Madelon M Buijs

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Hyposomatotropism blunts lipolysis in abdominally obese women
    Madelon M Buijs
    Department of General Internal Medicine, Leiden University Medical Centre, Leiden 2300 RC, The Netherlands
    J Clin Endocrinol Metab 87:3851-8. 2002
  2. ncbi request reprint Blunted lipolytic response to fasting in abdominally obese women: evidence for involvement of hyposomatotropism
    Madelon M Buijs
    Department of General Internal Medicine, Leiden University Medical Center, Leiden, Netherlands
    Am J Clin Nutr 77:544-50. 2003
  3. ncbi request reprint Enhanced circadian ACTH release in obese premenopausal women: reversal by short-term acipimox treatment
    Petra Kok
    Department of General Internal Medicine, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Am J Physiol Endocrinol Metab 287:E848-56. 2004
  4. ncbi request reprint Growth hormone blunts protein oxidation and promotes protein turnover to a similar extent in abdominally obese and normal-weight women
    Madelon M Buijs
    Department of General Internal Medicine, Leiden University Medical Centre, 2300 RC Leiden, The Netherlands
    J Clin Endocrinol Metab 87:5668-74. 2002
  5. ncbi request reprint Renal contribution to increased clearance of exogenous growth hormone in obese hypertensive patients
    Madelon M Buijs
    Department of General Internal Medicine, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    J Clin Endocrinol Metab 90:795-9. 2005
  6. ncbi request reprint Acipimox enhances spontaneous growth hormone secretion in obese women
    Petra Kok
    Department of General Internal Medicine, Leiden University Medical Center, C4 83, PO Box 9600, 2300 RC Leiden, The Netherlands
    Am J Physiol Regul Integr Comp Physiol 286:R693-8. 2004
  7. ncbi request reprint Modeling the influence of growth hormone on lipolysis
    Rik C Schoemaker
    Centre for Human Drug Research, Leiden University Medical Center, The Netherlands
    J Pharmacokinet Pharmacodyn 29:157-70. 2002

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Hyposomatotropism blunts lipolysis in abdominally obese women
    Madelon M Buijs
    Department of General Internal Medicine, Leiden University Medical Centre, Leiden 2300 RC, The Netherlands
    J Clin Endocrinol Metab 87:3851-8. 2002
    ..06, OB: 0.68, P > 0.05). These results suggest that hyposomatotropism in abdominally obese individuals is not compensated by increased adipose tissue responsiveness to GH bio-action and, therefore, blunts lipolysis in these individuals...
  2. ncbi request reprint Blunted lipolytic response to fasting in abdominally obese women: evidence for involvement of hyposomatotropism
    Madelon M Buijs
    Department of General Internal Medicine, Leiden University Medical Center, Leiden, Netherlands
    Am J Clin Nutr 77:544-50. 2003
    ..Abdominal obesity is associated with a blunted lipolytic response to fasting that may contribute to the preservation of adipose tissue mass...
  3. ncbi request reprint Enhanced circadian ACTH release in obese premenopausal women: reversal by short-term acipimox treatment
    Petra Kok
    Department of General Internal Medicine, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Am J Physiol Endocrinol Metab 287:E848-56. 2004
    ..Reduction of circulating FFA concentrations by acipimox blunts ACTH release in obese women, which suggests that FFAs are involved in the pathophysiology of this neuroendocrine anomaly...
  4. ncbi request reprint Growth hormone blunts protein oxidation and promotes protein turnover to a similar extent in abdominally obese and normal-weight women
    Madelon M Buijs
    Department of General Internal Medicine, Leiden University Medical Centre, 2300 RC Leiden, The Netherlands
    J Clin Endocrinol Metab 87:5668-74. 2002
    ..However, hyposomatotropism cannot account for all anomalous features of protein metabolism in abdominally obese humans...
  5. ncbi request reprint Renal contribution to increased clearance of exogenous growth hormone in obese hypertensive patients
    Madelon M Buijs
    Department of General Internal Medicine, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    J Clin Endocrinol Metab 90:795-9. 2005
    ..These results suggest that RFEGH rises with increasing adiposity, but per unit of renal mass, the capacity of the kidney to remove GH from the circulation falls at high MCR values...
  6. ncbi request reprint Acipimox enhances spontaneous growth hormone secretion in obese women
    Petra Kok
    Department of General Internal Medicine, Leiden University Medical Center, C4 83, PO Box 9600, 2300 RC Leiden, The Netherlands
    Am J Physiol Regul Integr Comp Physiol 286:R693-8. 2004
    ..It specifically enhances GH secretory burst mass. This might mean that lowering of systemic FFA concentrations by acipimox modulates neuroendocrine mechanisms that orchestrate the activity of the somatotropic ensemble...
  7. ncbi request reprint Modeling the influence of growth hormone on lipolysis
    Rik C Schoemaker
    Centre for Human Drug Research, Leiden University Medical Center, The Netherlands
    J Pharmacokinet Pharmacodyn 29:157-70. 2002
    ..Modeling allowed the assessment of potential differences in GH sensitivity in the two groups, and indicated the importance of GH in lipolysis...