A C Gittenberger-de Groot

Summary

Affiliation: Leiden University
Country: The Netherlands

Publications

  1. ncbi Epicardium-derived cells contribute a novel population to the myocardial wall and the atrioventricular cushions
    A C Gittenberger-de Groot
    Department of Anatomy and Embryology, Leiden University Medical Center, Netherlands
    Circ Res 82:1043-52. 1998
  2. ncbi Epicardial outgrowth inhibition leads to compensatory mesothelial outflow tract collar and abnormal cardiac septation and coronary formation
    A C Gittenberger-de Groot
    Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
    Circ Res 87:969-71. 2000
  3. ncbi Smoothelin expression during chicken embryogenesis: detection of an embryonic isoform
    M C DeRuiter
    Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
    Dev Dyn 221:460-3. 2001
  4. doi Expression of Id2 in the second heart field and cardiac defects in Id2 knock-out mice
    M R M Jongbloed
    Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
    Dev Dyn 240:2561-77. 2011
  5. doi Cell tracking using iron oxide fails to distinguish dead from living transplanted cells in the infarcted heart
    E M Winter
    Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
    Magn Reson Med 63:817-21. 2010
  6. ncbi Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus
    M Bergwerff
    Department of Anatomy and Embryology, Leiden University Medical Centre, P O Box 9602, 2300 RC Leiden, The Netherlands
    Virchows Arch 436:12-9. 2000
  7. ncbi Expression patterns of the paired-related homeobox genes MHox/Prx1 and S8/Prx2 suggest roles in development of the heart and the forebrain
    B Leussink
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht
    Mech Dev 52:51-64. 1995
  8. ncbi TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes
    L P Sanford
    Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati, OH 45267, USA
    Development 124:2659-70. 1997
  9. ncbi Differential expression of alpha-6 and other subunits of laminin binding integrins during development of the murine heart
    B P Hierck
    Department of Anatomy and Embryology, Leiden University, The Netherlands
    Dev Dyn 206:100-11. 1996
  10. ncbi Congenital polyvalvular disease: a review
    U Bartram
    Department of Pediatric Cardiology, University Children's Hospital Kiel, Germany
    Pediatr Cardiol 22:93-101. 2001

Collaborators

Detail Information

Publications13

  1. ncbi Epicardium-derived cells contribute a novel population to the myocardial wall and the atrioventricular cushions
    A C Gittenberger-de Groot
    Department of Anatomy and Embryology, Leiden University Medical Center, Netherlands
    Circ Res 82:1043-52. 1998
    ..Furthermore, a regulatory role is postulated in the process of endocardial-mesenchymal transformation. The ultimate fate of EPDCs seems to be a cardiac fibroblast cell line involved in the formation of the fibrous heart skeleton...
  2. ncbi Epicardial outgrowth inhibition leads to compensatory mesothelial outflow tract collar and abnormal cardiac septation and coronary formation
    A C Gittenberger-de Groot
    Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
    Circ Res 87:969-71. 2000
    ..Heterospecific epicardial transplant is able to partially rescue the myocardial development, as well as septation and coronary formation...
  3. ncbi Smoothelin expression during chicken embryogenesis: detection of an embryonic isoform
    M C DeRuiter
    Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
    Dev Dyn 221:460-3. 2001
    ..Expression of the smoothelin isoforms seems to be strictly controlled with respect to cell type and developmental stage and may be related to the mode of contraction of the different cells...
  4. doi Expression of Id2 in the second heart field and cardiac defects in Id2 knock-out mice
    M R M Jongbloed
    Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
    Dev Dyn 240:2561-77. 2011
    ..Our results indicate a role for Id2 in the second heart field contribution at both the arterial and the venous poles of the heart...
  5. doi Cell tracking using iron oxide fails to distinguish dead from living transplanted cells in the infarcted heart
    E M Winter
    Department of Anatomy and Embryology, Leiden University Medical Center, Leiden, The Netherlands
    Magn Reson Med 63:817-21. 2010
    ..Iron labeling is inadequate for determining the fate of transplanted cells in the immunodeficient host, since dead cells produce an MRI signal indistinguishable from incorporated living cells...
  6. ncbi Loss of function of the Prx1 and Prx2 homeobox genes alters architecture of the great elastic arteries and ductus arteriosus
    M Bergwerff
    Department of Anatomy and Embryology, Leiden University Medical Centre, P O Box 9602, 2300 RC Leiden, The Netherlands
    Virchows Arch 436:12-9. 2000
    ..The current findings suggest that other genes may compensate for the loss of Prx in the heart, but, in contrast, our data support a role for Prx in the development of vascular and perivascular matrix...
  7. ncbi Expression patterns of the paired-related homeobox genes MHox/Prx1 and S8/Prx2 suggest roles in development of the heart and the forebrain
    B Leussink
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht
    Mech Dev 52:51-64. 1995
    ..Prx2 is never expressed in the brain, whereas Prx1 is expressed, from at least day 9.5 onwards, in a unique distinct domain in the ventral part of the hypothalamus, as well as in a broader region of the telencephalon...
  8. ncbi TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes
    L P Sanford
    Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati, OH 45267, USA
    Development 124:2659-70. 1997
    ..There is no phenotypic overlap with TGFbeta1- and TGFbeta3-null mice indicating numerous non-compensated functions between the TGFbeta isoforms...
  9. ncbi Differential expression of alpha-6 and other subunits of laminin binding integrins during development of the murine heart
    B P Hierck
    Department of Anatomy and Embryology, Leiden University, The Netherlands
    Dev Dyn 206:100-11. 1996
    ..This study suggests a distinct role for alpha-6-beta-1 in the heart and provides insight concerning probably important roles of integrins and their extracellular matrix ligands during embryonic development...
  10. ncbi Congenital polyvalvular disease: a review
    U Bartram
    Department of Pediatric Cardiology, University Children's Hospital Kiel, Germany
    Pediatr Cardiol 22:93-101. 2001
    ..Two cases are used for exemplification. The macroscopic and histologic features of the valves as well as associated cardiac lesions and clinical syndromes are described, followed by a discussion of morphogenesis of this disease...
  11. ncbi Frizzled 2 is transiently expressed in neural crest-containing areas during development of the heart and great arteries in the mouse
    M E van Gijn
    Department of Pharmacology, Universiteit Maastricht, The Netherlands
    Anat Embryol (Berl) 203:185-92. 2001
    ..This expression is downregulated upon neural crest cell differentiation. The frizzled 2 expression supports a role for the Wnt-frizzled pathway in neural crest-related disorders...
  12. ncbi Magnetic resonance microscopy at 17.6-Tesla on chicken embryos in vitro
    B Hogers
    Department of Anatomy, Leiden University Medical Center, Leiden, The Netherlands
    J Magn Reson Imaging 14:83-6. 2001
    ..Thus, ultra high field is beneficial for MRM and opens new areas for functional imaging research, in particular when SNR, resolution, and contrast are limited by acquisition time...
  13. ncbi Expression of the beta 4 integrin subunit in the mouse heart during embryonic development: retinoic acid advances beta 4 expression
    B P Hierck
    Department of Anatomy and Embryology, University of Leiden, The Netherlands
    Dev Dyn 207:89-103. 1996
    ..Several hypotheses on the mechanism of beta 4 up-regulation and a possible role for alpha 6 beta 4 in the development of heart malformations after the administration of retinoic acid are discussed...