C L Creutzberg

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi The morbidity of treatment for patients with Stage I endometrial cancer: results from a randomized trial
    C L Creutzberg
    Department of Radiation Oncology, University Hospital Rotterdam Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 51:1246-55. 2001
  2. ncbi The role of radiotherapy in endometrial cancer: current evidence and trends
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, The Netherlands
    Curr Oncol Rep 13:472-8. 2011
  3. ncbi Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, The Netherlands
    Int J Radiat Oncol Biol Phys 81:e631-8. 2011
  4. ncbi Adjuvant chemotherapy for endometrial cancer: unproven
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Gynecol Cancer 20:1105-8. 2010
  5. ncbi Adjuvant chemotherapy for endometrial cancer: unproven
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, RC Leiden, The Netherlands
    Int J Gynecol Cancer 20:S60-3. 2010
  6. ncbi Survival after relapse in patients with endometrial cancer: results from a randomized trial
    Carien L Creutzberg
    Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    Gynecol Oncol 89:201-9. 2003
  7. ncbi Outcome of high-risk stage IC, grade 3, compared with stage I endometrial carcinoma patients: the Postoperative Radiation Therapy in Endometrial Carcinoma Trial
    Carien L Creutzberg
    Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    J Clin Oncol 22:1234-41. 2004
  8. ncbi Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma
    C L Creutzberg
    Department of Radiation Oncology, University Hospital Rotterdam Daniel den Hoed Cancer Center, The Netherlands
    Lancet 355:1404-11. 2000
  9. ncbi Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial
    R A Nout
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, Netherlands
    Lancet 375:816-23. 2010
  10. ncbi Postoperative radiation therapy improves prognosis in patients with adverse risk factors in localized, early-stage cervical cancer: a retrospective comparative study
    Q D Pieterse
    Department of Gynaecology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Int J Gynecol Cancer 16:1112-8. 2006

Detail Information

Publications24

  1. ncbi The morbidity of treatment for patients with Stage I endometrial cancer: results from a randomized trial
    C L Creutzberg
    Department of Radiation Oncology, University Hospital Rotterdam Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 51:1246-55. 2001
    ..To compare the treatment complications for patients with Stage I endometrial cancer treated with surgery and pelvic radiotherapy (RT) or surgery alone in a multicenter randomized trial...
  2. ncbi The role of radiotherapy in endometrial cancer: current evidence and trends
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, The Netherlands
    Curr Oncol Rep 13:472-8. 2011
    ..Current ongoing trials are exploring the role of combined RT and chemotherapy, compared to chemotherapy or RT alone...
  3. ncbi Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, The Netherlands
    Int J Radiat Oncol Biol Phys 81:e631-8. 2011
    ....
  4. ncbi Adjuvant chemotherapy for endometrial cancer: unproven
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Gynecol Cancer 20:1105-8. 2010
    ..Toxicity and quality of life data are lacking. The role of adjuvant chemotherapy for endometrial carcinoma remains unproven. High-risk EC remains the challenge for further research...
  5. ncbi Adjuvant chemotherapy for endometrial cancer: unproven
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, RC Leiden, The Netherlands
    Int J Gynecol Cancer 20:S60-3. 2010
    ..Toxicity and quality-of-life data are lacking. The role of adjuvant chemotherapy for endometrial carcinoma remains unproven. High-risk EC remains the challenge for further research...
  6. ncbi Survival after relapse in patients with endometrial cancer: results from a randomized trial
    Carien L Creutzberg
    Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    Gynecol Oncol 89:201-9. 2003
    ..The aim of this study was to determine the rates of local control and survival after relapse in patients with stage I endometrial cancer treated in the multicenter randomized PORTEC trial...
  7. ncbi Outcome of high-risk stage IC, grade 3, compared with stage I endometrial carcinoma patients: the Postoperative Radiation Therapy in Endometrial Carcinoma Trial
    Carien L Creutzberg
    Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    J Clin Oncol 22:1234-41. 2004
    ..Stage IC, grade 3 patients were not eligible for the randomized Postoperative Radiation Therapy in Endometrial Carcinoma (PORTEC) trial, but were registered and received postoperative radiotherapy...
  8. ncbi Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma
    C L Creutzberg
    Department of Radiation Oncology, University Hospital Rotterdam Daniel den Hoed Cancer Center, The Netherlands
    Lancet 355:1404-11. 2000
    ..We did a multicentre prospective randomised trial to find whether postoperative pelvic radiotherapy improves locoregional control and survival for patients with stage-1 endometrial carcinoma...
  9. ncbi Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial
    R A Nout
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, Netherlands
    Lancet 375:816-23. 2010
    ..This study established whether vaginal brachytherapy (VBT) is as effective as pelvic external beam radiotherapy (EBRT) in prevention of vaginal recurrence, with fewer adverse effects and improved quality of life...
  10. ncbi Postoperative radiation therapy improves prognosis in patients with adverse risk factors in localized, early-stage cervical cancer: a retrospective comparative study
    Q D Pieterse
    Department of Gynaecology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Int J Gynecol Cancer 16:1112-8. 2006
    ..HR patients benefit from adjuvant RT. The LUMC modification of the GOG system seems to be simpler and has a slightly higher threshold for the indication for RT but without a difference in outcome...
  11. ncbi Combined E-cadherin, alpha-catenin, and beta-catenin expression is a favorable prognostic factor in endometrial carcinoma
    A N Scholten
    Department of Clinical Oncology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Int J Gynecol Cancer 16:1379-85. 2006
    ..02). Negative E-cadherin expression was found to be associated with histologic grade 3 and with NEEC. Combined positive E-cadherin, alpha-catenin, and beta-catenin expression was a significant prognostic factor...
  12. ncbi [Is there an indication for additional local irradiation in conserving treatment of breast cancer patients aged 60 and over?]
    E M Noordijk
    Leids Universitair Medisch Centrum, afd Klinische Oncologie, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 146:395-8. 2002
    ..0%). Therefore it is questionable whether an additional dose of 16 Gy (reducing the recurrence rate to 2.5%) is still justified as a standard treatment in this age group...
  13. ncbi Long-term outcome and quality of life of patients with endometrial carcinoma treated with or without pelvic radiotherapy in the post operative radiation therapy in endometrial carcinoma 1 (PORTEC-1) trial
    Remi A Nout
    Department of Clinical Oncology, Leiden University Medical Center, PO PO Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Oncol 29:1692-700. 2011
    ....
  14. ncbi Long-term outcome in endometrial carcinoma favors a two- instead of a three-tiered grading system
    Astrid N Scholten
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Radiat Oncol Biol Phys 52:1067-74. 2002
    ..A retrospective analysis of long-term outcome and predictive factors in endometrial carcinoma was conducted, focusing on the prognostic value of tumor grade...
  15. ncbi Efficacy of a hypofractionated schedule in electron beam radiotherapy for epithelial skin cancer: Analysis of 434 cases
    Marjan van Hezewijk
    Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Radiother Oncol 95:245-9. 2010
    ..Efficacy of radiotherapy for epithelial skin cancer was evaluated and treatment outcomes of two electron beam fractionation schedules were compared...
  16. ncbi Quality of life after pelvic radiotherapy or vaginal brachytherapy for endometrial cancer: first results of the randomized PORTEC-2 trial
    Remi A Nout
    Department of Clinical Oncology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Oncol 27:3547-56. 2009
    ..Vaginal brachytherapy provides a better QOL, and should be the preferred treatment from a QOL perspective...
  17. ncbi Prognostic significance and interobserver variability of histologic grading systems for endometrial carcinoma
    Astrid N Scholten
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Cancer 100:764-72. 2004
    ..The authors analyzed and compared the prognostic significance and the interobserver variability of both grading systems and of the three criteria for the binary grading system...
  18. ncbi Chest wall irradiation with MLC-shaped photon and electron fields
    M Essers
    Division of Clinical Physics, University Hospital Rotterdam Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 48:1205-17. 2000
    ....
  19. ncbi Postoperative radiotherapy for Stage 1 endometrial carcinoma: long-term outcome of the randomized PORTEC trial with central pathology review
    Astrid N Scholten
    Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Radiat Oncol Biol Phys 63:834-8. 2005
    ..0001). CONCLUSIONS: In view of the significant locoregional control benefit, radiotherapy remains indicated in Stage I endometrial carcinoma patients with high-risk features for locoregional relapse...
  20. ncbi Conceptual equivalence and health-related quality of life: an exploratory study in Japanese and Dutch cancer patients
    W Chr Kleijn
    Medical Psychology, Leiden University Medical Center, P O Box 9555, 2300 RB, Leiden, The Netherlands
    Qual Life Res 15:1091-101. 2006
    ..Longitudinal studies are needed to examine the impact of specific symptoms on general quality of life...
  21. ncbi Nuclear beta-catenin is a molecular feature of type I endometrial carcinoma
    A N Scholten
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    J Pathol 201:460-5. 2003
    ....
  22. ncbi Radiotherapy and hyperthermia for treatment of primary locally advanced cervix cancer: results in 378 patients
    Martine Franckena
    Department of Radiation Oncology, Erasmus Medical Center, Rotterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 73:242-50. 2009
    ....
  23. ncbi Lymphadenectomy in apparent early-stage endometrial carcinoma: do numbers count?
    Carien L Creutzberg
    J Clin Oncol 23:3653-5. 2005
  24. ncbi GOG-99: ending the controversy regarding pelvic radiotherapy for endometrial carcinoma?
    Carien L Creutzberg
    Gynecol Oncol 92:740-3. 2004