propofol alters the pharmacokinetics of alfentanil in healthy male volunteers
    M J Mertens
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 94:949-57. 2001
  2. ncbi request reprint Predictive performance of computer-controlled infusion of remifentanil during propofol/remifentanil anaesthesia
    M J Mertens
    Department of Anaesthesiology, Leiden University Medical Centre, PO Box 9600, NL 2300 RC Leiden, The Netherlands
    Br J Anaesth 90:132-41. 2003
  3. ncbi request reprint Propofol reduces perioperative remifentanil requirements in a synergistic manner: response surface modeling of perioperative remifentanil-propofol interactions
    Martijn J Mertens
    Department of Anesthesiology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands
    Anesthesiology 99:347-59. 2003
  4. ncbi request reprint Mixed-effects modeling of the influence of alfentanil on propofol pharmacokinetics
    Martijn J Mertens
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 100:795-805. 2004

Detail Information

Publications4

  1. ncbi request reprint Propofol alters the pharmacokinetics of alfentanil in healthy male volunteers
    M J Mertens
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 94:949-57. 2001
    ..The influence of propofol on the pharmacokinetics of alfentanil is poorly understood. The authors therefore studied the effect of a pseudo-steady state concentration of propofol on the pharmacokinetics of alfentanil...
  2. ncbi request reprint Predictive performance of computer-controlled infusion of remifentanil during propofol/remifentanil anaesthesia
    M J Mertens
    Department of Anaesthesiology, Leiden University Medical Centre, PO Box 9600, NL 2300 RC Leiden, The Netherlands
    Br J Anaesth 90:132-41. 2003
    ..v. anaesthesia, has not been determined in a clinical setting. We studied the predictive performance of five parameter sets of remifentanil when used for TCI of remifentanil during propofol anaesthesia in surgical patients...
  3. ncbi request reprint Propofol reduces perioperative remifentanil requirements in a synergistic manner: response surface modeling of perioperative remifentanil-propofol interactions
    Martijn J Mertens
    Department of Anesthesiology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands
    Anesthesiology 99:347-59. 2003
    ..The authors studied the effect of propofol on remifentanil requirements for suppression of responses to clinically relevant stimuli and evaluated this in relation to previously published data on propofol and alfentanil...
  4. ncbi request reprint Mixed-effects modeling of the influence of alfentanil on propofol pharmacokinetics
    Martijn J Mertens
    Department of Anesthesiology, Leiden University Medical Center, The Netherlands
    Anesthesiology 100:795-805. 2004
    ..The influence of alfentanil on the pharmacokinetics of propofol is poorly understood. Therefore, the authors studied the effect of a pseudo-steady state concentration of alfentanil on the pharmacokinetics of propofol...