Ralph W Kupka

Summary

Country: The Netherlands

Publications

  1. ncbi request reprint Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients
    Ralph W Kupka
    Altrecht Institute for Mental Health Care, Tolsteegsingel 2A, 3582 AC Utrecht, Netherlands
    Am J Psychiatry 162:1273-80. 2005
  2. ncbi request reprint Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder
    Ralph W Kupka
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    Bipolar Disord 9:531-5. 2007
  3. ncbi request reprint Rapid and non-rapid cycling bipolar disorder: a meta-analysis of clinical studies
    Ralph W Kupka
    Altrecht Institute for Mental Health Care and University Medical Center Utrecht, Utrecht, The Netherlands
    J Clin Psychiatry 64:1483-94. 2003
  4. ncbi request reprint Correlates of 1-year prospective outcome in bipolar disorder: results from the Stanley Foundation Bipolar Network
    Willem A Nolen
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    Am J Psychiatry 161:1447-54. 2004
  5. doi request reprint Comorbidity of anxiety and depressive disorders: a comparative population study in Western and non-Western inhabitants in the Netherlands
    Agnes C Schrier
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    Int J Soc Psychiatry 58:186-94. 2012
  6. doi request reprint Similar associations between personality dimensions and anxiety or depressive disorders in a population study of Turkish-Dutch, Moroccan-Dutch, and native Dutch subjects
    Agnes C Schrier
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    J Nerv Ment Dis 201:421-8. 2013
  7. pmc Treatment of bipolar disorder in the Netherlands and concordance with treatment guidelines: study protocol of an observational, longitudinal study on naturalistic treatment of bipolar disorder in everyday clinical practice
    Joannes W Renes
    Altrecht Institute for Mental Health Care, Lange Nieuwstraat 119, 3512 PG Utrecht, The Netherlands
    BMC Psychiatry 14:58. 2014
  8. doi request reprint Similarity in depressive symptom profile in a population-based study of migrants in the Netherlands
    Agnes C Schrier
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 45:941-51. 2010
  9. doi request reprint The effectiveness of restarted lithium treatment after discontinuation: reviewing the evidence for discontinuation-induced refractoriness
    Christine de Vries
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    Bipolar Disord 15:645-9. 2013
  10. ncbi request reprint An imbalance in the production of IL-1beta and IL-6 by monocytes of bipolar patients: restoration by lithium treatment
    Esther M Knijff
    Department of Immunology, Erasmus MC, Rotterdam, The Netherlands
    Bipolar Disord 9:743-53. 2007

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients
    Ralph W Kupka
    Altrecht Institute for Mental Health Care, Tolsteegsingel 2A, 3582 AC Utrecht, Netherlands
    Am J Psychiatry 162:1273-80. 2005
    ..To detect risk factors for rapid cycling in bipolar disorder, the authors compared characteristics of rapid-cycling and non-rapid-cycling patients both from a categorical and a dimensional perspective...
  2. ncbi request reprint Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder
    Ralph W Kupka
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    Bipolar Disord 9:531-5. 2007
    ..To assess the proportion of time spent in mania, depression and euthymia in a large cohort of bipolar subjects studied longitudinally, and to investigate depression/mania ratios in patients with bipolar I versus bipolar II disorder...
  3. ncbi request reprint Rapid and non-rapid cycling bipolar disorder: a meta-analysis of clinical studies
    Ralph W Kupka
    Altrecht Institute for Mental Health Care and University Medical Center Utrecht, Utrecht, The Netherlands
    J Clin Psychiatry 64:1483-94. 2003
    ..Several risk factors have been suggested to be associated with rapid cycling. The purpose of this meta-analysis was to compare clinical studies for the evidence of discriminating factors between rapid and non-rapid cycling...
  4. ncbi request reprint Correlates of 1-year prospective outcome in bipolar disorder: results from the Stanley Foundation Bipolar Network
    Willem A Nolen
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    Am J Psychiatry 161:1447-54. 2004
    ..The purpose of the study was to examine potential correlates of outcome in patients treated for bipolar disorder...
  5. doi request reprint Comorbidity of anxiety and depressive disorders: a comparative population study in Western and non-Western inhabitants in the Netherlands
    Agnes C Schrier
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    Int J Soc Psychiatry 58:186-94. 2012
    ..Overlap of depressive and anxiety symptoms is supposedly more common in non-Western populations. This can lead to diagnostic uncertainity and undertreatment...
  6. doi request reprint Similar associations between personality dimensions and anxiety or depressive disorders in a population study of Turkish-Dutch, Moroccan-Dutch, and native Dutch subjects
    Agnes C Schrier
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    J Nerv Ment Dis 201:421-8. 2013
    ....
  7. pmc Treatment of bipolar disorder in the Netherlands and concordance with treatment guidelines: study protocol of an observational, longitudinal study on naturalistic treatment of bipolar disorder in everyday clinical practice
    Joannes W Renes
    Altrecht Institute for Mental Health Care, Lange Nieuwstraat 119, 3512 PG Utrecht, The Netherlands
    BMC Psychiatry 14:58. 2014
    ....
  8. doi request reprint Similarity in depressive symptom profile in a population-based study of migrants in the Netherlands
    Agnes C Schrier
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    Soc Psychiatry Psychiatr Epidemiol 45:941-51. 2010
    ..Our second aim was to study ethnic differences in the association of depressive symptoms and general functioning...
  9. doi request reprint The effectiveness of restarted lithium treatment after discontinuation: reviewing the evidence for discontinuation-induced refractoriness
    Christine de Vries
    Altrecht Institute for Mental Health Care, Utrecht, The Netherlands
    Bipolar Disord 15:645-9. 2013
    ..We sought to determine whether the risk of relapse in patients with bipolar disorder is higher after discontinuation and restart of lithium treatment as compared to continuous lithium treatment in these same patients...
  10. ncbi request reprint An imbalance in the production of IL-1beta and IL-6 by monocytes of bipolar patients: restoration by lithium treatment
    Esther M Knijff
    Department of Immunology, Erasmus MC, Rotterdam, The Netherlands
    Bipolar Disord 9:743-53. 2007
    ..To study the ex vivo interleukin (IL)-1beta and IL-6 production of monocytes in bipolar disorder (BD) patients in the absence/presence of lithium...
  11. ncbi request reprint Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: results of a large, multisite study
    Lori L Altshuler
    Department of Psychiatry, VA Greater Los Angeles Healthcare System, West Los Angeles Healthcare Center, CA, USA
    J Clin Psychiatry 67:1551-60. 2006
    ..Research examining this relationship in persons with bipolar disorder is rare. This study sought to evaluate the association between subsyndromal depressive symptoms and role functioning in subjects with bipolar disorder...
  12. ncbi request reprint Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon
    Trisha Suppes
    Bipolar Disorder Research Program, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas 75390 9121, USA
    Arch Gen Psychiatry 62:1089-96. 2005
    ..The prevalence of depressive symptoms co-occurring with hypomanic symptoms has not been quantified. Whether there is a greater likelihood for women to experience mixed symptoms has not been resolved...
  13. ncbi request reprint Open-label adjunctive zonisamide in the treatment of bipolar disorders: a prospective trial
    Susan L McElroy
    Psychopharmacology Research Program, Department of Psychiatry, PO Box 670559, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    J Clin Psychiatry 66:617-24. 2005
    ..The response of 62 outpatients with DSM-IV bipolar disorders to open-label adjunctive zonisamide was evaluated in a prospective 8-week acute trial, followed by a 48-week continuation trial, conducted from June 2001 through May 2002...
  14. ncbi request reprint Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood stabilizers
    Gabriele S Leverich
    Biological Psychiatry Branch, National Institutes of Mental Health, Bldg 10 Room 3S239, 10 Center Drive, MSC 1272, Bethesda, MD 20892 1272, USA
    Am J Psychiatry 163:232-9. 2006
    ..The authors examined the comparative risks of switches in mood polarity into hypomania or mania during acute and continuation trials of adjunctive antidepressant treatment of bipolar depression...
  15. ncbi request reprint High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder
    M Nadine Breunis
    Department of Immunology, Erasmus University Rotterdam MNB, HAD, Rotterdam, The Netherlands
    Biol Psychiatry 53:157-65. 2003
    ..In the present study, we investigated other signs of immune activation in bipolar patients, in particular an activation of the T cell system...
  16. ncbi request reprint A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network
    Robert M Post
    Department of Health and Human Services, National Institutes of Health, National Institute of Mental Health, Biological Psychiatry Branch, Bethesda, MD 20892 1272, USA
    Bipolar Disord 5:396-406. 2003
    ..This paper reviews new data on: (1) depression in bipolar illness, (2) switch rates on ADs and (3) risks of AD discontinuation that are pertinent to the ongoing discussion and recommendations...
  17. ncbi request reprint A high prevalence of organ-specific autoimmunity in patients with bipolar disorder
    Roos C Padmos
    Department of Immunology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Biol Psychiatry 56:476-82. 2004
    ..Here we report the prevalence of other organ-specific autoantibodies: H/K adenosine triphosphatase (ATPA), glutamic acid decarboxylase-65 (GAD65A), and GAD-67 (GAD67A)...
  18. doi request reprint A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes
    Roos C Padmos
    Department of Immunology, Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands
    Arch Gen Psychiatry 65:395-407. 2008
    ..Mood disturbances are associated with an activated inflammatory response system...
  19. doi request reprint Are bipolar mood symptoms affected by the phase of the menstrual cycle?
    Geetha Shivakumar
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9086, USA
    J Womens Health (Larchmt) 17:473-8. 2008
    ..We sought to examine the relationship between bipolar disorder and menstrual cycle-related mood changes. To our knowledge, this is one of the largest samples in the literature addressing this issue...
  20. ncbi request reprint Evidence that the immunopathogenic mechanism of lithium-induced psoriasis differs from that of regular psoriasis
    Esther M Knijff
    Bipolar Disord 7:388-9. 2005
  21. ncbi request reprint Quetiapine for the continuation treatment of bipolar depression: naturalistic prospective case series from the Stanley Bipolar Treatment Network
    Trisha Suppes
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9121, USA
    Int Clin Psychopharmacol 22:376-81. 2007
    ..No between-group differences in improvement were found. Adjunctive quetiapine may be useful as continuation treatment in bipolar populations with both pure depressive and cycling symptoms. Further controlled studies are warranted...
  22. ncbi request reprint Monocyte-derived dendritic cells in bipolar disorder
    Esther M Knijff
    Department of Immunology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Biol Psychiatry 59:317-26. 2006
    ..Dendritic cells (DC) are key regulators of the immune system, which is compromised in patients with bipolar disorder. We sought to study monocyte-derived DC in bipolar disorder...
  23. ncbi request reprint The poor prognosis of childhood-onset bipolar disorder
    Gabriele S Leverich
    Department of Health and Human Services, National Institutes of Health, National Institute of Mental Health, Biological Psychiatry Branch, Bethesda, MD 20892 1272, USA
    J Pediatr 150:485-90. 2007
    ..We examined age of onset of bipolar disorder as a potential course-of-illness modifier with the hypothesis that early onset will engender more severe illness...
  24. ncbi request reprint A relative resistance of T cells to dexamethasone in bipolar disorder
    Esther M Knijff
    Department of Immunology, Erasmus MC, 3000 DR Rotterdam, The Netherlands
    Bipolar Disord 8:740-50. 2006
    ..In this study, we investigated the in vitro responsiveness of T cells to dexamethasone (DEX) of patients with bipolar disorder (BD)...
  25. ncbi request reprint High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposure
    Ralph W Kupka
    Altrecht Centre for Mental Health Care and University Medical Centre Utrecht, Vrouwjuttenhof 18, 3512 PZ Utrecht, The Netherlands
    Biol Psychiatry 51:305-11. 2002
    ..We assessed the prevalence of thyroperoxidase antibodies (TPO-Abs) and thyroid failure in outpatients with bipolar disorder compared with two control groups...