Ingrid M Jazet

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint [The thiazolidinedione derivates: a new class of oral blood glucose lowering agents]
    I M Jazet
    Leids Universitair Medisch Centrum, afd Algemene Interne Geneeskunde, Albinusdreef 2, 2333 ZA Leiden
    Ned Tijdschr Geneeskd 145:1541-7. 2001
  2. pmc Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions
    M Snel
    Departments of Endocrinology and Metabolism and General Internal Medicine, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Int J Endocrinol 2012:983814. 2012
  3. ncbi request reprint [Therapy resistant diabetes mellitus and lipodystrophy: leptin therapy leads to improvement]
    Ingrid M Jazet
    Leids Universitair Medisch Centrum, Afd Endocrinologie Algemene Interne Geneeskunde, Leiden, The Netherlands
    Ned Tijdschr Geneeskd 157:A5482. 2013
  4. ncbi request reprint [Rosiglitazone: no increase in cardiovascular mortality]
    Ingrid M Jazet
    Leids Universitair Medisch Centrum, afd Endocrinologie en Metabolisme Algemene Interne Geneeskunde, Leiden, The Netherlands
    Ned Tijdschr Geneeskd 153:A942. 2009
  5. ncbi request reprint [Measures to prevent or delay type 2 diabetes mellitus]
    I M Jazet
    Leids Universitair Medisch Centrum, afd Algemene Interne Geneeskunde, Leiden
    Ned Tijdschr Geneeskd 152:132-8. 2008
  6. ncbi request reprint Loss of 50% of excess weight using a very low energy diet improves insulin-stimulated glucose disposal and skeletal muscle insulin signalling in obese insulin-treated type 2 diabetic patients
    I M Jazet
    Department of General Internal Medicine, C4 r 73, Leiden University Medical Centre, P O Box 9600, 2300 RC Leiden, The Netherlands
    Diabetologia 51:309-19. 2008
  7. ncbi request reprint Sustained beneficial metabolic effects 18 months after a 30-day very low calorie diet in severely obese, insulin-treated patients with type 2 diabetes
    Ingrid M Jazet
    Department of General Internal Medicine, Leiden University Medical Centre, Leiden, The Netherlands
    Diabetes Res Clin Pract 77:70-6. 2007
  8. ncbi request reprint Adipose tissue as an endocrine organ: impact on insulin resistance
    I M Jazet
    Department of General Internal Medicine C1 r 45, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Neth J Med 61:194-212. 2003
  9. ncbi request reprint Effect of a 2-day very low-energy diet on skeletal muscle insulin sensitivity in obese type 2 diabetic patients on insulin therapy
    Ingrid M Jazet
    Department of General Internal Medicine C 4 66, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands
    Metabolism 54:1669-78. 2005
  10. ncbi request reprint Two days of a very low calorie diet reduces endogenous glucose production in obese type 2 diabetic patients despite the withdrawal of blood glucose-lowering therapies including insulin
    Ingrid M Jazet
    Department of General Internal Medicine, C1 r 45, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands
    Metabolism 54:705-12. 2005

Collaborators

Detail Information

Publications28

  1. ncbi request reprint [The thiazolidinedione derivates: a new class of oral blood glucose lowering agents]
    I M Jazet
    Leids Universitair Medisch Centrum, afd Algemene Interne Geneeskunde, Albinusdreef 2, 2333 ZA Leiden
    Ned Tijdschr Geneeskd 145:1541-7. 2001
    ..The thiazolidine-dione derivatives are generally well tolerated and the new drugs such as rosiglitazone and pioglitazone do not seem to be associated with idiosyncratic hepatotoxicity...
  2. pmc Ectopic fat and insulin resistance: pathophysiology and effect of diet and lifestyle interventions
    M Snel
    Departments of Endocrinology and Metabolism and General Internal Medicine, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Int J Endocrinol 2012:983814. 2012
    ..In addition, we systematically reviewed the literature for the effects of diet-induced weight loss and exercise on ectopic fat depositions...
  3. ncbi request reprint [Therapy resistant diabetes mellitus and lipodystrophy: leptin therapy leads to improvement]
    Ingrid M Jazet
    Leids Universitair Medisch Centrum, Afd Endocrinologie Algemene Interne Geneeskunde, Leiden, The Netherlands
    Ned Tijdschr Geneeskd 157:A5482. 2013
    ..3% to 1.3% in the first patient and from 20.6% to 12.4% in the second. Leptin therapy is an effective and safe treatment for therapy-resistant diabetes and hypertriglyceridemia in patients with congenital lipodystrophy...
  4. ncbi request reprint [Rosiglitazone: no increase in cardiovascular mortality]
    Ingrid M Jazet
    Leids Universitair Medisch Centrum, afd Endocrinologie en Metabolisme Algemene Interne Geneeskunde, Leiden, The Netherlands
    Ned Tijdschr Geneeskd 153:A942. 2009
    ..Therefore, rosiglitazone can be prescribed as long as the indications are followed and the patients concerned do not have heart failure or an increased risk for this...
  5. ncbi request reprint [Measures to prevent or delay type 2 diabetes mellitus]
    I M Jazet
    Leids Universitair Medisch Centrum, afd Algemene Interne Geneeskunde, Leiden
    Ned Tijdschr Geneeskd 152:132-8. 2008
    ..Moreover, the disease course after treatment is discontinued is unknown. --Successful intervention resulting in a sustained effect is expected to have a preventive effect on the long-term complications of type 2 diabetes mellitus...
  6. ncbi request reprint Loss of 50% of excess weight using a very low energy diet improves insulin-stimulated glucose disposal and skeletal muscle insulin signalling in obese insulin-treated type 2 diabetic patients
    I M Jazet
    Department of General Internal Medicine, C4 r 73, Leiden University Medical Centre, P O Box 9600, 2300 RC Leiden, The Netherlands
    Diabetologia 51:309-19. 2008
    ....
  7. ncbi request reprint Sustained beneficial metabolic effects 18 months after a 30-day very low calorie diet in severely obese, insulin-treated patients with type 2 diabetes
    Ingrid M Jazet
    Department of General Internal Medicine, Leiden University Medical Centre, Leiden, The Netherlands
    Diabetes Res Clin Pract 77:70-6. 2007
    ....
  8. ncbi request reprint Adipose tissue as an endocrine organ: impact on insulin resistance
    I M Jazet
    Department of General Internal Medicine C1 r 45, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Neth J Med 61:194-212. 2003
    ..Furthermore, some of these proteins may influence each other via common signalling pathways. A theory is presented to link the interrelationship between these adipocyte secretory products and their effect on insulin resistance...
  9. ncbi request reprint Effect of a 2-day very low-energy diet on skeletal muscle insulin sensitivity in obese type 2 diabetic patients on insulin therapy
    Ingrid M Jazet
    Department of General Internal Medicine C 4 66, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands
    Metabolism 54:1669-78. 2005
    ..Accordingly, no changes in activation of phosphatidylinositol 3'-kinase, triglyceride distribution, FAT/CD36 expression, and GLUT-4 translocation were found in skeletal muscle biopsies...
  10. ncbi request reprint Two days of a very low calorie diet reduces endogenous glucose production in obese type 2 diabetic patients despite the withdrawal of blood glucose-lowering therapies including insulin
    Ingrid M Jazet
    Department of General Internal Medicine, C1 r 45, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands
    Metabolism 54:705-12. 2005
    ..Insulin-stimulated whole body glucose disposal did not improve, nor did insulin suppressibility of EGP and lipolysis...
  11. doi request reprint A 5-day high-fat, high-calorie diet impairs insulin sensitivity in healthy, young South Asian men but not in Caucasian men
    Leontine E H Bakker
    Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands
    Diabetes 63:248-58. 2014
    ..We conclude that HFHC feeding rapidly induces insulin resistance only in SAs. Thus, distinct adaptation to Western food may partly explain their propensity to develop type 2 diabetes. ..
  12. doi request reprint Long-term beneficial effect of a 16-week very low calorie diet on pericardial fat in obese type 2 diabetes mellitus patients
    Marieke Snel
    Department of General Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands
    Obesity (Silver Spring) 20:1572-6. 2012
    ..In conclusion, VLCD-induced weight loss in obese T2DM patients is accompanied by a substantial decrease in pericardial fat volume, which is sustained even after subsequent weight regain...
  13. doi request reprint Effects of adding exercise to a 16-week very low-calorie diet in obese, insulin-dependent type 2 diabetes mellitus patients
    Marieke Snel
    Department of Endocrinology and Metabolism, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    J Clin Endocrinol Metab 97:2512-20. 2012
    ..Reduction of 50% excess body weight, using a very low-calorie diet (VLCD; 450 kcal/d) improves insulin sensitivity in obese type 2 diabetes mellitus patients...
  14. pmc Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases plasma CETP and increases apolipoprotein AI levels without improving the cholesterol efflux properties of HDL
    Yanan Wang
    Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands
    Diabetes Care 34:2576-80. 2011
    ..The aim of the current study was to investigate the effects of prolonged caloric restriction in obese patients with type 2 diabetes mellitus, resulting in a major reduction in hepatic TG content, on plasma CETP and HDL levels...
  15. doi request reprint Immediate and long-term effects of addition of exercise to a 16-week very low calorie diet on low-grade inflammation in obese, insulin-dependent type 2 diabetic patients
    Marieke Snel
    Department of Endocrinology and Metabolism, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Food Chem Toxicol 49:3104-11. 2011
    ..To assess the short- and long-term effects of addition of exercise to a very low calorie diet (VLCD) on low-grade inflammation in obese patients with type 2 diabetes mellitus (T2DM)...
  16. doi request reprint Dietary modulation of plasma angiopoietin-like protein 4 concentrations in healthy volunteers and in patients with type 2 diabetes
    Jacqueline T Jonker
    Departments of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, Netherlands
    Am J Clin Nutr 97:255-60. 2013
    ..Angiopoietin-like protein 4 (ANGPTL4) has been identified as an inhibitor of lipoprotein lipase. Preliminary data suggest that plasma nonesterified fatty acids (NEFAs) raise plasma ANGPTL4 concentrations in humans...
  17. doi request reprint Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1
    Emmani B M Nascimento
    Department of Molecular Cell Biology, Leiden University Medical Centre, Leiden, The Netherlands
    Cell Signal 22:961-7. 2010
    ..We conclude that PRAS40-Ser183 is a component of insulin action, and that efficient phosphorylation of PRAS40-Ser183 by mTORC1 requires the phosphorylation of PRAS40-Thr246 by PKB/Akt...
  18. doi request reprint Sustained cardiac remodeling after a short-term very low calorie diet in type 2 diabetes mellitus patients
    Jacqueline T Jonker
    Department of Endocrinology and Metabolism, Leiden University Medical Center, Leiden, The Netherlands
    Int J Cardiovasc Imaging 30:121-7. 2014
    ..76 (0.65-1.32) %]. Weight reduction by a 16-week VLCD in T2DM patients results in sustained cardiac remodeling and improved diastolic function after 14 months of follow-up, despite weight regain on a regular diet...
  19. doi request reprint Higher insulin and glucagon-like peptide-1 (GLP-1) levels in healthy, young South Asians as compared to Caucasians during an oral glucose tolerance test
    Maria A Sleddering
    Department of General Internal Medicine and Endocrinology and Metabolism, Leiden University Medical Center, Leiden, The Netherlands Electronic address
    Metabolism 63:226-32. 2014
    ....
  20. doi request reprint Quality of life in type 2 diabetes mellitus after a very low calorie diet and exercise
    Marieke Snel
    Department of Endocrinology and Metabolism General Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands
    Eur J Intern Med 23:143-9. 2012
    ..To evaluate whether the addition of exercise to a very low calorie diet (VLCD) has beneficial short- and long-term effects on health-related quality of life (QoL) in obese patients with type 2 diabetes mellitus (T2DM)...
  21. doi request reprint Pathogenesis of type 2 diabetes in South Asians
    Leontine E H Bakker
    Department of General Internal Medicine and Endocrinology Walaeus Library, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Eur J Endocrinol 169:R99-R114. 2013
    ..In this systematic review, we describe several possible mechanisms that may underlie or contribute to the increased IR observed in South Asians. ..
  22. ncbi request reprint Supraclavicular Skin Temperature as a Measure of 18F-FDG Uptake by BAT in Human Subjects
    Mariëtte R Boon
    Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
    PLoS ONE 9:e98822. 2014
    ....
  23. doi request reprint Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases myocardial triglyceride content and improves myocardial function
    Sebastiaan Hammer
    Department of Endocrinology and Metabolism, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 52:1006-12. 2008
    ..This study sought to assess the effects of prolonged caloric restriction in obese patients with type 2 diabetes mellitus (T2DM) on myocardial triglyceride (TG) content and myocardial function...
  24. doi request reprint Short-term topiramate treatment does not improve insulin sensitivity or secretion in obese insulin-resistant women
    Maria A Sleddering
    Department of General Internal Medicine, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Eur J Endocrinol 167:839-45. 2012
    ..Our aim was to evaluate the effect of topiramate treatment for 4 weeks on insulin sensitivity and secretion, independent of weight loss...
  25. doi request reprint Food cues do not modulate the neuroendocrine response to a prolonged fast in healthy men
    Marieke Snel
    Department of General Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands
    Neuroendocrinology 96:285-93. 2012
    ..We hypothesized that the presence of visual and odorous food stimuli during a prolonged fast modifies the neuroendocrine and metabolic response to fasting in humans...
  26. ncbi request reprint Insulin-mediated phosphorylation of the proline-rich Akt substrate PRAS40 is impaired in insulin target tissues of high-fat diet-fed rats
    Emmani B M Nascimento
    Department of Molecular Cell Biology, Section of Signal Transduction and Ageing, Leiden University Medical Center, Postzone S1 P, P O Box 9600, NL 2300 RC Leiden, Netherlands
    Diabetes 55:3221-8. 2006
    ..Phosphorylation of PRAS40 is increased by insulin in human, rat, and mouse insulin target tissues. In rats, this response is reduced under conditions of HFD-induced insulin resistance...
  27. doi request reprint Brown adipose tissue volume in healthy lean south Asian adults compared with white Caucasians: a prospective, case-controlled observational study
    Leontine E H Bakker
    Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, Netherlands
    Lancet Diabetes Endocrinol 2:210-7. 2014
    ....
  28. ncbi request reprint [Brown adipose tissue: the body's own weapon against obesity?]
    Mariëtte R Boon
    Leids Universitair Medisch Centrum, afd Algemene Interne Geneeskunde, Leiden, The Netherlands
    Ned Tijdschr Geneeskd 157:A5502. 2013
    ..g. exposure to cold, the use of so-called uncoupling agents or the administration of the hormone irisin. The activation of BAT could potentially be used to induce weight loss...