C L Creutzberg

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint The morbidity of treatment for patients with Stage I endometrial cancer: results from a randomized trial
    C L Creutzberg
    Department of Radiation Oncology, University Hospital Rotterdam Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 51:1246-55. 2001
  2. doi request reprint Long-term clinical outcome of patients with soft tissue sarcomas treated with limb-sparing surgery and postoperative radiotherapy
    Joeke M Felderhof
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Acta Oncol 52:745-52. 2013
  3. ncbi request reprint Adjuvant chemotherapy for endometrial cancer: unproven
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Gynecol Cancer 20:1105-8. 2010
  4. pmc The role of radiotherapy in endometrial cancer: current evidence and trends
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, The Netherlands
    Curr Oncol Rep 13:472-8. 2011
  5. doi request reprint Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, The Netherlands
    Int J Radiat Oncol Biol Phys 81:e631-8. 2011
  6. ncbi request reprint Survival after relapse in patients with endometrial cancer: results from a randomized trial
    Carien L Creutzberg
    Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    Gynecol Oncol 89:201-9. 2003
  7. ncbi request reprint Outcome of high-risk stage IC, grade 3, compared with stage I endometrial carcinoma patients: the Postoperative Radiation Therapy in Endometrial Carcinoma Trial
    Carien L Creutzberg
    Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    J Clin Oncol 22:1234-41. 2004
  8. doi request reprint Adjuvant chemotherapy for endometrial cancer: unproven
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, RC Leiden, The Netherlands
    Int J Gynecol Cancer 20:S60-3. 2010
  9. ncbi request reprint Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma
    C L Creutzberg
    Department of Radiation Oncology, University Hospital Rotterdam Daniel den Hoed Cancer Center, The Netherlands
    Lancet 355:1404-11. 2000
  10. doi request reprint Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial
    R A Nout
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, Netherlands
    Lancet 375:816-23. 2010

Detail Information

Publications26

  1. ncbi request reprint The morbidity of treatment for patients with Stage I endometrial cancer: results from a randomized trial
    C L Creutzberg
    Department of Radiation Oncology, University Hospital Rotterdam Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 51:1246-55. 2001
    ..To compare the treatment complications for patients with Stage I endometrial cancer treated with surgery and pelvic radiotherapy (RT) or surgery alone in a multicenter randomized trial...
  2. doi request reprint Long-term clinical outcome of patients with soft tissue sarcomas treated with limb-sparing surgery and postoperative radiotherapy
    Joeke M Felderhof
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Acta Oncol 52:745-52. 2013
    ..To evaluate long-term local control, survival, radiation side effects and functional outcome after limb-sparing surgery followed by postoperative radiotherapy (RT) for soft tissue sarcoma (STS)...
  3. ncbi request reprint Adjuvant chemotherapy for endometrial cancer: unproven
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Gynecol Cancer 20:1105-8. 2010
    ..Toxicity and quality of life data are lacking. The role of adjuvant chemotherapy for endometrial carcinoma remains unproven. High-risk EC remains the challenge for further research...
  4. pmc The role of radiotherapy in endometrial cancer: current evidence and trends
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, The Netherlands
    Curr Oncol Rep 13:472-8. 2011
    ..Current ongoing trials are exploring the role of combined RT and chemotherapy, compared to chemotherapy or RT alone...
  5. doi request reprint Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, The Netherlands
    Int J Radiat Oncol Biol Phys 81:e631-8. 2011
    ....
  6. ncbi request reprint Survival after relapse in patients with endometrial cancer: results from a randomized trial
    Carien L Creutzberg
    Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    Gynecol Oncol 89:201-9. 2003
    ..The aim of this study was to determine the rates of local control and survival after relapse in patients with stage I endometrial cancer treated in the multicenter randomized PORTEC trial...
  7. ncbi request reprint Outcome of high-risk stage IC, grade 3, compared with stage I endometrial carcinoma patients: the Postoperative Radiation Therapy in Endometrial Carcinoma Trial
    Carien L Creutzberg
    Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    J Clin Oncol 22:1234-41. 2004
    ..Stage IC, grade 3 patients were not eligible for the randomized Postoperative Radiation Therapy in Endometrial Carcinoma (PORTEC) trial, but were registered and received postoperative radiotherapy...
  8. doi request reprint Adjuvant chemotherapy for endometrial cancer: unproven
    Carien L Creutzberg
    Department of Clinical Oncology, Leiden University Medical Center, RC Leiden, The Netherlands
    Int J Gynecol Cancer 20:S60-3. 2010
    ..Toxicity and quality-of-life data are lacking. The role of adjuvant chemotherapy for endometrial carcinoma remains unproven. High-risk EC remains the challenge for further research...
  9. ncbi request reprint Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma
    C L Creutzberg
    Department of Radiation Oncology, University Hospital Rotterdam Daniel den Hoed Cancer Center, The Netherlands
    Lancet 355:1404-11. 2000
    ..We did a multicentre prospective randomised trial to find whether postoperative pelvic radiotherapy improves locoregional control and survival for patients with stage-1 endometrial carcinoma...
  10. doi request reprint Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial
    R A Nout
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, Netherlands
    Lancet 375:816-23. 2010
    ..This study established whether vaginal brachytherapy (VBT) is as effective as pelvic external beam radiotherapy (EBRT) in prevention of vaginal recurrence, with fewer adverse effects and improved quality of life...
  11. ncbi request reprint Postoperative radiation therapy improves prognosis in patients with adverse risk factors in localized, early-stage cervical cancer: a retrospective comparative study
    Q D Pieterse
    Department of Gynaecology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Int J Gynecol Cancer 16:1112-8. 2006
    ..HR patients benefit from adjuvant RT. The LUMC modification of the GOG system seems to be simpler and has a slightly higher threshold for the indication for RT but without a difference in outcome...
  12. ncbi request reprint Combined E-cadherin, alpha-catenin, and beta-catenin expression is a favorable prognostic factor in endometrial carcinoma
    A N Scholten
    Department of Clinical Oncology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Int J Gynecol Cancer 16:1379-85. 2006
    ..02). Negative E-cadherin expression was found to be associated with histologic grade 3 and with NEEC. Combined positive E-cadherin, alpha-catenin, and beta-catenin expression was a significant prognostic factor...
  13. ncbi request reprint Chest wall irradiation with MLC-shaped photon and electron fields
    M Essers
    Division of Clinical Physics, University Hospital Rotterdam Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 48:1205-17. 2000
    ....
  14. ncbi request reprint [Is there an indication for additional local irradiation in conserving treatment of breast cancer patients aged 60 and over?]
    E M Noordijk
    Leids Universitair Medisch Centrum, afd Klinische Oncologie, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 146:395-8. 2002
    ..0%). Therefore it is questionable whether an additional dose of 16 Gy (reducing the recurrence rate to 2.5%) is still justified as a standard treatment in this age group...
  15. ncbi request reprint Prognostic significance and interobserver variability of histologic grading systems for endometrial carcinoma
    Astrid N Scholten
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Cancer 100:764-72. 2004
    ..The authors analyzed and compared the prognostic significance and the interobserver variability of both grading systems and of the three criteria for the binary grading system...
  16. ncbi request reprint Long-term outcome in endometrial carcinoma favors a two- instead of a three-tiered grading system
    Astrid N Scholten
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Radiat Oncol Biol Phys 52:1067-74. 2002
    ..A retrospective analysis of long-term outcome and predictive factors in endometrial carcinoma was conducted, focusing on the prognostic value of tumor grade...
  17. doi request reprint Quality of life after pelvic radiotherapy or vaginal brachytherapy for endometrial cancer: first results of the randomized PORTEC-2 trial
    Remi A Nout
    Department of Clinical Oncology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Oncol 27:3547-56. 2009
    ..Vaginal brachytherapy provides a better QOL, and should be the preferred treatment from a QOL perspective...
  18. doi request reprint Long-term outcome and quality of life of patients with endometrial carcinoma treated with or without pelvic radiotherapy in the post operative radiation therapy in endometrial carcinoma 1 (PORTEC-1) trial
    Remi A Nout
    Department of Clinical Oncology, Leiden University Medical Center, PO PO Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Oncol 29:1692-700. 2011
    ....
  19. doi request reprint Efficacy of a hypofractionated schedule in electron beam radiotherapy for epithelial skin cancer: Analysis of 434 cases
    Marjan van Hezewijk
    Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Radiother Oncol 95:245-9. 2010
    ..Efficacy of radiotherapy for epithelial skin cancer was evaluated and treatment outcomes of two electron beam fractionation schedules were compared...
  20. ncbi request reprint Postoperative radiotherapy for Stage 1 endometrial carcinoma: long-term outcome of the randomized PORTEC trial with central pathology review
    Astrid N Scholten
    Department of Radiation Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Radiat Oncol Biol Phys 63:834-8. 2005
    ..Radiotherapy significantly decreased the risk of locoregional recurrence (4% vs. 14%), without affecting overall survival. In this report the long-term outcome and results with central pathology review are presented...
  21. pmc Chronic fatigue in Hodgkin lymphoma survivors and associations with anxiety, depression and comorbidity
    L A Daniels
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    Br J Cancer 110:868-74. 2014
    ..Fatigue is a frequent and persistent problem among Hodgkin lymphoma (HL) survivors. We investigated the prevalence of clinically relevant fatigue in HL survivors and the relation between fatigue and anxiety and depression...
  22. ncbi request reprint Nuclear beta-catenin is a molecular feature of type I endometrial carcinoma
    A N Scholten
    Department of Clinical Oncology, Leiden University Medical Center, Leiden, The Netherlands
    J Pathol 201:460-5. 2003
    ....
  23. ncbi request reprint Conceptual equivalence and health-related quality of life: an exploratory study in Japanese and Dutch cancer patients
    W Chr Kleijn
    Medical Psychology, Leiden University Medical Center, P O Box 9555, 2300 RB, Leiden, The Netherlands
    Qual Life Res 15:1091-101. 2006
    ..Longitudinal studies are needed to examine the impact of specific symptoms on general quality of life...
  24. doi request reprint Radiotherapy and hyperthermia for treatment of primary locally advanced cervix cancer: results in 378 patients
    Martine Franckena
    Department of Radiation Oncology, Erasmus Medical Center, Rotterdam, The Netherlands
    Int J Radiat Oncol Biol Phys 73:242-50. 2009
    ....
  25. ncbi request reprint GOG-99: ending the controversy regarding pelvic radiotherapy for endometrial carcinoma?
    Carien L Creutzberg
    Gynecol Oncol 92:740-3. 2004
  26. ncbi request reprint Lymphadenectomy in apparent early-stage endometrial carcinoma: do numbers count?
    Carien L Creutzberg
    J Clin Oncol 23:3653-5. 2005