J J Bax

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. pmc Left ventricular dyssynchrony assessed by two three-dimensional imaging modalities: phase analysis of gated myocardial perfusion SPECT and tri-plane tissue Doppler imaging
    Nina Ajmone Marsan
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333, ZA, Leiden, The Netherlands
    Eur J Nucl Med Mol Imaging 35:166-73. 2008
  2. ncbi request reprint Restrictive annuloplasty and coronary revascularization in ischemic mitral regurgitation results in reverse left ventricular remodeling
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Circulation 110:II103-8. 2004
  3. ncbi request reprint Non-compaction cardiomyopathy-echocardiographic diagnosis
    J J Bax
    Department of Cardiology, Leiden University Medical Center, The Netherlands
    Eur J Echocardiogr 3:301-2. 2002
  4. ncbi request reprint Noninvasive and invasive evaluation of noncompaction cardiomyopathy
    Jeroen J Bax
    J Cardiovasc Magn Reson 4:353-7. 2002
  5. ncbi request reprint Perfusion and contractile reserve in chronic dysfunctional myocardium: relation to functional outcome after surgical revascularization
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Circulation 106:I14-8. 2002
  6. ncbi request reprint Safety and feasibility of cardiac FDG SPECT following oral administration of Acipimox, a nicotinic acid derivative: Comparison of image quality with hyperinsulinemic euglycemic clamping in nondiabetic patients
    Jeroen J Bax
    Leiden University Medical Center, Leiden, Free University Hospital, Amsterdam, The Netherlands
    J Nucl Cardiol 9:587-93. 2002
  7. ncbi request reprint Prognostic value of perfusion-FDG mismatch in ischemic cardiomyopathy
    Jeroen J Bax
    Leiden University Medical Center, Leiden, Free University Hospital, Amsterdam, Thorax Center, Rotterdam, The Netherlands
    J Nucl Cardiol 9:675-7. 2002
  8. ncbi request reprint Can molecular imaging predict in-stent restenosis?
    Jeroen J Bax
    Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    J Nucl Med 45:300-1. 2004
  9. ncbi request reprint Imaging to differentiate between ischemic and nonischemic cardiomyopathy
    Jeroen J Bax
    Leiden University Medical Center, Leiden, The Netherlands
    Heart Fail Clin 2:205-14. 2006
  10. ncbi request reprint FDG imaging should be considered the preferred technique for accurate assessment of myocardial viability: for
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands
    Eur J Nucl Med Mol Imaging 32:829-31. 2005

Detail Information

Publications158 found, 100 shown here

  1. pmc Left ventricular dyssynchrony assessed by two three-dimensional imaging modalities: phase analysis of gated myocardial perfusion SPECT and tri-plane tissue Doppler imaging
    Nina Ajmone Marsan
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333, ZA, Leiden, The Netherlands
    Eur J Nucl Med Mol Imaging 35:166-73. 2008
    ..Information on LV dyssynchrony can also be provided by GMPS with phase analysis of regional LV maximal count changes throughout the cardiac cycle...
  2. ncbi request reprint Restrictive annuloplasty and coronary revascularization in ischemic mitral regurgitation results in reverse left ventricular remodeling
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Circulation 110:II103-8. 2004
    ..Data on combined coronary artery bypass grafting (CABG) and restrictive annuloplasty in patients with ischemic cardiomyopathy are scarce, and the effect on reverse left ventricular (LV) remodeling is unknown...
  3. ncbi request reprint Non-compaction cardiomyopathy-echocardiographic diagnosis
    J J Bax
    Department of Cardiology, Leiden University Medical Center, The Netherlands
    Eur J Echocardiogr 3:301-2. 2002
    ..Long-term prognosis is poor. Echocardiography is used to confirm the diagnosis; in the current case-report, we describe the typical abnormalities observed on echocardiography in a patient with non-compaction cardiomyopathy...
  4. ncbi request reprint Noninvasive and invasive evaluation of noncompaction cardiomyopathy
    Jeroen J Bax
    J Cardiovasc Magn Reson 4:353-7. 2002
    ..Long-term prognosis is poor. Currently, diagnosis is based on findings on 2D echocardiography; in the current case report we demonstrate the use of MRI to diagnose noncompaction cardiomyopathy...
  5. ncbi request reprint Perfusion and contractile reserve in chronic dysfunctional myocardium: relation to functional outcome after surgical revascularization
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Circulation 106:I14-8. 2002
    ....
  6. ncbi request reprint Safety and feasibility of cardiac FDG SPECT following oral administration of Acipimox, a nicotinic acid derivative: Comparison of image quality with hyperinsulinemic euglycemic clamping in nondiabetic patients
    Jeroen J Bax
    Leiden University Medical Center, Leiden, Free University Hospital, Amsterdam, The Netherlands
    J Nucl Cardiol 9:587-93. 2002
    ..However, the approach is time-consuming. Data in a small number of patients suggest that oral administration of a nicotinic acid derivative (Acipimox, 250 mg; Byk, The Netherlands) results in good image quality...
  7. ncbi request reprint Prognostic value of perfusion-FDG mismatch in ischemic cardiomyopathy
    Jeroen J Bax
    Leiden University Medical Center, Leiden, Free University Hospital, Amsterdam, Thorax Center, Rotterdam, The Netherlands
    J Nucl Cardiol 9:675-7. 2002
  8. ncbi request reprint Can molecular imaging predict in-stent restenosis?
    Jeroen J Bax
    Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    J Nucl Med 45:300-1. 2004
  9. ncbi request reprint Imaging to differentiate between ischemic and nonischemic cardiomyopathy
    Jeroen J Bax
    Leiden University Medical Center, Leiden, The Netherlands
    Heart Fail Clin 2:205-14. 2006
  10. ncbi request reprint FDG imaging should be considered the preferred technique for accurate assessment of myocardial viability: for
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands
    Eur J Nucl Med Mol Imaging 32:829-31. 2005
  11. ncbi request reprint The potential of myocardial perfusion scintigraphy for risk stratification of asymptomatic patients with type 2 diabetes
    Jeroen J Bax
    Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 48:754-60. 2006
    ....
  12. ncbi request reprint Cardiac resynchronization therapy: Part 2--issues during and after device implantation and unresolved questions
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 46:2168-82. 2005
    ..Finally, open questions concerning when to combine CRT with implantable cardioverter-defibrillator therapy and the cost-effectiveness of CRT are discussed...
  13. ncbi request reprint Preoperative comparison of different noninvasive strategies for predicting improvement in left ventricular function after coronary artery bypass grafting
    Jeroen J Bax
    Department of Cardiology, University Hospital Leiden, Leiden, The Netherlands
    Am J Cardiol 92:1-4. 2003
    ..In centers without access to FDG, sequential imaging with Tl-201 and DSE offers an accurate alternative for assessing myocardial viability...
  14. ncbi request reprint Left ventricular dyssynchrony predicts benefit of cardiac resynchronization therapy in patients with end-stage heart failure before pacemaker implantation
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Am J Cardiol 92:1238-40. 2003
    ..The presence of left ventricular dyssynchrony is needed to result in improvement after cardiac resynchronization therapy...
  15. ncbi request reprint Early versus delayed revascularization in patients with ischemic cardiomyopathy and substantial viability: impact on outcome
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, The Netherlands
    Circulation 108:II39-42. 2003
    ..Delayed revascularization may result in less favorable outcome, and therefore the impact of timing of revascularization on long-term outcome was evaluated...
  16. ncbi request reprint Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy
    Jeroen J Bax
    Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 44:1834-40. 2004
    ..This study was designed to predict the response and prognosis after cardiac resynchronization therapy (CRT) in patients with end-stage heart failure (HF)...
  17. ncbi request reprint Feasibility, safety and image quality of cardiac FDG studies during hyperinsulinaemic-euglycaemic clamping
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Eur J Nucl Med Mol Imaging 29:452-7. 2002
    ..It is concluded that cardiac FDG imaging during clamping is safe and provides excellent image quality, including in patients with diabetes mellitus. The incidence of viability is high, in particular in patients with diabetes mellitus...
  18. ncbi request reprint Time course of functional recovery of stunned and hibernating segments after surgical revascularization
    J J Bax
    Department of Cardiology, Leiden University Medical Center, Leiden
    Circulation 104:I314-8. 2001
    ..Accordingly, the time courses of functional recovery in hibernating and stunned myocardium were compared...
  19. ncbi request reprint Echocardiographic evaluation of cardiac resynchronization therapy: ready for routine clinical use? A critical appraisal
    Jeroen J Bax
    Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 44:1-9. 2004
    ..In the current review, the different echocardiographic approaches to predict response to CRT are discussed. In addition, the use of echocardiography to guide LV lead positioning and follow-up after CRT are addressed...
  20. ncbi request reprint Cardiac resynchronization therapy: Part 1--issues before device implantation
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 46:2153-67. 2005
    ..In addition, the value of LV scar tissue and venous anatomy for the selection of potential candidates for CRT are discussed...
  21. pmc Radionuclide techniques for the assessment of myocardial viability and hibernation
    J J Bax
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Heart 90:v26-33. 2004
  22. ncbi request reprint Sequential (201)Tl imaging and dobutamine echocardiography to enhance accuracy of predicting improved left ventricular ejection fraction after revascularization
    Jeroen J Bax
    Department of Cardiology, University Hospital Leiden, Leiden, The Netherlands
    J Nucl Med 43:795-802. 2002
    ..This study was undertaken to develop an optimal testing strategy for prediction of post-revascularization functional outcome...
  23. ncbi request reprint Extensive left ventricular remodeling does not allow viable myocardium to improve in left ventricular ejection fraction after revascularization and is associated with worse long-term prognosis
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Circulation 110:II18-22. 2004
    ..Extensive left ventricular (LV) remodeling may not allow functional recovery after revascularization, despite the presence of viable myocardium...
  24. doi request reprint Asymptomatic low ankle-brachial index in vascular surgery patients: a predictor of perioperative myocardial damage
    W J Flu
    Department of Anesthesiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur J Vasc Endovasc Surg 39:62-9. 2010
    ....
  25. ncbi request reprint A combination of statins and beta-blockers is independently associated with a reduction in the incidence of perioperative mortality and nonfatal myocardial infarction in patients undergoing abdominal aortic aneurysm surgery
    M D Kertai
    Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands
    Eur J Vasc Endovasc Surg 28:343-52. 2004
    ..To investigate the combined beneficial effect of statin and beta-blocker use on perioperative mortality and myocardial infarction (MI) in patients undergoing abdominal aortic aneurysm surgery (AAA)...
  26. pmc Pulsed wave tissue Doppler imaging for the quantification of contractile reserve in stunned, hibernating, and scarred myocardium
    M Bountioukos
    Thoraxcenter, Department of Cardiology, Erasmus MC, Rotterdam, Netherlands
    Heart 90:506-10. 2004
    ..To assess whether quantification of myocardial systolic velocities by pulsed wave tissue Doppler imaging can differentiate between stunned, hibernating, and scarred myocardium...
  27. ncbi request reprint Relationship between preoperative viability and postoperative improvement in LVEF and heart failure symptoms
    J J Bax
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    J Nucl Med 42:79-86. 2001
    ..CONCLUSION: The presence of substantial viability (four or more viable segments, 31% of the left ventricle) on FDG SPECT is predictive of improvement in LVEF and heart failure symptoms postoperatively...
  28. pmc Outcome after redo coronary artery bypass grafting in patients with ischaemic cardiomyopathy and viable myocardium
    V Rizzello
    Department of Cardiology, Thorax Center Room Ba 300, Erasmus MC, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Heart 93:221-5. 2007
    ..Repeat coronary artery bypass grafting (redo-CABG) in patients with ischaemic cardiomyopathy is associated with high perioperative risk and worse long-term outcome compared with patients undergoing their first CABG...
  29. pmc Performance and efficacy of 320-row computed tomography coronary angiography in patients presenting with acute chest pain: results from a clinical registry
    J E van Velzen
    Department of Cardiology, Leiden University Medical Center, Postal Zone C5 P, P O Box 9600, 2333 ZA, Leiden, The Netherlands
    Int J Cardiovasc Imaging 28:865-76. 2012
    ..Importantly, normal or non-significant CAD on CTA predicted a low rate of adverse cardiovascular events and favorable outcome during follow-up...
  30. pmc Relation between regional and global systolic function in patients with ischemic cardiomyopathy after beta-blocker therapy or revascularization
    T A M Kaandorp
    Department of Radiology, Leiden University Medical Center, The Netherlands
    J Cardiovasc Magn Reson 12:7. 2010
    ..To assess the relationship between improved regional and global myocardial function in patients with ischemic cardiomyopathy in response to beta-blocker therapy or revascularization...
  31. ncbi request reprint Accuracy of currently available techniques for prediction of functional recovery after revascularization in patients with left ventricular dysfunction due to chronic coronary artery disease: comparison of pooled data
    J J Bax
    Department of Cardiology, Academic Hospital, Leiden, The Netherlands
    J Am Coll Cardiol 30:1451-60. 1997
    ....
  32. doi request reprint Prognosis of vascular surgery patients using a quantitative assessment of troponin T release: is the crystal ball still clear?
    T A Winkel
    Department of Vascular Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur J Vasc Endovasc Surg 40:739-46. 2010
    ..We compared the prognosis of vascular surgery patients with integrated cTnT-AUC values to continuous and standard 12-lead electrocardiography (ECG) changes...
  33. pmc Improvement of stress LVEF rather than rest LVEF after coronary revascularisation in patients with ischaemic cardiomyopathy and viable myocardium
    V Rizzello
    Department of Cardiology, Thoraxcentre, Erasmus MC, Rotterdam, The Netherlands
    Heart 91:319-23. 2005
    ..To evaluate prospectively the response of left ventricular ejection fraction (LVEF) to high dose dobutamine infusion in patients showing substantial viability, with and without improved resting LVEF after revascularisation...
  34. ncbi request reprint Advanced applications of 3-dimensional echocardiography
    A C T Ng
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Minerva Cardioangiol 57:415-41. 2009
    ....
  35. ncbi request reprint Comparison of gated single-photon emission computed tomography with magnetic resonance imaging for evaluation of left ventricular function in ischemic cardiomyopathy
    J J Bax
    Department of Cardiology, Leiden University Medical Center, The Netherlands
    Am J Cardiol 86:1299-305. 2000
    ..83, SE 0.03), indicating essentially excellent agreement. Thus, close and significant correlations were observed for assessment of LVEF, LV volumes, and regional wall motion by MRI and gated SPECT in patients with ischemic cardiomyopathy...
  36. ncbi request reprint Improvement of left ventricular ejection fraction, heart failure symptoms and prognosis after revascularization in patients with chronic coronary artery disease and viable myocardium detected by dobutamine stress echocardiography
    J J Bax
    Department of Cardiology, University Hospital Leiden, The Netherlands
    J Am Coll Cardiol 34:163-9. 1999
    ....
  37. ncbi request reprint Beta-blockers improve outcomes in kidney disease patients having noncardiac vascular surgery
    G M J M Welten
    Department of Vascular Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
    Kidney Int 72:1527-34. 2007
    ..This study shows that kidney function is a predictor of all-cause mortality and beta-blocker use is associated with a lower risk of death in kidney disease patients undergoing elective vascular surgery...
  38. doi request reprint Prognosis of transient new-onset atrial fibrillation during vascular surgery
    T A Winkel
    Department of Vascular Surgery, Erasmus MC, s Gravendijkwal 230, Rotterdam, The Netherlands
    Eur J Vasc Endovasc Surg 38:683-8. 2009
    ..Chronic atrial fibrillation (AF) in a non-surgical setting is associated with cardiovascular events. However, the prognosis of transient new-onset AF during vascular surgery is unknown...
  39. ncbi request reprint Effect of coronary artery bypass surgery on myocardial perfusion and ejection fraction response to inotropic stimulation in patients without improvement in resting ejection fraction
    A Elhendy
    Thoraxcenter, Rotterdam, The Netherlands
    Am J Cardiol 86:490-4. 2000
    ..We describe the myocardium with these characteristics as "the reactive myocardium."..
  40. ncbi request reprint Perioperative cardiac risk stratification and modification in abdominal aortic aneurysm repair
    M Dunkelgrun
    Vascular Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
    Acta Chir Belg 106:361-6. 2006
    ..In high-risk patients, it is strongly advised to administer beta-blockers with heart rate determined dose adjustment, while the effects of preoperative revascularization remain subject to debate...
  41. ncbi request reprint Biphasic response to dobutamine predicts improvement of global left ventricular function after surgical revascularization in patients with stable coronary artery disease: implications of time course of recovery on diagnostic accuracy
    J H Cornel
    Department of Cardiology, Medical Center Alkmaar, The Netherlands
    J Am Coll Cardiol 31:1002-10. 1998
    ....
  42. ncbi request reprint The influence of aging on the prognostic value of the revised cardiac risk index for postoperative cardiac complications in vascular surgery patients
    G M J M Welten
    Department of Vascular Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur J Vasc Endovasc Surg 34:632-8. 2007
    ..However, age is not included as a risk factor. The aim was to assess the value of the Lee-index in vascular surgery patients among different age categories...
  43. pmc Long term prognostic value of myocardial viability and ischaemia during dobutamine stress echocardiography in patients with ischaemic cardiomyopathy undergoing coronary revascularisation
    V Rizzello
    Department of Cardiology, Thoraxcentre, Erasmus MC, The Netherlands
    Heart 92:239-44. 2006
    ..To evaluate the relative merits of viability and ischaemia for prognosis after revascularisation...
  44. ncbi request reprint Repetitive dobutamine stress echocardiography for the prediction of anthracycline cardiotoxicity
    M Bountioukos
    Thoraxcenter, Department of Cardiology, Erasmus MC, Dr Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands
    Eur J Echocardiogr 4:300-5. 2003
    ..To evaluate whether repetitive assessment of systolic and diastolic cardiac function by dobutamine stress echocardiography (DSE) can predict anthracycline cardiotoxicity...
  45. pmc Prognostic value of dobutamine stress echocardiography in patients with previous coronary revascularisation
    M Bountioukos
    Thoraxcentre, Department of Cardiology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Heart 90:1031-5. 2004
    ..To assess the prognostic value of dobutamine stress echocardiography (DSE) in patients with previous myocardial revascularisation...
  46. doi request reprint The prognostic value of impaired walking distance on long-term outcome in patients with known or suspected peripheral arterial disease
    I I de Liefde
    Department of Anesthesiology, Erasmus MC, Rotterdam, The Netherlands
    Eur J Vasc Endovasc Surg 38:482-7. 2009
    ..To assess the predictive value of walking distance after an exercise test on long-term outcome in patients with normal and impaired ankle-brachial index (ABI)...
  47. ncbi request reprint Prognosis of patients with peripheral arterial disease
    G M J M Welten
    Department of Vascular Surgery, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Cardiovasc Surg (Torino) 50:109-21. 2009
    ..Unfortunately, substantial differences in risk factor management and treatment and long-term outcome have been reported between PAD and CAD patients...
  48. ncbi request reprint Relation among exercise-induced ventricular arrhythmias, myocardial ischemia, and viability late after acute myocardial infarction
    A Elhendy
    Thoraxcenter, University Hospital Dijkzigt, Rotterdam, The Netherlands
    Am J Cardiol 86:723-9. 2000
    ..Myocardial ischemia in the dyssynergic myocardium appears to be a major mechanism underlying the occurrence of VA in these patients...
  49. pmc Assessing right ventricular function: the role of echocardiography and complementary technologies
    G B Bleeker
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Heart 92:i19-26. 2006
  50. doi request reprint Plaque type and composition as evaluated non-invasively by MSCT angiography and invasively by VH IVUS in relation to the degree of stenosis
    J E van Velzen
    Department of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands
    Heart 95:1990-6. 2009
    ..However, the relation between plaque composition and severity of stenosis remains largely unknown...
  51. ncbi request reprint Long-term prognostic value of dobutamine stress echocardiography in patients with atrial fibrillation
    D Poldermans
    Erasmus Medical Centre, Rotterdam, The Netherlands
    Chest 119:144-9. 2001
    ..To assess the long-term prognostic value of dobutamine stress echocardiography (DSE) for cardiac events (cardiac death, myocardial infarction, and late revascularization) in patients with atrial fibrillation (AF)...
  52. ncbi request reprint Long-term prognostic value of dobutamine-atropine stress echocardiography in 1737 patients with known or suspected coronary artery disease: A single-center experience
    D Poldermans
    Erasmus University, Rotterdam, The Netherlands
    Circulation 99:757-62. 1999
    ..The purpose of this study was to assess the long-term value of dobutamine-atropine stress echocardiography (DSE) for prediction of late cardiac events in patients with proven or suspected coronary artery disease...
  53. ncbi request reprint Diagnostic and prognostic value of non-invasive imaging in known or suspected coronary artery disease
    J D Schuijf
    Deparment of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Eur J Nucl Med Mol Imaging 33:93-104. 2006
    ..The aim of this review is to provide an overview of the available non-invasive imaging modalities and their merits for the diagnostic and prognostic work-up in patients with suspected or known CAD...
  54. ncbi request reprint Assessment of myocardial viability by nuclear imaging techniques
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Curr Cardiol Rep 7:124-9. 2005
    ..In contrast, patients without viable myocardium do not benefit and should be treated conservatively. Various nuclear imaging techniques are available...
  55. doi request reprint Short-term overt hypothyroidism induces discrete diastolic dysfunction in patients treated for differentiated thyroid carcinoma
    H C Hoftijzer
    Leiden University Medical Center, Leiden, The Netherlands
    Eur J Clin Invest 39:204-10. 2009
    ..Our objective was to investigate the effects of acute hypothyroidism on cardiac function in patients with iatrogenically induced subclinical hyperthyroidism after treatment for differentiated thyroid carcinoma...
  56. doi request reprint Impaired glucose regulation, elevated glycated haemoglobin and cardiac ischaemic events in vascular surgery patients
    H H H Feringa
    Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands
    Diabet Med 25:314-9. 2008
    ..This study investigated whether impaired glucose regulation and elevated glycated haemoglobin (HbA(1c)) levels are associated with increased cardiac ischaemic events in vascular surgery patients...
  57. ncbi request reprint Myocardial damage in high-risk patients undergoing elective endovascular or open infrarenal abdominal aortic aneurysm repair
    O Schouten
    Department of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands
    Eur J Vasc Endovasc Surg 33:544-9. 2007
    ..Therefore we compared cardiac outcome in patients at high-cardiac risk undergoing open or endovascular repair of infrarenal AAA using preoperative DSE results...
  58. ncbi request reprint Assessment of left ventricular volumes and ejection fraction with 16-slice multi-slice computed tomography; comparison with 2D-echocardiography
    J D Schuijf
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Int J Cardiol 116:201-5. 2007
    ..Accordingly, the purpose of the present study was to validate assessment of LV function with MSCT using 2D-echocardiography in a large cohort of patients...
  59. ncbi request reprint Differences in plaque composition and distribution in stable coronary artery disease versus acute coronary syndromes; non-invasive evaluation with multi-slice computed tomography
    J D Schuijf
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Acute Card Care 9:48-53. 2007
    ..The purpose of the study was to compare plaque composition and distribution with multi-slice computed tomography (MSCT) between patients presenting with either stable coronary artery disease (CAD) or ACS...
  60. pmc Long term outcome in patients with silent versus symptomatic ischaemia during dobutamine stress echocardiography
    E Biagini
    Department of Cardiology, Thoraxcentre, Erasmus MC, Rotterdam, The Netherlands
    Heart 91:737-42. 2005
    ..To compare the long term prognosis of patients having silent versus symptomatic ischaemia during dobutamine stress echocardiography (DSE)...
  61. ncbi request reprint Nuclear imaging is more sensitive for the detection of viable myocardium than dobutamine echocardiography
    G W Sloof
    Department of Nuclear Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Nucl Med Commun 24:375-81. 2003
    ..The substantial number of segments with preserved glucose and fatty acid utilization but without contractile reserve, suggests an underestimation of myocardial viability by dobutamine echocardiography...
  62. ncbi request reprint Bisoprolol reduces cardiac death and myocardial infarction in high-risk patients as long as 2 years after successful major vascular surgery
    D Poldermans
    Erasmus Medical Center, Rotterdam, The Netherlands
    Eur Heart J 22:1353-8. 2001
    ..30 (0.11-0.83). CONCLUSIONS: Bisoprolol significantly reduced long-term cardiac death and myocardial infarction in high-risk patients after successful major cardiac vascular surgery...
  63. ncbi request reprint Evaluation of left ventricular function and volumes in patients with ischaemic cardiomyopathy: gated single-photon emission computed tomography versus two-dimensional echocardiography
    E C Vourvouri
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Eur J Nucl Med 28:1610-5. 2001
    ....
  64. ncbi request reprint Noninvasive evaluation of ischaemic heart disease: myocardial perfusion imaging or stress echocardiography?
    A F L Schinkel
    Thoraxcenter, Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands
    Eur Heart J 24:789-800. 2003
  65. ncbi request reprint Cardiac risk and perioperative management
    M D Kertai
    Department of Cardiology, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Cardiovasc Surg (Torino) 44:431-5. 2003
    ..Careful preoperative evaluation of CAD and perioperative management with beta-blockers and statins may offer the physician a unique opportunity to improve patients' perioperative and long-term outcome...
  66. pmc Quantification of regional left ventricular function in Q wave and non-Q wave dysfunctional regions by tissue Doppler imaging in patients with ischaemic cardiomyopathy
    M Bountioukos
    Thoraxcentre, Department of Cardiology, Erasmus Medical Centre, Rotterdam, Netherlands
    Heart 89:1322-6. 2003
    ..To quantify regional left ventricular (LV) function and contractile reserve in Q wave and non-Q wave regions in patients with previous myocardial infarction...
  67. ncbi request reprint Why do patients with ischemic cardiomyopathy and a substantial amount of viable myocardium not always recover in function after revascularization?
    Arend F L Schinkel
    Thoraxcenter, Erasus Medical Center, Rotterdam, The Netherlands
    J Thorac Cardiovasc Surg 127:385-90. 2004
    ..The aim of this study was to evaluate why not all patients with a substantial amount of viable tissue recover in function after revascularization...
  68. ncbi request reprint Effect of diabetes mellitus on myocardial 18F-FDG SPECT using acipimox for the assessment of myocardial viability
    Arend F L Schinkel
    Thoraxcenter, Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Nucl Med 44:877-83. 2003
    ..The aim of this study was to compare the feasibility and image quality of cardiac (18)F-FDG SPECT imaging using acipimox in patients with diabetes and patients without diabetes...
  69. ncbi request reprint Assessment of myocardial viability in ischemic cardiomyopathy
    Jeroen J Bax
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Heart Lung Circ 14:S8-13. 2005
    ..Moreover, the value of these techniques for the prediction of not only improvement of function, but also improvement in exercise capacity, reverse LV remodeling, and long-term prognosis, is discussed...
  70. ncbi request reprint Accuracy of PET in predicting functional recovery after revascularisation in patients with chronic ischaemic dysfunction: head-to-head comparison between blood flow, glucose utilisation and water-perfusable tissue fraction
    Jeroen J Bax
    Leiden University Medical Center, The Netherlands
    Eur J Nucl Med Mol Imaging 29:721-7. 2002
    ..It is concluded that metabolic imaging is superior to perfusion-based indexes for assessment of the potential for functional recovery after revascularisation...
  71. ncbi request reprint Feasibility and image quality of dual-isotope SPECT using 18F-FDG and (99m)Tc-tetrofosmin after acipimox administration
    Boen L R Kam
    Department of Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands
    J Nucl Med 44:140-5. 2003
    ..Recently, the use of a nicotinic acid derivative, acipimox, has been suggested, but limited data are available on the image quality of the (18)F-FDG studies using this approach...
  72. doi request reprint Prediction of cardiac resynchronization therapy response: value of calibrated integrated backscatter imaging
    Matteo Bertini
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Circ Cardiovasc Imaging 3:86-93. 2010
    ....
  73. ncbi request reprint QT dispersion correlates to myocardial viability assessed by dobutamine stress echocardiography in patients with severely depressed left ventricular function due to coronary artery disease
    Manolis Bountioukos
    Thoraxcenter, Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur J Heart Fail 6:187-93. 2004
    ..QT dispersion is prolonged in numerous cardiac diseases, representing a general repolarization abnormality...
  74. ncbi request reprint Predicting perioperative cardiac risk
    Miklos D Kertai
    Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Prog Cardiovasc Dis 47:240-57. 2005
    ..beta-Blockers should be prescribed to all patients, and coronary revascularization should be reserved for high-risk patients who have a clearly defined need for revascularization independent of the need for major vascular surgery...
  75. ncbi request reprint Assessment of viable tissue in Q-wave regions by metabolic imaging using single-photon emission computed tomography in ischemic cardiomyopathy
    Arend F L Schinkel
    Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Cardiol 89:1171-5. 2002
    ..Residual viable tissue persists in a high proportion of dysfunctional ventricular regions according to FDG SPECT metabolic imaging...
  76. ncbi request reprint Impact of diabetes mellitus on prediction of clinical outcome after coronary revascularization by 18F-FDG SPECT in patients with ischemic left ventricular dysfunction
    Arend F L Schinkel
    Thoraxcenter, Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Nucl Med 47:68-73. 2006
    ....
  77. ncbi request reprint Plasma natriuretic peptide levels reflect changes in heart failure symptoms, left ventricular size and function after surgical mitral valve repair
    Harm H H Feringa
    Department of Cardiothoracic Surgery Cardiology, C 5, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands
    Int J Cardiovasc Imaging 23:159-65. 2007
    ....
  78. ncbi request reprint Individual prediction of functional recovery after coronary revascularization in patients with ischemic cardiomyopathy: the scar-to-biphasic model
    Vittoria Rizzello
    Department of Cardiology, Thoraxcenter, Erasmus MC, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Am J Cardiol 91:1406-9. 2003
    ..In patients with ischemic cardiomyopathy and a mixture of viable and nonviable tissue, both numbers of viable and nonviable segments should be considered to accurately predict functional recovery after revascularization...
  79. pmc The heart in sporadic inclusion body myositis: a study in 51 patients
    Fieke M Cox
    Department of Neurology, Leiden University Medical Centre, P O Box 9600, 2300 RC, Leiden, The Netherlands
    J Neurol 257:447-51. 2010
    ..The prevalence of cardiac abnormalities in sIBM does not seem to be higher than would be expected in these elderly patients. Elevated CK-MB and cTnT levels are common, in contrast to cTnI, but do not reflect cardiac pathology...
  80. ncbi request reprint Relation between QT dispersion and myocardial viability in ischemic cardiomyopathy
    Arend F L Schinkel
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
    Am J Cardiol 92:712-5. 2003
    ..Patients with a low QT dispersion had a substantial amount of viable myocardium, whereas patients with a high QT dispersion had predominantly nonviable scar tissue...
  81. ncbi request reprint Left ventricular dyssynchrony in patients with heart failure: pathophysiology, diagnosis and treatment
    Gabe B Bleeker
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Nat Clin Pract Cardiovasc Med 3:213-9. 2006
    ..In this review, we discuss the pathophysiology, diagnosis and treatment of LV dyssynchrony in patients with heart failure...
  82. ncbi request reprint Dobutamine-induced contractile reserve in stunned, hibernating, and scarred myocardium in patients with ischemic cardiomyopathy
    Arend F L Schinkel
    Thoraxcenter, Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Nucl Med 44:127-33. 2003
    ..The aim of this study was to assess the presence of contractile reserve in response to dobutamine infusion in a large group of patients with stunned and hibernating myocardium...
  83. doi request reprint Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus
    Luuk J Rijzewijk
    Department of Endocrinology, VU University Medical Center, Amsterdam, The Netherlands
    J Am Coll Cardiol 52:1793-9. 2008
    ....
  84. ncbi request reprint Value of myocardial viability estimation using dobutamine stress echocardiography in assessing risk preoperatively before noncardiac vascular surgery in patients with left ventricular ejection fraction <35%
    Stefanos E Karagiannis
    Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands
    Am J Cardiol 99:1555-9. 2007
    ..Sustained improvement was associated with improved survival. In conclusion, DSE provides accurate risk stratification of patients with HF undergoing vascular surgery...
  85. ncbi request reprint Prognostic significance of akinesis becoming dyskinesis during dobutamine stress echocardiography
    Fabiola B Sozzi
    Thoraxcentre, Erasmus Medical Centre, Rotterdam, The Netherlands
    J Am Soc Echocardiogr 20:257-61. 2007
    ..Akinesis becoming dyskinesis (AKBD) at high-dose dobutamine stress echocardiography (DSE) has been disregarded as a marker of myocardial ischemia. However, its prognostic significance is unknown...
  86. ncbi request reprint Non-invasive diagnosis of in stent stenosis by stress 99m technetium tetrofosmin myocardial perfusion imaging
    Abdou Elhendy
    Thoraxcenter, University Hospital Rotterdam, Rotterdam, The Netherlands
    Int J Cardiovasc Imaging 22:657-62. 2006
    ..The aim of this study was to assess the accuracy of stress 99m technetium tetrofosmin myocardial perfusion imaging for the diagnosis of in stent stenosis (ISS)...
  87. ncbi request reprint Usefulness of intramyocardial injection of autologous bone marrow-derived mononuclear cells in patients with severe angina pectoris and stress-induced myocardial ischemia
    Saskia L M A Beeres
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Am J Cardiol 97:1326-31. 2006
    ..1 +/- 3.2 to 2.3 +/- 2.6 (p<0.01). In conclusion, autologous bone marrow-derived mononuclear cell injection in patients with ischemia is safe, reduces anginal symptoms, improves myocardial perfusion, and increases LV function...
  88. doi request reprint Viability assessment with global left ventricular longitudinal strain predicts recovery of left ventricular function after acute myocardial infarction
    Sjoerd A Mollema
    Department of Cardiology and the Department of Nuclear Medicine, Leiden University Medical Center, Albinusdreef 2, Leiden, The Netherlands
    Circ Cardiovasc Imaging 3:15-23. 2010
    ..In the current study, the role of global LV strain assessed with novel automated function imaging (AFI) to predict functional recovery after acute infarction was evaluated...
  89. doi request reprint Restrictive mitral annuloplasty cures ischemic mitral regurgitation and heart failure
    Jerry Braun
    Department of Cardiothoracic Surgery, Leids Universitair Medisch Centrum, Leiden, The Netherlands
    Ann Thorac Surg 85:430-6; discussion 436-7. 2008
    ..We report late outcome in relation to preoperative left ventricular end-diastolic diameter (LVEDD) cutoff values, previously identified to predict intermediate-term left ventricular reverse remodeling...
  90. ncbi request reprint Assessment of myocardial viability in patients with heart failure
    Arend F L Schinkel
    Thoraxcenter, Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    J Nucl Med 48:1135-46. 2007
    ....
  91. ncbi request reprint Usefulness of QRS duration to predict response to cardiac resynchronization therapy in patients with end-stage heart failure
    Sjoerd A Mollema
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Am J Cardiol 100:1665-70. 2007
    ..In conclusion, baseline QRS duration is not predictive for clinical and echocardiographic responses to CRT at 6-month follow-up. Better predictors for CRT response are needed...
  92. doi request reprint Biventricular pacing-induced acute response in baroreflex sensitivity has predictive value for midterm response to cardiac resynchronization therapy
    Maaike G J Gademan
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Am J Physiol Heart Circ Physiol 297:H233-7. 2009
    ..Our study demonstrates that a CRT-induced acute BRS increase has predictive value for the echocardiographic response to CRT. This finding suggests that the autonomic nervous system is actively involved in CRT-related reverse remodeling...
  93. ncbi request reprint Role of imaging in cardiac stem cell therapy
    Saskia L M A Beeres
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 49:1137-48. 2007
    ..In addition, a comprehensive summary is provided of the currently available studies investigating a cell therapy-related effect on left ventricular function, myocardial perfusion, scar tissue, and myocardial viability...
  94. ncbi request reprint Relative merits of M-mode echocardiography and tissue Doppler imaging for prediction of response to cardiac resynchronization therapy in patients with heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    Gabe B Bleeker
    Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
    Am J Cardiol 99:68-74. 2007
    ..05) when color-coded TDI was used. Color-coded TDI was superior to M-mode echocardiography for prediction of response to CRT...
  95. ncbi request reprint Noninvasive evaluation of coronary sinus anatomy and its relation to the mitral valve annulus: implications for percutaneous mitral annuloplasty
    Laurens F Tops
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Circulation 115:1426-32. 2007
    ..The feasibility of evaluating these issues noninvasively with multislice computed tomography was determined...
  96. ncbi request reprint Diastolic dysfunction is associated with altered myocardial metabolism in asymptomatic normotensive patients with well-controlled type 2 diabetes mellitus
    Michaela Diamant
    Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Coll Cardiol 42:328-35. 2003
    ..This study evaluated myocardial function in relation to high-energy phosphate (HEP) metabolism in asymptomatic patients with uncomplicated type 2 diabetes mellitus using magnetic resonance (MR) techniques...
  97. ncbi request reprint Evaluation of the Quantitative Gated SPECT (QGS) software program in the presence of large perfusion defects
    Yves G C J America
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2300, RC Leiden, The Netherlands
    Int J Cardiovasc Imaging 21:519-29. 2005
    ..To evaluate the reproducibility and operator dependence for the quantitative regional left ventricular functional parameters (LVFP) assessed by Cedars-Sinai's Quantitative automated gated SPECT (QGS) software...
  98. ncbi request reprint Incidence of recovery of contractile function following revascularization in patients with ischemic left ventricular dysfunction
    Arend F L Schinkel
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Cardiol 93:14-7. 2004
    ..Improvement of LVEF after revascularization was frequently observed in patients with a more severely impaired baseline LVEF. At least 3 segments with improvement of function were needed for an improvement of LVEF of >/=5%...
  99. ncbi request reprint Preoperative left ventricular dimensions predict reverse remodeling following restrictive mitral annuloplasty in ischemic mitral regurgitation
    Jerry Braun
    Department of Cardiothoracic Surgery, Leiden University Medical Center, Albinusdreef 1, 2333 AL Leiden, The Netherlands
    Eur J Cardiothorac Surg 27:847-53. 2005
    ..In this study, the extent of reverse remodeling of the left ventricle following this strategy is assessed, as well as the factors that influence it...
  100. ncbi request reprint Impact of viability, ischemia, scar tissue, and revascularization on outcome after aborted sudden death
    Alida E Borger van der Burg
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands
    Circulation 108:1954-9. 2003
    ....
  101. ncbi request reprint Cardiac multidetector-row computed tomography in patients with unstable angina
    Martijn S Dirksen
    Department of Radiology, Leiden University Medical Center, The Netherlands
    Am J Cardiol 95:457-61. 2005
    ..High accuracies in excluding significant coronary artery disease and in confirming normal LV function were observed, suggesting potential clinical use for screening of patients who present with symptoms of unstable angina...