J M Karczewski

Summary

Country: The Netherlands

Publications

  1. ncbi request reprint Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP-ribose) polymerase and Ca2+ chelation: involvement of a common mechanism
    J M Karczewski
    Department of Toxicology, University of Nijmegen, The Netherlands
    Biochem Pharmacol 57:19-26. 1999
  2. ncbi request reprint Quinone toxicity in DT-diaphorase-efficient and -deficient colon carcinoma cell lines
    J M Karczewski
    Department of Toxicology, University of Nijmegen, The Netherlands
    Biochem Pharmacol 57:27-37. 1999

Detail Information

Publications2

  1. ncbi request reprint Prevention of oxidant-induced cell death in Caco-2 colon carcinoma cells after inhibition of poly(ADP-ribose) polymerase and Ca2+ chelation: involvement of a common mechanism
    J M Karczewski
    Department of Toxicology, University of Nijmegen, The Netherlands
    Biochem Pharmacol 57:19-26. 1999
    ....
  2. ncbi request reprint Quinone toxicity in DT-diaphorase-efficient and -deficient colon carcinoma cell lines
    J M Karczewski
    Department of Toxicology, University of Nijmegen, The Netherlands
    Biochem Pharmacol 57:27-37. 1999
    ..We conclude that arylation is a major contributing factor in the toxicity of quinones. For this reason, NQ was the most toxic quinone, followed by MEN, and the pure redoxcycler DIM elicited modest toxicity in Caco-2 cells...