Genomes and Genes


D A Hamstra


Affiliation: Leiden University
Country: The Netherlands


  1. Hamstra D, de Kloet E, van Hemert A, de Rijk R, Van der Does A. Mineralocorticoid receptor haplotype, oral contraceptives and emotional information processing. Neuroscience. 2015;286:412-22 pubmed publisher
    ..No hormonal measures were taken. Most naturally cycling participants were assessed in the luteal phase of their menstrual cycle. Carriers of MR haplotype 2 may be less sensitive to depressogenic side-effects of OCs. ..
  2. Hamstra D, de Kloet E, Tollenaar M, Verkuil B, Manaï M, Putman P, et al. Mineralocorticoid receptor haplotype moderates the effects of oral contraceptives and menstrual cycle on emotional information processing. J Psychopharmacol. 2016;30:1054-61 pubmed publisher
    ..MR-haplotype 2 carriers showed more risky decision-making. As this may reflect optimistic expectations, this finding may support previous observations in female carriers of MR-haplotype 2 in a naturalistic cohort study. ..
  3. Hamstra D, de Kloet E, Quataert I, Jansen M, Van der Does W. Mineralocorticoid receptor haplotype, estradiol, progesterone and emotional information processing. Psychoneuroendocrinology. 2017;76:162-173 pubmed publisher
    ..Performance in the attentional blink task may be influenced by OC-use. The MR-genotype moderates the influence of E2 and P4 on emotional information processing. This moderating effect may depend on the novelty of the situation. ..
  4. Hamstra D, de Kloet E, De Rover M, Van der Does W. Oral contraceptives positively affect mood in healthy PMS-free women: A longitudinal study. J Psychosom Res. 2017;103:119-126 pubmed publisher
    ..Limitations were loss of cases due to irregularities in the menstrual cycle length and possible confounding by the 'survivor effect', since almost all OC-users took OC for more than a year. ..