Research Topics
| J P LangedijkSummaryAffiliation: Institute for Animal Science and Health Country: The Netherlands Publications
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Detail Information
Publications
Proposed three-dimensional model for the attachment protein G of respiratory syncytial virusJ P Langedijk
Department of Bovine Virology, Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
J Gen Virol 77:1249-57. 1996..This model provides a structural explanation for the location and molecular details of important antigenic sites...- Type-specific serologic diagnosis of respiratory syncytial virus infection, based on a synthetic peptide of the attachment protein GJ P Langedijk
Department of Bovine Virology, Institute for Animal Science and Health ID DLO, Lelystad, Netherlands
J Immunol Methods 193:157-66. 1996..This study shows that peptides, corresponding to the central hydrophobic region of the attachment protein G of several RSVs, can be used successfully as antigens in highly specific and sensitive immunoassays... - Antigenic structure of the central conserved region of protein G of bovine respiratory syncytial virusJ P Langedijk
Department of Mammalian Virology, The Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
J Virol 71:4055-61. 1997..Additionally, analysis of the epitopes demonstrated that two point mutations at positions 180 and 205 define the preliminary classification of BRSV subgroups... - A subtype-specific peptide-based enzyme immunoassay for detection of antibodies to the G protein of human respiratory syncytial virus is more sensitive than routine serological testsJ P Langedijk
Department of Mammalian Virology, Institute for Animal Science and Health, Lelystad, The Netherlands
J Clin Microbiol 35:1656-60. 1997..The G-peptide ELISA appeared to be more sensitive than conventional tests for the detection of HRSV antibody titer rises... - Structural homology of the central conserved region of the attachment protein G of respiratory syncytial virus with the fourth subdomain of 55-kDa tumor necrosis factor receptorJ P Langedijk
Department of Mammalian Virology, Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
Virology 243:293-302. 1998..Although the homology suggests that the cystine noose of RSV-G may interfere with the antiviral and apoptotic effect of TNF, the biological activity remains to be proven... - A bovine respiratory syncytial virus strain with mutations in subgroup-specific antigenic domains of the G protein induces partial heterologous protection in cattleR S Schrijver
Department of Mammalian Virology, DLO Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
Vet Microbiol 63:159-75. 1998..We conclude that complete BRSV virus can partially protect against a BRSV infection with a strain that contains an antigenic dissimilar G protein... - Enzyme-linked immunosorbent assay using a virus type-specific peptide based on a subdomain of envelope protein E(rns) for serologic diagnosis of pestivirus infections in swineJ P Langedijk
Department of Mammalian Virology, Institute for Animal Science and Health ID Lelystad, Edelhertweg 15, P O Box 65, 8200 AB Lelystad, The Netherlands
J Clin Microbiol 39:906-12. 2001..Because the peptide is a fragment of the E(rns) protein, it can be used to differentiate between infected and vaccinated animals when a vaccine based on the E2 protein, which is another pestivirus envelope protein, is used... - Sequence and structure alignment of Paramyxoviridae attachment proteins and discovery of enzymatic activity for a morbillivirus hemagglutininJ P Langedijk
Department of Mammalian Virology, The Institute for Animal Science and Health ID DLO, Lelystad, The Netherlands
J Virol 71:6155-67. 1997..The enzymatic activity may indicate a general infection mechanism for respiratory viruses, and the active site may prove to be a new target for antiviral compounds...