Research Topics
| Jairo GooskensSummaryAffiliation: Leiden University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Streptococcal toxic shock syndrome by an iMLS resistant M type 77 Streptococcus pyogenes in the NetherlandsJ Gooskens
Department of Medical Microbiology, Centre of Infectious Diseases, University Medical Centre of Leiden, Bilthoven, The Netherlands
Scand J Infect Dis 37:85-9. 2005..Since only 12% carried the ermA [TR] resistance gene, it is very likely that the gene has been acquired by horizontal transmission rather than from spread of a resistant circulating clone...
Quantitative detection of herpes simplex virus DNA in the lower respiratory tractJ Gooskens
Department of Medical Microbiology, Center of Infectious Diseases, Leiden, University Medical Center, P O Box 9600, 2300 RC, Leiden, The Netherlands
J Med Virol 79:597-604. 2007..We conclude that quantitative detection of HSV DNA in bronchoalveolar lavage fluid is a potential diagnostic tool for detection of relevant viral infection of the lower respiratory tract...
Severe influenza resembling hemorrhagic shock and encephalopathy syndromeJ Gooskens
Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands
J Clin Virol 39:136-40. 2007..The failure to detect viral replication in non-pulmonary organs including the brain would support the pathogenesis of this syndrome is based on proinflammatory cytokine responses...
Rapid molecular detection of influenza outbreaks in nursing homesJ Gooskens
Department of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
J Clin Virol 41:7-12. 2008..Nursing home influenza outbreaks occur in spite of established vaccination programs, and require rapid and sensitive laboratory confirmation for timely intervention...
Morbidity and mortality associated with nosocomial transmission of oseltamivir-resistant influenza A(H1N1) virusJairo Gooskens
Department of Medical Microbiology, E4 65, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands
JAMA 301:1042-6. 2009..Viruses carrying this mutation are widely presumed to exhibit attenuated pathogenicity, compromised transmission, and reduced lethality...
Prolonged influenza virus infection during lymphocytopenia and frequent detection of drug-resistant virusesJairo Gooskens
Department of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands
J Infect Dis 199:1435-41. 2009..Clinical improvement in influenza lower respiratory tract infection is observed during oseltamivir treatment, but complete viral clearance is dependent on lymphocyte reconstitution, irrespective of receipt of antiviral medication...
Clinical challenges and images in GI. Syphilitic sigmoiditis complicated by membranous nephropathyJairo Gooskens
Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands
Gastroenterology 135:363, 716. 2008
Evaluation of an internally controlled real-time PCR targeting the ospA gene for detection of Borrelia burgdorferi sensu lato DNA in cerebrospinal fluidJ Gooskens
Department of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands
Clin Microbiol Infect 12:894-900. 2006..burgdorferi sensu lato species tested. The PCR had a sensitivity of 50% in patients with neuroborreliosis. The main diagnostic role of the assay could be to confirm neuroborreliosis in patients for whom the diagnosis is doubtful...
