Erik J Giltay

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. pmc No effects of n-3 fatty acid supplementation on serum total testosterone levels in older men: the Alpha Omega Trial
    E J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Int J Androl 35:680-7. 2012
  2. pmc Effects of n-3 fatty acids on depressive symptoms and dispositional optimism after myocardial infarction
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Netherlands
    Am J Clin Nutr 94:1442-50. 2011
  3. doi request reprint Salivary testosterone: associations with depression, anxiety disorders, and antidepressant use in a large cohort study
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Psychosom Res 72:205-13. 2012
  4. doi request reprint Predicting outcomes of mood, anxiety and somatoform disorders: the Leiden routine outcome monitoring study
    Martijn S van Noorden
    Leiden University Medical Center, Department of Psychiatry, PO Box 7500, 2300 RC Leiden, The Netherlands
    J Affect Disord 142:122-31. 2012
  5. doi request reprint Antidepressant use and salivary cortisol in depressive and anxiety disorders
    Leonie Manthey
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Eur Neuropsychopharmacol 21:691-9. 2011
  6. doi request reprint Physical activity after myocardial infarction: is it related to mental health?
    Nathaly Rius-Ottenheim
    Leiden University Medical Centre, Department of Psychiatry, Leiden, The Netherlands
    Eur J Prev Cardiol 20:399-408. 2013
  7. doi request reprint Low respiratory function increases the risk of depressive symptoms in later life in men
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, 2300 RC Leiden, Netherlands
    Psychosom Med 72:53-60. 2010
  8. doi request reprint Dimensions of depression and anxiety and the hypothalamo-pituitary-adrenal axis
    Klaas J Wardenaar
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Biol Psychiatry 69:366-73. 2011
  9. doi request reprint Symptom dimensions of depression and anxiety and the metabolic syndrome
    Floriana S Luppino
    Department of Psychiatry, Leiden University Medical Center, Albinusdreef 2, P O BOX 2300 RC Leiden, Netherlands
    Psychosom Med 73:257-64. 2011
  10. doi request reprint Prevalence, demographic and clinical characteristics of body dysmorphic disorder among psychiatric outpatients with mood, anxiety or somatoform disorders
    Job van der Meer
    Department of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands
    Nord J Psychiatry 66:232-8. 2012

Collaborators

Detail Information

Publications65

  1. pmc No effects of n-3 fatty acid supplementation on serum total testosterone levels in older men: the Alpha Omega Trial
    E J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Int J Androl 35:680-7. 2012
    ..0 nmol/L). We conclude that n-3 fatty acids supplementation did not affect serum total testosterone in men who had had a MI...
  2. pmc Effects of n-3 fatty acids on depressive symptoms and dispositional optimism after myocardial infarction
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Netherlands
    Am J Clin Nutr 94:1442-50. 2011
    ..In patients who have experienced a myocardial infarction (MI), n-3 (omega-3) PUFA status is low, whereas the risk of depression is increased...
  3. doi request reprint Salivary testosterone: associations with depression, anxiety disorders, and antidepressant use in a large cohort study
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Psychosom Res 72:205-13. 2012
    ..The use of selective serotonin reuptake inhibitors (SSRIs) and other antidepressants is associated with sexual side effects, warranting testing for interactions with testosterone...
  4. doi request reprint Predicting outcomes of mood, anxiety and somatoform disorders: the Leiden routine outcome monitoring study
    Martijn S van Noorden
    Leiden University Medical Center, Department of Psychiatry, PO Box 7500, 2300 RC Leiden, The Netherlands
    J Affect Disord 142:122-31. 2012
    ..The purpose of this study was to predict outcomes in outpatients with MAS disorders using routine outcome monitoring (ROM) data...
  5. doi request reprint Antidepressant use and salivary cortisol in depressive and anxiety disorders
    Leonie Manthey
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Eur Neuropsychopharmacol 21:691-9. 2011
    ..03). These findings suggest that antidepressant subtypes are associated with distinct alterations of the HPA axis. TCA users, who showed a flattened CAR, displayed the strongest alterations of salivary cortisol...
  6. doi request reprint Physical activity after myocardial infarction: is it related to mental health?
    Nathaly Rius-Ottenheim
    Leiden University Medical Centre, Department of Psychiatry, Leiden, The Netherlands
    Eur J Prev Cardiol 20:399-408. 2013
    ..We aimed to analyse the cross-sectional and prospective associations between physical activity and mental wellbeing in patients with a history of myocardial infarction...
  7. doi request reprint Low respiratory function increases the risk of depressive symptoms in later life in men
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, 2300 RC Leiden, Netherlands
    Psychosom Med 72:53-60. 2010
    ..Chronic lung diseases are associated with a high prevalence of depression, but the association of poor respiratory function with depressive symptoms has not been established in prospective population-based cohort studies...
  8. doi request reprint Dimensions of depression and anxiety and the hypothalamo-pituitary-adrenal axis
    Klaas J Wardenaar
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Biol Psychiatry 69:366-73. 2011
    ..Specific symptom-dimensions could be used as a more homogenous phenotype in HPA-axis research...
  9. doi request reprint Symptom dimensions of depression and anxiety and the metabolic syndrome
    Floriana S Luppino
    Department of Psychiatry, Leiden University Medical Center, Albinusdreef 2, P O BOX 2300 RC Leiden, Netherlands
    Psychosom Med 73:257-64. 2011
    ..The categorical nature of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition might partly explain the inconsistent findings...
  10. doi request reprint Prevalence, demographic and clinical characteristics of body dysmorphic disorder among psychiatric outpatients with mood, anxiety or somatoform disorders
    Job van der Meer
    Department of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands
    Nord J Psychiatry 66:232-8. 2012
    ..To describe the prevalence, demographic and clinical characteristics of body dysmorphic disorder (BDD) compared with other psychiatric outpatients with a mood, anxiety or somatoform disorder...
  11. doi request reprint Basal cortisol levels in relation to dimensions and DSM-IV categories of depression and anxiety
    Gerthe Veen
    Department of Psychiatry, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Psychiatry Res 185:121-8. 2011
    ..The present study shows that linear and nonlinear associations with salivary cortisol are detected when using phenotypic dimensions and may be complementary to phenotypic DSM-IV categories when doing neuroendocrine research...
  12. pmc Parental longevity correlates with offspring's optimism in two cohorts of community-dwelling older subjects
    Nathaly Rius-Ottenheim
    Department of Psychiatry, Leiden University Medical Centre, The Netherlands
    Age (Dordr) 34:461-8. 2012
    ..30 (SE = 0.08, p < 0.001). In conclusion, parental longevity was positively associated with optimism in adult offspring, suggesting a partial linked heritability of longevity and optimism...
  13. pmc Apolipoprotein E genotype modifies the association between midlife lung function and cognitive function in old age
    Erik J Giltay
    Leiden University Medical Center, Department of Psychiatry, NL 2300 RC Leiden, The Netherlands
    Dement Geriatr Cogn Disord 28:433-41. 2009
    ....
  14. doi request reprint Determinants of initiated and continued benzodiazepine use in the Netherlands study of depression and anxiety
    Leonie Manthey
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Clin Psychopharmacol 31:774-9. 2011
    ..We aimed to identify the most important predictors of initiated and continued BZD use. Therefore, we analyzed the most consistently identified determinants from previous research plus some new determinants...
  15. pmc Correlates of (inappropriate) benzodiazepine use: the Netherlands Study of Depression and Anxiety (NESDA)
    Leonie Manthey
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Br J Clin Pharmacol 71:263-72. 2011
    ..The relative importance of sociodemographic, psychological and physical determinants has never been investigated in a comprehensive, multivariate model...
  16. doi request reprint Longitudinal relationship of depressive and anxiety symptoms with dyslipidemia and abdominal obesity
    Arianne K B van Reedt Dortland
    Department of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands
    Psychosom Med 75:83-9. 2013
    ..Previous research indicates that patients with severe symptoms of depression or anxiety are prone toward the development of dyslipidemia and abdominal obesity. We sought to study these associations longitudinally...
  17. doi request reprint Effects of testosterone supplementation on depressive symptoms and sexual dysfunction in hypogonadal men with the metabolic syndrome
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Sex Med 7:2572-82. 2010
    ..Low testosterone levels in men are associated with the metabolic syndrome (MetS) as well as with depressive symptoms, low vitality, and sexual dysfunction...
  18. pmc C-reactive protein haplotypes and dispositional optimism in obese and nonobese elderly subjects
    Nathaly Rius-Ottenheim
    Department of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands
    Inflamm Res 61:43-51. 2012
    ..Using a Mendelian randomization design, this study explores whether CRP haplotypes that determine CRP plasma levels are also associated with dispositional optimism...
  19. pmc Telomere length and mental well-being in elderly men from the Netherlands and Greece
    Nathaly Rius-Ottenheim
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Behav Genet 42:278-86. 2012
    ..Thus, our results provide no support for a relationship between leukocyte telomere length and mental well-being in elderly community-dwelling men...
  20. doi request reprint Prevalence and correlates of lifetime deliberate self-harm and suicidal ideation in naturalistic outpatients: the Leiden Routine Outcome Monitoring study
    Suzanne de Klerk
    Department of Psychiatry, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    J Affect Disord 133:257-64. 2011
    ..Aims of the study are to determine the prevalence and correlates of lifetime DSHI in a naturalistic sample of psychiatric outpatients with mood, anxiety or somatoform (MAS) disorders...
  21. doi request reprint Long-term benzodiazepine use and salivary cortisol: the Netherlands Study of Depression and Anxiety (NESDA)
    Leonie Manthey
    Department of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands
    J Clin Psychopharmacol 30:160-8. 2010
    ..During short-term treatment, BZD use was found to suppress cortisol levels. However, little research has been done on the effects of long-term BZD administration on the hypothalamic-pituitary-adrenal (HPA) axis...
  22. doi request reprint Evening salivary alpha-amylase, major depressive disorder, and antidepressant use in the Netherlands Study of Depression and Anxiety (NESDA)
    Gerthe Veen
    Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
    Psychiatry Res 208:41-6. 2013
    ..The present study shows that higher evening sAA levels in depressed patients, indicative of an increased sympathetic activity, may be induced by TCAs...
  23. pmc Reference values for generic instruments used in routine outcome monitoring: the Leiden Routine Outcome Monitoring Study
    Yvonne W M Schulte-van Maaren
    Department of Psychiatry, Leiden University Medical Center, Leiden, RC 2300, The Netherlands
    BMC Psychiatry 12:203. 2012
    ..We aimed to generate reference values usually encountered in 'healthy' and 'psychiatrically ill' populations to facilitate correct interpretation of ROM results...
  24. doi request reprint Reference values for major depression questionnaires: the Leiden Routine Outcome Monitoring Study
    Yvonne W M Schulte-van Maaren
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Affect Disord 149:342-9. 2013
    ..We aimed to generate reference values for both "healthy" and "clinically depressed" populations...
  25. ncbi request reprint Musicians seeking psychiatric help: a preliminary study of psychiatric characteristics
    Esther Van Fenema
    Dept of Psychiatry B1 P, Leiden University Medical Center, Leiden, The Netherlands
    Med Probl Perform Art 28:9-18. 2013
    ....
  26. doi request reprint Determinants of salivary evening α-amylase in a large sample free of psychopathology
    Gerthe Veen
    Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
    Int J Psychophysiol 84:33-8. 2012
    ..In this paper, we report about correlates of evening sAA in saliva...
  27. doi request reprint Predicting outcome of depression using the depressive symptom profile: the Leiden Routine Outcome Monitoring Study
    Martijn S van Noorden
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Depress Anxiety 29:523-30. 2012
    ..To investigate the predictive value of items for individual depressive symptoms measured with the self-rated Beck Depression Inventory-Revised (BDI-II) self-report scale on outcome in a large naturalistic cohort of depressive outpatients...
  28. doi request reprint Personality traits and childhood trauma as correlates of metabolic risk factors: the Netherlands Study of Depression and Anxiety (NESDA)
    Arianne K B van Reedt Dortland
    Department of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands
    Prog Neuropsychopharmacol Biol Psychiatry 36:85-91. 2012
    ..Moreover, despite their interrelatedness, personality and childhood trauma were not yet studied simultaneously. Therefore, we aimed to explore whether personality and childhood trauma are correlates of metabolic risk factors...
  29. doi request reprint The structure and dimensionality of the Inventory of Depressive Symptomatology Self Report (IDS-SR) in patients with depressive disorders and healthy controls
    Klaas J Wardenaar
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Affect Disord 125:146-54. 2010
    ..However previous factoranalytical studies have found mixed results. Therefore, the present study tested which factor structure underlies the IDS-SR and, in addition, if the factors can be used as unidimensional subscales...
  30. doi request reprint Salivary cortisol, serum lipids, and adiposity in patients with depressive and anxiety disorders
    Gerthe Veen
    Department of Psychiatry, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Metabolism 58:821-7. 2009
    ..These data lend support to the hypothesis that the relationship between affective disorders and cardiovascular disease is partly mediated by HPA-axis perturbations...
  31. doi request reprint Incidence, course, and predictors of apathy in Huntington's disease: a two-year prospective study
    Nanda Reedeker
    Department of Psychiatry, Leiden University Medical Center, The Netherlands
    J Neuropsychiatry Clin Neurosci 23:434-41. 2011
    ..Twenty subjects had persistent apathy, with a low baseline Symbol Digits Modalities Test as the only predictor. These results showed that apathy in HD is most closely linked to global and executive cognitive performance...
  32. doi request reprint Associations between serum lipids and major depressive disorder: results from the Netherlands Study of Depression and Anxiety (NESDA)
    Arianne K B van Reedt Dortland
    Leiden University Medical Centre, Department of Psychiatry, PO Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Psychiatry 71:729-36. 2010
    ..However, previous studies did not always take into consideration potentially mediating factors or heterogeneity of symptoms, which may clarify contradicting findings...
  33. doi request reprint Trauma exposure in relation to basal salivary cortisol and the hormone response to the dexamethasone/CRH test in male railway employees without lifetime psychopathology
    Ellen R Klaassens
    Department of Psychiatry, Leiden University Medical Center LUMC, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Psychoneuroendocrinology 35:878-86. 2010
    ..We aimed to explore whether trauma exposure is associated with alterations in HPA-axis functioning in the absence of lifetime psychiatric morbidity...
  34. doi request reprint Effects of childhood trauma on HPA-axis reactivity in women free of lifetime psychopathology
    Ellen R Klaassens
    Department of Psychiatry, Leiden University Medical Center LUMC, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Prog Neuropsychopharmacol Biol Psychiatry 33:889-94. 2009
    ..Although basal cortisol patterns were similar in the two groups, exposure to childhood trauma seemed to be related to a blunted HPA-axis reactivity in women who were free of current or lifetime psychopathology...
  35. doi request reprint Dispositional optimism and loneliness in older men
    Nathaly Rius-Ottenheim
    Leiden University Medical Centre, Department of Psychiatry, Leiden, The Netherlands
    Int J Geriatr Psychiatry 27:151-9. 2012
    ..We aimed to determine whether dispositional optimism is prospectively associated with less feelings of loneliness, independently of potential confounders inherent to the aging process...
  36. doi request reprint C-reactive protein polymorphisms are associated with the cortisol awakening response in basal conditions in human subjects
    Gerthe Veen
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Stress 14:128-35. 2011
    ..Hence, genetic variants in the CRP gene that are associated with lifetime plasma CRP levels were also associated with salivary cortisol levels after awakening, in basal, non-inflammatory conditions...
  37. doi request reprint Reference values for mental health assessment instruments: objectives and methods of the Leiden Routine Outcome Monitoring Study
    Yvonne W M Schulte-van Maaren
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Eval Clin Pract 19:342-50. 2013
    ..This article describes the extensive process of recruitment, as well as baseline characteristics of patient versus non-patient groups...
  38. doi request reprint Dimensions of the inventory of depressive symptomatology as predictors of the course of depressive and anxiety disorders
    Klaas J Wardenaar
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Psychiatr Res 46:1655-61. 2012
    ..In conclusion, the widely used IDS-SR can be used to measure two dimensions that contribute prognostic value on top of other, previously known prognostic factors...
  39. doi request reprint Vitality predicts level of guideline-concordant care in routine treatment of mood, anxiety and somatoform disorders
    Esther M van Fenema
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Eval Clin Pract 18:441-8. 2012
    ..To examine the clinical and psychosocial correlates of adherence to treatment guidelines among outpatients with common mental disorders in a routine clinical setting...
  40. doi request reprint Self-rated health and physician-rated health as independent predictors of mortality in elderly men
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, P O Box 9600, 2300 RC, Leiden, The Netherlands
    Age Ageing 41:165-71. 2012
    ..When assessing health status, physicians may focus on objective symptoms and diagnoses, whereas individuals may focus more on subjective symptoms, functional limitations and quality of life...
  41. doi request reprint Correlates of benzodiazepine dependence in the Netherlands Study of Depression and Anxiety
    Leonie Manthey
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Addiction 107:2173-82. 2012
    ..Benzodiazepines (BZDs) are effective in the short term against anxiety and insomnia. However, some BZD users develop BZD dependence after a relatively short period of time. Therefore, we aimed to identify the risk factors of BZD dependence...
  42. doi request reprint Irritability in Huntington's disease
    Nanda Reedeker
    Department of Psychiatry, Leiden University Medical Centre, The Netherlands
    Psychiatry Res 200:813-8. 2012
    ..Although it is unclear whether benzodiazepine use causes irritability, or irritability leads to the prescription of benzodiazepines, clinical evaluation with respect to the use of benzodiazepines in HD warrants attention...
  43. doi request reprint Cardiovascular risk profile and subsequent disability and mental well-being: the Zutphen Elderly Study
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Am J Geriatr Psychiatry 16:874-82. 2008
    ..Objectives: It is insufficiently known whether "classic" cardiovascular risk factors are associated with subsequent functional disability and mental well-being in elderly men...
  44. doi request reprint Risk of depressive symptoms in the oldest old subjects with chronic obstructive pulmonary disease: the Leiden 85-plus study
    Nathaly Rius Ottenheim
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Am J Geriatr Psychiatry 18:388-94. 2010
    ..The authors aimed to determine whether oldest old persons with COPD are at increased risk of developing depressive symptoms...
  45. doi request reprint Gender differences in clinical characteristics in a naturalistic sample of depressive outpatients: the Leiden Routine Outcome Monitoring Study
    Martijn S van Noorden
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Affect Disord 125:116-23. 2010
    ..We therefore determined gender differences in comorbidity, symptom patterns and subjective health status in these outpatients in a mental healthcare setting...
  46. doi request reprint Hypothalamic-pituitary-adrenal axis functioning in Huntington's disease mutation carriers compared with mutation-negative first-degree controls
    Erik van Duijn
    Department of Psychiatry, Leiden University Medical Center, The Netherlands
    Brain Res Bull 83:232-7. 2010
    ..No differences were found for the AUC, evening and post-DST cortisol concentrations. Our study indicates a mild disturbance in morning cortisol secretion in HD mutation carriers that precedes the onset of motor symptoms...
  47. doi request reprint The impact of stress systems and lifestyle on dyslipidemia and obesity in anxiety and depression
    Arianne K B van Reedt Dortland
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Psychoneuroendocrinology 38:209-18. 2013
    ..We aimed to elucidate whether biological stress systems or lifestyle factors underlie these associations. If so, they may be useful targets for CVD prevention and intervention...
  48. doi request reprint Symptom dimensions as predictors of the two-year course of depressive and anxiety disorders
    Klaas J Wardenaar
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Affect Disord 136:1198-203. 2012
    ..Therefore, it was investigated whether symptom-dimensions could be used as more specific course-predictors, on top of already known predictors, such as diagnosis and overall severity...
  49. doi request reprint Adulthood trauma and HPA-axis functioning in healthy subjects and PTSD patients: a meta-analysis
    Ellen R Klaassens
    Department of Psychiatry, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Psychoneuroendocrinology 37:317-31. 2012
    ..Yet, trauma exposure rather than PTSD may be responsible for HPA-axis dysregulation. In two meta-analyses, we assessed the association of adulthood trauma exposure and HPA-axis functioning in healthy subjects with and without PTSD...
  50. doi request reprint Development and validation of a 30-item short adaptation of the Mood and Anxiety Symptoms Questionnaire (MASQ)
    Klaas J Wardenaar
    Department of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands
    Psychiatry Res 179:101-6. 2010
    ..In conclusion, the MASQ-D30 is a valid instrument to assess dimensional aspects of depression and anxiety and can easily be implemented in psychopathology studies...
  51. doi request reprint Reference values for anxiety questionnaires: the Leiden Routine Outcome Monitoring Study
    Yvonne W M Schulte-van Maaren
    Department of Psychiatry, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    J Affect Disord 150:1008-18. 2013
    ..We aimed to generate reference values for both 'healthy' and 'clinically anxious' populations for these anxiety questionnaires...
  52. doi request reprint MRI characteristics predicting seizure threshold in patients undergoing electroconvulsive therapy: a prospective study
    Jeroen A van Waarde
    Rijnstate Hospital, Department of Psychiatry, P O Box 9555, 6800 TA Arnhem, The Netherlands
    Brain Stimul 6:607-14. 2013
    ..In electroconvulsive therapy (ECT), the electrical current must pass the scalp, skull, cerebrospinal fluid (CSF) and brain tissues, to sufficiently exceed the seizure threshold (ST)...
  53. pmc Clinical predictors of seizure threshold in electroconvulsive therapy: a prospective study
    Jeroen A van Waarde
    Department of Psychiatry, Rijnstate Hospital, P O Box 9555, 6800 TA, Arnhem, The Netherlands
    Eur Arch Psychiatry Clin Neurosci 263:167-75. 2013
    ..Increasing age and BL electrode placement predicted higher (I)ST, which should be taken into account when selecting ECT dosage. Previous ECT course(s) may avoid an increase in ST during the course of ECT...
  54. doi request reprint The efficacy of n-3 fatty acids DHA and EPA (fish oil) for perinatal depression
    Linda A W Jans
    Institute of Psychology, Leiden University, Leiden, The Netherlands
    Br J Nutr 104:1577-85. 2010
    ..Future research should focus on women who are clinically depressed (or at risk). The quality of research in this area needs to improve...
  55. doi request reprint Respiratory function and other biological risk factors for completed suicide: 40 years of follow-up of European cohorts of the Seven Countries Study
    Erik J Giltay
    Leiden University Medical Center, Department of Psychiatry, Leiden, The Netherlands
    J Affect Disord 120:249-53. 2010
    ..Prospective cohort studies on biological risk factors of completed suicide are scarce. We aimed to test which biological risk factors independently identify subjects at increased risk of suicidal death...
  56. doi request reprint Trauma exposure and hypothalamic-pituitary- adrenal axis functioning in mentally healthy Dutch peacekeeping veterans, 10-25 years after deployment
    Ellen R Klaassens
    Department of Psychiatry, Leiden University Medical Center LUMC, Leiden, The Netherlands
    J Trauma Stress 23:124-31. 2010
    ..The authors concluded that this study does not support the idea that HPA-axis functioning is durably altered by trauma exposure during adulthood in men...
  57. doi request reprint Course of Irritability, Depression and Apathy in Huntington's Disease in Relation to Motor Symptoms during a Two-Year Follow-Up Period
    Erik van Duijn
    Department of Psychiatry, Leiden University Medical Centre, Leiden, The Netherlands
    Neurodegener Dis 13:9-16. 2014
    ..02). Conclusion: An increase in motor symptoms in the at baseline premotor symptomatic mutation carriers is related to an increase in irritability, which may be an early and sensitive marker for disease progression. ..
  58. ncbi request reprint Lifestyle and dietary correlates of dispositional optimism in men: The Zutphen Elderly Study
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Psychosom Res 63:483-90. 2007
    ..We therefore studied whether dispositional optimism was associated with healthy lifestyle and dietary habits...
  59. doi request reprint Serum cholesterol, apolipoprotein E genotype and depressive symptoms in elderly European men: the FINE study
    Erik J Giltay
    Leiden University Medical Center, Department of Psychiatry, Leiden, The Netherlands
    J Affect Disord 115:471-7. 2009
    ..Using a Mendelian randomization design, the potential association between apolipoprotein E (APOE) genotype (affecting lifetime cholesterol levels) and depressive symptoms was studied...
  60. doi request reprint Suicidal ideation in a European Huntington's disease population
    Anna A M Hubers
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    J Affect Disord 151:248-58. 2013
    ..This study investigates correlates and predictors of suicidal ideation in HD...
  61. doi request reprint Coeliac disease, diet adherence and depressive symptoms
    Nathalie J M van Hees
    Institute of Psychology, Leiden University, Leiden, The Netherlands
    J Psychosom Res 74:155-60. 2013
    ..We aimed to investigate whether long-term adherence to a gluten-free diet is related to depressive symptoms in coeliac disease (CD) patients...
  62. doi request reprint The influence of psychiatric comorbidity on the dexamethasone/CRH test in major depression
    Gerthe Veen
    Department of Psychiatry, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    Eur Neuropsychopharmacol 19:409-15. 2009
    ..The present study investigated whether comorbidity of anxiety or somatoform disorders might be an explaining factor for this finding...
  63. doi request reprint Effects of sex steroids on the neurotransmitter-specific aromatic amino acids phenylalanine, tyrosine, and tryptophan in transsexual subjects
    Erik J Giltay
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Neuroendocrinology 88:103-10. 2008
    ..The aim of this study was to assess whether sex steroids affect plasma levels of these aromatic amino acids...
  64. doi request reprint Hypokinesia in Huntington's disease co-occurs with cognitive and global dysfunctioning
    Nanda Reedeker
    Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
    Mov Disord 25:1612-8. 2010
    ..In conclusion, the presence of moderate to severe hypokinesia in HD patients co-occurs with executive cognitive dysfunction and adversely affects global functioning...
  65. doi request reprint The effect of aripiprazole and quinagolide, a dopamine agonist, in a patient with symptomatic pituitary prolactinoma and chronic psychosis
    Rosalie Broekhof
    Department of Psychiatry, Leiden University Medical Center, P O Box 9600, 2300RC, Leiden, The Netherlands
    Gen Hosp Psychiatry 34:209.e1-3. 2012
    ..Aripiprazole, as a partial D(2) receptor agonist, may be the drug of choice in patients suffering from both psychosis and prolactinoma...