R J Berckmans

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation
    R J Berckmans
    Department of Clinical Chemistry, Leiden University Medical Center, The Netherlands
    Thromb Haemost 85:639-46. 2001
  2. ncbi request reprint Cellular origin and procoagulant properties of microparticles in meningococcal sepsis
    R Nieuwland
    Department of Clinical Chemistry, Leiden University Medical Center, Leiden, The Netherlands
    Blood 95:930-5. 2000
  3. ncbi request reprint Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant
    R Nieuwland
    Department of Clinical Chemistry, University Hospital Leiden, The Netherlands
    Circulation 96:3534-41. 1997
  4. ncbi request reprint Microparticles from patients with multiple organ dysfunction syndrome and sepsis support coagulation through multiple mechanisms
    K Joop
    Department of Clinical Chemistry, Leiden University Medical Center, The Netherlands
    Thromb Haemost 85:810-20. 2001

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation
    R J Berckmans
    Department of Clinical Chemistry, Leiden University Medical Center, The Netherlands
    Thromb Haemost 85:639-46. 2001
    ..We conclude that microparticles in blood from healthy individuals support thrombin generation via TF- and FVII-independent pathways, and which may have an anticoagulant function...
  2. ncbi request reprint Cellular origin and procoagulant properties of microparticles in meningococcal sepsis
    R Nieuwland
    Department of Clinical Chemistry, Leiden University Medical Center, Leiden, The Netherlands
    Blood 95:930-5. 2000
    ..These findings may suggest a novel therapeutic approach to combat clinical conditions with excessive coagulation activation...
  3. ncbi request reprint Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant
    R Nieuwland
    Department of Clinical Chemistry, University Hospital Leiden, The Netherlands
    Circulation 96:3534-41. 1997
    ..The aim of the present study was to investigate the procoagulant properties of microparticles generated in vivo...
  4. ncbi request reprint Microparticles from patients with multiple organ dysfunction syndrome and sepsis support coagulation through multiple mechanisms
    K Joop
    Department of Clinical Chemistry, Leiden University Medical Center, The Netherlands
    Thromb Haemost 85:810-20. 2001
    ..62, p = 0.013). CONCLUSIONS: In patients with MODS and sepsis relatively low numbers of MP are present that differ from controls in their cellular origin, numbers and coagulation activation mechanisms...