Research Topics
| Frans M HelmerhorstSummaryAffiliation: Leiden University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Intrauterine insemination versus timed intercourse for cervical hostility in subfertile couplesFrans M Helmerhorst
Department of Gynaecology, Division of Reproductive Medicine, Leiden University Medical Center, Leiden, The Netherlands
Obstet Gynecol Surv 61:402-14; quiz 423. 2006..Grimes, KF Schulz, Obstetrical and Gynecologic Survey, 57; Supplement 3: S35, September 2002; and D. Grimes, KF Schulz, Obstetrical and Gynecologic Survey, Supplement 2, S53-S69, September 2005.-RBJ...- The Cochrane Fertility Regulation Group: synthesizing the best evidence about family planningFrans M Helmerhorst
Fertility Regulation Group of the Cochrane Collaboration, Division of Reproductive Medicine, Department of Gynaecology, Leiden University Medical Center, Leiden, The Netherlands
Contraception 74:280-6. 2006..Systematic reviews of evidence, with an emphasis on randomized controlled trials when available, will continue to improve fertility regulation in the years ahead... 
Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studiesFrans M Helmerhorst
Department of Obstetrics, Gynaecology and Reproductive Medicine, Leiden University Medical Center, NL 2300 Leiden, Netherlands
BMJ 328:261. 2004..To compare the perinatal outcome of singleton and twin pregnancies between natural and assisted conceptions...
Perinatal outcome, health, growth, and medical care utilization of 5- to 8-year-old intracytoplasmic sperm injection singletonsMarjolein Knoester
Department of Pediatrics, Neonatal Center, Leiden University Medical Center, Leiden, The Netherlands
Fertil Steril 89:1133-46. 2008..To evaluate short- and long-term health in intracytoplasmic sperm injection (ICSI) singletons...- Cognitive development of singletons born after intracytoplasmic sperm injection compared with in vitro fertilization and natural conceptionMarjolein Knoester
Department of Pediatrics, Neonatal Center, Leiden University Medical Center, Leiden, The Netherlands
Fertil Steril 90:289-96. 2008..To investigate cognitive development of singletons conceived by intracytoplasmic sperm injection (ICSI) at 5-8 years of age... - The effect of the levonorgestrel-releasing intrauterine system on the resistance to activated protein C (APC)Huib A A M van Vliet
Department of Gynaecology and Reproductive Medicine, Leiden University Medical Center, Leiden, The Netherlands
Thromb Haemost 101:691-5. 2009..48; 95% CI -0.85 to -2.11). In this study we observed that the levonorgestrel-intrauterine system decreases the resistance to APC which indicates that the levonorgestrel-intrauterine system does not have a prothrombotic effect... - The risk of deep venous thrombosis associated with injectable depot-medroxyprogesterone acetate contraceptives or a levonorgestrel intrauterine deviceAstrid van Hylckama Vlieg
Department of Clinical Epidemiology, Leiden University Medical Center, C7 P, PO Box 9600, NL 2300 RC Leiden, The Netherlands
Arterioscler Thromb Vasc Biol 30:2297-300. 2010.... - Pericellular-acting proteases in human first trimester deciduaMargreet Plaisier
Division of Reproductive Medicine, Department of Gynaecology, Leiden University Medical Centre, PO Box 9600, 2300 RC, Leiden, The Netherlands
Mol Hum Reprod 14:41-51. 2008..These data are consistent with a differential regulation of pericellular proteases in decidua by pregnancy-induced hormones, immune cells and EVT... - Matched follow-up study of 5-8 year old ICSI-singletons: comparison of their neuromotor development to IVF and naturally conceived singletonsMarjolein Knoester
Department of Paediatrics, Neonatal Center, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Hum Reprod 22:1638-46. 2007..Intracytoplasmic sperm injection (ICSI) is an invasive technique of artificial reproduction. We investigated the effect of ICSI on neuromotor development in 5-8 year old singletons... - Screening for unrecognized coeliac disease in subfertile couplesCaroline E Hogen Esch
Department of Paediatric Gastroenterology, Leiden University Medical Center, Leiden, Netherlands
Scand J Gastroenterol 46:1423-8. 2011..We aimed to determine the prevalence of unrecognized CD in subfertile male-female couples visiting a fertility clinic compared with the general population... - Quadriphasic versus monophasic oral contraceptives for contraceptionHuib Aam Van Vliet
Department of Gynaecology, Division of Reproductive Medicine, Leiden University Medical Center, PO Box 9600, Albinusdreef 2, Leiden, Netherlands, NL 2300 RC
Cochrane Database Syst Rev 11:CD009038. 2011.... - Conventional in vitro fertilization versus intracytoplasmic sperm injection in patients with borderline semen: a randomized study using sibling oocytesLucette van der Westerlaken
Department of Reproductive Medicine, Leiden University Medical Center, Leiden, The Netherlands
Fertil Steril 85:395-400. 2006..To determine whether patients with borderline semen should be treated with conventional IVF or intracytoplasmic sperm injection (ICSI)... - Triphasic versus monophasic oral contraceptives for contraceptionHuib Aam Van Vliet
Department of Gynaecology, Division of Reproductive Medicine, Leiden University Medical Center, PO Box 9600, Leiden, Netherlands, 2300 RC
Cochrane Database Syst Rev 11:CD003553. 2011..Whether triphasic OCs have higher accidental pregnancy rates than monophasic pills is unknown. Nor is it known if triphasic pills give better cycle control and fewer side effects than the monophasic pills... - An analysis of systematic reviews indicated low incorpororation of results from clinical trial quality assessmentAnton J M de Craen
Department of General Internal Medicine, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
J Clin Epidemiol 58:311-3. 2005..We investigated the frequency of quality assessment of randomized controlled trials within systematic reviews and the incorporation of the quality assessment in the analysis... - Vaginal misoprostol prior to insertion of an intrauterine device: an RCTKirsten Dijkhuizen
Department of Gynaecology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Hum Reprod 26:323-9. 2011..Here, we investigate whether vaginal misoprostol administered prior to intrauterine device (IUD) insertion reduces the number of failed insertions, insertion-related complications and pain during insertion... - Sensitivity to activated protein C during the menstrual cycle in women with and without factor VLeidenHuib A A M van Vliet
Department of Gynaecology, Division of Reproductive Medicine, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
Thromb Res 121:757-61. 2008..The aim of the study was to evaluate whether varying levels of estradiol and progesterone during the menstrual cycle are associated with differences in sensitivity to APC... - Thrombophilias and gynaecologyKitty W M Bloemenkamp
Department of Obstetrics, Gynaecology and Reproductive Medicine, Leiden University Medical Center, P O Box 9600, RC 2300, Leiden, The Netherlands
Best Pract Res Clin Obstet Gynaecol 17:509-28. 2003..Emerging studies show that in vitro fertilization treatment and ovulation induction are also risk factors for venous thrombosis; the role of coagulation defects in this association is not yet clear... - Retention of estradiol negative feedback relationship to LH predicts ovulation in response to caloric restriction and weight loss in obese patients with polycystic ovary syndromeEveline W C M van Dam
Department of General Internal Medicine, Leiden University Medical Center, C1-R39, 2300 RC Leiden, The Netherlands
Am J Physiol Endocrinol Metab 286:E615-20. 2004..We infer that evidence of retention of estradiol-dependent negative feedback on LH secretion may forecast follicle maturation and ovulation in obese patients with PCOS under dietary restriction... - Different degrees of vascularization and their relationship to the expression of vascular endothelial growth factor, placental growth factor, angiopoietins, and their receptors in first-trimester decidual tissuesMargreet Plaisier
Department of Biomedical Research, TNO Quality of Life, Leiden, The Netherlands
Fertil Steril 88:176-87. 2007..Comparison of these tissues provides information about the regulation of vascularization by pregnancy-induced hormones and/or the extravillous trophoblast (EVT)... - Increase in daily LH secretion in response to short-term calorie restriction in obese women with PCOSEveline W C M van Dam
Department of Endocrinology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
Am J Physiol Endocrinol Metab 282:E865-72. 2002..Enhanced LH secretion in the presence of normal metabolic and hormonal adaptations to calorie restriction points to anomalous feedback control of pituitary LH release in PCOS... - Injection of embryo culture supernatant prior to blastocyst transfer--cofactor?Kitty Kapiteijn
Fertil Steril 89:1027-8; author reply 1028. 2008 - How many eggs?Marc J N C Keirse
BMJ 329:302-3. 2004 - Combination estrogen-progestin contraceptives and body weight: systematic review of randomized controlled trialsMaria F Gallo
Family Health International, Research Triangle Park, North Carolina, USA
Obstet Gynecol 103:359-73. 2004..CONCLUSION: Available evidence is insufficient to determine the effect of combination contraceptives on weight, but no large effect is evident... - Biphasic versus triphasic oral contraceptives for contraceptionHubertus A A M van Vliet
Family Health International, Research Triangle Park, NC 27709, USA
Contraception 65:321-4. 2002..This suggests that the choice of progestin may be more important that the phasic regimen in determining bleeding patterns... - Biphasic versus monophasic oral contraceptives for contraception: a Cochrane reviewHubertus A A M van Vliet
Family Health International, P.O.Box 13950, Research Triangle Park, North Carolina 27709, USA
Hum Reprod 17:870-3. 2002..Since no clear rationale exists for biphasic pills and since extensive evidence is available for monophasic pills, the latter are preferred... - The value of Chlamydia trachomatis-specific IgG antibody testing and hysterosalpingography for predicting tubal pathology and occurrence of pregnancyDenise A M Perquin
Department of Obstetrics and Gynecology, Medical Center Haaglanden, The Hague, The Netherlands
Fertil Steril 88:224-6. 2007..The diagnostic accuracy and prognostic value of both C. trachomatis-specific IgG antibody testing and HSG are comparable but show poor performance...