Diederik Pc De Rooy

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. doi request reprint Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study
    Diederik P C de Rooy
    From the Department of Rheumatology, and the Department of Medical Statistics, Leiden University Medical Center, Leiden, the Netherlands the Section of Rheumatology at the Institution of Clinical Science, Lund University, Skane University Hospital, Lund, Sweden, for the BARFOT study group the Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands Center of Experimental Rheumatology, University Hospital Zurich, Schlieren, Switzerland the Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands D P de Rooy, LLM, MD, PhD, Department of Rheumatology, Leiden University Medical Center R Tsonaka, PhD, Department of Medical Statistics, Leiden University Medical Center M L Andersson, BMS, PhD K Forslind, Associate Professor, Senior Consultant, Section of Rheumatology at the Institution of Clinical Science, Lund University, Skane University Hospital, for the BARFOT study group A Zhernakova, MD, PhD, Department of Rheumatology, Leiden University Medical Center, and Department of Genetics, University Medical Center Groningen and University of Groningen M Frank Bertoncelj
    J Rheumatol 42:1383-91. 2015
  2. doi request reprint Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis
    Diederik P C de Rooy
    Department of Rheumatology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands
    Ann Rheum Dis 72:769-75. 2013
  3. doi request reprint Predicting arthritis outcomes--what can be learned from the Leiden Early Arthritis Clinic?
    Diederik P C de Rooy
    Department of Rheumatology, Leiden University Medical Center, C1 46, PO Box 9600, 2300 RC, Leiden, The Netherlands
    Rheumatology (Oxford) 50:93-100. 2011
  4. doi request reprint Loss of metacarpal bone density predicts RA development in recent-onset arthritis
    Diederik P C de Rooy
    Department of Rheumatology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Rheumatology (Oxford) 51:1037-41. 2012
  5. pmc Can anti-cyclic citrullinated peptide antibody-negative RA be subdivided into clinical subphenotypes?
    Diederik P C de Rooy
    Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
    Arthritis Res Ther 13:R180. 2011

Detail Information

Publications5

  1. doi request reprint Genetic Factors for the Severity of ACPA-negative Rheumatoid Arthritis in 2 Cohorts of Early Disease: A Genome-wide Study
    Diederik P C de Rooy
    From the Department of Rheumatology, and the Department of Medical Statistics, Leiden University Medical Center, Leiden, the Netherlands the Section of Rheumatology at the Institution of Clinical Science, Lund University, Skane University Hospital, Lund, Sweden, for the BARFOT study group the Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands Center of Experimental Rheumatology, University Hospital Zurich, Schlieren, Switzerland the Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands D P de Rooy, LLM, MD, PhD, Department of Rheumatology, Leiden University Medical Center R Tsonaka, PhD, Department of Medical Statistics, Leiden University Medical Center M L Andersson, BMS, PhD K Forslind, Associate Professor, Senior Consultant, Section of Rheumatology at the Institution of Clinical Science, Lund University, Skane University Hospital, for the BARFOT study group A Zhernakova, MD, PhD, Department of Rheumatology, Leiden University Medical Center, and Department of Genetics, University Medical Center Groningen and University of Groningen M Frank Bertoncelj
    J Rheumatol 42:1383-91. 2015
    ..At the individual level, however, considerable differences in the severity of joint destruction occur. We performed a study on genetic factors underlying the differences in joint destruction in ACPA-negative patients...
  2. doi request reprint Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis
    Diederik P C de Rooy
    Department of Rheumatology, Leiden University Medical Center, PO Box 9600, Leiden 2300 RC, The Netherlands
    Ann Rheum Dis 72:769-75. 2013
    ..Dickkopf-1 (Dkk-1) and sclerostin (Sost) are negative regulators and lipoprotein receptor-related protein-5 (LRP-5) and Kremen-1 are transmembrane receptors involved in this pathway...
  3. doi request reprint Predicting arthritis outcomes--what can be learned from the Leiden Early Arthritis Clinic?
    Diederik P C de Rooy
    Department of Rheumatology, Leiden University Medical Center, C1 46, PO Box 9600, 2300 RC, Leiden, The Netherlands
    Rheumatology (Oxford) 50:93-100. 2011
    ..In early undifferentiated arthritis (UA), prediction of the development of RA is crucial, and in case of RA predicting the severity of the disease course may guide individualized treatment decisions...
  4. doi request reprint Loss of metacarpal bone density predicts RA development in recent-onset arthritis
    Diederik P C de Rooy
    Department of Rheumatology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Rheumatology (Oxford) 51:1037-41. 2012
    ..We determined the ability of radiographic BMD loss to predict RA development and arthritis persistency in patients with early undifferentiated arthritis (UA)...
  5. pmc Can anti-cyclic citrullinated peptide antibody-negative RA be subdivided into clinical subphenotypes?
    Diederik P C de Rooy
    Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
    Arthritis Res Ther 13:R180. 2011
    ..We aimed to evaluate the validity of this notion and explored whether clinical subphenotypes can be discerned within anti-CCP-negative RA...