A M Osman

Summary

Affiliation: Institute for Inland Water Management and Waste Water Treatment
Country: The Netherlands

Publications

  1. ncbi Evidence for redox cycling of lawsone (2-hydroxy-1,4-naphthoquinone) in the presence of the hypoxanthine/xanthine oxidase system
    A M Osman
    Institute for Inland Water Management and Waste Water Treatment RIZA, PO Box 17, 8200 AA Lelystad, The Netherlands
    J Appl Toxicol 23:209-12. 2003
  2. ncbi Menadione enhances oxyradical formation in earthworm extracts: vulnerability of earthworms to quinone toxicity
    A M Osman
    Institute for Inland Water Management and Waste Water Treatment RIZA, P O Box 17, 8200 AA Lelystad, The Netherlands
    Aquat Toxicol 65:101-9. 2003
  3. ncbi Studies on the DT-diaphorase-catalysed reaction employing quinones as substrates: evidence for a covalent modification of DT-diaphorase by tetrachloro-p-benzoquinone
    Ahmed M Osman
    Institute for Inland Water Management and Waste Water Treatment, P O Box 17, 8200 AA Lelystad, The Netherlands
    Chem Biol Interact 147:99-108. 2004
  4. ncbi In vivo exposure of Dreissena polymorpha mussels to the quinones menadione and lawsone: menadione is more toxic to mussels than lawsone
    A M Osman
    Institute for Inland Water Management and Waste Water Treatment, PO Box 17, 8200 AA Lelystad, The Netherlands
    J Appl Toxicol 24:135-41. 2004
  5. ncbi Kinetic and stability studies on the chloroperoxidase complexes in presence of tert-butyl hydroperoxide
    Paolo Toti
    , Dipartimento di Fisiologia e Biochimica, , Via S. Zeno 51, 56027 Pisa, Italy
    Biophys Chem 113:105-13. 2005
  6. ncbi A linearization method for low catalytic activity enzyme kinetic analysis
    Paolo Toti
    Department of Physiology and Biochemistry, Biochemistry Unit, University of Pisa, Italy
    Biophys Chem 114:245-51. 2005

Collaborators

  • P J Den Besten
  • Paolo Toti
  • Carlo Bauer
  • Antonella Petri
  • Moreno Paolini
  • Valerio Pelaia
  • Tiziana Gambicorti

Detail Information

Publications6

  1. ncbi Evidence for redox cycling of lawsone (2-hydroxy-1,4-naphthoquinone) in the presence of the hypoxanthine/xanthine oxidase system
    A M Osman
    Institute for Inland Water Management and Waste Water Treatment RIZA, PO Box 17, 8200 AA Lelystad, The Netherlands
    J Appl Toxicol 23:209-12. 2003
    ..Such an observation therefore reconciles the in vivo toxicity results of this naphthoquinone with those of in vitro experiments...
  2. ncbi Menadione enhances oxyradical formation in earthworm extracts: vulnerability of earthworms to quinone toxicity
    A M Osman
    Institute for Inland Water Management and Waste Water Treatment RIZA, P O Box 17, 8200 AA Lelystad, The Netherlands
    Aquat Toxicol 65:101-9. 2003
    ..On the contrary, mussels have efficient DT-diaphorase, which catalyzes two-electron reduction of menadione directly to hydroquinone, thus circumventing the formation of semiquinone...
  3. ncbi Studies on the DT-diaphorase-catalysed reaction employing quinones as substrates: evidence for a covalent modification of DT-diaphorase by tetrachloro-p-benzoquinone
    Ahmed M Osman
    Institute for Inland Water Management and Waste Water Treatment, P O Box 17, 8200 AA Lelystad, The Netherlands
    Chem Biol Interact 147:99-108. 2004
    ..This indicates a covalent modification of the rat liver DT-diaphorase by tetrachloro-p-benzoquinone...
  4. ncbi In vivo exposure of Dreissena polymorpha mussels to the quinones menadione and lawsone: menadione is more toxic to mussels than lawsone
    A M Osman
    Institute for Inland Water Management and Waste Water Treatment, PO Box 17, 8200 AA Lelystad, The Netherlands
    J Appl Toxicol 24:135-41. 2004
    ....
  5. ncbi Kinetic and stability studies on the chloroperoxidase complexes in presence of tert-butyl hydroperoxide
    Paolo Toti
    , Dipartimento di Fisiologia e Biochimica, , Via S. Zeno 51, 56027 Pisa, Italy
    Biophys Chem 113:105-13. 2005
    ..A second group of inactivation constants (j(3) and K) was obtained, which is sufficiently close to the first two, thus verifying that the decreasing of enzyme absorbance corresponds to the decay of activity...
  6. ncbi A linearization method for low catalytic activity enzyme kinetic analysis
    Paolo Toti
    Department of Physiology and Biochemistry, Biochemistry Unit, University of Pisa, Italy
    Biophys Chem 114:245-51. 2005
    ..This plot could also be useful to the study of abenzyme kinetics provided the concentration of the latter is either higher or equal than K(m) value...