Yvonne M C Hendriks

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi Heterozygous mutations in PMS2 cause hereditary nonpolyposis colorectal carcinoma (Lynch syndrome)
    Yvonne M C Hendriks
    Center for Human and Clinical Genetics, Leiden University Medical Center, The Netherlands
    Gastroenterology 130:312-22. 2006
  2. ncbi The natural history of a combined defect in MSH6 and MUTYH in a HNPCC family
    Marjo van Puijenbroek
    Department of Pathology, Leiden University Medical Center, Building L1Q, P O Box 9600, 2300 RC Leiden, The Netherlands
    Fam Cancer 6:43-51. 2007
  3. ncbi Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance
    Yvonne M C Hendriks
    Center of Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
    Gastroenterology 127:17-25. 2004
  4. ncbi Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians
    Yvonne M C Hendriks
    Center of Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
    CA Cancer J Clin 56:213-25. 2006
  5. doi GPSM2 and Chudley-McCullough syndrome: a Dutch founder variant brought to North America
    Rowida Almomani
    Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
    Am J Med Genet A 161:973-6. 2013
  6. ncbi Decrease in mortality in Lynch syndrome families because of surveillance
    Andrea E de Jong
    The Netherlands Foundation for the Detection of Hereditary Tumors, Leiden University Medical Center, Leiden, The Netherlands
    Gastroenterology 130:665-71. 2006

Collaborators

Detail Information

Publications6

  1. ncbi Heterozygous mutations in PMS2 cause hereditary nonpolyposis colorectal carcinoma (Lynch syndrome)
    Yvonne M C Hendriks
    Center for Human and Clinical Genetics, Leiden University Medical Center, The Netherlands
    Gastroenterology 130:312-22. 2006
    ..To date, only 7 different heterozygous truncating PMS2 mutations have been reported in HNPCC-suspected families. Our aim was to further assess the role of PMS2 in HNPCC...
  2. ncbi The natural history of a combined defect in MSH6 and MUTYH in a HNPCC family
    Marjo van Puijenbroek
    Department of Pathology, Leiden University Medical Center, Building L1Q, P O Box 9600, 2300 RC Leiden, The Netherlands
    Fam Cancer 6:43-51. 2007
    ..In conclusion, these data would support the notion that abrogation of both MSH6 DNA mismatch repair and base repair might be mutually exclusive in humans...
  3. ncbi Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance
    Yvonne M C Hendriks
    Center of Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
    Gastroenterology 127:17-25. 2004
    ..Hereditary nonpolyposis colorectal carcinoma (HNPCC) is caused by a mutated mismatch repair (MMR) gene. The aim of our study was to determine the cumulative risk of developing cancer in a large series of MSH6 mutation carriers...
  4. ncbi Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians
    Yvonne M C Hendriks
    Center of Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
    CA Cancer J Clin 56:213-25. 2006
    ..The diagnostic scheme presented here allows efficient and effective analysis of colorectal carcinoma cases with (suspected) Lynch syndrome, making optimal use of currently available technology...
  5. doi GPSM2 and Chudley-McCullough syndrome: a Dutch founder variant brought to North America
    Rowida Almomani
    Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
    Am J Med Genet A 161:973-6. 2013
    ..Since the c.1473delG variant was found in Mennonite settlers, it likely originated in Europe. To support DNA diagnostics, we established an LOVD database for GPSM2 containing all variants thus far described...
  6. ncbi Decrease in mortality in Lynch syndrome families because of surveillance
    Andrea E de Jong
    The Netherlands Foundation for the Detection of Hereditary Tumors, Leiden University Medical Center, Leiden, The Netherlands
    Gastroenterology 130:665-71. 2006
    ....