Rinse Klooster

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi Selection of VHH antibody fragments that recognize different Aβ depositions using complex immune libraries
    Rinse Klooster
    Department of Human and Clinical Genetics, Medical Genetics Center, Leiden University Medical Center, Leiden, The Netherlands
    Methods Mol Biol 911:241-53. 2012
  2. ncbi Comprehensive expression analysis of FSHD candidate genes at the mRNA and protein level
    Rinse Klooster
    Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
    Eur J Hum Genet 17:1615-24. 2009
  3. ncbi Self-regulated alternative splicing at the AHNAK locus
    Antoine de Morrée
    Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
    FASEB J 26:93-103. 2012
  4. ncbi Digenic inheritance of an SMCHD1 mutation and an FSHD-permissive D4Z4 allele causes facioscapulohumeral muscular dystrophy type 2
    Richard J L F Lemmers
    Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
    Nat Genet 44:1370-4. 2012
  5. ncbi Modeling oculopharyngeal muscular dystrophy in myotube cultures reveals reduced accumulation of soluble mutant PABPN1 protein
    Vered Raz
    Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
    Am J Pathol 179:1988-2000. 2011
  6. ncbi Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice
    Rinse Klooster
    Department of Human Genetics, Medical Genetics Centre, Leiden University Medical Centre, Leiden, The Netherlands
    Brain 135:1081-101. 2012

Collaborators

Detail Information

Publications6

  1. ncbi Selection of VHH antibody fragments that recognize different Aβ depositions using complex immune libraries
    Rinse Klooster
    Department of Human and Clinical Genetics, Medical Genetics Center, Leiden University Medical Center, Leiden, The Netherlands
    Methods Mol Biol 911:241-53. 2012
    ..We show that this can result in binders that preferentially recognize the target of interest when present in specific structures depending on the antigen source...
  2. ncbi Comprehensive expression analysis of FSHD candidate genes at the mRNA and protein level
    Rinse Klooster
    Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
    Eur J Hum Genet 17:1615-24. 2009
    ..The one exception was a selective increase in FRG2 mRNA expression in FSHD myotubes. This study provides further evidence that there is no demonstrable consistent, large magnitude, overexpression of any of the FSHD candidate genes...
  3. ncbi Self-regulated alternative splicing at the AHNAK locus
    Antoine de Morrée
    Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
    FASEB J 26:93-103. 2012
    ..A small 17-kDa isoform of Periaxin similarly traffics between the cytoplasm and the nucleus to regulate mRNA splicing. Thus, AHNAK constitutes a novel mechanism in post-transcriptional control of gene expression...
  4. ncbi Digenic inheritance of an SMCHD1 mutation and an FSHD-permissive D4Z4 allele causes facioscapulohumeral muscular dystrophy type 2
    Richard J L F Lemmers
    Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
    Nat Genet 44:1370-4. 2012
    ..Our study identifies SMCHD1 as an epigenetic modifier of the D4Z4 metastable epiallele and as a causal genetic determinant of FSHD2 and possibly other human diseases subject to epigenetic regulation...
  5. ncbi Modeling oculopharyngeal muscular dystrophy in myotube cultures reveals reduced accumulation of soluble mutant PABPN1 protein
    Vered Raz
    Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
    Am J Pathol 179:1988-2000. 2011
    ..We suggest that this difference can contribute to muscle weakness in OPMD...
  6. ncbi Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice
    Rinse Klooster
    Department of Human Genetics, Medical Genetics Centre, Leiden University Medical Centre, Leiden, The Netherlands
    Brain 135:1081-101. 2012
    ....