Research Topics
| L M BallSummaryAffiliation: Leiden University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Significance of amplified fragment length polymorphism in identification and epidemiological examination of Candida species colonization in children undergoing allogeneic stem cell transplantationL M Ball
Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands
J Clin Microbiol 42:1673-9. 2004..albicans by a rapid enzyme test. AFLP analysis of surveillance cultures allowed more accurate and informative epidemiological evaluations of pathogenic yeasts in children during transplantation...
Graft dysfunction and delayed immune reconstitution following haploidentical peripheral blood hematopoietic stem cell transplantationL M Ball
Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands
Bone Marrow Transplant 35:S35-8. 2005..We are investigating new strategies to improve the outcome of haplo-identical PBSCT, which may allow us to offer this form of treatment to more children requiring urgent HSCT...
Potential role of mesenchymal stromal cells in pediatric hematopoietic SCTL M Ball
Department of Paediatric Immunology, Hematology, Oncology, Bone Marrow Transplantation, and Auto immune Diseases, Leiden University Medical Center, Leiden, The Netherlands
Bone Marrow Transplant 42:S60-6. 2008..Currently, much needed randomized studies under the auspices of the EBMT are ongoing to determine the optimal use of these exciting new modalities of treatment...- Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantationLynne M Ball
Department of Pediatric Stem Cell Transplantation, Leiden University Medical Centre, Leiden, The Netherlands
Blood 110:2764-7. 2007..These data suggest that MSCs, possibly thanks to their potent immunosuppressive effect on alloreactive host T lymphocytes escaping the preparative regimen, reduce the risk of graft failure in haploidentical HSC transplant recipients... - Acute GvHD: pathogenesis and classificationL M Ball
Department of Paediatric Immunology, Hematology, Oncology, Bone Marrow Transplantation, and Auto immune Diseases, Leiden University Medical Center, Leiden, The Netherlands
Bone Marrow Transplant 41:S58-64. 2008..The authors concentrate on the most recent knowledge of the pathogenesis as well as the classification of aGvHD... - Allogeneic bone marrow transplantation for juvenile myelomonocytic leukemia: a single center experience of 23 patientsE T Korthof
Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands
Bone Marrow Transplant 35:455-61. 2005..9). Together with a trend towards less relapse in patients with graft-versus-host-disease and in patients transplanted with matched unrelated donors, this suggests a graft-versus-leukemia effect of allogeneic BMT in JMML... - ABO incompatible stem cell transplantation in children does not influence outcomeA M Helming
Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands
Pediatr Blood Cancer 49:313-7. 2007.... - Paediatric allogeneic bone marrow transplantation for homozygous beta-thalassaemia, the Dutch experienceL M Ball
The Department of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands
Bone Marrow Transplant 31:1081-7. 2003..Our results emphasise the importance of the conditioning regimen and post-transplant chimerism surveillance predictive of rejection or long-term stable engraftment... - Intravenous busulfan in children prior to stem cell transplantation: study of pharmacokinetics in association with early clinical outcome and toxicityJ Zwaveling
Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands
Bone Marrow Transplant 35:17-23. 2005..We concluded that, in accordance with previous data, within the observed AUCs no clear relationship was observed between Bu AUC and outcome with respect to toxicity, engraftment and relapse... - Immediate and long-term somatic effects, and health-related quality of life of BM donation during early childhood. A single-center report in 210 pediatric donorsS M van Walraven
Department of Pediatric SCT, Leiden University Medical Centre, Leiden, The Netherlands
Bone Marrow Transplant 48:40-5. 2013..These results indicate the need for development of (inter)national guidelines for pediatric stem cell donor care management... - Managing a dual role--experiences and coping strategies of parents donating haploidentical G-CSF mobilized peripheral blood stem cells to their childrenS M van Walraven
Department of Pediatrics, Leiden University Medical Centre, Leiden, The Netherlands
Psychooncology 21:168-75. 2012..Hematopoietic stem cell transplantation is an effective therapy for life-threatening hematological diseases. Parents may be asked to donate hematopoietic stem cells for their child when no compatible related or unrelated donor is available... - High burden of late effects after haematopoietic stem cell transplantation in childhood: a single-centre studyD Bresters
Department of Paediatric Immunology, Haemato oncology, Bone Marrow Transplantation and Auto immune Diseases, Leiden University Medical Centre, Leiden, The Netherlands
Bone Marrow Transplant 45:79-85. 2010..001) and a conditioning regimen including irradiation OR 2.2, 95% CI 1.1-4.7, P=0.03). In conclusion, a high burden of late effects is found in childhood HSCT survivors after a median follow-up of only 7 years... - Reconciling animal and human data in a cancer risk assessment of acrylonitrileM R Schulz
Department of Epidemiology University of North Carolina at Chapel Hill, 27599-7400, USA
Scand J Work Environ Health 27:14-20. 2001..The lack of observed excess in CNS cancer among the studied workers may have been due to low exposures, insufficient follow-up times, or both...