L Fregonese

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi Expression of the anaphylatoxin receptors C3aR and C5aR is increased in fatal asthma
    Laura Fregonese
    Department of Pulmonology, Leiden University Medical Centre, Albinusdreef 2, 2233 ZA Leiden, The Netherlands
    J Allergy Clin Immunol 115:1148-54. 2005
  2. ncbi Ventilation inhomogeneity in alpha1-antitrypsin-deficient emphysema
    L Fregonese
    Lung Function Laboratory, Dept of Pulmonology C3 P, Leiden University Medical Centre, P O Box 9600, 2300 RC Leiden, The Netherlands
    Eur Respir J 28:323-9. 2006
  3. doi Alpha-1 antitrypsin Null mutations and severity of emphysema
    Laura Fregonese
    Department of Pulmonology, Leiden University Medical Centre, Leiden, The Netherlands
    Respir Med 102:876-84. 2008
  4. pmc Hereditary alpha-1-antitrypsin deficiency and its clinical consequences
    Laura Fregonese
    Alpha1 International Registry, c o Department of Pulmology, Leiden University Medical Center, Leiden, The Netherlands
    Orphanet J Rare Dis 3:16. 2008
  5. ncbi Steroid-naive adolescents with mild intermittent allergic asthma have airway hyperresponsiveness and elevated exhaled nitric oxide levels
    Daniela Spallarossa
    Pulmonary Division, G Gaslini Institute, Genoa, Italy
    J Asthma 40:301-10. 2003
  6. doi Proteomic analysis of exhaled breath condensate from single patients with pulmonary emphysema associated to alpha1-antitrypsin deficiency
    Marco Fumagalli
    Dipartimento di Biochimica A Castellani, Universita di Pavia, Italy
    J Proteomics 71:211-21. 2008
  7. ncbi Clinical, physiologic, and roentgenographic changes after pneumonectomy in a boy with Macleod/Swyer-James syndrome and bronchiectasis
    Laura Fregonese
    Pulmonology Division, G Gaslini Institute, Genoa, Italy
    Pediatr Pulmonol 34:412-6. 2002
  8. ncbi Correlations between exhaled nitric oxide levels, blood eosinophilia, and airway obstruction reversibility in childhood asthma are detectable only in atopic individuals
    Michela Silvestri
    Pulmonary Division, G Gaslini Institute, Genoa, Italy
    Pediatr Pulmonol 35:358-63. 2003

Collaborators

Detail Information

Publications8

  1. ncbi Expression of the anaphylatoxin receptors C3aR and C5aR is increased in fatal asthma
    Laura Fregonese
    Department of Pulmonology, Leiden University Medical Centre, Albinusdreef 2, 2233 ZA Leiden, The Netherlands
    J Allergy Clin Immunol 115:1148-54. 2005
    ..Recent studies suggest the involvement of the anaphylatoxins C3a and C5a, generated during complement activation, and their receptors C3aR and C5aR in the pathogenesis of asthma...
  2. ncbi Ventilation inhomogeneity in alpha1-antitrypsin-deficient emphysema
    L Fregonese
    Lung Function Laboratory, Dept of Pulmonology C3 P, Leiden University Medical Centre, P O Box 9600, 2300 RC Leiden, The Netherlands
    Eur Respir J 28:323-9. 2006
    ..Determination of the sensitivity of the single-breath nitrogen wash-out test slope in detecting disease progression may give complementary information to spirometry...
  3. doi Alpha-1 antitrypsin Null mutations and severity of emphysema
    Laura Fregonese
    Department of Pulmonology, Leiden University Medical Centre, Leiden, The Netherlands
    Respir Med 102:876-84. 2008
    ..Mutations causing total absence of serum AAT (Null mutations) were suggested to be associated with very early onset emphysema but their clinical phenotype is poorly known...
  4. pmc Hereditary alpha-1-antitrypsin deficiency and its clinical consequences
    Laura Fregonese
    Alpha1 International Registry, c o Department of Pulmology, Leiden University Medical Center, Leiden, The Netherlands
    Orphanet J Rare Dis 3:16. 2008
    ..The end-stage liver and lung disease can be treated by organ transplantation. In AATD patients with cirrhosis, prognosis is generally grave...
  5. ncbi Steroid-naive adolescents with mild intermittent allergic asthma have airway hyperresponsiveness and elevated exhaled nitric oxide levels
    Daniela Spallarossa
    Pulmonary Division, G Gaslini Institute, Genoa, Italy
    J Asthma 40:301-10. 2003
    ....
  6. doi Proteomic analysis of exhaled breath condensate from single patients with pulmonary emphysema associated to alpha1-antitrypsin deficiency
    Marco Fumagalli
    Dipartimento di Biochimica A Castellani, Universita di Pavia, Italy
    J Proteomics 71:211-21. 2008
    ..These sensitive techniques allowed to identify a number of cytokines and cytokeratins. Their level was found to be higher in patients than in controls...
  7. ncbi Clinical, physiologic, and roentgenographic changes after pneumonectomy in a boy with Macleod/Swyer-James syndrome and bronchiectasis
    Laura Fregonese
    Pulmonology Division, G Gaslini Institute, Genoa, Italy
    Pediatr Pulmonol 34:412-6. 2002
    ..Despite the severe impairment of pulmonary function, the patient underwent resection of the right lung with progressive improvement of clinical and physiologic parameters...
  8. ncbi Correlations between exhaled nitric oxide levels, blood eosinophilia, and airway obstruction reversibility in childhood asthma are detectable only in atopic individuals
    Michela Silvestri
    Pulmonary Division, G Gaslini Institute, Genoa, Italy
    Pediatr Pulmonol 35:358-63. 2003
    ..04). Within the atopic group, no differences were found between mono- and polysensitized individuals in all parameters evaluated. Thus only in atopic children did parameters of inflammation correlate with airway obstruction reversibility...