Research Topics
Genomes and GenesSpecies | A H MeijerSummaryAffiliation: Leiden University Country: The Netherlands Publications
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Detail Information
Publications
Vectors for transcription factor cloning and target site identification by means of genetic selection in yeastA H Meijer
Institute of Molecular Plant Sciences, Leiden University, Clusius Laboratory, The Netherlands
Yeast 14:1407-15. 1998..Tests with Oxhox1 as transcriptional activator demonstrated the usefulness of the deprived reporter gene vector...- HD-Zip proteins of families I and II from rice: interactions and functional propertiesA H Meijer
Institute of Molecular Plant Sciences, Leiden University, Clusius Laboratory, The Netherlands
Mol Gen Genet 263:12-21. 2000..Heterodimerization across the HD-Zip families I and II apparently does not to occur... - Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infectionAnnemarie H Meijer
Institute of Biology, Leiden University, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands
Mol Immunol 42:1185-203. 2005..Since a large group of genes linked to immune responses did not show altered expression in the infected animals, these results suggest specific responses in mycobacterium-induced disease... - Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafishAnnemarie H Meijer
Institute of Biology, Leiden University, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands
Mol Immunol 40:773-83. 2004.... - MyD88 innate immune function in a zebrafish embryo infection modelAstrid M van der Sar
Institute of Biology, Leiden University, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands
Infect Immun 74:2436-41. 2006.... - Transcriptional repression by Oshox1, a novel homeodomain leucine zipper protein from riceA H Meijer
Institute of Molecular Plant Sciences, Leiden University, Clusius Laboratory, The Netherlands
Plant J 11:263-76. 1997..Repression was strictly dependent on the presence of upstream Oshox1 binding sites in the reporter gene constructs and a function of the N-terminal region of Oshox1, preceding the homeodomain... - Glucocorticoid-inducible gene expression in riceP B Ouwerkerk
Institute of Molecular Plant Sciences, Leiden University, Clusius Laboratory, The Netherlands
Planta 213:370-8. 2001..As the severity of these effects varied between different lines, we could select lines with a mild phenotype for future use as activator lines in crosses with 'target' plants... - Yeast one-hybrid screening for DNA-protein interactionsP B Ouwerkerk
Leiden University, Leiden, The Netherlands
Curr Protoc Mol Biol . 2001..The advantage of cloning transcription factors or other DNA-binding proteins via one-hybrid screenings, compared to biochemical techniques, is that the procedure does not require specific optimization of in vitro conditions... - Genomic annotation and transcriptome analysis of the zebrafish (Danio rerio) hox complex with description of a novel member, hox b 13aM Corredor-Adámez
Institute of Biology, Leiden University, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands
Evol Dev 7:362-75. 2005..We are currently characterizing this gene at the functional level. We argue that the oligo design for microarrays can be greatly enhanced by the availability of genomic sequences... - Identification and real-time imaging of a myc-expressing neutrophil population involved in inflammation and mycobacterial granuloma formation in zebrafishAnnemarie H Meijer
Institute of Biology, Leiden University, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands
Dev Comp Immunol 32:36-49. 2008..Using real-time confocal imaging we demonstrate that these cells migrate to sites of inflammation and are involved in innate immune responses towards infections, including Mycobacterium marinum-induced granuloma formation... - Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulationS F Gabby Krens
Institute of Biology, Leiden University, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands
Dev Biol 319:370-83. 2008..Together, our data define distinct roles for ERK1 and ERK2 in developmental cell migration processes during zebrafish embryogenesis... - Discovery of a functional glucocorticoid receptor beta-isoform in zebrafishMarcel J M Schaaf
Department of Molecular Cell Biology, Institute of Biology, Leiden, The Netherlands
Endocrinology 149:1591-9. 2008..Thus, for the first time, a GR beta-isoform has been identified in a nonhuman animal species, shedding new light on the relevance of this GR splice variant and providing a versatile animal model for studies on the GR system... - Genomic annotation and expression analysis of the zebrafish Rho small GTPase family during development and bacterial infectionEnrique Salas-Vidal
Institute of Biology, Leiden University, Wassenaarseweg 64, 2333 AL Leiden, The Netherlands
Genomics 86:25-37. 2005..This complete annotation study provides a firm basis for the use of zebrafish as a model for analysis of Rho GTPase function in vertebrate development and the innate immune system... - Macrophage-specific gene functions in Spi1-directed innate immunityAnna Zakrzewska
Institute of Biology, Leiden University, Leiden, The Netherlands
Blood 116:e1-11. 2010..Therefore, based on our combined transcriptome analyses, we discovered novel early macrophage-specific marker genes, including a signal transducer pivotal for macrophage migration in the innate immune response... - Zebrafish development and regeneration: new tools for biomedical researchSebastiaan A Brittijn
Institute of Biology, Dept Integrative Zoology, University of Leiden, The Netherlands
Int J Dev Biol 53:835-50. 2009..Zebrafish cannot replace mammalian models in the drug development pipeline. Nevertheless, they can provide a cost-effective bridge between cell-based assays and mammalian whole-organism models... - Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to Salmonella infectionOliver W Stockhammer
Institute of Biology, Leiden University, Leiden, The Netherlands
J Immunol 182:5641-53. 2009..Finally, we showed that induction of il1b, mmp9, and irak3 requires Myd88-dependent signaling, while ifn1 and il8 were induced Myd88 independently during Salmonella infection... - Gene expression and digit homology in the chicken embryo wingMonique C M Welten
Institute for Biology, Leiden University, Kaiserstraat 63, 2311 GP Leiden, The Netherlands
Evol Dev 7:18-28. 2005..Our study provides the first gene expression evidence for at least five digital domains in the chick wing. The failure of the first to develop may be plausibly linked to attenuation of posterior signals... - Different subcellular localization and trafficking properties of KNOX class 1 homeodomain proteins from riceSuzanne J H Kuijt
Institute of Biology, Leiden University, Wassenaarseweg 64, 2333 AL, Leiden, The Netherlands
Plant Mol Biol 55:781-96. 2004.... - Developmental regulation and downstream effects of the knox class homeobox genes Oskn2 and Oskn3 from riceA Dorien Postma-Haarsma
Institute of Molecular Plant Sciences, Leiden University, Clusius Laboratory, The Netherlands
Plant Mol Biol 48:423-41. 2002..Finally, protein-protein interactions may contribute to the functioning of KNOX proteins, as the ability of Oskn3 and Oskn2 to form heterodimers could be demonstrated... - A genome-wide survey of HD-Zip genes in rice and analysis of drought-responsive family membersAdamantia Agalou
Institute of Biology, Clusius Laboratory, Leiden University, PO Box 9505, 2300 RA, Leiden, The Netherlands
Plant Mol Biol 66:87-103. 2008..Loss-of-function analysis of Oshox4 revealed no specific phenotype, but overexpression analysis suggested a role for Oshox4 in elongation and maturation processes... - The RADICLELESS1 gene is required for vascular pattern formation in riceEnrico Scarpella
Institute of Molecular Plant Sciences, Leiden University, Clusius Laboratory, PO Box 9505, 2300 RA Leiden, The Netherlands
Development 130:645-58. 2003..ral1 is the first mutant impaired in both procambium development and vascular patterning to be isolated in a monocot species... - The procambium specification gene Oshox1 promotes polar auxin transport capacity and reduces its sensitivity toward inhibitionEnrico Scarpella
Institute of Molecular Plant Sciences, Leiden University, Clusius Laboratory, P.O. Box 9505, 2300 RA Leiden, The Netherlands
Plant Physiol 130:1349-60. 2002.... - Model systems for infectious disease and cancer in zebrafish: a report on an EMBO workshop held at the Lorentz Center, Leiden, The Netherlands, July 16-18, 2007Nikolaus Trede
Department of Pediatrics and Division of Oncological Sciences at the Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA
Zebrafish 4:287-92. 2007 - Characterization of five novel dehydration-responsive homeodomain leucine zipper genes from the resurrection plant Craterostigma plantagineumXin Deng
, , Germany
Plant Mol Biol 49:601-10. 2002..CPHB-3/4/5 were down-regulated by dehydration in both leaves and roots. The results support the role of HDZips in regulating programs of gene expression in C. plantagineum that lead to desiccation tolerance... - A homeodomain leucine zipper gene from Craterostigma plantagineum regulates abscisic acid responsive gene expression and physiological responsesXin Deng
Max Planck Institut fur Zuchtungsforschung, Carl von Linne Weg 10, Cologne D 50829, Germany
Plant Mol Biol 61:469-89. 2006..CpHB-7 gene expression is also linked to early organ development, leading to the suggestion that CpHB-7 is functionally similar to the Arabidopsis transcription factor, ATHB-6... - EU-OSTID: a collection of transposon insertional mutants for functional genomics in riceL J G van Enckevort
Plant Research International, Wageningen UR, Wageningen, The Netherlands
Plant Mol Biol 59:99-110. 2005..These FSTs and the corresponding plant lines are publicly available through OrygenesDB database and from the EU consortium members...