Research Topics
Species | Dinanda J de JagerSummaryAffiliation: Leiden University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Is the decline of renal function different before and after the start of dialysis?Dinanda J de Jager
Department of Clinical Epidemiology, Leiden University MedicalCentre, Leiden, The Netherlands
Nephrol Dial Transplant 28:698-705. 2013..This study explores the time course of the glomerular filtration rate (GFR) between 1 year before and 1 year after the start of haemodialysis (HD) and peritoneal dialysis (PD)...
Cardiovascular and noncardiovascular mortality among patients starting dialysisDinanda J de Jager
Department of Clinical Epidemiology, Leiden University Medical Center, C7 104, PO Box 9600, 2300 RC Leiden, The Netherlands
JAMA 302:1782-9. 2009..Cardiovascular mortality is considered the main cause of death in patients receiving dialysis and is 10 to 20 times higher in such patients than in the general population...
Association between time of referral and survival in the first year of dialysis in diabetics and the elderlyDinanda J de Jager
Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands
Nephrol Dial Transplant 26:652-8. 2011..The objective of the study was to estimate the association between time of referral and survival during dialysis in diabetics and patients aged≥70 years...
Changes in parathyroid hormone, body mass index and the association with mortality in dialysis patientsChristiane Drechsler
Department of Clinical Epidemiology, LUMC, Leiden, The Netherlands
Nephrol Dial Transplant 26:1340-6. 2011..Obesity is associated with secondary hyperparathyroidism in the general population. It is unknown whether body mass index (BMI) affects parathyroid hormone (PTH) level and its association with mortality in dialysis patients...
Association between a self-rated health question and mortality in young and old dialysis patients: a cohort studyMelissa S Y Thong
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Am J Kidney Dis 52:111-7. 2008..We assessed whether an SRH item predicts mortality in a large sample of incident dialysis patients beyond sociodemographic, disease, and clinical measures and possible age interaction...
Disordered mineral metabolism is not a risk factor for loss of residual renal function in dialysis patientsMarlies Noordzij
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DD Amsterdam, The Netherlands
Nephrol Dial Transplant 24:1580-7. 2009..We examined associations between parameters of mineral metabolism and loss of residual renal function (RRF) in dialysis patients...
Subjective global assessment of nutritional status is strongly associated with mortality in chronic dialysis patientsRenée de Mutsert
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Am J Clin Nutr 89:787-93. 2009..The subjective global assessment of nutritional status (SGA) is used to assess the nutritional status of chronic dialysis patients, but longitudinal data in relation to mortality risk are lacking...
Association of body mass index with decline in residual kidney function after initiation of dialysisChristiane Drechsler
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Am J Kidney Dis 53:1014-23. 2009..Our aim was to study the effects of body mass index (BMI) on decline in kidney function and risk to develop anuria after initiation of dialysis therapy...
Association of blood pressure with the start of renal replacement therapy in elderly compared with young patients receiving predialysis careMoniek C M de Goeij
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Am J Hypertens 25:1175-81. 2012..Therefore, we investigated the association of systolic (SBP) and diastolic blood pressure (DBP) with the start of renal replacement therapy (RRT), in elderly (≥65 years) compared with young (<65 years) predialysis patients...
Patients' representations of their end-stage renal disease: relation with mortalitySandra van Dijk
Department of Medical Psychology, Leiden University Medical Center, Leiden, The Netherlands
Nephrol Dial Transplant 24:3183-5. 2009..g. via adherence to treatment). Following these assumptions, we explored whether illness perceptions of ESRD-patients are related to mortality rates...
Association of blood pressure with decline in renal function and time until the start of renal replacement therapy in pre-dialysis patients: a cohort studyMoniek C M de Goeij
Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, Leiden, The Netherlands
BMC Nephrol 12:38. 2011....
Proteinuria as a risk marker for the progression of chronic kidney disease in patients on predialysis care and the role of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker treatmentMoniek C M de Goeij
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Nephron Clin Pract 121:c73-82. 2012..Therefore, we investigated the association of urinary protein excretion (UPE) and ACEi/ARB treatment with renal function decline (RFD) and/or the start of renal replacement therapy (RRT) in patients on predialysis care...
Progression of aortic calcification is associated with disorders of mineral metabolism and mortality in chronic dialysis patientsMarlies Noordzij
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Nephrol Dial Transplant 26:1662-9. 2011..In addition, we assessed the impact of aortic calcification on mortality...
Predictors of poor outcome in chronic dialysis patients: The Netherlands Cooperative Study on the Adequacy of Dialysis. The NECOSAD Study GroupM P Merkus
Department of Clinical Epidemiology, Academic Medical Center, Amsterdam, The Netherlands
Am J Kidney Dis 35:69-79. 2000..Strategies aimed at preserving residual renal function, controlling blood pressure, monitoring QL, and consequently giving psychosocial support may reduce the risk for poor outcome...
Reporting of interactionDinanda J de Jager
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Nephron Clin Pract 119:c158-61. 2011....
Excellent agreement between C-reactive protein measurement methods in end-stage renal disease patients--no additional power for mortality prediction with high-sensitivity CRPDiana C Grootendorst
Leiden University Medical Center, Department of Clinical Epidemiology C9 29, P O Box 9600 2300 RC Leiden, The Netherlands
Nephrol Dial Transplant 22:3277-84. 2007..The aim of this study was to determine agreement between imCRP and hsCRP in end-stage renal disease (ESRD) patients, and to examine whether the association between CRP and mortality is comparable when using imCRP or hsCRP...
Mendelian randomization: use of genetics to enable causal inference in observational studiesMarion Verduijn
Department of Clinical Epidemiology, Leiden University Medical Center, P O Box 9600 2300 RC Leiden, The Netherlands
Nephrol Dial Transplant 25:1394-8. 2010..This educational article describes the approach of Mendelian randomization, its underlying rationale and its necessary assumptions...
Survival analysis: time-dependent effects and time-varying risk factorsFriedo W Dekker
Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands
Kidney Int 74:994-7. 2008..It will be shown that using time-dependent risk factors usually implies focusing on short-term effects only...
Observational studies are complementary to randomized controlled trialsDiana C Grootendorst
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Nephron Clin Pract 114:c173-7. 2010..Examples from the nephrology literature are used for illustration...
The analysis of competing events like cause-specific mortality--beware of the Kaplan-Meier methodMarion Verduijn
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Nephrol Dial Transplant 26:56-61. 2011....
Screening: why, when, and howDiana C Grootendorst
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands
Kidney Int 76:694-9. 2009....
Racial minority groups on dialysis in Europe: a literature reviewT O van den Beukel
Department of Clinical Epidemiology, Leiden University Medical Center, University of Leiden, Leiden, The Netherlands
Clin Nephrol 74:S78-84. 2010....
Interaction on an additive scaleRenée de Mutsert
Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands
Nephron Clin Pract 119:c154-7. 2011....
The effect of joint exposures: examining the presence of interactionRenée de Mutsert
Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands
Kidney Int 75:677-81. 2009....
Cohort studies: prospective versus retrospectiveAnne M Euser
Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands
Nephron Clin Pract 113:c214-7. 2009..If one is aware of this, cohort studies can form a potent study design in nephrology producing, in general, highly generalizable results...
