Paul L A M Corstjens

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. pmc Development of a generic microfluidic device for simultaneous detection of antibodies and nucleic acids in oral fluids
    Zongyuan Chen
    Rheonix, Inc, Ithaca, NY 14850, USA
    Biomed Res Int 2013:543294. 2013
  2. doi request reprint A rapid assay for on-site monitoring of infliximab trough levels: a feasibility study
    Paul L A M Corstjens
    Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20 Bldg 2, PO Box 9600, 2300 RC, Leiden, The Netherlands
    Anal Bioanal Chem 405:7367-75. 2013
  3. pmc Lateral flow assay for simultaneous detection of cellular- and humoral immune responses
    Paul L A M Corstjens
    Department of Molecular Cell Biology Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands
    Clin Biochem 44:1241-6. 2011
  4. pmc A robust dry reagent lateral flow assay for diagnosis of active schistosomiasis by detection of Schistosoma circulating anodic antigen
    Govert J van Dam
    Department of Parasitology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Exp Parasitol 135:274-82. 2013
  5. ncbi request reprint An amplification-free hybridization-based DNA assay to detect Streptococcus pneumoniae utilizing the up-converting phosphor technology
    Michel Zuiderwijk
    Laboratory for Cytochemistry and Cytometry, Department of Molecular Cell Biology, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands
    Clin Biochem 36:401-3. 2003
  6. ncbi request reprint Rapid assay format for multiplex detection of humoral immune responses to infectious disease pathogens (HIV, HCV, and TB)
    Paul L A M Corstjens
    Department of Molecular Cell Biology, Leiden University Medical Center, RC Leiden, The Netherlands
    Ann N Y Acad Sci 1098:437-45. 2007
  7. pmc A user-friendly, highly sensitive assay to detect the IFN-gamma secretion by T cells
    Paul L A M Corstjens
    Leiden University Medical Center, Department of Molecular Cell Biology, Leiden, The Netherlands
    Clin Biochem 41:440-4. 2008
  8. ncbi request reprint Detecting viruses by using salivary diagnostics
    Paul L A M Corstjens
    Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, Netherlands
    J Am Dent Assoc 143:12S-8S. 2012
  9. ncbi request reprint Feasibility of a lateral flow test for neurocysticercosis using novel up-converting nanomaterials and a lightweight strip analyzer
    Paul L A M Corstjens
    Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands
    PLoS Negl Trop Dis 8:e2944. 2014
  10. pmc Up-converting phosphor technology-based lateral flow assay for detection of Schistosoma circulating anodic antigen in serum
    Paul L A M Corstjens
    Leiden University Medical Center, Department of Molecular Cell Biology, Bldg 2, S 01 030, P O Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Microbiol 46:171-6. 2008

Collaborators

Detail Information

Publications12

  1. pmc Development of a generic microfluidic device for simultaneous detection of antibodies and nucleic acids in oral fluids
    Zongyuan Chen
    Rheonix, Inc, Ithaca, NY 14850, USA
    Biomed Res Int 2013:543294. 2013
    ..The serological result is available in less than 30 min, and the confirmation by RNA amplification takes another 60 min. This approach combines a core serological portable diagnostic with a nucleic acid-based confirmatory test...
  2. doi request reprint A rapid assay for on-site monitoring of infliximab trough levels: a feasibility study
    Paul L A M Corstjens
    Department of Molecular Cell Biology, Leiden University Medical Center, Einthovenweg 20 Bldg 2, PO Box 9600, 2300 RC, Leiden, The Netherlands
    Anal Bioanal Chem 405:7367-75. 2013
    ..Because of its generic nature, the assay is suited for detecting most therapeutic anti-TNF-α monoclonal antibodies. ..
  3. pmc Lateral flow assay for simultaneous detection of cellular- and humoral immune responses
    Paul L A M Corstjens
    Department of Molecular Cell Biology Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands
    Clin Biochem 44:1241-6. 2011
    ..The development of a cytokine detection assay suitable for detection of multiple biomarkers for improved diagnosis of mycobacterial diseases...
  4. pmc A robust dry reagent lateral flow assay for diagnosis of active schistosomiasis by detection of Schistosoma circulating anodic antigen
    Govert J van Dam
    Department of Parasitology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    Exp Parasitol 135:274-82. 2013
    ....
  5. ncbi request reprint An amplification-free hybridization-based DNA assay to detect Streptococcus pneumoniae utilizing the up-converting phosphor technology
    Michel Zuiderwijk
    Laboratory for Cytochemistry and Cytometry, Department of Molecular Cell Biology, Leiden University Medical Center, Wassenaarseweg 72, 2333 AL Leiden, The Netherlands
    Clin Biochem 36:401-3. 2003
    ..Development of a generally applicable sensitive hybridization-based assay devoid of any target amplification for the detection and identification of (pathogenic) bacterial and viral species...
  6. ncbi request reprint Rapid assay format for multiplex detection of humoral immune responses to infectious disease pathogens (HIV, HCV, and TB)
    Paul L A M Corstjens
    Department of Molecular Cell Biology, Leiden University Medical Center, RC Leiden, The Netherlands
    Ann N Y Acad Sci 1098:437-45. 2007
    ..The bench-top CF format was converted to a microfluidic platform and a first prototype semiautomated chip capable of performing CF is presented here...
  7. pmc A user-friendly, highly sensitive assay to detect the IFN-gamma secretion by T cells
    Paul L A M Corstjens
    Leiden University Medical Center, Department of Molecular Cell Biology, Leiden, The Netherlands
    Clin Biochem 41:440-4. 2008
    ..Development of a user-friendly test alternative to ELISA-based assays to detect IFN-gamma by in vitro cultured peripheral blood mononuclear cells (PBMC) stimulated with pathogen-derived antigens...
  8. ncbi request reprint Detecting viruses by using salivary diagnostics
    Paul L A M Corstjens
    Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, Netherlands
    J Am Dent Assoc 143:12S-8S. 2012
    ....
  9. ncbi request reprint Feasibility of a lateral flow test for neurocysticercosis using novel up-converting nanomaterials and a lightweight strip analyzer
    Paul L A M Corstjens
    Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands
    PLoS Negl Trop Dis 8:e2944. 2014
    ....
  10. pmc Up-converting phosphor technology-based lateral flow assay for detection of Schistosoma circulating anodic antigen in serum
    Paul L A M Corstjens
    Leiden University Medical Center, Department of Molecular Cell Biology, Bldg 2, S 01 030, P O Box 9600, 2300 RC Leiden, The Netherlands
    J Clin Microbiol 46:171-6. 2008
    ..In conclusion, the UPT-LF assay is a low-complexity test with higher sensitivity than the CAA-ELISA, well suited for laboratory diagnosis of individual active Schistosoma infections...
  11. pmc Field-evaluation of a new lateral flow assay for detection of cellular and humoral immunity against Mycobacterium leprae
    Kidist Bobosha
    Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands Armauer Hansen Research Institute, Addis Ababa, Ethiopia
    PLoS Negl Trop Dis 8:e2845. 2014
    ..leprae. Previously, we developed lateral flow assays (LFA) for detection of cytokines and anti-PGL-I antibodies. Here we evaluate progress of newly developed LFAs for applications in resource-poor settings...
  12. ncbi request reprint Lateral-flow and up-converting phosphor reporters to detect single-stranded nucleic acids in a sandwich-hybridization assay
    Paul L A M Corstjens
    Laboratory for Cytochemistry and Cytometry, Department of Molecular Cell Biology, Leiden University Medical Center, Wassenaarseweg 72, The Netherlands
    Anal Biochem 312:191-200. 2003
    ..With the assay described here as little as 0.1 fmol of a specific single-stranded nucleic acid target was detected in a background of 10 microg fish sperm DNA...