J P Langedijk

Summary

Affiliation: Institute for Animal Science and Health
Country: The Netherlands

Publications

  1. ncbi Proposed three-dimensional model for the attachment protein G of respiratory syncytial virus
    J P Langedijk
    Department of Bovine Virology, Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
    J Gen Virol 77:1249-57. 1996
  2. ncbi Type-specific serologic diagnosis of respiratory syncytial virus infection, based on a synthetic peptide of the attachment protein G
    J P Langedijk
    Department of Bovine Virology, Institute for Animal Science and Health ID DLO, Lelystad, Netherlands
    J Immunol Methods 193:157-66. 1996
  3. pmc Antigenic structure of the central conserved region of protein G of bovine respiratory syncytial virus
    J P Langedijk
    Department of Mammalian Virology, The Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
    J Virol 71:4055-61. 1997
  4. pmc A subtype-specific peptide-based enzyme immunoassay for detection of antibodies to the G protein of human respiratory syncytial virus is more sensitive than routine serological tests
    J P Langedijk
    Department of Mammalian Virology, Institute for Animal Science and Health, Lelystad, The Netherlands
    J Clin Microbiol 35:1656-60. 1997
  5. ncbi Structural homology of the central conserved region of the attachment protein G of respiratory syncytial virus with the fourth subdomain of 55-kDa tumor necrosis factor receptor
    J P Langedijk
    Department of Mammalian Virology, Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
    Virology 243:293-302. 1998
  6. ncbi A bovine respiratory syncytial virus strain with mutations in subgroup-specific antigenic domains of the G protein induces partial heterologous protection in cattle
    R S Schrijver
    Department of Mammalian Virology, DLO Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
    Vet Microbiol 63:159-75. 1998
  7. pmc Enzyme-linked immunosorbent assay using a virus type-specific peptide based on a subdomain of envelope protein E(rns) for serologic diagnosis of pestivirus infections in swine
    J P Langedijk
    Department of Mammalian Virology, Institute for Animal Science and Health ID Lelystad, Edelhertweg 15, P O Box 65, 8200 AB Lelystad, The Netherlands
    J Clin Microbiol 39:906-12. 2001
  8. pmc Sequence and structure alignment of Paramyxoviridae attachment proteins and discovery of enzymatic activity for a morbillivirus hemagglutinin
    J P Langedijk
    Department of Mammalian Virology, The Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
    J Virol 71:6155-67. 1997

Detail Information

Publications8

  1. ncbi Proposed three-dimensional model for the attachment protein G of respiratory syncytial virus
    J P Langedijk
    Department of Bovine Virology, Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
    J Gen Virol 77:1249-57. 1996
    ..This model provides a structural explanation for the location and molecular details of important antigenic sites...
  2. ncbi Type-specific serologic diagnosis of respiratory syncytial virus infection, based on a synthetic peptide of the attachment protein G
    J P Langedijk
    Department of Bovine Virology, Institute for Animal Science and Health ID DLO, Lelystad, Netherlands
    J Immunol Methods 193:157-66. 1996
    ..This study shows that peptides, corresponding to the central hydrophobic region of the attachment protein G of several RSVs, can be used successfully as antigens in highly specific and sensitive immunoassays...
  3. pmc Antigenic structure of the central conserved region of protein G of bovine respiratory syncytial virus
    J P Langedijk
    Department of Mammalian Virology, The Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
    J Virol 71:4055-61. 1997
    ..Additionally, analysis of the epitopes demonstrated that two point mutations at positions 180 and 205 define the preliminary classification of BRSV subgroups...
  4. pmc A subtype-specific peptide-based enzyme immunoassay for detection of antibodies to the G protein of human respiratory syncytial virus is more sensitive than routine serological tests
    J P Langedijk
    Department of Mammalian Virology, Institute for Animal Science and Health, Lelystad, The Netherlands
    J Clin Microbiol 35:1656-60. 1997
    ..The G-peptide ELISA appeared to be more sensitive than conventional tests for the detection of HRSV antibody titer rises...
  5. ncbi Structural homology of the central conserved region of the attachment protein G of respiratory syncytial virus with the fourth subdomain of 55-kDa tumor necrosis factor receptor
    J P Langedijk
    Department of Mammalian Virology, Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
    Virology 243:293-302. 1998
    ..Although the homology suggests that the cystine noose of RSV-G may interfere with the antiviral and apoptotic effect of TNF, the biological activity remains to be proven...
  6. ncbi A bovine respiratory syncytial virus strain with mutations in subgroup-specific antigenic domains of the G protein induces partial heterologous protection in cattle
    R S Schrijver
    Department of Mammalian Virology, DLO Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
    Vet Microbiol 63:159-75. 1998
    ..We conclude that complete BRSV virus can partially protect against a BRSV infection with a strain that contains an antigenic dissimilar G protein...
  7. pmc Enzyme-linked immunosorbent assay using a virus type-specific peptide based on a subdomain of envelope protein E(rns) for serologic diagnosis of pestivirus infections in swine
    J P Langedijk
    Department of Mammalian Virology, Institute for Animal Science and Health ID Lelystad, Edelhertweg 15, P O Box 65, 8200 AB Lelystad, The Netherlands
    J Clin Microbiol 39:906-12. 2001
    ..Because the peptide is a fragment of the E(rns) protein, it can be used to differentiate between infected and vaccinated animals when a vaccine based on the E2 protein, which is another pestivirus envelope protein, is used...
  8. pmc Sequence and structure alignment of Paramyxoviridae attachment proteins and discovery of enzymatic activity for a morbillivirus hemagglutinin
    J P Langedijk
    Department of Mammalian Virology, The Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
    J Virol 71:6155-67. 1997
    ..The enzymatic activity may indicate a general infection mechanism for respiratory viruses, and the active site may prove to be a new target for antiviral compounds...